PinAPL-Py: A comprehensive web-application for the analysis of CRISPR/Cas9 screens
Spahn P, Bath T, Weiss R, Kim J, Esko J, Lewis N, Harismendy O. PinAPL-Py: A comprehensive web-application for the analysis of CRISPR/Cas9 screens. Scientific Reports 2017, 7: 15854. PMID: 29158538, PMCID: PMC5696473, DOI: 10.1038/s41598-017-16193-9.Peer-Reviewed Original ResearchConceptsCRISPR/Large-scale genetic screensCRISPR/Cas9Publication-ready plotsSequence quality controlPlatform-independent analysisUser-friendly implementationLarge sequencing datasetsGenetic screenAnalysis optionsFunctional genomicsPooled screensSgRNA libraryBioinformatics toolsSequencing datasetsComprehensive functionalityExperimental biologistsBioinformatics expertiseArt toolsCustom libraryLimited functionalityTest datasetSequence extractionGene rankingIncreased popularity