1997
Effect of left ventricular function on the assessment of myocardial viability by technectium-99m sestamibi and correlation with positron emission tomography in patients with healed myocardial infarcts or stable angina pectoris, or both
Arrighi J, Ng C, Dey H, Wackers F, Soufer R. Effect of left ventricular function on the assessment of myocardial viability by technectium-99m sestamibi and correlation with positron emission tomography in patients with healed myocardial infarcts or stable angina pectoris, or both. The American Journal Of Cardiology 1997, 80: 1007-1013. PMID: 9352969, DOI: 10.1016/s0002-9149(97)00594-8.Peer-Reviewed Original ResearchConceptsCoronary artery diseasePositron emission tomographyLV dysfunctionArtery diseaseGroup 2Myocardial viabilityGroup 1Ejection fractionModerate coronary artery diseaseEmission tomographyModerate LV dysfunctionSevere LV dysfunctionStable angina pectorisLV ejection fractionGlobal LV dysfunctionAccuracy of technetiumSingle photon emissionSemiquantitative SPECTVentricular dysfunctionViability detectionAngina pectorisVentricular functionReduced perfusionSestamibi SPECTMyocardial infarct
1995
Myocardial perfusion imaging with 99mTc tetrofosmin. Comparison to 201Tl imaging and coronary angiography in a phase III multicenter trial. Tetrofosmin International Trial Study Group.
Zaret B, Rigo P, Wackers F, Hendel R, Braat S, Iskandrian A, Sridhara B, Jain D, Itti R, Serafini A, Goris M, Lahiri A. Myocardial perfusion imaging with 99mTc tetrofosmin. Comparison to 201Tl imaging and coronary angiography in a phase III multicenter trial. Tetrofosmin International Trial Study Group. Circulation 1995, 91: 313-9. PMID: 7805233, DOI: 10.1161/01.cir.91.2.313.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseArtery diseaseTetrofosmin imagingCoronary angiographyMyocardial perfusionTetrofosmin imagesHealthy subjectsPhase III multicenter trialConventional myocardial perfusionLower likelihoodCentral core laboratoryMyocardial perfusion abnormalitiesNew 99mTcPeak heart rateNegative predictive accuracyMyocardial perfusion imagingNew myocardial imaging agentPlanar 201TlMulticenter trialNormalcy rateCoronary angiogramDouble productPerfusion abnormalitiesMyocardial imaging agentRadiotracer injection
1993
Myocardial risk area defined by technetium-99m sestamibi imaging during percutaneous transluminal coronary angioplasty: Comparison with coronary angiography
Haronian H, Remetz M, Sinusas A, Baron J, Miller H, Cleman M, Zaret B, Wackers F. Myocardial risk area defined by technetium-99m sestamibi imaging during percutaneous transluminal coronary angioplasty: Comparison with coronary angiography. Journal Of The American College Of Cardiology 1993, 22: 1033-1043. PMID: 8409038, DOI: 10.1016/0735-1097(93)90413-u.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAngioplasty, Balloon, CoronaryClinical ProtocolsCollateral CirculationCoronary AngiographyCoronary DiseaseEvaluation Studies as TopicFemaleHumansMaleMiddle AgedMyocardial InfarctionObserver VariationPredictive Value of TestsPrognosisReproducibility of ResultsRisk FactorsSeverity of Illness IndexTechnetium Tc 99m SestamibiTomography, Emission-Computed, Single-PhotonConceptsMyocardial risk areaCoronary angiographyCoronary angioplastyQuantitative myocardial perfusionMyocardial perfusionMyocardial areaPercutaneous transluminal coronary angioplastyAngiographic risk scoresSmall risk areasTransluminal coronary angioplastyCoronary artery diseaseCoronary artery stenosisInitial myocardial uptakeAngioplasty balloon inflationArtery diseaseLeft anteriorNonperfused areaArtery stenosisCoronary anatomyCoronary arteryBalloon inflationPatient managementMyocardial uptakeRisk scoreAngioplasty
1990
Serial changes in myocardial perfusion using tomographic technetium-99m-hexakis-2-methoxy-2-methylpropyl-isonitrile imaging following reperfusion therapy of myocardial infarction.
Pellikka P, Behrenbeck T, Verani M, Mahmarian J, Wackers F, Gibbons R. Serial changes in myocardial perfusion using tomographic technetium-99m-hexakis-2-methoxy-2-methylpropyl-isonitrile imaging following reperfusion therapy of myocardial infarction. Journal Of Nuclear Medicine 1990, 31: 1269-75. PMID: 2143527.Peer-Reviewed Original ResearchConceptsReperfusion therapyMyocardial infarctionTc-sestamibiAcute reperfusion therapyFirst myocardial infarctionSuccessful reperfusionTomographic myocardial perfusion imagesSerial changesHypoperfused myocardiumMean decreaseFinal studyMyocardial perfusionPatientsSignificant improvementMyocardial perfusion imagesSecond studyTherapyPerfusion imagesReperfusionInfarctionPerfusionFurther decreaseHrTomographic imagingImaging
1981
Multigated equilibrium radionuclide angiocardiography: improved detection of left ventricular wall motion abnormalities and aneurysms by the addition of the left lateral view.
Kelly MJ, Giles RW, Simon TR, Berger HJ, Langou RA, Zaret BL, Wackers FJ. Multigated equilibrium radionuclide angiocardiography: improved detection of left ventricular wall motion abnormalities and aneurysms by the addition of the left lateral view. Radiology 1981, 139: 167-73. PMID: 7208919, DOI: 10.1148/radiology.139.1.7208919.Peer-Reviewed Original Research
1979
Multiple gated cardiac blood pool imaging for left ventricular ejection fraction: Validation of the technique and assessment of variability
Wackers F, Berger H, Johnstone D, Goldman L, Reduto L, Langou R, Gottschalk A, Zaret B, Quartararo L, Pytlik L. Multiple gated cardiac blood pool imaging for left ventricular ejection fraction: Validation of the technique and assessment of variability. The American Journal Of Cardiology 1979, 43: 1159-1166. PMID: 443176, DOI: 10.1016/0002-9149(79)90148-6.Peer-Reviewed Original ResearchMeSH KeywordsAngiocardiographyCardiac VolumeComputersEvaluation Studies as TopicHeartHeart DiseasesHumansMethodsMyocardial ContractionRadionuclide ImagingStatistics as TopicTechnetiumConceptsEjection fractionAbsolute ejection fractionLeft ventricular ejection fractionCardiac blood pool imagingVentricular ejection fractionFirst-pass radionuclide angiocardiographyBlood pool imagingRadionuclide angiocardiographyContrast angiographyRepeat studyPatientsAbnormal patientsSeparate daysInterobserver variabilitySame dayDifferent daysDaysAngiographyAngiocardiography
1978
Prevalence of right ventricular involvement in inferior wall infarction assessed with myocardial imaging with thallium-201 and technetium-99m pyrophosphate
Wackers F, Lie K, Sokole E, Res J, Van Der Schoot J, Durrer D. Prevalence of right ventricular involvement in inferior wall infarction assessed with myocardial imaging with thallium-201 and technetium-99m pyrophosphate. The American Journal Of Cardiology 1978, 42: 358-362. PMID: 210648, DOI: 10.1016/0002-9149(78)90928-1.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedDiphosphatesEvaluation Studies as TopicFemaleHeart VentriclesHumansMaleMiddle AgedMyocardial InfarctionRadioisotopesRadionuclide ImagingTechnetiumThalliumConceptsRight ventricular involvementAcute inferior wall infarctionInferior wall infarctionVentricular involvementThallium-201Myocardial imagingSevere right ventricular failurePump failurePositive pyrophosphate scansSevere pump failureRight ventricular failureSubgroup of patientsThallium-201 defectsPyrophosphate scanCardiogenic shockVentricular dysfunctionVentricular failureConsecutive patientsConsecutive seriesClassic signsPatientsClinical relevanceInfarctionNonivasive methodVolume loading
1976
Value and Limitations of Thallium-201 Scintigraphy in the Acute Phase of Myocardial Infarction
Wackers F, Sokole E, Samson G, Schoot J, Lie K, Liem K, Wellens H. Value and Limitations of Thallium-201 Scintigraphy in the Acute Phase of Myocardial Infarction. New England Journal Of Medicine 1976, 295: 1-5. PMID: 1272283, DOI: 10.1056/nejm197607012950101.Peer-Reviewed Original Research