2023
Outcomes Associated with Sodium-Glucose Cotransporter-2 Inhibitor Use in Acute Heart Failure Hospitalizations Complicated by AKI
Aklilu A, Kumar S, Yamamoto Y, Moledina D, Sinha F, Testani J, Wilson F. Outcomes Associated with Sodium-Glucose Cotransporter-2 Inhibitor Use in Acute Heart Failure Hospitalizations Complicated by AKI. Kidney360 2023, 4: 1371-1381. PMID: 37644648, PMCID: PMC10615381, DOI: 10.34067/kid.0000000000000250.Peer-Reviewed Original ResearchConceptsAcute kidney injuryHeart failure hospitalizationSodium-glucose cotransporter-2 inhibitor useSodium-glucose cotransporter 2 inhibitorsAcute heart failure hospitalizationCotransporter 2 inhibitorsCox regression analysisRenal recoveryFailure hospitalizationAKI diagnosisKidney injuryInhibitor useLower riskStage 5 chronic kidney diseaseTime-varying Cox regression analysisKidney Disease Improving Global OutcomesInverse probability-weighted analysisMulticenter retrospective cohort studyMultivariable Cox regression analysisStage 5 CKDAcute heart failureRetrospective cohort studyChronic kidney diseaseKidney function recoveryGlomerular filtration rate
2016
Proton Pump Inhibitor Use and the Risk of Chronic Kidney Disease
Lazarus B, Chen Y, Wilson FP, Sang Y, Chang AR, Coresh J, Grams ME. Proton Pump Inhibitor Use and the Risk of Chronic Kidney Disease. JAMA Internal Medicine 2016, 176: 238-246. PMID: 26752337, PMCID: PMC4772730, DOI: 10.1001/jamainternmed.2015.7193.Peer-Reviewed Original ResearchConceptsIncident chronic kidney diseaseChronic kidney diseaseGlomerular filtration rateProton pump inhibitorsPPI useAtherosclerosis RiskInhibitor useFiltration rateReplication cohortPPI usersKidney diseaseCommunity studyHigh riskIncidence of CKDPropensity score-matched nonusersProton pump inhibitor useAcute interstitial nephritisReceptor antagonist usersReceptor antagonist usePopulation-based cohortNew-user designGeisinger Health SystemAntihypertensive medicationsPPI dosingAntagonist use