2023
Expert Consensus on the Nephrotoxic Potential of 195 Medications in the Non-intensive Care Setting: A Modified Delphi Method
Stottlemyer B, Abebe K, Palevsky P, Fried L, Schulman I, Parikh C, Poggio E, Siew E, Gutierrez O, Horwitz E, Weir M, Wilson F, Kane-Gill S. Expert Consensus on the Nephrotoxic Potential of 195 Medications in the Non-intensive Care Setting: A Modified Delphi Method. Drug Safety 2023, 46: 677-687. PMID: 37223847, PMCID: PMC10208182, DOI: 10.1007/s40264-023-01312-5.Peer-Reviewed Original ResearchConceptsNon-intensive care settingNephrotoxic medicationsCare settingsNephrotoxic potentialAcute kidney injury developmentKidney injury developmentFuture clinical evaluationComprehensive literature searchIll patientsPrimary outcomeNephrotoxic effectsResultsA totalClinical evaluationClinical consensusMedicationsExpert consensusInjury developmentLiterature searchPharmacist expertiseNephrotoxicParticipants' recommendationsModified Delphi MethodStandardized listConsecutive ratingsSetting
2022
Excessive Blood Pressure Response to Clonidine in Hospitalized Patients With Asymptomatic Severe Hypertension
Hanna J, Ghazi L, Yamamoto Y, Simonov M, Shah T, Wilson F, Peixoto A. Excessive Blood Pressure Response to Clonidine in Hospitalized Patients With Asymptomatic Severe Hypertension. American Journal Of Hypertension 2022, 35: 433-440. PMID: 35038322, PMCID: PMC9088839, DOI: 10.1093/ajh/hpac004.Peer-Reviewed Original ResearchConceptsAsymptomatic severe hypertensionBlood pressure responseSevere hypertensionHospitalized patientsPressure responseExcessive blood pressure responseMean arterial pressure reductionMAP reductionAcute kidney injuryBlood pressure declineArterial pressure reductionHours of administrationClonidine doseKidney injuryPrimary endpointAdverse eventsIschemic eventsBlood pressureIll patientsClinical groundsMedian timePatient sexFemale sexVascular diseaseMultivariable model