2019
Does prior coronary angioplasty affect outcomes of surgical coronary revascularization? Insights from the STICH trial
Nicolau JC, Stevens SR, Al-Khalidi HR, Jatene FB, Furtado RHM, Dallan LAO, Lisboa LAF, Desvigne-Nickens P, Haddad H, Jolicoeur EM, Petrie MC, Doenst T, Michler RE, Ohman EM, Maddury J, Ali I, Deja MA, Rouleau JL, Velazquez EJ, Hill JA. Does prior coronary angioplasty affect outcomes of surgical coronary revascularization? Insights from the STICH trial. International Journal Of Cardiology 2019, 291: 36-41. PMID: 30929973, PMCID: PMC6579621, DOI: 10.1016/j.ijcard.2019.03.029.Peer-Reviewed Original ResearchConceptsPrior percutaneous coronary interventionPercutaneous coronary interventionLeft ventricular ejection fractionSTICH trialCV hospitalizationCV mortalityCause mortalityMedical treatmentSuperiority of CABGOutcomes of patientsSurgical coronary revascularizationCoronary artery bypassVentricular ejection fractionArtery bypassCoronary revascularizationCoronary interventionCoronary angioplastyEjection fractionMedian timeWorse prognosisRandomized treatmentCABGHospitalizationMortalityPatients
2016
Reassessment of Cardiac Function and Implantable Cardioverter-Defibrillator Use Among Medicare Patients With Low Ejection Fraction After Myocardial Infarction
Pokorney SD, Miller AL, Chen AY, Thomas L, Fonarow GC, de Lemos JA, Al-Khatib SM, Velazquez EJ, Peterson ED, Wang TY. Reassessment of Cardiac Function and Implantable Cardioverter-Defibrillator Use Among Medicare Patients With Low Ejection Fraction After Myocardial Infarction. Circulation 2016, 135: 38-47. PMID: 27881561, DOI: 10.1161/circulationaha.116.022359.Peer-Reviewed Original ResearchMeSH KeywordsAgedDatabases, FactualDefibrillators, ImplantableFemaleHeart VentriclesHumansMagnetic Resonance ImagingMaleMedicareMyocardial InfarctionMyocardial RevascularizationProportional Hazards ModelsRegistriesRetrospective StudiesStroke VolumeSurvival RateTomography, X-Ray ComputedUltrasonographyUnited StatesConceptsLow ejection fractionEjection fractionICD implantationMyocardial infarctionMI admissionsRevascularization statusImplantable cardioverter-defibrillator (ICD) useACTION Registry-GWTGICD implantation ratesMultivariable Cox modelPost-MI patientsYears of ageImplantation rateCardiac functionMedicare patientsCox modelPatientsAdmissionHigher likelihoodInfarctionImplantationAssociationYearsStatusICD
2015
Response to Letter Regarding Article, “Surgical Revascularization Is Associated With Maximal Survival in Patients With Ischemic Mitral Regurgitation
Castleberry AW, Williams JB, Daneshmand MA, Honeycutt E, Shaw LK, Samad Z, Lopes RD, Alexander JH, Mathew JP, Velazquez EJ, Milano CA, Smith PK. Response to Letter Regarding Article, “Surgical Revascularization Is Associated With Maximal Survival in Patients With Ischemic Mitral Regurgitation. Circulation 2015, 131: e378-e379. PMID: 25779550, PMCID: PMC5126645, DOI: 10.1161/circulationaha.114.013125.Peer-Reviewed Original ResearchMeSH KeywordsFemaleHumansMaleMitral Valve InsufficiencyMyocardial IschemiaMyocardial RevascularizationRevascularization in Severe Left Ventricular Dysfunction
Velazquez EJ, Bonow RO. Revascularization in Severe Left Ventricular Dysfunction. Journal Of The American College Of Cardiology 2015, 65: 615-624. PMID: 25677320, DOI: 10.1016/j.jacc.2014.10.070.Peer-Reviewed Original ResearchMeSH KeywordsEchocardiographyHumansMyocardial RevascularizationSeverity of Illness IndexTreatment OutcomeVentricular Dysfunction, LeftVentricular Function, LeftConceptsLeft ventricular systolic dysfunctionVentricular systolic dysfunctionShort-term riskSurgical revascularizationSystolic dysfunctionSevere left ventricular systolic dysfunctionCoronary artery bypass graft surgeryArtery bypass graft surgeryHigh-risk patient populationBypass graft surgeryReduced ejection fractionCornerstone of treatmentHigh-risk patientsMitral valve surgerySurgical ventricular reconstructionGreater short-term riskImplantable device therapyQuality of lifeMultivessel diseaseGraft surgeryValve surgerySurgery needDevice therapyEjection fractionHeart failure
2014
Surgical Revascularization Is Associated With Maximal Survival in Patients With Ischemic Mitral Regurgitation
Castleberry AW, Williams JB, Daneshmand MA, Honeycutt E, Shaw LK, Samad Z, Lopes RD, Alexander JH, Mathew JP, Velazquez EJ, Milano CA, Smith PK. Surgical Revascularization Is Associated With Maximal Survival in Patients With Ischemic Mitral Regurgitation. Circulation 2014, 129: 2547-2556. PMID: 24744275, PMCID: PMC4142433, DOI: 10.1161/circulationaha.113.005223.Peer-Reviewed Original ResearchMeSH KeywordsAgedCoronary Artery BypassDatabases, BibliographicFemaleFollow-Up StudiesHeart Valve Prosthesis ImplantationHumansKaplan-Meier EstimateMaleMiddle AgedMitral ValveMitral Valve InsufficiencyMyocardial IschemiaMyocardial RevascularizationPercutaneous Coronary InterventionProportional Hazards ModelsRetrospective StudiesRisk FactorsSeverity of Illness IndexStentsConceptsIschemic mitral regurgitationPercutaneous coronary interventionMitral valve repairSignificant coronary artery diseaseSevere ischemic mitral regurgitationCoronary artery diseaseMitral regurgitationCoronary interventionValve repairMedical treatmentArtery diseaseTreatment strategiesLower mortalityMultivariable Cox proportional hazards analysisCox proportional hazards analysisCoronary artery bypassMitral valve surgeryKaplan-Meier methodProportional hazards analysisMitral regurgitation severitySurgical revascularizationArtery bypassValve surgeryOptimal treatmentCABG
2012
Myocardial Imaging Should Not Exclude Patients With Ischemic Heart Failure From Coronary Revascularization
Velazquez EJ. Myocardial Imaging Should Not Exclude Patients With Ischemic Heart Failure From Coronary Revascularization. Circulation Cardiovascular Imaging 2012, 5: 271-279. PMID: 22438425, PMCID: PMC3878903, DOI: 10.1161/circimaging.111.964650.Peer-Reviewed Original ResearchMeSH KeywordsDiagnostic ImagingHeart FailureHumansMaleMyocardial IschemiaMyocardial RevascularizationMyocardiumPatient Selection
2003
Revascularization in patients with coronary artery disease, left ventricular dysfunction, and viability: a meta-analysis
Bourque JM, Hasselblad V, Velazquez EJ, Borges-Neto S, O'Connor CM. Revascularization in patients with coronary artery disease, left ventricular dysfunction, and viability: a meta-analysis. American Heart Journal 2003, 146: 621-627. PMID: 14564314, DOI: 10.1016/s0002-8703(03)00428-9.Peer-Reviewed Original ResearchMeSH KeywordsCoronary Artery DiseaseFemaleHumansMaleMiddle AgedMyocardial RevascularizationOdds RatioVentricular Dysfunction, LeftRadionuclide viability testing: should it affect treatment strategy in patients with cardiomyopathy and significant coronary artery disease?
Bourque JM, Velazquez EJ, Borges-Neto S, Shaw LK, Whellan DJ, O’Connor C. Radionuclide viability testing: should it affect treatment strategy in patients with cardiomyopathy and significant coronary artery disease? American Heart Journal 2003, 145: 758-767. PMID: 12766731, DOI: 10.1016/s0002-8703(02)94818-0.Peer-Reviewed Original ResearchMeSH KeywordsCoronary DiseaseFemaleFluorodeoxyglucose F18Heart FailureHumansMaleMyocardial RevascularizationProspective StudiesRadiopharmaceuticalsRetrospective StudiesSurvival RateThallium RadioisotopesTomography, Emission-ComputedTomography, Emission-Computed, Single-PhotonVentricular Dysfunction, LeftConceptsSignificant coronary artery diseaseCoronary artery diseaseLong-term mortalityArtery diseaseSurvival rateHeart failureTreatment strategiesImpaired left ventricular functionLong-term mortality ratesIschemic heart failureLeft ventricular functionIntermediate survival ratesNuclear imaging studiesLack of randomizationLower survival rateEjection fractionVentricular functionViable myocardiumReferral biasStudy protocolTreatment allocationLarge cohortPrognostic studiesMortality ratePatients