1986
Cell-mediated immunity to myelin-associated glycoprotein, proteolipid protein, and myelin basic protein in multiple sclerosis
Johnson D, Hafler D, Fallis R, Lees M, Brady R, Quarles R, Weiner H. Cell-mediated immunity to myelin-associated glycoprotein, proteolipid protein, and myelin basic protein in multiple sclerosis. Journal Of Neuroimmunology 1986, 13: 99-108. PMID: 2428837, DOI: 10.1016/0165-5728(86)90053-6.Peer-Reviewed Original ResearchConceptsActive MS patientsMyelin basic proteinPeripheral blood lymphocytesMyelin antigensMS patientsControl subjectsActive MSMultiple sclerosisNeurologic diseaseProteolipid proteinStable multiple sclerosis patientsMean proliferative responseCell-mediated immunityMultiple sclerosis patientsBasic proteinStable MSOND groupSclerosis patientsT8 subsetsBlood lymphocytesLymphocyte stimulationProliferative responseProportion of individualsPatientsAntigen
1985
Decreased autologous mixed lymphocyte reaction in multiple sclerosis
Hafler D, Buchsbaum M, Weiner H. Decreased autologous mixed lymphocyte reaction in multiple sclerosis. Journal Of Neuroimmunology 1985, 9: 339-347. PMID: 2931449, DOI: 10.1016/s0165-5728(85)80034-5.Peer-Reviewed Original ResearchConceptsT4/T8 ratioHigh T4/T8 ratioT8 ratioMultiple sclerosisNormal controlsInactive patientsActive diseaseMS patientsAutologous mixed lymphocyte reactionActive MS patientsSubgroup of patientsT cell responsesT cell subsetsMultiple sclerosis patientsT4/T8Mixed lymphocyte reactionCentral nervous systemSclerosis patientsLymphocyte reactionAutoimmune diseasesT cellsPatientsNervous systemViral disordersAMLR