2024
Risk of Serious Adverse Gastrointestinal Events with Potassium Binders in Hospitalized Patients: A National Study
Holleck J, Han L, Skanderson M, Bastian L, Gunderson C, Brandt C, Perkal M, Chang J, Akgün K. Risk of Serious Adverse Gastrointestinal Events with Potassium Binders in Hospitalized Patients: A National Study. Journal Of General Internal Medicine 2024, 1-7. PMID: 39103605, DOI: 10.1007/s11606-024-08979-1.Peer-Reviewed Original ResearchAdjusted odds ratiosSodium zirconium cyclosilicateU.S. Department of Veterans Affairs healthcare systemDepartment of Veterans Affairs healthcare systemVA Corporate Data WarehouseVeterans Affairs Healthcare SystemCorporate Data WarehousePotassium bindersHospitalized patientsGI eventsHealthcare systemOdds ratioAdverse GI eventsSodium polystyrene sulfonateNational studyPotassium-binding drugsComparative riskAdverse gastrointestinal eventsGI adverse eventsTreatment of hyperkalemiaZirconium cyclosilicateGastrointestinal eventsPatiromerAdverse events
2022
Pharmacogenomics driven decision support prototype with machine learning: A framework for improving patient care
Kidwai-Khan F, Rentsch C, Pulk R, Alcorn C, Brandt C, Justice A. Pharmacogenomics driven decision support prototype with machine learning: A framework for improving patient care. Frontiers In Big Data 2022, 5: 1059088. PMID: 36458283, PMCID: PMC9705957, DOI: 10.3389/fdata.2022.1059088.Peer-Reviewed Original ResearchK-Nearest NeighborSupport vector machinePreventable adverse eventsDecision support mechanismAdverse eventsCurrent medicationsExtreme gradient boostingPredictive modelingSoftware interfaceMachine learningVeterans AffairsData integrationF1 scoreLarge integrated healthcare systemNearest NeighborPatient's current medicationsVector machineOutpatient clinic visitsRandom forestDecision treeGradient boostingAUC scoreComplex treatment decisionsEHR dataIntegrated healthcare system