2007
Severity of childhood trauma is predictive of cocaine relapse outcomes in women but not men
Hyman SM, Paliwal P, Chaplin TM, Mazure CM, Rounsaville BJ, Sinha R. Severity of childhood trauma is predictive of cocaine relapse outcomes in women but not men. Drug And Alcohol Dependence 2007, 92: 208-216. PMID: 17900822, PMCID: PMC2233653, DOI: 10.1016/j.drugalcdep.2007.08.006.Peer-Reviewed Original ResearchMeSH KeywordsAdultAdult Survivors of Child AbuseChildChild Abuse, SexualCocaine-Related DisordersData Interpretation, StatisticalFemaleFollow-Up StudiesHumansInpatientsMaleMiddle AgedPredictive Value of TestsProspective StudiesPsychiatric Status Rating ScalesRecurrenceSex CharacteristicsSocioeconomic FactorsSubstance Abuse Treatment CentersSurveys and QuestionnairesConceptsOverall childhood traumaCocaine relapse outcomesChildhood traumaEmotional abuseRelapse outcomesChildhood emotional abuseCocaine treatment outcomesCocaine-dependent menCocaine-dependent adultsCocaine relapseAssociation of severityRisk of relapseSexual abusePhysical abuseGender-specific effectsInitial relapseDay cocaineCocaine dependenceDependent adultsInpatient SampleInpatient treatmentTreatment outcomesGreater severityAbuseDependent men
2004
Childhood maltreatment as a risk factor for adult cardiovascular disease and depression.
Batten SV, Aslan M, Maciejewski PK, Mazure CM. Childhood maltreatment as a risk factor for adult cardiovascular disease and depression. The Journal Of Clinical Psychiatry 2004, 65: 249-54. PMID: 15003081, DOI: 10.4088/jcp.v65n0217.Peer-Reviewed Original ResearchConceptsCardiovascular diseaseRisk factorsChildhood maltreatmentAdult depressionMultiple logistic regression modelAdult cardiovascular diseasePotent risk factorEffective clinical assessmentNational Comorbidity SurveySignificant increaseU.S. National Comorbidity SurveyLogistic regression modelsSex differencesCardiovascular eventsRepresentative sampleClinical assessmentLifetime depressionDiseaseAdult HealthPhysical outcomesWomenDepressionChildhood abuseMenDemographic factors
1999
Childhood Sexual Abuse as a Risk Factor for Depression in Women: Psychosocial and Neurobiological Correlates
Weiss EL, Longhurst JG, Mazure CM. Childhood Sexual Abuse as a Risk Factor for Depression in Women: Psychosocial and Neurobiological Correlates. American Journal Of Psychiatry 1999, 156: 816-828. PMID: 10360118, DOI: 10.1176/ajp.156.6.816.Peer-Reviewed Original ResearchConceptsAdult-onset depressionChildhood sexual abuseEarly stressorsHPA axisSexual abuseAdrenal axis functionLong-term dysregulationMajor depressive disorderStress-induced dysregulationDepressive illnessAxis functionDepressed patientsDepressive disorderRisk factorsLong-term effectsHuman studiesManual searchNeurobiological correlatesPsychosocial mechanismsDepressionWomenEarly stressDysregulationSubsequent developmentDysregulation results
1997
Magnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse—a preliminary report
Bremner J, Randall P, Vermetten E, Staib L, Bronen R, Mazure C, Capelli S, McCarthy G, Innis R, Charney D. Magnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse—a preliminary report. Biological Psychiatry 1997, 41: 23-32. PMID: 8988792, PMCID: PMC3229101, DOI: 10.1016/s0006-3223(96)00162-x.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderLeft hippocampal volumeHippocampal volumeChildhood abuseAdult survivorsSmaller left hippocampal volumeAbuse-related posttraumatic stress disorderStress disorderSmaller hippocampal volumesCombat-related posttraumatic stress disorderMagnetic resonance imagingShort-term memoryHealthy subjectsYears of educationAlcohol abuseMagnetic resonance imaging-based measurementsComparison subjectsPTSD patientsImaging-based measurementsResonance imagingPatientsSexual abusePreliminary reportSurvivorsComparison region