2002
Photochemotherapy of vascular cells with 8‐methoxypsoralen and visible light: differential effects on endothelial and smooth muscle cells
Lee DM, Gasparro FP, Wang XJ, Kopec C, DeLeo K, Sumpio BE. Photochemotherapy of vascular cells with 8‐methoxypsoralen and visible light: differential effects on endothelial and smooth muscle cells. Photodermatology Photoimmunology & Photomedicine 2002, 18: 244-252. PMID: 12390666, DOI: 10.1034/j.1600-0781.2002.02770.x.Peer-Reviewed Original ResearchConceptsSmooth muscle cellsEndothelial cellsPercutaneous transluminal coronary angioplastyMuscle cellsTransluminal coronary angioplastyLong-term efficacyAortic smooth muscle cellsBovine aortic smooth muscle cellsDose-dependent fashionReversible inhibitionCoronary angioplastyIntermediate doseLow doseHigh doseSMC proliferationCell countVascular cellsDoseProliferation of ECsEC proliferationDifferential effectsProliferationCellular migrationPresent studySignificant effect
2000
Mitogen‐activated protein phosphorylation in endothelial cells exposed to hyperosmolar conditions
Duzgun S, Rasque H, Kito H, Azuma N, Li W, Basson M, Gahtan V, Dudrick S, Sumpio B. Mitogen‐activated protein phosphorylation in endothelial cells exposed to hyperosmolar conditions. Journal Of Cellular Biochemistry 2000, 76: 567-571. PMID: 10653976, DOI: 10.1002/(sici)1097-4644(20000315)76:4<567::aid-jcb5>3.0.co;2-w.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCalcium-Calmodulin-Dependent Protein KinasesCattleCell SizeEndothelium, VascularGlucoseJNK Mitogen-Activated Protein KinasesMannitolMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3Mitogen-Activated Protein KinasesOsmolar ConcentrationOsmotic PressureP38 Mitogen-Activated Protein KinasesPhosphorylationSignal TransductionSodium ChlorideTime FactorsUrea
1998
Induction of interleukin (IL)‐1α and β gene expression in human keratinocytes exposed to repetitive strain: Their role in strain‐induced keratinocyte proliferation and morphological change
Takei T, Kito H, Du W, Mills I, Sumpio B. Induction of interleukin (IL)‐1α and β gene expression in human keratinocytes exposed to repetitive strain: Their role in strain‐induced keratinocyte proliferation and morphological change. Journal Of Cellular Biochemistry 1998, 69: 95-103. PMID: 9548558, DOI: 10.1002/(sici)1097-4644(19980501)69:2<95::aid-jcb1>3.0.co;2-p.Peer-Reviewed Original ResearchConceptsIL-1 antibodyIL-1 alphaIL-1Keratinocyte proliferationIL-1 mRNA expressionKeratinocyte biologyIL-1 gene expressionInduction of interleukinIL-1 betaIL-1 expressionMorphological changesΒ gene expressionAutocrine regulationMRNA expressionBeta mRNAGene expressionBasal rateBasic cellular propertiesHuman keratinocytesAntibodiesKeratinocyte functionRepetitive strainNorthern blot analysisBlot analysisProliferationAtomic Force Microscopy on Living Cells: Aldosterone–Induced Localized Cell Swelling
Schneider SW, Pagel P, Storck J, Yano Y, Sumpio BE, Geibel JP, Oberleithner H. Atomic Force Microscopy on Living Cells: Aldosterone–Induced Localized Cell Swelling. Kidney & Blood Pressure Research 1998, 21: 256-258. PMID: 9762848, DOI: 10.1159/000025869.Peer-Reviewed Original Research
1997
Cyclic strain stimulates isoform‐specific PKC activation and translocation in cultured human keratinocytes
Takei T, Han O, Ikeda M, Male P, Mills I, Sumpio B. Cyclic strain stimulates isoform‐specific PKC activation and translocation in cultured human keratinocytes. Journal Of Cellular Biochemistry 1997, 67: 327-337. PMID: 9361188, DOI: 10.1002/(sici)1097-4644(19971201)67:3<327::aid-jcb5>3.0.co;2-y.Peer-Reviewed Original ResearchRAPID ALDOSTERONE‐INDUCED CELL VOLUME INCREASE OF ENDOTHELIAL CELLS MEASURED BY THE ATOMIC FORCE MICROSCOPE
SCHNEIDER S, YANO Y, SUMPIO B, JENA B, GEIBEL J, GEKLE M, OBERLEITHNER H. RAPID ALDOSTERONE‐INDUCED CELL VOLUME INCREASE OF ENDOTHELIAL CELLS MEASURED BY THE ATOMIC FORCE MICROSCOPE. Cell Biology International 1997, 21: 759-768. PMID: 9768474, DOI: 10.1006/cbir.1997.0220.Peer-Reviewed Original ResearchConceptsEndothelial cellsAddition of aldosteroneArterial blood pressureNon-genomic effectsCultured endothelial cellsBlood pressureMineralocorticoid hormonesHormone exposureAldosteroneCell volumeHuman leukocytesIntracellular electrolytesTransient swellingTriphosphate productionIntracellular pHLeukocytesVolume increaseBovine aortaContinuous presenceCellsPlasma membraneEffect of strain on human keratinocytes in vitro
Takei T, Rivas‐Gotz C, Delling C, Koo J, Mills I, McCarthy T, Centrella M, Sumpio B. Effect of strain on human keratinocytes in vitro. Journal Of Cellular Physiology 1997, 173: 64-72. PMID: 9326450, DOI: 10.1002/(sici)1097-4652(199710)173:1<64::aid-jcp8>3.0.co;2-h.Peer-Reviewed Original Research
1996
Amplitude‐dependent modulation of brush border enzymes and proliferation by cyclic strain in human intestinal Caco‐2 monolayers
Basson M, Di Li G, Hong F, Han O, Sumpio B. Amplitude‐dependent modulation of brush border enzymes and proliferation by cyclic strain in human intestinal Caco‐2 monolayers. Journal Of Cellular Physiology 1996, 168: 476-488. PMID: 8707883, DOI: 10.1002/(sici)1097-4652(199608)168:2<476::aid-jcp26>3.0.co;2-#.Peer-Reviewed Original Research