2005
Differential effects of orbital and laminar shear stress on endothelial cells
Dardik A, Chen L, Frattini J, Asada H, Aziz F, Kudo FA, Sumpio BE. Differential effects of orbital and laminar shear stress on endothelial cells. Journal Of Vascular Surgery 2005, 41: 869-880. PMID: 15886673, DOI: 10.1016/j.jvs.2005.01.020.Peer-Reviewed Original ResearchNicotine induces mitogen-activated protein kinase dependent vascular smooth muscle cell migration
Di Luozzo G, Pradhan S, Dhadwal AK, Chen A, Ueno H, Sumpio BE. Nicotine induces mitogen-activated protein kinase dependent vascular smooth muscle cell migration. Atherosclerosis 2005, 178: 271-277. PMID: 15694934, DOI: 10.1016/j.atherosclerosis.2004.09.017.Peer-Reviewed Original ResearchConceptsVascular smooth muscle cell migrationSmooth muscle cell migrationMuscle cell migrationInhibitors of p38VSMC migrationMitogen-activated protein kinaseEndothelial cellsDevelopment of atherosclerosisEffects of nicotineCell migrationWestern blotting methodInjury modelVascular endotheliumCigarette smokeBoyden chamber chemotaxis assaysAortic VSMCsChemotactic effectMAPKs p38NicotineChemoattractant moleculesChemotaxis assaysCellular mechanismsUltrastructural changesVSMCP44/42 activation
2004
Do estrogen effects on blood vessels translate into clinically significant atheroprotection?
Pradhan S, Sumpio BE. Do estrogen effects on blood vessels translate into clinically significant atheroprotection? Journal Of The American College Of Surgeons 2004, 198: 462-474. PMID: 14992749, DOI: 10.1016/j.jamcollsurg.2003.09.026.Peer-Reviewed Original Research
2002
Effect of gender on outcome following infrainguinal bypass graft surgery: a systematic review.
Frangos SG, Kilaru S, Sumpio BE, Gahtan V. Effect of gender on outcome following infrainguinal bypass graft surgery: a systematic review. Connecticut Medicine 2002, 66: 137-44. PMID: 11957765.Peer-Reviewed Original Research
2001
Nicotine: a review of its role in atherosclerosis1 1No competing interests declared.
Kilaru S, Frangos S, Chen A, Gortler D, Dhadwal A, Araim O, Sumpio B. Nicotine: a review of its role in atherosclerosis1 1No competing interests declared. Journal Of The American College Of Surgeons 2001, 193: 538-546. PMID: 11708512, DOI: 10.1016/s1072-7515(01)01059-6.Peer-Reviewed Original Research
1999
Localization of Atherosclerosis: Role of Hemodynamics
Frangos S, Gahtan V, Sumpio B. Localization of Atherosclerosis: Role of Hemodynamics. JAMA Surgery 1999, 134: 1142-1149. PMID: 10522862, DOI: 10.1001/archsurg.134.10.1142.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultArteriosclerosisEndothelium, VascularFemaleHemodynamicsHumansMaleRisk FactorsStress, MechanicalConceptsEndothelial cell structureCoronary arteryAortic archRisk factorsAbdominal aortaChronic diseasesVascular endotheliumCircumferential strainRole of hemodynamicsLesionsHemodynamic forcesCyclic circumferential strainMajor branchesSusceptible sitesAtherosclerosisArteryAortaHemodynamicsAtherogenesisEndotheliumDisease
1996
The pathobiology of diabetes mellitus: implications for surgeons.
Kamal K, Powell RJ, Sumpio BE. The pathobiology of diabetes mellitus: implications for surgeons. Journal Of The American College Of Surgeons 1996, 183: 271-89. PMID: 8784324.Peer-Reviewed Original Research
1991
Design and evaluation of a fiberoptic fluorescence guided laser recanalization system
Garrand T, Stetz M, O'Brien K, Gindi G, Sumpio B, Deckelbaum L. Design and evaluation of a fiberoptic fluorescence guided laser recanalization system. Lasers In Surgery And Medicine 1991, 11: 106-116. PMID: 2034008, DOI: 10.1002/lsm.1900110204.Peer-Reviewed Original ResearchMeSH KeywordsAngioplasty, LaserArteriosclerosisFemoral ArteryFiber Optic TechnologyHumansIn Vitro TechniquesLegSpectrometry, Fluorescence
1985
Results of Aortic Grafting in Occlusive vs Aneurysmal Disease
Sumpio B, Traquina D, Gusberg R. Results of Aortic Grafting in Occlusive vs Aneurysmal Disease. JAMA Surgery 1985, 120: 817-819. PMID: 4015373, DOI: 10.1001/archsurg.1985.01390310055012.Peer-Reviewed Original ResearchConceptsOcclusive diseaseAortic aneurysmAortic graftingOCC patientsSignificant intraoperative differenceSubsequent postoperative morbidityAtherosclerotic occlusive diseasePopulation of patientsDifferent patient groupsSignificant differencesRAA patientsAortic surgeryGraft surgeryPostoperative morbidityClamp timeSmoking historyDiabetes mellitusIntraoperative differencesPulmonary diseaseUrine outputFluid administrationAneurysmal diseaseAsymptomatic aneurysmsPatient groupRetrospective study