2003
Thrombospondin‐1‐induced vascular smooth muscle cell chemotaxis: The role of the type 3 repeat and carboxyl terminal domains
Lee T, Nesselroth SM, Olson ET, Esemuede N, Lawler J, Sumpio BE, Gahtan V. Thrombospondin‐1‐induced vascular smooth muscle cell chemotaxis: The role of the type 3 repeat and carboxyl terminal domains. Journal Of Cellular Biochemistry 2003, 89: 500-506. PMID: 12761883, DOI: 10.1002/jcb.10524.Peer-Reviewed Original ResearchConceptsVSMC chemotaxisThrombospondin-1Acute phase reactantsSmooth muscle cell chemotaxisVascular diseaseVascular smooth muscle cell chemotaxisPhase reactantsExtracellular signal-regulated kinases 1Microchemotaxis chamberSignal-regulated kinases 1Serum-free mediumCell chemotaxisMatricellular glycoproteinActivate ERKWestern immunoblottingVSMCsT-testP38 activationP38 pathwayERKFusion proteinT3ChemotaxisKinase 1P38 kinase
2001
The C-terminal domain of thrombospondin-1 induces vascular smooth muscle cell chemotaxis
Nesselroth S, Willis A, Fuse S, Olson E, Lawler J, Sumpio B, Gahtan V. The C-terminal domain of thrombospondin-1 induces vascular smooth muscle cell chemotaxis. Journal Of Vascular Surgery 2001, 33: 595-600. PMID: 11241132, DOI: 10.1067/mva.2001.112318.Peer-Reviewed Original ResearchConceptsVascular smooth muscle cellsVSMC chemotaxisThrombospondin-1VSMC migrationAortic vascular smooth muscle cellsTop wellsAcute phase reactantsBoyden chamber chemotaxisSmooth muscle cellsSmooth muscle cell chemotaxisVascular diseaseVascular lesionsVascular smooth muscle cell chemotaxisSerum-free mediumMuscle cellsTSP-1 moleculeCell chemotaxisChemotaxis assaysBottom wellsAntibodiesSelective inhibitionT-test