2005
In–Vitro Model for Evaluation of the Effects of Supercooling and Re-warming on Vascular Cells
Yiu W, Aruny J, Cheng S, Sumpio B. In–Vitro Model for Evaluation of the Effects of Supercooling and Re-warming on Vascular Cells. International Journal Of Angiology 2005, 14: 237-241. DOI: 10.1007/s00547-005-2055-5.Peer-Reviewed Original ResearchInitial technical success rateEndothelial cellsRe-warming phasePeripheral vascular diseaseTransluminal balloon angioplastyRate of restenosisTechnical success rateTUNEL-positive cellsSmooth muscle cellsBalloon angioplastyVascular diseaseEndothelial cell survivalMuscle cellsVascular cellsVitro modelVessel wallSuccess rateUnderlying mechanismRestenosisCell survivalCellsCellular responsesCritical roleAngioplastyCilostazol Inhibits Leukocyte Integrin Mac-1, Leading to a Potential Reduction in Restenosis After Coronary Stent Implantation
Sumpio BE, Aruny J. Cilostazol Inhibits Leukocyte Integrin Mac-1, Leading to a Potential Reduction in Restenosis After Coronary Stent Implantation. Perspectives In Vascular Surgery And Endovascular Therapy 2005, 17: 265-267. PMID: 16273169, DOI: 10.1177/153100350501700317.Peer-Reviewed Original ResearchCoronary stent implantationCoronary stentingStent implantationRate of restenosisLeukocyte integrin Mac-1Mechanism of restenosisP-selection expressionIntegrin Mac-1Cilostazol groupConsecutive patientsStent placementPhosphodiesterase IIIRestenosisMac-1Granule releasePatientsCilostazolStentingP-selectionLower ratesUpregulationPlateletsImplantationInhibitsTiclopidineIn–Vitro model for evaluation of the effects of supercooling and re-warming on vascular cells
Yiu W, Aruny J, Cheng S, Sumpio B. In–Vitro model for evaluation of the effects of supercooling and re-warming on vascular cells. International Journal Of Angiology 2005, 237-241. DOI: 10.1055/s-0031-1276516.Peer-Reviewed Original ResearchInitial technical success rateEndothelial cellsRe-warming phasePeripheral vascular diseaseTransluminal balloon angioplastyRate of restenosisTechnical success rateTUNEL-positive cellsSmooth muscle cellsBalloon angioplastyVascular diseaseEndothelial cell survivalMuscle cellsVascular cellsVitro modelVessel wallSuccess rateUnderlying mechanismRestenosisCell survivalCellsCellular responsesCritical roleAngioplasty
1993
Photoinhibition of smooth muscle cell migration: Potential therapy for restenosis
Deckelbaum L, Scott J, Stetz M, O'Brien K, Sumpio B, Madri J, Bell L. Photoinhibition of smooth muscle cell migration: Potential therapy for restenosis. Lasers In Surgery And Medicine 1993, 13: 4-11. PMID: 8426525, DOI: 10.1002/lsm.1900130104.Peer-Reviewed Original ResearchConceptsSmooth muscle cell migrationMuscle cell migrationLow energy light irradiationNeointima formationBroadband white lightCell migrationLight irradiationIncidence of restenosisLuminal cross-sectional areaSmooth muscle cell monolayersSmooth muscle cellsFibrointimal thickeningArterial injuryPotential therapyDaily radiant exposureRadiant exposureMuscle cellsThymidine incorporationRestenosisCross-sectional areaMigration of cellsCell proliferationCell monolayersMigration kineticsWhite light