2017
Overutilization of Cross-Sectional Imaging in the Lower Extremity Trauma Setting
Protack C, Wengerter B, Jean RA, Liu S, Mojibian H, Sumpio B, Dardik A, Maung AA, Erben Y. Overutilization of Cross-Sectional Imaging in the Lower Extremity Trauma Setting. International Journal Of Angiology 2017, 27: 023-028. PMID: 29483762, PMCID: PMC5825222, DOI: 10.1055/s-0037-1612622.Peer-Reviewed Original ResearchLower extremity vascular injuriesComputed tomography angiographyHard signsOperative explorationClinical suspicionTrauma patientsPrimary end pointTrauma Center ExperienceHigh clinical suspicionExtremity vascular injuriesCross-sectional imagingOperative interventionCenter experienceRetrospective reviewPhysical examinationVascular injuryTomography angiographyTrauma settingInitial screening toolCTA studiesPatientsEnd pointInjuryScreening toolInitial evaluation
2015
Venous Ulcer: Late Complication of a Traumatic Arteriovenous Fistula
Young CJ, Dardik A, Sumpio B, Indes J, Muhs B, Chaar C. Venous Ulcer: Late Complication of a Traumatic Arteriovenous Fistula. Annals Of Vascular Surgery 2015, 29: 836.e1-836.e3. PMID: 25725283, DOI: 10.1016/j.avsg.2014.11.020.Peer-Reviewed Case Reports and Technical NotesConceptsTraumatic AVFsLate complicationsArteriovenous fistula formationCongestive heart failureTraumatic arteriovenous fistulaDistal ischemiaHard signsVenous dilatationHeart failureInitial presentationOpen repairFistula formationVenous congestionArteriovenous fistulaVascular injuryCase reportAVFOperating roomComplicationsInjurySignsFistulaIschemiaUlcersPatients
2011
Traumatic Innominate Artery Pseudoaneurysm in the Setting of a Bovine Arch
Cordova AC, Bowen FW, Price LA, Dudrick SJ, Sumpio BE. Traumatic Innominate Artery Pseudoaneurysm in the Setting of a Bovine Arch. Annals Of Vascular Diseases 2011, 4: 252. PMID: 23555463, PMCID: PMC3595805, DOI: 10.3400/avd.cr.11.00028.Peer-Reviewed Original ResearchInnominate artery pseudoaneurysmArtery pseudoaneurysmBovine aortic archBlunt traumatic injuryChest X-rayAortic arch anatomyBovine archInnominate arteryCerebral perfusionHypothermic arrestClinical findingsAortic archArch anatomyCardiovascular bypassTraumatic injuryEEG monitoringComputerized tomographyInjuryPseudoaneurysmBypassCurrent literatureAnatomyArchAngiographyArtery
2007
Cryosurgery: A review
Yiu W, Basco M, Aruny J, Cheng S, Sumpio B. Cryosurgery: A review. International Journal Of Angiology 2007, 16: 1-6. PMID: 22477240, PMCID: PMC2732998, DOI: 10.1055/s-0031-1278235.Peer-Reviewed Original ResearchUse of cryotherapyDifferent clinical situationsUse of cryosurgeryPain controlSurgical resectionLow morbidityBronchial cancerProstate diseaseSafe techniqueTissue destructionLocalized lesionsClinical situationsCryosurgical techniquesLocal applicationDisease responseCryosurgeryClinical applicationFreeze injuryMorbidityResectionCryotherapyInjuryLesionsCancerDisease
2004
Vascular Smooth Muscle Cell Migration: Current Research and Clinical Implications
Willis AI, Pierre-Paul D, Sumpio BE, Gahtan V. Vascular Smooth Muscle Cell Migration: Current Research and Clinical Implications. Vascular And Endovascular Surgery 2004, 38: 11-23. PMID: 14760473, DOI: 10.1177/153857440403800102.Peer-Reviewed Original ResearchConceptsVSMC migrationVascular smooth muscle cell migrationSmooth muscle cell migrationPotential therapeutic approachMuscle cell migrationDiabetes mellitusEndothelial injuryTherapeutic approachesIntimal hyperplasiaClinical implicationsMajor causeDevelopment of strategiesInjuryCell migrationMultiple stimuliHypertensionMellitusHyperlipidemiaMorbiditySmokingHyperplasiaMortality
1993
Common pathway of endothelial-leukocyte interaction in shock, ischemia, and reperfusion
McMillen M, Huribal M, Sumpio B. Common pathway of endothelial-leukocyte interaction in shock, ischemia, and reperfusion. The American Journal Of Surgery 1993, 166: 557-562. PMID: 8238752, DOI: 10.1016/s0002-9610(05)81153-5.Peer-Reviewed Original ResearchConceptsBlood flowVascular endotheliumSignificant organ dysfunctionImpaired blood flowEndothelial-leukocyte interactionsRestoration of functionOrgan dysfunctionReperfusion injuryInflammatory cellsIschemia resultsInflammatory responseLeukocyte adherenceFurther injuryNeutrophil interactionsOxygen deliveryCurrent evidenceCellular injuryIschemiaEndothelial cellsInjuryCommon pathwayEndotheliumCurrent literatureCellular functionsAnaerobic mechanismsEndothelin-Stimulated Human Monocytes Produce Prostaglandin E2 but Not Leukotriene B4
McMillen M, Huribal M, Kumar R, Sumpio B. Endothelin-Stimulated Human Monocytes Produce Prostaglandin E2 but Not Leukotriene B4. Journal Of Surgical Research 1993, 54: 331-335. PMID: 8392650, DOI: 10.1006/jsre.1993.1053.Peer-Reviewed Original ResearchConceptsProstaglandin E2Pg/Human monocytesPost-traumatic immunosuppressionMonocytes/macrophagesBacterial lipopolysaccharide (LPS) stimulationEndothelin increaseM endothelinInterleukin-6Immune functionLeukotriene B4PGE2 productionVascular endotheliumEndothelinLipopolysaccharide (LPS) stimulationInjuryMonocytesAcid peptideE2B4HrActivationImmunosuppressionIschemiaMajor role
1991
Amelioration of renal ischemic injury by phosphocreatine
Rodriguez R, Stepke M, Maitz S, Cuono C, Sumpio B. Amelioration of renal ischemic injury by phosphocreatine. Journal Of Surgical Research 1991, 51: 271-274. PMID: 1921364, DOI: 10.1016/0022-4804(91)90106-v.Peer-Reviewed Original ResearchConceptsRenal ischemic injuryInitial ischemic insultPerfusion of kidneysKrebs-bicarbonate solutionMin of normothermicMM phosphocreatineRenal functionIschemic injuryKidney functionIschemic insultRenal arteryVivo ischemiaWarm ischemiaKrebs solutionKidneyPhosphocreatineAddition of phosphocreatineIschemiaSignificant improvementRegeneration of ATPGFRArteryNormothermicUreterInjury