2010
The critical role of hemodynamics in the development of cerebral vascular disease.
Nixon AM, Gunel M, Sumpio BE. The critical role of hemodynamics in the development of cerebral vascular disease. Journal Of Neurosurgery 2010, 112: 1240-53. PMID: 19943737, DOI: 10.3171/2009.10.jns09759.Peer-Reviewed Original ResearchConceptsCerebral vascular diseaseVascular diseaseUnique hemodynamic conditionsExtracranial atherosclerosisArtery diseaseIntracranial atherosclerosisIntracranial saccular aneurysmsTreatment optionsVascular disordersHemodynamic parametersAneurysm formationSaccular aneurysmHemodynamic conditionsNormal levelsVascular biologyDiseaseMultiple studiesMore studiesPatient-specific dataAtherosclerosisHemodynamicsMagnitude of WSSRiskLow wall shear stressDisorders
1999
Localization of Atherosclerosis: Role of Hemodynamics
Frangos S, Gahtan V, Sumpio B. Localization of Atherosclerosis: Role of Hemodynamics. JAMA Surgery 1999, 134: 1142-1149. PMID: 10522862, DOI: 10.1001/archsurg.134.10.1142.Peer-Reviewed Original ResearchConceptsEndothelial cell structureCoronary arteryAortic archRisk factorsAbdominal aortaChronic diseasesVascular endotheliumCircumferential strainRole of hemodynamicsLesionsHemodynamic forcesCyclic circumferential strainMajor branchesSusceptible sitesAtherosclerosisArteryAortaHemodynamicsAtherogenesisEndotheliumDisease