2011
Varying Effects of Hemodynamic Forces on Tissue Factor RNA Expression in Human Endothelial Cells
Abe R, Yamashita N, Rochier A, Nixon A, Abe R, Madri JA, Sumpio BE. Varying Effects of Hemodynamic Forces on Tissue Factor RNA Expression in Human Endothelial Cells. Journal Of Surgical Research 2011, 170: 150-156. PMID: 21592524, DOI: 10.1016/j.jss.2011.04.002.Peer-Reviewed Original ResearchConceptsLaminar flowOscillatory flowCyclic strainUnidirectional laminar flowUniform laminar flowMechanical stressDisturbed flowTF RNA expressionHuman umbilical vein endothelial cellsFlowStatic controlHigh TF expressionTF expressionForceMechanical forcesEndothelial cellsRNA expressionSustained amplification
2005
Artificial blood vessel: The Holy Grail of peripheral vascular surgery
Kakisis JD, Liapis CD, Breuer C, Sumpio BE. Artificial blood vessel: The Holy Grail of peripheral vascular surgery. Journal Of Vascular Surgery 2005, 41: 349-354. PMID: 15768021, DOI: 10.1016/j.jvs.2004.12.026.Peer-Reviewed Original ResearchConceptsVascular tissue engineeringArtificial vesselsIdeal vascular graftMechanical propertiesArtificial blood vesselsTissue engineeringBiodegradable polymersNative tissuePulsatile flowSmall intestine submucosaVascular graftsVivo environmentBioreactorVascular cellsPeripheral vascular surgeryInitial experimentsEngineeringPolymersFlow