2005
Nicotine induces mitogen-activated protein kinase dependent vascular smooth muscle cell migration
Di Luozzo G, Pradhan S, Dhadwal AK, Chen A, Ueno H, Sumpio BE. Nicotine induces mitogen-activated protein kinase dependent vascular smooth muscle cell migration. Atherosclerosis 2005, 178: 271-277. PMID: 15694934, DOI: 10.1016/j.atherosclerosis.2004.09.017.Peer-Reviewed Original ResearchConceptsVascular smooth muscle cell migrationSmooth muscle cell migrationMuscle cell migrationInhibitors of p38VSMC migrationMitogen-activated protein kinaseEndothelial cellsDevelopment of atherosclerosisEffects of nicotineCell migrationWestern blotting methodInjury modelVascular endotheliumCigarette smokeBoyden chamber chemotaxis assaysAortic VSMCsChemotactic effectMAPKs p38NicotineChemoattractant moleculesChemotaxis assaysCellular mechanismsUltrastructural changesVSMCP44/42 activation
2001
The C-terminal domain of thrombospondin-1 induces vascular smooth muscle cell chemotaxis
Nesselroth S, Willis A, Fuse S, Olson E, Lawler J, Sumpio B, Gahtan V. The C-terminal domain of thrombospondin-1 induces vascular smooth muscle cell chemotaxis. Journal Of Vascular Surgery 2001, 33: 595-600. PMID: 11241132, DOI: 10.1067/mva.2001.112318.Peer-Reviewed Original ResearchConceptsVascular smooth muscle cellsVSMC chemotaxisThrombospondin-1VSMC migrationAortic vascular smooth muscle cellsTop wellsAcute phase reactantsBoyden chamber chemotaxisSmooth muscle cellsSmooth muscle cell chemotaxisVascular diseaseVascular lesionsVascular smooth muscle cell chemotaxisSerum-free mediumMuscle cellsTSP-1 moleculeCell chemotaxisChemotaxis assaysBottom wellsAntibodiesSelective inhibitionT-test