2000
Tissue Plasminogen Activator: Biological and Physiological Relevance for Vascular Surgeons
Chang R, Kamal K, Sumpio B. Tissue Plasminogen Activator: Biological and Physiological Relevance for Vascular Surgeons. 2000, 1315-1323. DOI: 10.1007/978-1-4612-1190-7_103.Peer-Reviewed Original ResearchTissue-type plasminogen activatorThrombolytic therapyDeep venous thrombosisOcclusive vascular diseaseEfficacy of treatmentCerebrovascular accidentPulmonary embolismVenous thrombosisClinical outcomesMyocardial infarctionVascular diseaseVascular surgeonsHuman trialsEffective treatmentThrombolytic agentsPlasminogen activatorTherapyPhysiological relevanceTreatmentEndogenous propertiesEmbolismInfarctionThrombosisPatientsAgents
1989
The influence of perfusate viscosity, RBC deformability and drag on the function of an isolated perfused rat kidney
Sumpio B, Upchurch G, Johnson G. The influence of perfusate viscosity, RBC deformability and drag on the function of an isolated perfused rat kidney. Journal Of Surgical Research 1989, 46: 4-8. PMID: 2915534, DOI: 10.1016/0022-4804(89)90174-1.Peer-Reviewed Original ResearchConceptsRenal functionMean renal arterial pressureRat kidneyKrebs-HCO3 bufferRenal arterial pressureReabsorption of sodiumArterial pressureUrine flowOrgan functionClinical interestHCO3- bufferPerfusate solutionHematocritBlood rheologyFunctional parametersPerfusate viscosityRBC deformabilityKidneyPerfusateDegrees CRBCsDrag-reducing agentsGFRCreatinineAgents