2023
Spontaneous vesicoureteral reflux resolution curves based on ureteral diameter ratio
Arlen A, Leong T, Kirsch A, Cooper C. Spontaneous vesicoureteral reflux resolution curves based on ureteral diameter ratio. Journal Of Pediatric Urology 2023, 19: 468.e1-468.e6. PMID: 37188603, DOI: 10.1016/j.jpurol.2023.04.028.Peer-Reviewed Original ResearchConceptsUreteral diameter ratioUrinary tract infectionPrimary vesicoureteral refluxVesicoureteral refluxSpontaneous resolutionRisk groupsBreakthrough febrile urinary tract infectionDistal ureteral diameter ratioFebrile urinary tract infectionLargest ureteral diameterObjective prognostic informationGrade of refluxHigh-risk patientsLow-risk patientsHigh-risk groupLow-risk groupLow-risk childrenVUR resolutionPrimary refluxProphylactic antibioticsVUR gradeConservative managementPersistent refluxRisk patientsTract infections
2020
Urinary Tract Infection USA
Arlen A, Cooper C. Urinary Tract Infection USA. 2020, 1-5. DOI: 10.1007/978-3-030-24730-0_1.Peer-Reviewed Original ResearchChapter 9 Ureteropyelostomy and ureteroureterostomy
Cooper C, Arlen A. Chapter 9 Ureteropyelostomy and ureteroureterostomy. 2020, 109-116. DOI: 10.1016/b978-0-12-817888-1.00009-4.Peer-Reviewed Original ResearchUrinary tract infectionVesicoureteral refluxClinical courseUreteral duplicationLower pole vesicoureteral refluxMesonephric ductChild's clinical courseLower pole systemPresence of refluxMaintenance of continenceUpper pole moietyComplete ureteral duplicationUreteric budRenal functionTract infectionsSurgical morbidityWeigert-Meyer lawUpper poleUreterocele punctureLower poleReconstructive alternativeUreteroceleAbnormal branchingRefluxParental preferences
2018
Impact of continuous low-dose antibiotic prophylaxis on growth in children with vesicoureteral reflux
Guidos P, Arlen A, Leong T, Bonnett M, Cooper C. Impact of continuous low-dose antibiotic prophylaxis on growth in children with vesicoureteral reflux. Journal Of Pediatric Urology 2018, 14: 325.e1-325.e7. PMID: 30181099, DOI: 10.1016/j.jpurol.2018.07.007.Peer-Reviewed Original ResearchConceptsContinuous antibiotic prophylaxisBody mass indexPrior treatment coursesPrior antibiotic useAntibiotic prophylaxisVesicoureteral refluxBMI percentileYears of ageTreatment courseMass indexAntibiotic useHeight percentilesContinuous low-dose antibiotic prophylaxisUse of CAPLow-dose antibiotic prophylaxisPrior antibiotic usageSignificant BMI increaseMainstay of treatmentUrinary tract infectionPrimary vesicoureteral refluxSignificant increaseUse of antibioticsBreakthrough infectionsEffects of antibioticsTract infections
2017
Endoscopic Treatment of Vesicoureteral Reflux
Arlen A, Kirsch A. Endoscopic Treatment of Vesicoureteral Reflux. Current Bladder Dysfunction Reports 2017, 12: 217-224. DOI: 10.1007/s11884-017-0431-6.Peer-Reviewed Original ResearchPrimary vesicoureteral refluxVesicoureteral refluxRenal scarringClinical courseRecurrent febrile urinary tract infectionsFebrile urinary tract infectionLaparoscopic/robotic approachChild's clinical courseContinuous antibiotic prophylaxisUltimate success rateUrinary tract infectionMajority of childrenInvasive surgical proceduresAntibiotic prophylaxisEfficacy rateEndoscopic injectionPersistent refluxReflux gradeTract infectionsEndoscopic correctionEndoscopic treatmentSurgical repairRecurrent infectionsSurgical interventionSurgical correctionRole of body mass index in school-aged children with lower urinary tract dysfunction: Does weight classification predict treatment outcome?
Arlen AM, Cooper CS, Leong T. Role of body mass index in school-aged children with lower urinary tract dysfunction: Does weight classification predict treatment outcome? Journal Of Pediatric Urology 2017, 13: 454.e1-454.e5. PMID: 28483466, DOI: 10.1016/j.jpurol.2017.03.033.Peer-Reviewed Original ResearchConceptsBody mass indexBladder-bowel dysfunctionLower urinary tract dysfunctionUrinary tract dysfunctionUrinary tract infectionSchool-aged childrenTreatment outcomesTreatment responseLUT dysfunctionTract dysfunctionTract infectionsTreatment failureMass indexElevated body mass indexLower urinary tract symptomsDetrusor-sphincter dyssynergiaUrinary tract symptomsAdditional treatment modalitiesComplete treatment responseMajor health concernBowel programPsychologic comorbiditiesSphincter dyssynergiaUrology referralTract symptomsHospital-acquired Urinary Tract Infections in Neonatal ICU Patients: Is Voiding Cystourethrogram Necessary?
Asghar AM, Leong T, Cooper CS, Arlen AM. Hospital-acquired Urinary Tract Infections in Neonatal ICU Patients: Is Voiding Cystourethrogram Necessary? Urology 2017, 105: 163-166. PMID: 28408336, DOI: 10.1016/j.urology.2017.04.002.Peer-Reviewed Original ResearchConceptsUrinary tract infectionHospital-acquired urinary tract infectionsEffect of ageTract infectionsNICU patientsVesicoureteral refluxUltrasound resultsNeonatal intensive care unit patientsIntensive care unit patientsNeonatal ICU patientsMean gestational ageCare unit patientsMean of ageCoagulase-negative staphylococciNICU admissionRetroperitoneal ultrasoundUTI increasesPatient characteristicsUnit patientsICU patientsGestational ageImaging findingsUrine cultureRadiographic findingsAbnormal ultrasoundMP61-09 DISTAL URETERAL DIAMETER RATIO IS AN INDEPENDENT RISK FACTOR FOR BREAKTHROUGH FEBRILE URINARY TRACT INFECTION
Arlen A, Alexander S, Guidos P, Leong T, Cooper C. MP61-09 DISTAL URETERAL DIAMETER RATIO IS AN INDEPENDENT RISK FACTOR FOR BREAKTHROUGH FEBRILE URINARY TRACT INFECTION. Journal Of Urology 2017, 197: e802. DOI: 10.1016/j.juro.2017.02.1867.Peer-Reviewed Original Research
2016
Delayed upper tract drainage on voiding cystourethrogram may not be associated with increased risk of urinary tract infection in children with vesicoureteral reflux
Garcia-Roig M, Arlen AM, Huang JH, Filimon E, Leong T, Kirsch AJ. Delayed upper tract drainage on voiding cystourethrogram may not be associated with increased risk of urinary tract infection in children with vesicoureteral reflux. Journal Of Pediatric Urology 2016, 12: 312.e1-312.e6. PMID: 27492248, DOI: 10.1016/j.jpurol.2016.04.056.Peer-Reviewed Original ResearchConceptsUpper tract drainageCulture-proven UTIsVesicoureteral refluxUTI ratesVUR gradeUTI riskRisk factorsHigh inter-observer correlationSetting of obstructionUTI risk factorsUrinary tract infectionPrimary vesicoureteral refluxPredictors of infectionAvailable prognostic informationSignificant predictorsYears of ageEndoscopic VUR treatmentHydrodistention gradeInter-observer agreementRecurrent UTIUTI incidenceVUR timingEndoscopic findingsInter-observer correlationTract infectionsVesicoureteral Reflux
Arlen A, Cooper C. Vesicoureteral Reflux. 2016, 95-113. DOI: 10.1007/978-3-319-29219-9_6.Peer-Reviewed Original ResearchUrinary tract infectionVesicoureteral refluxSurgical correctionRecurrent febrile urinary tract infectionsFebrile urinary tract infectionLaparoscopic/robotic approachContinuous antibiotic prophylaxisMorbidity of treatmentRenal cortical scarringUpper urinary tractAntibiotic prophylaxisCortical scarringRenal injuryTract infectionsUrinary tractSpontaneous resolutionFurther infectionRobotic approachChildren's riskRetrograde flowInfectionRefluxParental preferencesRiskProphylaxisComputer model predicting breakthrough febrile urinary tract infection in children with primary vesicoureteral reflux
Arlen AM, Alexander SE, Wald M, Cooper CS. Computer model predicting breakthrough febrile urinary tract infection in children with primary vesicoureteral reflux. Journal Of Pediatric Urology 2016, 12: 288.e1-288.e5. PMID: 27072485, DOI: 10.1016/j.jpurol.2016.03.005.Peer-Reviewed Original ResearchConceptsBreakthrough febrile urinary tract infectionFebrile urinary tract infectionPrimary vesicoureteral refluxBladder-bowel dysfunctionOnset of VURUrinary tract infectionVesicoureteral refluxLow bladder volumesBladder volumeUTI historyTract infectionsPrognostic calculatorSpontaneous resolutionRecurrent febrile urinary tract infectionsCorrect vesicoureteral refluxRecurrent febrile infectionsRenal parenchymal scarringIndividual child's riskCharacteristic curve areaParenchymal scarringVCUG findingsRenal scarringPatient demographicsVUR gradeFebrile infections
2015
Complications of antireflux surgery
Arlen A, Caldamone A, Kirsch A. Complications of antireflux surgery. 2015, 87-95. DOI: 10.1002/9781118473382.ch10.Peer-Reviewed Original ResearchFebrile urinary tract infectionUrinary tract infectionVesicoureteral refluxPersistent refluxTract infectionsRecurrent febrile urinary tract infectionsContinuous antibiotic prophylaxisUpper urinary tractAntibiotic prophylaxisRecurrent pyelonephritisAntireflux surgeryRenal scarringEndoscopic treatmentSurgical managementUreteral reimplantationBladder pathologySurgical interventionUreteral obstructionUrinary tractOutpatient procedureSurgical correctionUrologic diagnosisHigh success rateOptimal managementRobotic approach
2014
Bladder Volume at Onset of Vesicoureteral Reflux is an Independent Risk Factor for Breakthrough Febrile Urinary Tract Infection
Alexander S, Arlen A, Storm D, Kieran K, Cooper C. Bladder Volume at Onset of Vesicoureteral Reflux is an Independent Risk Factor for Breakthrough Febrile Urinary Tract Infection. Journal Of Urology 2014, 193: 1342-1346. PMID: 25305355, DOI: 10.1016/j.juro.2014.10.002.Peer-Reviewed Original ResearchConceptsBreakthrough febrile urinary tract infectionFebrile urinary tract infectionUrinary tract infectionOnset of refluxBladder-bowel dysfunctionRisk of pyelonephritisTract infectionsVesicoureteral refluxBladder volumeReflux gradeRecurrent febrile urinary tract infectionsMedian bladder volumeIndependent risk factorAdditional prognostic informationIdentification of childrenDuration of exposureReflux onsetBladder capacityMedian followupSD agePrognostic informationRisk factorsMultivariate analysisClinical decisionInfection
2013
Endoscopic Injection Techniques for Vesicoureteral Reflux
Arlen A, Scherz H, Kirsch A. Endoscopic Injection Techniques for Vesicoureteral Reflux. 2013, 207-216. DOI: 10.1007/978-1-4471-5394-8_22.Peer-Reviewed Original ResearchVesicoureteral refluxRecurrent febrile urinary tract infectionsFebrile urinary tract infectionLaparoscopic/robotic approachContinuous antibiotic prophylaxisUrinary tract infectionUpper urinary tractEndoscopic injection techniqueAntibiotic prophylaxisUreteral hydrodistentionRenal scarringPersistent refluxTract infectionsEndoscopic treatmentUreteral reimplantationSurgical interventionTransurethral injectionUrinary tractOutpatient procedureSubmucosal injectionSurgical correctionUreteral orificeUrologic diagnosisDecreased morbidityIntraluminal injection
2010
Urinary Tract Infection: USA
Arlen A, Cooper C. Urinary Tract Infection: USA. 2010, 3-7. DOI: 10.1007/978-1-84996-366-4_1.Peer-Reviewed Original Research