2014
Ischemic Outcomes After Coronary Intervention of Calcified Vessels in Acute Coronary Syndromes Pooled Analysis From the HORIZONS-AMI (Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction) and ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) Trials
Généreux P, Madhavan MV, Mintz GS, Maehara A, Palmerini T, LaSalle L, Xu K, McAndrew T, Kirtane A, Lansky AJ, Brener SJ, Mehran R, Stone GW. Ischemic Outcomes After Coronary Intervention of Calcified Vessels in Acute Coronary Syndromes Pooled Analysis From the HORIZONS-AMI (Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction) and ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) Trials. Journal Of The American College Of Cardiology 2014, 63: 1845-1854. PMID: 24561145, DOI: 10.1016/j.jacc.2014.01.034.Peer-Reviewed Original ResearchConceptsST-segment elevation myocardial infarctionSevere target lesion calcificationAcute coronary syndromePercutaneous coronary interventionTarget lesion calcificationTarget lesion revascularizationElevation acute coronary syndromeDefinite stent thrombosisLesion calcificationStent thrombosisHORIZONS-AMICoronary syndromeCoronary interventionCoronary calcificationST-segment elevation acute coronary syndromeSegment elevation acute coronary syndromesIndependent angiographic core laboratoryStable coronary artery diseaseSevere lesion calcificationOne-year outcomesElevation myocardial infarctionCoronary artery diseaseAngiographic core laboratoryACUITY trialIschemic outcomes
2012
Implications of pre-procedural TIMI flow in patients with non ST-segment elevation acute coronary syndromes undergoing percutaneous coronary revascularization: Insights from the ACUITY trial
De Luca G, Brener SJ, Mehran R, Lansky AJ, McLaurin BT, Cox DA, Cristea E, Fahy M, Stone GW. Implications of pre-procedural TIMI flow in patients with non ST-segment elevation acute coronary syndromes undergoing percutaneous coronary revascularization: Insights from the ACUITY trial. International Journal Of Cardiology 2012, 167: 727-732. PMID: 22464479, DOI: 10.1016/j.ijcard.2012.03.058.Peer-Reviewed Original ResearchConceptsST-segment elevation myocardial infarctionPercutaneous coronary interventionAcute coronary syndromeHigh-risk patientsTIMI flowACUITY trialCoronary syndromeMyocardial infarctionNon-ST segment elevation acute coronary syndromesST-segment elevation acute coronary syndromePost-PCI TIMI 3 flowElevation acute coronary syndromeIndependent angiographic core laboratoryPre-procedural TIMI flowBaseline TIMI flowPre-PCI TIMIPreprocedural TIMI flowTIMI 3 flowEarly invasive managementElevation myocardial infarctionNegative prognostic impactPercutaneous coronary revascularizationAngiographic core laboratoryReduced ThrombolysisTIMI 0/1
2006
Racial Differences Among High-Risk Patients Presenting With Non–ST-Segment Elevation Acute Coronary Syndromes (Results from the SYNERGY Trial)††Disclosure: Drs. Mahaffey, Cohen, Newby, Ferguson, and Califf have received honoria for speaking from sanofi-aventis. Drs. Mahaffey, Ferguson, and Califf have acted as consultants for sanofi-aventis. Drs. Echols, Velazquez, Santos, and Gurfinkel have no financial relationships to disclose.
Echols MR, Mahaffey KW, Banerjee A, Pieper KS, Stebbins A, Lansky A, Cohen MG, Velazquez E, Santos R, Newby LK, Gurfinkel EP, Biasucci L, Ferguson JJ, Califf RM. Racial Differences Among High-Risk Patients Presenting With Non–ST-Segment Elevation Acute Coronary Syndromes (Results from the SYNERGY Trial)††Disclosure: Drs. Mahaffey, Cohen, Newby, Ferguson, and Califf have received honoria for speaking from sanofi-aventis. Drs. Mahaffey, Ferguson, and Califf have acted as consultants for sanofi-aventis. Drs. Echols, Velazquez, Santos, and Gurfinkel have no financial relationships to disclose. The American Journal Of Cardiology 2006, 99: 315-321. PMID: 17261389, DOI: 10.1016/j.amjcard.2006.08.031.Peer-Reviewed Original ResearchConceptsAcute coronary syndromeAfrican American patientsMyocardial infarctionWhite patientsCoronary syndromeSegment elevation (NSTE) ACSST-segment elevation acute coronary syndromeElevation acute coronary syndromeBaseline clinical characteristicsFrequency of hypertensionNonfatal myocardial infarctionThirty-day deathCoronary artery bypassHigh-risk patientsOutcomes of patientsSanofi-AventisPercutaneous coronary interventionUse of angiographyNorth American patientsRacial differencesAfrican AmericansSYNERGY trialArtery bypassClinical characteristicsCoronary intervention