2011
Radial access in patients with ST-segment elevation myocardial infarction undergoing primary angioplasty in acute myocardial infarction: the HORIZONS-AMI trial.
Généreux P, Mehran R, Palmerini T, Caixeta A, Kirtane AJ, Lansky AJ, Brodie BR, Witzenbichler B, Mockel M, Guagliumi G, Peruga JZ, Dudek D, Fahy MP, Dangas G, Stone GW. Radial access in patients with ST-segment elevation myocardial infarction undergoing primary angioplasty in acute myocardial infarction: the HORIZONS-AMI trial. EuroIntervention 2011, 7: 905-16. PMID: 22157475, DOI: 10.4244/eijv7i8a144.Peer-Reviewed Original ResearchConceptsST-segment elevation myocardial infarctionPrimary percutaneous coronary interventionPrimary PCIHORIZONS-AMI trialElevation myocardial infarctionMajor bleedingMyocardial infarctionTF approachMajor adverse cardiovascular eventsNet adverse clinical eventsAdverse cardiovascular eventsEvent-free survivalAdverse clinical eventsPercutaneous coronary interventionImproved clinical outcomesAcute myocardial infarctionOne-year ratesRate of deathPaucity of dataComposite deathHORIZONS-AMICardiovascular eventsPrimary angioplastyAnticoagulation regimensCoronary intervention
2010
Impact of Delay to Angioplasty in Patients With Acute Coronary Syndromes Undergoing Invasive Management Analysis From the ACUITY (Acute Catheterization and Urgent Intervention Triage strategY) Trial
Sorajja P, Gersh BJ, Cox DA, McLaughlin MG, Zimetbaum P, Costantini C, Stuckey T, Tcheng JE, Mehran R, Lansky AJ, Grines CL, Stone GW. Impact of Delay to Angioplasty in Patients With Acute Coronary Syndromes Undergoing Invasive Management Analysis From the ACUITY (Acute Catheterization and Urgent Intervention Triage strategY) Trial. Journal Of The American College Of Cardiology 2010, 55: 1416-1424. PMID: 20359590, DOI: 10.1016/j.jacc.2009.11.063.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionAcute coronary syndromeCoronary syndromeACUITY trialNSTE-ACSCoronary interventionIndependent predictorsClinical presentationMyocardial infarctionSegment elevation acute coronary syndromesTiming of PCIElevation acute coronary syndromeAdverse ischemic outcomesInvasive management strategyNSTE-ACS patientsHigh-risk featuresSignificant independent predictorsPaucity of dataComposite ischemiaIschemic outcomesUrgent angiographyImpact of delayLate mortalityMultivariable analysisOutcome analysis