2001
Comparison of Tl-201 with Tc-99m–labeled myocardial perfusion agents: Technical, physiologic, and clinical issues
Kailasnath P, Sinusas A. Comparison of Tl-201 with Tc-99m–labeled myocardial perfusion agents: Technical, physiologic, and clinical issues. Journal Of Nuclear Cardiology 2001, 8: 482-498. PMID: 11481571, DOI: 10.1067/mnc.2001.115078.Peer-Reviewed Original Research
2000
Assessment of left ventricular ejection fraction with quantitative gated SPECT: Accuracy and correlation with first-pass radionuclide angiography
Vallejo E, Dione D, Sinusas A, Wackers F. Assessment of left ventricular ejection fraction with quantitative gated SPECT: Accuracy and correlation with first-pass radionuclide angiography. Journal Of Nuclear Cardiology 2000, 7: 461-470. PMID: 11083195, DOI: 10.1067/mnc.2000.107820.Peer-Reviewed Original ResearchConceptsVentricular ejection fractionEjection fractionPatient studiesLeft ventricular ejection fractionExtracardiac activityFirst-pass radionuclide angiographyLarger end-diastolic volumeStress-induced ischemiaEnd-diastolic volumeQuantitative gated SPECTSingle photon emissionAbnormal LVEFNormal LVEFRadionuclide angiographyDiastolic volumeLVEFPerfusion defectsLVEF valuesSame patientHeart sizeLeft ventricleGated SPECTSPECT studiesQGSMean rest
1998
Exercise testing with myocardial perfusion imaging in patients with normal baseline electrocardiograms: Cost savings with a stepwise diagnostic strategy
Mattera J, Arain S, Sinusas A, Finta L, Wackers F. Exercise testing with myocardial perfusion imaging in patients with normal baseline electrocardiograms: Cost savings with a stepwise diagnostic strategy. Journal Of Nuclear Cardiology 1998, 5: 498-506. PMID: 9796897, DOI: 10.1016/s1071-3581(98)90181-7.Peer-Reviewed Original ResearchConceptsExercise myocardial perfusion imagingCoronary artery diseaseNormal exercise electrocardiogramMyocardial perfusion imagingNormal myocardial perfusion imagingNormal resting electrocardiogramsExercise electrocardiogramExercise testingArtery diseaseIntermediate likelihoodResting electrocardiogramsAbnormal myocardial perfusion imagingDiagnostic strategiesAbnormal exercise electrocardiogramGroup 3 patientsHard cardiac eventsNonfatal myocardial infarctionNormal baseline electrocardiogramSubsequent coronary revascularizationIncremental diagnostic informationDiagnostic testing strategiesCoronary revascularizationCardiac eventsUnstable anginaConsecutive patientsExperimental evaluation of radiotracers: Role of intact biological models
Sinusas A. Experimental evaluation of radiotracers: Role of intact biological models. Journal Of Nuclear Cardiology 1998, 5: 167-183. PMID: 9588669, DOI: 10.1016/s1071-3581(98)90200-8.Peer-Reviewed Original Research
1993
Myocardial risk area defined by technetium-99m sestamibi imaging during percutaneous transluminal coronary angioplasty: Comparison with coronary angiography
Haronian H, Remetz M, Sinusas A, Baron J, Miller H, Cleman M, Zaret B, Wackers F. Myocardial risk area defined by technetium-99m sestamibi imaging during percutaneous transluminal coronary angioplasty: Comparison with coronary angiography. Journal Of The American College Of Cardiology 1993, 22: 1033-1043. PMID: 8409038, DOI: 10.1016/0735-1097(93)90413-u.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAngioplasty, Balloon, CoronaryClinical ProtocolsCollateral CirculationCoronary AngiographyCoronary DiseaseEvaluation Studies as TopicFemaleHumansMaleMiddle AgedMyocardial InfarctionObserver VariationPredictive Value of TestsPrognosisReproducibility of ResultsRisk FactorsSeverity of Illness IndexTechnetium Tc 99m SestamibiTomography, Emission-Computed, Single-PhotonConceptsMyocardial risk areaCoronary angiographyCoronary angioplastyQuantitative myocardial perfusionMyocardial perfusionMyocardial areaPercutaneous transluminal coronary angioplastyAngiographic risk scoresSmall risk areasTransluminal coronary angioplastyCoronary artery diseaseCoronary artery stenosisInitial myocardial uptakeAngioplasty balloon inflationArtery diseaseLeft anteriorNonperfused areaArtery stenosisCoronary anatomyCoronary arteryBalloon inflationPatient managementMyocardial uptakeRisk scoreAngioplasty
1990
Experimental studies of the physiologic properties of technetium-99m isonitriles
Beller G, Sinusas A. Experimental studies of the physiologic properties of technetium-99m isonitriles. The American Journal Of Cardiology 1990, 66: e5-e8. PMID: 2145747, DOI: 10.1016/0002-9149(90)90605-z.Peer-Reviewed Original ResearchCardiac imaging with technetium 99m-labeled isonitriles
Sinusas A, Beller G, Watson D. Cardiac imaging with technetium 99m-labeled isonitriles. Journal Of Thoracic Imaging 1990, 5: 20-30. PMID: 2194038, DOI: 10.1097/00005382-199007000-00006.Peer-Reviewed Original ResearchConceptsMyocardial perfusionMyocardial injuryMyocardial ischemiaNoninvasive meansAcute coronary occlusionIschemic myocardial injuryIrreversible myocardial injurySingle-day protocolFull clinical implicationsFurther clinical studiesReversible myocardial ischemiaMyocardial dysfunctionMyocardial salvageCoronary occlusionClinical studiesMyocardial imaging agentClinical experienceTherapeutic interventionsInitial experienceClinical implicationsPerfusionIschemiaImaging agentInjuryRadiotracer
1989
Effect of ischemia and postischemic dysfunction on myocardial uptake of technetium-99m-labeled methoxyisobutyl isonitrile and thallium-201
Sinusas A, Watson D, Cannon J, Beller G. Effect of ischemia and postischemic dysfunction on myocardial uptake of technetium-99m-labeled methoxyisobutyl isonitrile and thallium-201. Journal Of The American College Of Cardiology 1989, 14: 1785-1793. PMID: 2584570, DOI: 10.1016/0735-1097(89)90034-x.Peer-Reviewed Original ResearchConceptsLow coronary flowThallium-201Postischemic dysfunctionMyocardial uptakeArtery occlusionMethoxyisobutyl isonitrileEndocardial flowCoronary flowGroup II dogsTwo-dimensional echocardiographyEffects of ischemiaRegional blood flowOpen-chest canine modelMyocardial perfusion agentEpicardial segmentsRadionuclide injectionBlood flowEndocardial segmentsRegional dysfunctionIschemic regionLeft ventricleCanine modelDysfunctionGroup IPerfusion agent
1984
Pathoanatomic correlates of regional left ventricular wall motion assessed by equilibrium radionuclide angiocardiography: A postmortem correlation
Sinusas A, Hardin N, Clements J, Wackers F. Pathoanatomic correlates of regional left ventricular wall motion assessed by equilibrium radionuclide angiocardiography: A postmortem correlation. The American Journal Of Cardiology 1984, 54: 975-981. PMID: 6496360, DOI: 10.1016/s0002-9149(84)80128-9.Peer-Reviewed Original ResearchConceptsAbnormal regional wall motionRegional wall motionPostmortem findingsPathoanatomic correlatesEquilibrium radionuclideLeft bundle branch blockNormal regional wall motionGross myocardial lesionsLeft ventricular wall motionBundle branch blockLeft ventricular segmentsRegional left ventricular wall motionVentricular wall motionFalse-negative segmentsCoronary arterySevere stenosisMyocardial infarctionNontransmural infarctionBranch blockVentricular segmentsWall motionMyocardial lesionsPatientsPredictive valueAbnormal segments