Salil Garg, MD, PhD
Assistant Professor of Laboratory MedicineCards
About
Research
Publications
2024
The dynamics of hematopoiesis over the human lifespan
Li H, Côté P, Kuoch M, Ezike J, Frenis K, Afanassiev A, Greenstreet L, Tanaka-Yano M, Tarantino G, Zhang S, Whangbo J, Butty V, Moiso E, Falchetti M, Lu K, Connelly G, Morris V, Wang D, Chen A, Bianchi G, Daley G, Garg S, Liu D, Chou S, Regev A, Lummertz da Rocha E, Schiebinger G, Rowe R. The dynamics of hematopoiesis over the human lifespan. Nature Methods 2024, 22: 422-434. PMID: 39639169, PMCID: PMC11908799, DOI: 10.1038/s41592-024-02495-0.Peer-Reviewed Original Research
2022
Transcription factor antagonism regulates heterogeneity in embryonic stem cell states
Hu S, Metcalf E, Mahat D, Chan L, Sohal N, Chakraborty M, Hamilton M, Singh A, Singh A, Lees J, Sharp P, Garg S. Transcription factor antagonism regulates heterogeneity in embryonic stem cell states. Molecular Cell 2022, 82: 4410-4427.e12. PMID: 36356583, PMCID: PMC9722640, DOI: 10.1016/j.molcel.2022.10.022.Peer-Reviewed Original ResearchDevelopmental Deconvolution for Classification of Cancer Origin
Moiso E, Farahani A, Marble H, Hendricks A, Mildrum S, Levine S, Lennerz J, Garg S. Developmental Deconvolution for Classification of Cancer Origin. Cancer Discovery 2022, 12: 2566-2585. PMID: 36041084, PMCID: PMC9627133, DOI: 10.1158/2159-8290.cd-21-1443.Peer-Reviewed Original Research
2021
Acquired resistance to PRMT5 inhibition induces concomitant collateral sensitivity to paclitaxel
Mueller H, Fowler C, Dalin S, Moiso E, Udomlumleart T, Garg S, Hemann M, Lees J. Acquired resistance to PRMT5 inhibition induces concomitant collateral sensitivity to paclitaxel. Proceedings Of The National Academy Of Sciences Of The United States Of America 2021, 118: e2024055118. PMID: 34408017, PMCID: PMC8403834, DOI: 10.1073/pnas.2024055118.Peer-Reviewed Original ResearchLineages of embryonic stem cells show non-Markovian state transitions
Udomlumleart T, Hu S, Garg S. Lineages of embryonic stem cells show non-Markovian state transitions. IScience 2021, 24: 102879. PMID: 34401663, PMCID: PMC8353490, DOI: 10.1016/j.isci.2021.102879.Peer-Reviewed Original ResearchEnhancers drive heterogeneity in embryonic stem cells
Hu S, Mahat DB, Chakraborty M, Hamilton M, Waterton S, Singh A, Lees J, Sharp P, Garg S. Enhancers drive heterogeneity in embryonic stem cells. Preprint. http://dx.doi.org/10.2139/ssrn.3836130.Peer-Reviewed Original Research
2020
MicroRNAs organize intrinsic variation into stem cell states
Chakraborty M, Hu S, Visness E, Del Giudice M, De Martino A, Bosia C, Sharp P, Garg S. MicroRNAs organize intrinsic variation into stem cell states. Proceedings Of The National Academy Of Sciences Of The United States Of America 2020, 117: 6942-6950. PMID: 32139605, PMCID: PMC7104302, DOI: 10.1073/pnas.1920695117.Peer-Reviewed Original Research
2016
Single-cell variability guided by microRNAs
Garg S, Sharp P. Single-cell variability guided by microRNAs. Science 2016, 352: 1390-1391. PMID: 27313022, DOI: 10.1126/science.aag1097.Peer-Reviewed Original Research
2015
MHC Class II Presentation Is Controlled by the Lysosomal Small GTPase, Arl8b
Michelet X, Garg S, Wolf B, Tuli A, Ricciardi-Castagnoli P, Brenner M. MHC Class II Presentation Is Controlled by the Lysosomal Small GTPase, Arl8b. The Journal Of Immunology 2015, 194: 2079-2088. PMID: 25637027, DOI: 10.4049/jimmunol.1401072.Peer-Reviewed Original ResearchADP-Ribosylation FactorsAnimalsAntigen PresentationAntigensBone Marrow CellsCD4-Positive T-LymphocytesCell LineChickensDendritic CellsEndosomesGene Expression RegulationHistocompatibility Antigens Class IILysosomesMiceMice, Inbred C57BLOvalbuminPrimary Cell CultureProtein TransportRNA, Small InterferingSignal TransductionSpleenChapter 7 RNAi screens of lysosomal trafficking
Garg S, Brenner M. Chapter 7 RNAi screens of lysosomal trafficking. Methods In Cell Biology 2015, 126: 119-138. PMID: 25665444, DOI: 10.1016/bs.mcb.2014.10.030.Chapters
News & Links
News
- October 10, 2024Source: Yale News
Salil Garg, MD, Receives NIH 'High-Risk, High-Reward' Award
- October 09, 2024Source: Yale News
Six Yale Researchers Receive NIH ‘High-Risk, High-Reward’ Awards
- February 28, 2024
Grants Awarded at YCC • 2024
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Oct 202619Monday
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Nov 20263Tuesday
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Dec 20267Monday
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