Gustavo A. Angarita, MD, MHS
Assistant Professor of PsychiatryCards
About
Research
Publications
2025
Quantitative sensory testing of pain in persons with opioid use disorder on opioid agonist treatment: a scoping review
Oliveira D, Costa G, Fontenele R, Córdoba-Delgado M, Funaro M, Campbell C, Fiellin D, Angarita G, De Aquino J. Quantitative sensory testing of pain in persons with opioid use disorder on opioid agonist treatment: a scoping review. Pain Medicine 2025, pnaf132. PMID: 40990827, DOI: 10.1093/pm/pnaf132.Peer-Reviewed Original ResearchQuantitative sensory testingOpioid use disorderOpioid agonist treatmentQST measuresAgonist treatmentQuantitative sensory testing methodologyQuantitative sensory testing outcomesUse disorderNon-OAT opioidsPain processing abnormalitiesPain sensitivity changesPain-related outcomesCold pain toleranceCentral sensitizationSystematic literature searchPain mechanismsPain modulationNeuroadaptive changesPain responseChronic painTreatment responseProlonged abstinencePainWeb of ScienceOpioidSafety of Stimulants Across Patient Populations
Oliva H, Prudente T, Mayerson T, Mignosa M, Oliva I, Potenza M, Jegede O, Angarita G. Safety of Stimulants Across Patient Populations. JAMA Network Open 2025, 8: e259492. PMID: 40343695, PMCID: PMC12065045, DOI: 10.1001/jamanetworkopen.2025.9492.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderRandomized clinical trialsAdverse eventsStimulant medicationData extractionSafety of stimulationRisk ratioIncreased riskMethodological quality assessmentPreferred Reporting ItemsPatient populationClinical conditionsDiverse patient populationsRisk of biasSafety of stimulant medicationsUnclear risk of biasTreatment of attention-deficit/hyperactivity disorderOverall AEsRandom-effects modelWeb of ScienceBinge Eating DisorderStimulant use disorderComprehensive literature searchMain OutcomesReporting Items
2016
Domain adaptation methods for improving lab-to-field generalization of cocaine detection using wearable ECG
Natarajan A, Angarita G, Gaiser E, Malison R, Ganesan D, Marlin BM. Domain adaptation methods for improving lab-to-field generalization of cocaine detection using wearable ECG. 2016, 2016: 875-885. PMID: 28090605, PMCID: PMC5235327, DOI: 10.1145/2971648.2971666.Peer-Reviewed Original Research
2014
Conditional random fields for morphological analysis of wireless ECG signals
Natarajan A, Gaiser E, Angarita G, Malison R, Ganesan D, Marlin B. Conditional random fields for morphological analysis of wireless ECG signals. 2014, 2014: 370-379. PMID: 26726321, PMCID: PMC4697765, DOI: 10.1145/2649387.2649414.Peer-Reviewed Original ResearchECG signalsConditional random field modelOpen-source toolkitConditional Random FieldsMobile sensing technologiesIndependent prediction modelsRandom field modelSensor dataNew computational toolsSensing technologyRandom fieldsComputational toolsNovel approachField modelPrediction modelDiverse applicationsSame featuresNon-stationary signalsLab-based studiesUsersToolkitProblemTechnologyFrameworkCapability
2013
Abstinence-related changes in sleep during treatment for cocaine dependence
Angarita GA, Canavan SV, Forselius E, Bessette A, Pittman B, Morgan PT. Abstinence-related changes in sleep during treatment for cocaine dependence. Drug And Alcohol Dependence 2013, 134: 343-347. PMID: 24315572, PMCID: PMC4396819, DOI: 10.1016/j.drugalcdep.2013.11.007.Peer-Reviewed Original ResearchConceptsTotal sleep timeExtended abstinenceOutpatient cognitive behavioral therapyAbstinence-related changesDecreased slow wave sleepInpatient substance abuse treatmentCognitive behavioral therapySleep timeCocaine usersPolysomnographic sleepChronic cocaine usersCocaine-dependent participantsSubstance abuse treatmentThrice weekly urine toxicologyBehavioral therapyWeeks of abstinenceOverall sleep qualityAbuse treatmentDays abstinentDependent participantsREM sleep latencySleep qualityCocaine dependenceSlow-wave sleepAbstinence
2009
Regulation of cocaine self-administration in humans: Lack of evidence for loading and maintenance phases
Angarita GA, Pittman B, Gueorguieva R, Kalayasiri R, Lynch WJ, Sughondhabirom A, Morgan PT, Malison RT. Regulation of cocaine self-administration in humans: Lack of evidence for loading and maintenance phases. Pharmacology Biochemistry And Behavior 2009, 95: 51-55. PMID: 20005893, PMCID: PMC2824073, DOI: 10.1016/j.pbb.2009.12.005.Peer-Reviewed Original Research
2008
A randomized, double-blind, placebo-controlled trial of long-acting risperidone in cocaine-dependent men.
Loebl T, Angarita GA, Pachas GN, Huang KL, Lee SH, Nino J, Logvinenko T, Culhane MA, Evins AE. A randomized, double-blind, placebo-controlled trial of long-acting risperidone in cocaine-dependent men. The Journal Of Clinical Psychiatry 2008, 69: 480-6. PMID: 18294021, DOI: 10.4088/jcp.v69n0321.Peer-Reviewed Original Research
2007
No-Show for Treatment in Substance Abuse Patients with Comorbid Symptomatology: Validity Results from a Controlled Trial of the ASAM Patient Placement Criteria.
Angarita GA, Reif S, Pirard S, Lee S, Sharon E, Gastfriend DR. No-Show for Treatment in Substance Abuse Patients with Comorbid Symptomatology: Validity Results from a Controlled Trial of the ASAM Patient Placement Criteria. Journal Of Addiction Medicine 2007, 1: 79-87. PMID: 21768939, DOI: 10.1097/ADM.0b013e3180634c1d.Peer-Reviewed Original Research
2005
Prevalence of physical and sexual abuse among substance abuse patients and impact on treatment outcomes.
Pirard S, Sharon E, Kang SK, Angarita GA, Gastfriend DR. Prevalence of physical and sexual abuse among substance abuse patients and impact on treatment outcomes. Drug And Alcohol Dependence 2005, 78: 57-64. PMID: 15769558, DOI: 10.1016/j.drugalcdep.2004.09.005.Peer-Reviewed Original Research
Clinical Trials
Current Trials
Brain Imaging and Synaptic Plasticity
HIC ID2000029552RolePrincipal InvestigatorPrimary Completion Date06/30/2026Recruiting ParticipantsGenderBothAge21 years - 60 yearsEligibility for Participation in Neuroimaging Studies
HIC ID2000027842RoleSub InvestigatorPrimary Completion Date12/31/2023Recruiting ParticipantsHPA axis function in the brains of PTSD, Trauma Exposed, or Otherwise Healthy research participants utilizing PET and MRI imaging
HIC ID2000028748RoleSub InvestigatorPrimary Completion Date08/31/2025Recruiting ParticipantsGenderBothAge18 years - 55 yearsStudying the Adult Brain
HIC ID2000025671RoleSub InvestigatorPrimary Completion Date07/31/2025Recruiting ParticipantsImaging the Dopamine Transporter in Parkinson's Disease
HIC ID2000023896RoleSub InvestigatorPrimary Completion Date12/31/2020Recruiting ParticipantsGenderBothAge40+ years
Clinical Care
Overview
Gustavo A. Angarita, MD, specializes in psychiatry with a focus on addiction psychiatry, particularly related to cocaine addiction. He is the director of the Yale Cocaine Research Clinic, inpatient chief of the Clinical Neuroscience Research Unit, and the medical director of the Forensic Drug Diversion Clinic.
Dr. Angarita is dedicated to understanding and treating substance use disorders, aiming to develop effective treatments for cocaine dependence. As an assistant professor of psychiatry at Yale School of Medicine, his research interests include the regulation of cocaine self-administration, validation of remote wireless sensor network technology for detecting cocaine use, and investigating cocaine-induced sleep deficits and their therapeutic effects.
Dr. Angarita received his medical degree from Universidad Militar Nueva Granada. He completed a research fellowship in addictions at Harvard Medical School, followed by a residency in adult psychiatry at Yale School of Medicine. He continued his specialization with a clinical and research fellowship in addictions psychiatry at Harvard Medical School.
Clinical Specialties
Board Certifications
Addiction Psychiatry
- Certification Organization
- AB of Psychiatry & Neurology
- Original Certification Date
- 2012
Psychiatry
- Certification Organization
- AB of Psychiatry & Neurology
- Original Certification Date
- 2011
News
News
- September 25, 2025Source: Pain Medicine
Quantitative Sensory Testing of Pain in Persons with Opioid Use Disorder on Opioid Agonist Treatment: A Scoping Review
- August 11, 2025
Angarita, De Aquino Named Mentors for ACNP Near-Peer Mentorship Program
- May 09, 2025Source: JAMA Network Open
Safety of Stimulants Across Patient Populations
- February 28, 2025
Pulido Saavedra Selected to Receive ISAM Travel Award