Fields of Study
- Cancer Biology: leukemogenesis, metastasis, growth control, genome integrity, immune checkpoint therapy
- Cell Biology: cytoskeleton, nuclear structure and dynamics
- Cell Signaling: kinases, phosphatases, growth signaling
- Epithelial cell biology: epithelial patterning, skin development and disease
- Immunology: autoimmune disease, immunotherapy, systems biology
- Genetics: disease etiology, birth defects
- Lung function: cystic fibrosis, lung disease, idiopathic lung fibrosis
- Maternal-Fetal Medicine
- Metabolism: signaling and systems biology, diabetes
- Neuroscience: pathogenesis of brain disease, neurogenomics
- Organ homeostasis and injury: pancreatitis, kidney injury, macular degeneration, scleroderma
PHAR 504a / PTB 504a, Molecular Mechanisms of Drug Actions
PHAR 550a / C&MP 550a / ENAS 550a / MCDB 550a / PTB 550a, Physiological Systems
CBIO 604b / PTB 604b, Physiologic Function and Cellular Structure of Organ Systems
PATH 690a / PTB690a, Molecular Mechanisms of Disease
Joining a Lab for the Dissertation Research
Qualifying exam committee
Preparation for the qualifying exam
Preparation and submission of the written research proposal
Prospectus & Thesis Committee
Format and Prospectus Approval
Individual Professional Development Plan (IDP)
External examiner visit
Responsible Conduct of Research
All PTB students are required to teach the equivalent of two courses at the TF-10 level (10 hours per week) or one course at the TF-20 level (20 hours per week). These can be chosen from numerous lecture, laboratory and seminar courses offered at the undergraduate, graduate or medical school levels. Students generally teach in the 3rd year but may also begin teaching during the spring of their 2nd year with permission of the thesis advisor and PTB DGS. MD/PhD students are only required to TA one course at the TF-10 level.
Prior to the first semester of teaching, each PTB student must attend the Teaching @ Yale Day Orientation. Students are also encouraged to take one or more of the short teaching courses and workshops offered by the Poorvu Center for Teaching and Learning.
Leave of Absence
Students who wish or need to interrupt their study temporarily may request a leave of absence. There are three types of leave—personal, medical, and parental.
General policies, as well as specific requirements for any type of leave may be found on the GSAS website.
Required Coursework Timeline
Term 1 – Year 1, Fall Semester
At least one but typically two of the following:
- Physiological Systems
- Molecular Mechanisms of Disease
- Principles of Pharmacology
Seminar: Topics in Translational Molecular Medicine, Pharmacology and Physiology – fall
Laboratory Rotations, Responsible Conduct in Research (“Ethics in Science”)
Term 2 – Year 1, Spring Semester
Physiologic function and cellular structure of organ systems (new PTB course, will replace the former Systems Cell Biology)
Seminar: Topics in Translational Molecular Medicine, Pharmacology and Physiology – spring
Introduction to Biostatistics in Clinical Investigation (or other statistics-based course such as ENAS549).
Term 3 – Year 2, Fall Semester
Mentored Clinical Experience
Grant Writing CourseAdditional electives (if needed or desired)
Term 4 – Year 2, Spring Semester
Mentored Clinical Experience
Additional electives (if needed or desired)
Note: Students who participate in the Medical Research Scholars Program, which currently serves students in all tracks and PhD programs of the BBS, would participate in an additional year of the Mentored Clinical Experience in Year 3.
ApplyStudents seeking admission into the Program in Translational BioMedicine must apply through the Biological and Biomedical Sciences (BBS) program.
HandbookThis handbook is intended to be a source of information for graduate students containing information on the structure of the program, course descriptions and requirements, faculty information, contact information, university services, and more.Read More