Differential Cognitive Performance in Females and Males with Regular Cannabis Use
Martin A, D’Souza D, Newman SD, Hetrick WP, O’Donnell B. Differential Cognitive Performance in Females and Males with Regular Cannabis Use. Journal Of The International Neuropsychological Society 2021, 27: 570-580. PMID: 34261548, PMCID: PMC8830784, DOI: 10.1017/s1355617721000606.Peer-Reviewed Original ResearchConceptsRegular cannabis useCannabis useCognitive measuresPsychomotor speedBiological sexHopkins Verbal Learning TestDifferential cognitive performanceNon-using peersVerbal Learning TestMeasures of intelligenceWechsler Abbreviated ScaleDigit symbol testGreatest group differencesVerbal learningDigit spanLearning TestCognitive performanceAbbreviated ScaleNeurocognitive deficitsCognitive deficitsSymbol testCannabis exposurePsychomotor performanceGroup differencesCognitionAnalysis of circulating exosomes reveals a peripheral signature of astrocytic pathology in schizophrenia
Ranganathan M, Rahman M, Ganesh S, D’Souza D, Skosnik PD, Radhakrishnan R, Pathania S, Mohanakumar T. Analysis of circulating exosomes reveals a peripheral signature of astrocytic pathology in schizophrenia. The World Journal Of Biological Psychiatry 2021, 23: 33-45. PMID: 33821753, DOI: 10.1080/15622975.2021.1907720.Peer-Reviewed Original ResearchConceptsHealthy controlsSex-matched healthy controlsBlood-brain barrierNovel peripheral biomarkersPlasma-derived exosomesAstroglial pathologyWestern blot analysisPeripheral biomarkersSynaptophysin levelsBrain barrierPeripheral signatureAstrocytic pathologyGFAP concentrationsSchizophrenia patientsExosomal protein expressionNeuropsychiatric disordersNeurodegenerative disordersProtein immunopositivitySchizophreniaProtein expressionGroup differencesDisordersPatientsScarce dataConcentration of exosomes