Primary Faculty Publications

Matos-Cruz V, Schneider ER, Mastrotto M, Merriman DK, Bagriantsev SN, Gracheva EO: Molecular Prerequisites for Diminished Cold Sensitivity in Ground Squirrels and Hamsters. Cell Rep. 2017 Dec 19. PMID: 29262313

Schneider ER, Anderson EO, Mastrotto M, Matson JD, Schulz VP, Gallagher PG, LaMotte RH, Gracheva EO, Bagriantsev SN: Molecular basis of tactile specialization in the duck bill. Proc Natl Acad Sci U S A. 2017 Dec 5; 2017 Nov 6. PMID: 29109250

Sepehri Rad M, Choi Y, Cohen LB, Baker BJ, Zhong S, Storace DA, Braubach OR: Voltage and Calcium Imaging of Brain Activity. Biophys J. 2017 Nov 21; 2017 Nov 1. PMID: 29102396

Mohler K, Aerni HR, Gassaway B, Ling J, Ibba M, Rinehart J: MS-READ: Quantitative measurement of amino acid incorporation. Biochim Biophys Acta. 2017 Nov; 2017 Jan 24. PMID: 28130155

Ma L, Cai Y, Li Y, Jiao J, Wu Z, O'Shaughnessy B, De Camilli P, Karatekin E, Zhang Y: Single-molecule force spectroscopy of protein-membrane interactions. Elife. 2017 Oct 30; 2017 Oct 30. PMID: 29083305

Ferrandino G, Kaspari RR, Spadaro O, Reyna-Neyra A, Perry RJ, Cardone R, Kibbey RG, Shulman GI, Dixit VD, Carrasco N: Pathogenesis of hypothyroidism-induced NAFLD is driven by intra- and extrahepatic mechanisms. Proc Natl Acad Sci U S A. 2017 Oct 24; 2017 Oct 10. PMID: 29073114

Glogowska E, Schneider ER, Maksimova Y, Schulz VP, Lezon-Geyda K, Wu J, Radhakrishnan K, Keel SB, Mahoney D, Freidmann AM, Altura RA, Gracheva EO, Bagriantsev SN, Kalfa TA, Gallagher PG: Novel mechanisms of PIEZO1 dysfunction in hereditary xerocytosis. Blood. 2017 Oct 19; 2017 Jul 17. PMID: 28716860

Wu Z, Thiyagarajan S, O'Shaughnessy B, Karatekin E: Regulation of Exocytotic Fusion Pores by SNARE Protein Transmembrane Domains. Front Mol Neurosci. 2017; 2017 Oct 10. PMID: 29066949

D'Lima NG, Khitun A, Rosenbloom AD, Yuan P, Gassaway BM, Barber KW, Rinehart J, Slavoff SA: Comparative Proteomics Enables Identification of Nonannotated Cold Shock Proteins in E. coli. J Proteome Res. 2017 Oct 6; 2017 Sep 19. PMID: 28861998

Hughes ME, Abruzzi KC, Allada R, Anafi R, Arpat AB, Asher G, Baldi P, de Bekker C, Bell-Pedersen D, Blau J, Brown S, Ceriani MF, Chen Z, Chiu JC, Cox J, Crowell AM, DeBruyne JP, Dijk DJ, DiTacchio L, Doyle FJ, Duffield GE, Dunlap JC, Eckel-Mahan K, Esser KA, FitzGerald GA, Forger DB, Francey LJ, Fu YH, Gachon F, Gatfield D, de Goede P, Golden SS, Green C, Harer J, Harmer S, Haspel J, Hastings MH, Herzel H, Herzog ED, Hoffmann C, Hong C, Hughey JJ, Hurley JM, de la Iglesia HO, Johnson C, Kay SA, Koike N, Kornacker K, Kramer A, Lamia K, Leise T, Lewis SA, Li J, Li X, Liu AC, Loros JJ, Martino TA, Menet JS, Merrow M, Millar AJ, Mockler T, Naef F, Nagoshi E, Nitabach MN, Olmedo M, Nusinow DA, Ptáček LJ, Rand D, Reddy AB, Robles MS, Roenneberg T, Rosbash M, Ruben MD, Rund SSC, Sancar A, Sassone-Corsi P, Sehgal A, Sherrill-Mix S, Skene DJ, Storch KF, Takahashi JS, Ueda HR, Wang H, Weitz C, Westermark PO, Wijnen H, Xu Y, Wu G, Yoo SH, Young M, Zhang EE, Zielinski T, Hogenesch JB: Guidelines for Genome-Scale Analysis of Biological Rhythms. J Biol Rhythms. 2017 Oct; 2017 Nov 3. PMID: 29098954

Fan Y, Evans CR, Barber KW, Banerjee K, Weiss KJ, Margolin W, Igoshin OA, Rinehart J, Ling J: Heterogeneity of Stop Codon Readthrough in Single Bacterial Cells and Implications for Population Fitness. Mol Cell. 2017 Sep 7; 2017 Aug 3. PMID: 28781237

Martenson JS, Yamasaki T, Chaudhury NH, Albrecht D, Tomita S: Assembly rules for GABA_A receptor complexes in the brain. Elife. 2017 Aug 17; 2017 Aug 17. PMID: 28816653

Li J, Hatano R, Xu S, Wan L, Yang L, Weinstein AM, Palmer L, Wang T: Gender difference in kidney electrolyte transport. I. Role of AT_1a receptor in thiazide-sensitive Na⁺-Cl^- cotransporter activity and expression in male and female mice. Am J Physiol Renal Physiol. 2017 Aug 1; 2017 May 31. PMID: 28566500

Tomita S, Bloodgood BL: Editorial overview: Molecular neuroscience 2017. Curr Opin Neurobiol. 2017 Aug; 2017 Jul 20. PMID: 28736237

Chen D, Sitaraman D, Chen N, Jin X, Han C, Chen J, Sun M, Baker BS, Nitabach MN, Pan Y: Genetic and neuronal mechanisms governing the sex-specific interaction between sleep and sexual behaviors in Drosophila. Nat Commun. 2017 Jul 28; 2017 Jul 28. PMID: 28754889

Storace DA, Cohen LB: Measuring the olfactory bulb input-output transformation reveals a contribution to the perception of odorant concentration invariance. Nat Commun. 2017 Jul 19; 2017 Jul 19. PMID: 28724907

Ferrandino G, Kaspari RR, Reyna-Neyra A, Boutagy NE, Sinusas AJ, Carrasco N: An extremely high dietary iodide supply forestalls severe hypothyroidism in Na⁺/I^- symporter (NIS) knockout mice. Sci Rep. 2017 Jul 13; 2017 Jul 13. PMID: 28706256

King AN, Barber AF, Smith AE, Dreyer AP, Sitaraman D, Nitabach MN, Cavanaugh DJ, Sehgal A: A Peptidergic Circuit Links the Circadian Clock to Locomotor Activity. Curr Biol. 2017 Jul 10; 2017 Jun 29. PMID: 28669757

Hwang JY, Chung JJ: Sex at Atomic Resolution. Cell. 2017 Jun 15. PMID: 28622504

Wang T, Weinbaum S, Weinstein AM: Regulation of glomerulotubular balance: flow-activated proximal tubule function. Pflugers Arch. 2017 Jun; 2017 Mar 7. PMID: 28271233

Mostafavi H, Thiyagarajan S, Stratton BS, Karatekin E, Warner JM, Rothman JE, O'Shaughnessy B: Entropic forces drive self-organization and membrane fusion by SNARE proteins. Proc Natl Acad Sci U S A. 2017 May 23; 2017 May 10. PMID: 28490503

Park Y, Reyna-Neyra A, Philippe L, Thoreen CC: mTORC1 Balances Cellular Amino Acid Supply with Demand for Protein Synthesis through Post-transcriptional Control of ATF4. Cell Rep. 2017 May 9. PMID: 28494858

Allen CN, Nitabach MN, Colwell CS: Membrane Currents, Gene Expression, and Circadian Clocks. Cold Spring Harb Perspect Biol. 2017 May 1; 2017 May 1. PMID: 28246182

Inoue K, Balkin DM, Liu L, Nandez R, Wu Y, Tian X, Wang T, Nussbaum R, De Camilli P, Ishibe S: Kidney Tubular Ablation of Ocrl/Inpp5b Phenocopies Lowe Syndrome Tubulopathy. J Am Soc Nephrol. 2017 May; 2016 Nov 28. PMID: 27895154

Mohler K, Mann R, Bullwinkle TJ, Hopkins K, Hwang L, Reynolds NM, Gassaway B, Aerni HR, Rinehart J, Polymenis M, Faull K, Ibba M: Editing of misaminoacylated tRNA controls the sensitivity of amino acid stress responses in Saccharomyces cerevisiae. Nucleic Acids Res. 2017 Apr 20. PMID: 28168297

Bai JP, Moeini-Naghani I, Zhong S, Li FY, Bian S, Sigworth FJ, Santos-Sacchi J, Navaratnam D: Current carried by the Slc26 family member prestin does not flow through the transporter pathway. Sci Rep. 2017 Apr 19; 2017 Apr 19. PMID: 28422190

Ghosh DD, Nitabach MN, Zhang Y, Harris G: Multisensory integration in C. elegans. Curr Opin Neurobiol. 2017 Apr; 2017 Mar 6. PMID: 28273525

Wu Z, Bello OD, Thiyagarajan S, Auclair SM, Vennekate W, Krishnakumar SS, O'Shaughnessy B, Karatekin E: Dilation of fusion pores by crowding of SNARE proteins. Elife. 2017 Mar 27; 2017 Mar 27. PMID: 28346138

Park HB, Perez CE, Barber KW, Rinehart J, Crawford JM: Genome mining unearths a hybrid nonribosomal peptide synthetase-like-pteridine synthase biosynthetic gene cluster. Elife. 2017 Mar 15; 2017 Mar 15. PMID: 28431213

Yamasaki T, Hoyos-Ramirez E, Martenson JS, Morimoto-Tomita M, Tomita S: GARLH Family Proteins Stabilize GABA_A Receptors at Synapses. Neuron. 2017 Mar 8. PMID: 28279354

Adhikary S, Deredge DJ, Nagarajan A, Forrest LR, Wintrode PL, Singh SK: Conformational dynamics of a neurotransmitter:sodium symporter in a lipid bilayer. Proc Natl Acad Sci U S A. 2017 Mar 7; 2017 Feb 21. PMID: 28223522

Chung JJ, Miki K, Kim D, Shim SH, Shi HF, Hwang JY, Cai X, Iseri Y, Zhuang X, Clapham DE: CatSperζ regulates the structural continuity of sperm Ca²⁺ signaling domains and is required for normal fertility. Elife. 2017 Feb 23; 2017 Feb 23. PMID: 28226241

Ravera S, Reyna-Neyra A, Ferrandino G, Amzel LM, Carrasco N: The Sodium/Iodide Symporter (NIS): Molecular Physiology and Preclinical and Clinical Applications. Annu Rev Physiol. 2017 Feb 10. PMID: 28192058

Thoreen CC: The molecular basis of mTORC1-regulated translation. Biochem Soc Trans. 2017 Feb 8. PMID: 28202675

Castañeda-Bueno M, Arroyo JP, Zhang J, Puthumana J, Yarborough O 3rd, Shibata S, Rojas-Vega L, Gamba G, Rinehart J, Lifton RP: Phosphorylation by PKC and PKA regulate the kinase activity and downstream signaling of WNK4. Proc Natl Acad Sci U S A. 2017 Jan 31; 2017 Jan 17. PMID: 28096417

Matlin KS, Caplan MJ: The secretory pathway at 50: a golden anniversary for some momentous grains of silver. Mol Biol Cell. 2017 Jan 15. PMID: 28082520

Padovano V, Kuo IY, Stavola LK, Aerni HR, Flaherty BJ, Chapin HC, Ma M, Somlo S, Boletta A, Ehrlich BE, Rinehart J, Caplan MJ: The polycystins are modulated by cellular oxygen-sensing pathways and regulate mitochondrial function. Mol Biol Cell. 2017 Jan 15; 2016 Nov 23. PMID: 27881662

Anderson EO, Schneider ER, Bagriantsev SN: Piezo2 in Cutaneous and Proprioceptive Mechanotransduction in Vertebrates. Curr Top Membr. 2017; 2017 Jan 16. PMID: 28728817

Barber KW, Rinehart J: Expression of Recombinant Phosphoproteins for Signal Transduction Studies. Methods Mol Biol. 2017. PMID: 28730473

Hoffman JF: Biconcave shape of human red-blood-cell ghosts relies on density differences between the rim and dimple of the ghost's plasma membrane. Proc Natl Acad Sci U S A. 2016 Dec 20; 2016 Dec 5. PMID: 27930321

Ghosh DD, Sanders T, Hong S, McCurdy LY, Chase DL, Cohen N, Koelle MR, Nitabach MN: Neural Architecture of Hunger-Dependent Multisensory Decision Making in C. elegans. Neuron. 2016 Dec 7; 2016 Nov 17. PMID: 27866800

Stoops EH, Hull M, Caplan MJ: Newly synthesized and recycling pools of the apical protein gp135 do not occupy the same compartments. Traffic. 2016 Dec; 2016 Nov 1. PMID: 27649479

Han J, Lee SH, Giebisch G, Wang T: Potassium Channelopathies and Gastrointestinal Ulceration. Gut Liver. 2016 Nov 15. PMID: 27784845

Park J, Chávez AE, Mineur YS, Morimoto-Tomita M, Lutzu S, Kim KS, Picciotto MR, Castillo PE, Tomita S: CaMKII Phosphorylation of TARPγ-8 Is a Mediator of LTP and Learning and Memory. Neuron. 2016 Oct 5; 2016 Sep 22. PMID: 27667007

Laursen WJ, Schneider ER, Merriman DK, Bagriantsev SN, Gracheva EO: Low-cost functional plasticity of TRPV1 supports heat tolerance in squirrels and camels. Proc Natl Acad Sci U S A. 2016 Oct 4; 2016 Sep 16. PMID: 27638213

Chung JJ: Sugar-coated sperm. Mol Reprod Dev. 2016 Oct. PMID: 27591546

Ferrandino G, Nicola JP, Sánchez YE, Echeverria I, Liu Y, Amzel LM, Carrasco N: Na+ coordination at the Na2 site of the Na+/I- symporter. Proc Natl Acad Sci U S A. 2016 Sep 13; 2016 Aug 25. PMID: 27562170

Kay AR, Raccuglia D, Scholte J, Sivan-Loukianova E, Barwacz CA, Armstrong SR, Guymon CA, Nitabach MN, Eberl DF: Goggatomy: A Method for Opening Small Cuticular Compartments in Arthropods for Physiological Experiments. Front Physiol. 2016; 2016 Sep 12. PMID: 27695420

Ferdaus MZ, Barber KW, López-Cayuqueo KI, Terker AS, Argaiz ER, Gassaway BM, Chambrey R, Gamba G, Rinehart J, McCormick JA: SPAK and OSR1 play essential roles in potassium homeostasis through actions on the distal convoluted tubule. J Physiol. 2016 Sep 1; 2016 May 29. PMID: 27068441

Nikolaus J, Karatekin E: SNARE-mediated Fusion of Single Proteoliposomes with Tethered Supported Bilayers in a Microfluidic Flow Cell Monitored by Polarized TIRF Microscopy. J Vis Exp. 2016 Aug 24; 2016 Aug 24. PMID: 27585113

Raccuglia D, McCurdy LY, Demir M, Gorur-Shandilya S, Kunst M, Emonet T, Nitabach MN: Presynaptic GABA Receptors Mediate Temporal Contrast Enhancement in Drosophila Olfactory Sensory Neurons and Modulate Odor-Driven Behavioral Kinetics. eNeuro. 2016 Jul-Aug; 2016 Aug 23. PMID: 27588305

Renier C, Do J, Reyna-Neyra A, Foster D, De A, Vogel H, Jeffrey SS, Tse V, Carrasco N, Wapnir I: Regression of experimental NIS-expressing breast cancer brain metastases in response to radioiodide/gemcitabine dual therapy. Oncotarget. 2016 Aug 23. PMID: 27363025

Siefert AL, Caplan MJ, Fahmy TM: Artificial bacterial biomimetic nanoparticles synergize pathogen-associated molecular patterns for vaccine efficacy. Biomaterials. 2016 Aug; 2016 Apr 1. PMID: 27162077

Srivastava KD, Siefert A, Fahmy TM, Caplan MJ, Li XM, Sampson HA: Investigation of peanut oral immunotherapy with CpG/peanut nanoparticles in a murine model of peanut allergy. J Allergy Clin Immunol. 2016 Aug; 2016 Apr 26. PMID: 27130858

Straub C, Noam Y, Nomura T, Yamasaki M, Yan D, Fernandes HB, Zhang P, Howe JR, Watanabe M, Contractor A, Tomita S: Distinct Subunit Domains Govern Synaptic Stability and Specificity of the Kainate Receptor. Cell Rep. 2016 Jul 12; 2016 Jun 23. PMID: 27346345

Lv C, Stewart WJ, Akanyeti O, Frederick C, Zhu J, Santos-Sacchi J, Sheets L, Liao JC, Zenisek D: Synaptic Ribbons Require Ribeye for Electron Density, Proper Synaptic Localization, and Recruitment of Calcium Channels. Cell Rep. 2016 Jun 21; 2016 Jun 9. PMID: 27292637

Wu Z, Auclair SM, Bello O, Vennekate W, Dudzinski NR, Krishnakumar SS, Karatekin E: Nanodisc-cell fusion: control of fusion pore nucleation and lifetimes by SNARE protein transmembrane domains. Sci Rep. 2016 Jun 6; 2016 Jun 6. PMID: 27264104

Caplan MJ: The tail of polycystin-1 pays the kidney a complement. Am J Physiol Renal Physiol. 2016 Jun 1; 2016 Mar 23. PMID: 27009337

Zuo L, Tan Y, Wang Z, Wang KS, Zhang X, Chen X, Li CS, Wang T, Luo X: Long noncoding RNAs in psychiatric disorders. Psychiatr Genet. 2016 Jun. PMID: 26974119

Schneider ER, Gracheva EO, Bagriantsev SN: Evolutionary Specialization of Tactile Perception in Vertebrates. Physiology (Bethesda). 2016 May. PMID: 27053733

Storace D, Sepehri Rad M, Kang B, Cohen LB, Hughes T, Baker BJ: Toward Better Genetically Encoded Sensors of Membrane Potential. Trends Neurosci. 2016 May. PMID: 27130905

Miller MR, Mannowetz N, Iavarone AT, Safavi R, Gracheva EO, Smith JF, Hill RZ, Bautista DM, Kirichok Y, Lishko PV: Unconventional endocannabinoid signaling governs sperm activation via the sex hormone progesterone. Science. 2016 Apr 29; 2016 Mar 17. PMID: 26989199

Arif Pavel M, Lv C, Ng C, Yang L, Kashyap P, Lam C, Valentino V, Fung HY, Campbell T, Møller SG, Zenisek D, Holtzman NG, Yu Y: Function and regulation of TRPP2 ion channel revealed by a gain-of-function mutant. Proc Natl Acad Sci U S A. 2016 Apr 26; 2016 Apr 11. PMID: 27071085

Gruber DF, Loew ER, Deheyn DD, Akkaynak D, Gaffney JP, Smith WL, Davis MP, Stern JH, Pieribone VA, Sparks JS: Biofluorescence in Catsharks (Scyliorhinidae): Fundamental Description and Relevance for Elasmobranch Visual Ecology. Sci Rep. 2016 Apr 25; 2016 Apr 25. PMID: 27109385

Caplan MJ: 2016 Robert W. Berliner Award for Excellence in Renal Physiology. Am J Physiol Renal Physiol. 2016 Apr 15; 2016 Mar 9. PMID: 26962101

Stratton BS, Warner JM, Wu Z, Nikolaus J, Wei G, Wagnon E, Baddeley D, Karatekin E, O'Shaughnessy B: Cholesterol Increases the Openness of SNARE-Mediated Flickering Fusion Pores. Biophys J. 2016 Apr 12. PMID: 27074679

Jensen KH, Brandt SS, Shigematsu H, Sigworth FJ: Statistical modeling and removal of lipid membrane projections for cryo-EM structure determination of reconstituted membrane proteins. J Struct Biol. 2016 Apr; 2016 Feb 1. PMID: 26835990

Davis BA, Nagarajan A, Forrest LR, Singh SK: Mechanism of Paroxetine (Paxil) Inhibition of the Serotonin Transporter. Sci Rep. 2016 Apr 1; 2016 Apr 1. PMID: 27032980

Dong K, Yan Q, Lu M, Wan L, Hu H, Guo J, Boulpaep E, Wang W, Giebisch G, Hebert SC, Wang T: Romk1 Knockout Mice Do Not Produce Bartter Phenotype but Exhibit Impaired K Excretion. J Biol Chem. 2016 Mar 4; 2016 Jan 4. PMID: 26728465

Michaelides EM, Kuang H, Pieribone VA: Dickkopf-related Protein 3 as a Sensitive and Specific Marker for Cerebrospinal Fluid Leaks. Otol Neurotol. 2016 Mar. PMID: 26837002

Abdelfattah AS, Farhi SL, Zhao Y, Brinks D, Zou P, Ruangkittisakul A, Platisa J, Pieribone VA, Ballanyi K, Cohen AE, Campbell RE: A Bright and Fast Red Fluorescent Protein Voltage Indicator That Reports Neuronal Activity in Organotypic Brain Slices. J Neurosci. 2016 Feb 24. PMID: 26911693

Erlenhardt N, Yu H, Abiraman K, Yamasaki T, Wadiche JI, Tomita S, Bredt DS: Porcupine Controls Hippocampal AMPAR Levels, Composition, and Synaptic Transmission. Cell Rep. 2016 Feb 2; 2016 Jan 14. PMID: 26776514

Sigworth FJ: Principles of cryo-EM single-particle image processing. Microscopy (Oxf). 2016 Feb; 2015 Dec 24. PMID: 26705325

Sitaraman D, Aso Y, Rubin GM, Nitabach MN: Corrigendum: Control of Sleep by Dopaminergic Inputs to the Drosophila Mushroom Body. Front Neural Circuits. 2015; 2015 Dec 22. PMID: 26733821

Zuo L, Wang T, Lin X, Wang J, Tan Y, Wang X, Yu X, Luo X: Sex difference of autosomal alleles in populations of European and African descent. Genes Genomics. 2015 Dec 1; 2015 Sep 3. PMID: 26702338

Farr GA, Hull M, Stoops EH, Bateson R, Caplan MJ: Dual pulse-chase microscopy reveals early divergence in the biosynthetic trafficking of the Na,K-ATPase and E-cadherin. Mol Biol Cell. 2015 Dec 1; 2015 Sep 30. PMID: 26424804

Amiram M, Haimovich AD, Fan C, Wang YS, Aerni HR, Ntai I, Moonan DW, Ma NJ, Rovner AJ, Hong SH, Kelleher NL, Goodman AL, Jewett MC, Söll D, Rinehart J, Isaacs FJ: Evolution of translation machinery in recoded bacteria enables multi-site incorporation of nonstandard amino acids. Nat Biotechnol. 2015 Dec; 2015 Nov 16. PMID: 26571098

Pardo JP, González-Andrade M, Allen K, Kuroda T, Slayman CL, Rivetta A: A structural model for facultative anion channels in an oligomeric membrane protein: the yeast TRK (K(+)) system. Pflugers Arch. 2015 Dec; 2015 Jun 24. PMID: 26100673

Sung U, Sepehri-Rad M, Piao HH, Jin L, Hughes T, Cohen LB, Baker BJ: Developing Fast Fluorescent Protein Voltage Sensors by Optimizing FRET Interactions. PLoS One. 2015; 2015 Nov 20. PMID: 26587834

Sitaraman D, Aso Y, Jin X, Chen N, Felix M, Rubin GM, Nitabach MN: Propagation of Homeostatic Sleep Signals by Segregated Synaptic Microcircuits of the Drosophila Mushroom Body. Curr Biol. 2015 Nov 16; 2015 Oct 8. PMID: 26455303

Gruber DF, Gaffney JP, Mehr S, DeSalle R, Sparks JS, Platisa J, Pieribone VA: Adaptive Evolution of Eel Fluorescent Proteins from Fatty Acid Binding Proteins Produces Bright Fluorescence in the Marine Environment. PLoS One. 2015; 2015 Nov 11. PMID: 26561348

Sitaraman D, Aso Y, Rubin GM, Nitabach MN: Control of Sleep by Dopaminergic Inputs to the Drosophila Mushroom Body. Front Neural Circuits. 2015; 2015 Nov 9. PMID: 26617493

Alves DS, Thulin G, Loffing J, Kashgarian M, Caplan MJ: Akt Substrate of 160 kD Regulates Na+,K+-ATPase Trafficking in Response to Energy Depletion and Renal Ischemia. J Am Soc Nephrol. 2015 Nov; 2015 Mar 18. PMID: 25788531

Stoops EH, Hull M, Olesen C, Mistry K, Harder JL, Rivera-Molina F, Toomre D, Caplan MJ: The periciliary ring in polarized epithelial cells is a hot spot for delivery of the apical protein gp135. J Cell Biol. 2015 Oct 26. PMID: 26504168

Oikawa T, Wauthier E, Dinh TA, Selitsky SR, Reyna-Neyra A, Carpino G, Levine R, Cardinale V, Klimstra D, Gaudio E, Alvaro D, Carrasco N, Sethupathy P, Reid LM: Model of fibrolamellar hepatocellular carcinomas reveals striking enrichment in cancer stem cells. Nat Commun. 2015 Oct 6; 2015 Oct 6. PMID: 26437858

Gracheva EO, Bagriantsev SN: Evolutionary adaptation to thermosensation. Curr Opin Neurobiol. 2015 Oct; 2015 Feb 17. PMID: 25698346

Nicola JP, Reyna-Neyra A, Saenger P, Rodriguez-Buritica DF, Gamez Godoy JD, Muzumdar R, Amzel LM, Carrasco N: Sodium/Iodide Symporter Mutant V270E Causes Stunted Growth but No Cognitive Deficiency. J Clin Endocrinol Metab. 2015 Oct; 2015 Jul 23. PMID: 26204134

Guo X, Li Z, Zhang C, Yi Z, Li H, Cao L, Yuan C, Hong W, Wu Z, Peng D, Chen J, Xia W, Zhao G, Wang F, Yu S, Cui D, Xu Y, Golam CM, Smith AK, Wang T, Fang Y: Down-regulation of PRKCB1 expression in Han Chinese patients with subsyndromal symptomatic depression. J Psychiatr Res. 2015 Oct; 2015 Jul 17. PMID: 26343587

Heo JM, Ordureau A, Paulo JA, Rinehart J, Harper JW: The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy. Mol Cell. 2015 Oct 1; 2015 Sep 10. PMID: 26365381

Oza JP, Aerni HR, Pirman NL, Barber KW, ter Haar CM, Rogulina S, Amrofell MB, Isaacs FJ, Rinehart J, Jewett MC: Robust production of recombinant phosphoproteins using cell-free protein synthesis. Nat Commun. 2015 Sep 9; 2015 Sep 9. PMID: 26350765

Pirman NL, Barber KW, Aerni HR, Ma NJ, Haimovich AD, Rogulina S, Isaacs FJ, Rinehart J: A flexible codon in genomically recoded Escherichia coli permits programmable protein phosphorylation. Nat Commun. 2015 Sep 9; 2015 Sep 9. PMID: 26350500

Pluznick JL, Caplan MJ: Chemical and Physical Sensors in the Regulation of Renal Function. Clin J Am Soc Nephrol. 2015 Sep 4; 2014 Oct 3. PMID: 25280495

Bohn LM, Lohse MJ, Nitabach MN, Taghert PH, Smit MJ: Exploring the Biology of G Protein-Coupled Receptors from In Vitro to In Vivo. Mol Pharmacol. 2015 Sep; 2015 Jul 10. PMID: 26162863

Singh SK, Sigworth FJ: Cryo-EM: Spinning the Micelles Away. Structure. 2015 Sep 1. PMID: 26331455

Hoesl MG, Oehm S, Durkin P, Darmon E, Peil L, Aerni HR, Rappsilber J, Rinehart J, Leach D, Söll D, Budisa N: Chemical Evolution of a Bacterial Proteome. Angew Chem Int Ed Engl. 2015 Aug 17; 2015 Jul 1. PMID: 26136259

Bagriantsev SN, Gracheva EO: Molecular mechanisms of temperature adaptation. J Physiol. 2015 Aug 15; 2015 Jan 5. PMID: 25433072

Laplante C, Berro J, Karatekin E, Hernandez-Leyva A, Lee R, Pollard TD: Three myosins contribute uniquely to the assembly and constriction of the fission yeast cytokinetic contractile ring. Curr Biol. 2015 Aug 3; 2015 Jul 2. PMID: 26144970

Tagare HD, Kucukelbir A, Sigworth FJ, Wang H, Rao M: Directly reconstructing principal components of heterogeneous particles from cryo-EM images. J Struct Biol. 2015 Aug; 2015 Jun 4. PMID: 26049077

Graffe M, Zenisek D, Taraska JW: A marginal band of microtubules transports and organizes mitochondria in retinal bipolar synaptic terminals. J Gen Physiol. 2015 Jul. PMID: 26123197

Vucic E, Alfadda T, MacGregor GG, Dong K, Wang T, Geibel JP: Kir1.1 (ROMK) and Kv7.1 (KCNQ1/KvLQT1) are essential for normal gastric acid secretion: importance of functional Kir1.1. Pflugers Arch. 2015 Jul; 2014 Aug 17. PMID: 25127675

Corrie JE, Kaplan JH, Forbush B, Ogden DC, Trentham DR: Commentary on "Caged Phosphate and the Slips and Misses in Determination of Quantum Yields for Ultraviolet-A-Induced Photouncaging" by G. Gasser and Co-Workers. Chemphyschem. 2015 Jun 22; 2015 Feb 20. PMID: 25704071

Pedrozo Z, Criollo A, Battiprolu PK, Morales CR, Contreras-Ferrat A, Fernández C, Jiang N, Luo X, Caplan MJ, Somlo S, Rothermel BA, Gillette TG, Lavandero S, Hill JA: Polycystin-1 Is a Cardiomyocyte Mechanosensor That Governs L-Type Ca2+ Channel Protein Stability. Circulation. 2015 Jun 16; 2015 Apr 17. PMID: 25888683

Ravera S, Quick M, Nicola JP, Carrasco N, Amzel LM: Beyond non-integer Hill coefficients: A novel approach to analyzing binding data, applied to Na+-driven transporters. J Gen Physiol. 2015 Jun. PMID: 26009546

Ordureau A, Heo JM, Duda DM, Paulo JA, Olszewski JL, Yanishevski D, Rinehart J, Schulman BA, Harper JW: Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy. Proc Natl Acad Sci U S A. 2015 May 26; 2015 May 12. PMID: 25969509

Storace DA, Braubach OR, Jin L, Cohen LB, Sung U: Monitoring brain activity with protein voltage and calcium sensors. Sci Rep. 2015 May 13; 2015 May 13. PMID: 25970202

Dvornek NC, Sigworth FJ, Tagare HD: SubspaceEM: A fast maximum-a-posteriori algorithm for cryo-EM single particle reconstruction. J Struct Biol. 2015 May; 2015 Mar 31. PMID: 25839831

Du Z, Weinbaum S, Weinstein AM, Wang T: Regulation of glomerulotubular balance. III. Implication of cytosolic calcium in flow-dependent proximal tubule transport. Am J Physiol Renal Physiol. 2015 Apr 15; 2015 Jan 28. PMID: 25651568

Lin DH, Yue P, Yarborough O 3rd, Scholl UI, Giebisch G, Lifton RP, Rinehart J, Wang WH: Src-family protein tyrosine kinase phosphorylates WNK4 and modulates its inhibitory effect on KCNJ1 (ROMK). Proc Natl Acad Sci U S A. 2015 Apr 7; 2015 Mar 24. PMID: 25805816

González-Fernández R, Ávila J, Arteaga MF, Canessa CM, Martín-Vasallo P: The neuronal-specific SGK1.1 (SGK1_v2) kinase as a transcriptional modulator of BAG4, Brox, and PPP1CB genes expression. Int J Mol Sci. 2015 Apr 2; 2015 Apr 2. PMID: 25849655

Arriagada AA, Albornoz E, Opazo MC, Becerra A, Vidal G, Fardella C, Michea L, Carrasco N, Simon F, Elorza AA, Bueno SM, Kalergis AM, Riedel CA: Excess iodide induces an acute inhibition of the sodium/iodide symporter in thyroid male rat cells by increasing reactive oxygen species. Endocrinology. 2015 Apr; 2015 Jan 16. PMID: 25594695

Colangelo CM, Ivosev G, Chung L, Abbott T, Shifman M, Sakaue F, Cox D, Kitchen RR, Burton L, Tate SA, Gulcicek E, Bonner R, Rinehart J, Nairn AC, Williams KR: Development of a highly automated and multiplexed targeted proteome pipeline and assay for 112 rat brain synaptic proteins. Proteomics. 2015 Apr; 2015 Feb 12. PMID: 25476245

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Ilagan RP, Rhoades E, Gruber DF, Kao HT, Pieribone VA, Regan L: A new bright green-emitting fluorescent protein--engineered monomeric and dimeric forms. FEBS J. 2010 Apr; 2010 Mar 18. PMID: 20345907

Cu Y, LeMoëllic C, Caplan MJ, Saltzman WM: Ligand-modified gene carriers increased uptake in target cells but reduced DNA release and transfection efficiency. Nanomedicine. 2010 Apr; 2009 Oct 2. PMID: 19800989

Lu M, Dong K, Egan ME, Giebisch GH, Boulpaep EL, Hebert SC: Mouse cystic fibrosis transmembrane conductance regulator forms cAMP-PKA-regulated apical chloride channels in cortical collecting duct. Proc Natl Acad Sci U S A. 2010 Mar 30; 2010 Mar 15. PMID: 20231442

Gotoh N, Yan Q, Du Z, Biemesderfer D, Kashgarian M, Mooseker MS, Wang T: Altered renal proximal tubular endocytosis and histology in mice lacking myosin-VI. Cytoskeleton (Hoboken). 2010 Mar. PMID: 20175219

Karatekin E, Di Giovanni J, Iborra C, Coleman J, O'Shaughnessy B, Seagar M, Rothman JE: A fast, single-vesicle fusion assay mimics physiological SNARE requirements. Proc Natl Acad Sci U S A. 2010 Feb 23; 2010 Feb 2. PMID: 20133592

Cartiera MS, Ferreira EC, Caputo C, Egan ME, Caplan MJ, Saltzman WM: Partial correction of cystic fibrosis defects with PLGA nanoparticles encapsulating curcumin. Mol Pharm. 2010 Feb 1. PMID: 19886674

Tomita S: Regulation of ionotropic glutamate receptors by their auxiliary subunits. Physiology (Bethesda). 2010 Feb. PMID: 20134027

Kim KS, Yan D, Tomita S: Assembly and stoichiometry of the AMPA receptor and transmembrane AMPA receptor regulatory protein complex. J Neurosci. 2010 Jan 20. PMID: 20089915

Sigworth FJ, Doerschuk PC, Carazo JM, Scheres SH: An introduction to maximum-likelihood methods in cryo-EM. Methods Enzymol. 2010. PMID: 20888965

Wang L, Sigworth FJ: Liposomes on a streptavidin crystal: a system to study membrane proteins by cryo-EM. Methods Enzymol. 2010. PMID: 20887857

Homma R, Baker BJ, Jin L, Garaschuk O, Konnerth A, Cohen LB, Zecevic D: Wide-field and two-photon imaging of brain activity with voltage- and calcium-sensitive dyes. Philos Trans R Soc Lond B Biol Sci. 2009 Sep 12. PMID: 19651647

Wang L, Sigworth FJ: Structure of the BK potassium channel in a lipid membrane from electron cryomicroscopy. Nature. 2009 Sep 10; 2009 Aug 30. PMID: 19718020

Tanis JE, Bellemer A, Moresco JJ, Forbush B, Koelle MR: The potassium chloride cotransporter KCC-2 coordinates development of inhibitory neurotransmission and synapse structure in Caenorhabditis elegans. J Neurosci. 2009 Aug 12. PMID: 19675228

Rinehart J, Maksimova YD, Tanis JE, Stone KL, Hodson CA, Zhang J, Risinger M, Pan W, Wu D, Colangelo CM, Forbush B, Joiner CH, Gulcicek EE, Gallagher PG, Lifton RP: Sites of regulated phosphorylation that control K-Cl cotransporter activity. Cell. 2009 Aug 7. PMID: 19665974

Choi C, Fortin JP, McCarthy Ev, Oksman L, Kopin AS, Nitabach MN: Cellular dissection of circadian peptide signals with genetically encoded membrane-tethered ligands. Curr Biol. 2009 Jul 28; 2009 Jul 9. PMID: 19592252

Farr GA, Hull M, Mellman I, Caplan MJ: Membrane proteins follow multiple pathways to the basolateral cell surface in polarized epithelial cells. J Cell Biol. 2009 Jul 27; 2009 Jul 20. PMID: 19620635

Joselevitch C, Zenisek D: Imaging exocytosis in retinal bipolar cells with TIRF microscopy. J Vis Exp. 2009 Jun 9; 2009 Jun 9. PMID: 19513018

Snellman J, Zenisek D, Nawy S: Switching between transient and sustained signalling at the rod bipolar-AII amacrine cell synapse of the mouse retina. J Physiol. 2009 Jun 1; 2009 Mar 30. PMID: 19332496

Demento SL, Eisenbarth SC, Foellmer HG, Platt C, Caplan MJ, Mark Saltzman W, Mellman I, Ledizet M, Fikrig E, Flavell RA, Fahmy TM: Inflammasome-activating nanoparticles as modular systems for optimizing vaccine efficacy. Vaccine. 2009 May 18; 2009 Apr 3. PMID: 19428913

Cartiera MS, Johnson KM, Rajendran V, Caplan MJ, Saltzman WM: The uptake and intracellular fate of PLGA nanoparticles in epithelial cells. Biomaterials. 2009 May; 2009 Feb 20. PMID: 19232712

Coggins M, Zenisek D: Evidence that exocytosis is driven by calcium entry through multiple calcium channels in goldfish retinal bipolar cells. J Neurophysiol. 2009 May; 2009 Feb 25. PMID: 19244355

Homma R, Cohen LB, Kosmidis EK, Youngentob SL: Perceptual stability during dramatic changes in olfactory bulb activation maps and dramatic declines in activation amplitudes. Eur J Neurosci. 2009 Mar. PMID: 19291227

Li T, Yang Y, Canessa CM: Interaction of the aromatics Tyr-72/Trp-288 in the interface of the extracellular and transmembrane domains is essential for proton gating of acid-sensing ion channels. J Biol Chem. 2009 Feb 13; 2008 Dec 11. PMID: 19074149

Zhang W, St-Gelais F, Grabner CP, Trinidad JC, Sumioka A, Morimoto-Tomita M, Kim KS, Straub C, Burlingame AL, Howe JR, Tomita S: A transmembrane accessory subunit that modulates kainate-type glutamate receptors. Neuron. 2009 Feb 12. PMID: 19217376

Pluznick JL, Zou DJ, Zhang X, Yan Q, Rodriguez-Gil DJ, Eisner C, Wells E, Greer CA, Wang T, Firestein S, Schnermann J, Caplan MJ: Functional expression of the olfactory signaling system in the kidney. Proc Natl Acad Sci U S A. 2009 Feb 10; 2009 Jan 27. PMID: 19174512

Morimoto-Tomita M, Zhang W, Straub C, Cho CH, Kim KS, Howe JR, Tomita S: Autoinactivation of neuronal AMPA receptors via glutamate-regulated TARP interaction. Neuron. 2009 Jan 15. PMID: 19146816

Zhang L, Seo-Mayer P, Caplan MJ: Dystroglycan and AMP kinase: polarity's protectors when the power goes out. Dev Cell. 2009 Jan. PMID: 19154710

Chapin HC, Rajendran V, Capasso A, Caplan MJ: Detecting the surface localization and cytoplasmic cleavage of membrane-bound proteins. Methods Cell Biol. 2009; 2009 Dec 23. PMID: 20362093

Homma R, Baker BJ, Jin L, Garaschuk O, Konnerth A, Cohen LB, Bleau CX, Canepari M, Djurisic M, Zecevic D: Wide-field and two-photon imaging of brain activity with voltage- and calcium-sensitive dyes. Methods Mol Biol. 2009. PMID: 18839087

Wu Y, Cao G, Pavlicek B, Luo X, Nitabach MN: Phase coupling of a circadian neuropeptide with rest/activity rhythms detected using a membrane-tethered spider toxin. PLoS Biol. 2008 Nov 4. PMID: 18986214

Wang L, Ounjai P, Sigworth FJ: Streptavidin crystals as nanostructured supports and image-calibration references for cryo-EM data collection. J Struct Biol. 2008 Nov; 2008 Aug 5. PMID: 18707004

Wei F, Karihaloo A, Yu Z, Marlier A, Seth P, Shibazaki S, Wang T, Sukhatme VP, Somlo S, Cantley LG: Neutrophil gelatinase-associated lipocalin suppresses cyst growth by Pkd1 null cells in vitro and in vivo. Kidney Int. 2008 Nov; 2008 Aug 13. PMID: 18974761

Lal M, Song X, Pluznick JL, Di Giovanni V, Merrick DM, Rosenblum ND, Chauvet V, Gottardi CJ, Pei Y, Caplan MJ: Polycystin-1 C-terminal tail associates with beta-catenin and inhibits canonical Wnt signaling. Hum Mol Genet. 2008 Oct 15; 2008 Jul 16. PMID: 18632682

Coifman RR, Shkolnisky Y, Sigworth FJ, Singer A: Graph Laplacian tomography from unknown random projections. IEEE Trans Image Process. 2008 Oct. PMID: 18784036

Carmosino M, Giménez I, Caplan M, Forbush B: Exon loss accounts for differential sorting of Na-K-Cl cotransporters in polarized epithelial cells. Mol Biol Cell. 2008 Oct; 2008 Jul 30. PMID: 18667527

Yan Q, Yang X, Cantone A, Giebisch G, Hebert S, Wang T: Female ROMK null mice manifest more severe Bartter II phenotype on renal function and higher PGE2 production. Am J Physiol Regul Integr Comp Physiol. 2008 Sep; 2008 Jun 25. PMID: 18579648

Singh SK: LeuT: a prokaryotic stepping stone on the way to a eukaryotic neurotransmitter transporter structure. Channels (Austin). 2008 Sep-Oct. PMID: 19066470

Caplan MJ, Seo-Mayer P, Zhang L: Epithelial junctions and polarity: complexes and kinases. Curr Opin Nephrol Hypertens. 2008 Sep. PMID: 18695392

Huang KS, Carrasco N, Pfund E, Strobel SA: Transition state chirality and role of the vicinal hydroxyl in the ribosomal peptidyl transferase reaction. Biochemistry. 2008 Aug 26; 2008 Aug 2. PMID: 18672893

Duan Y, Gotoh N, Yan Q, Du Z, Weinstein AM, Wang T, Weinbaum S: Shear-induced reorganization of renal proximal tubule cell actin cytoskeleton and apical junctional complexes. Proc Natl Acad Sci U S A. 2008 Aug 12; 2008 Aug 6. PMID: 18685100

Baker BJ, Mutoh H, Dimitrov D, Akemann W, Perron A, Iwamoto Y, Jin L, Cohen LB, Isacoff EY, Pieribone VA, Hughes T, Knöpfel T: Genetically encoded fluorescent sensors of membrane potential. Brain Cell Biol. 2008 Aug; 2008 Aug 5. PMID: 18679801

Cao G, Nitabach MN: Circadian control of membrane excitability in Drosophila melanogaster lateral ventral clock neurons. J Neurosci. 2008 Jun 18. PMID: 18562620

Cantone A, Yang X, Yan Q, Giebisch G, Hebert SC, Wang T: Mouse model of type II Bartter's syndrome. I. Upregulation of thiazide-sensitive Na-Cl cotransport activity. Am J Physiol Renal Physiol. 2008 Jun; 2008 Apr 2. PMID: 18385266

Coric T, Passamaneck YJ, Zhang P, Di Gregorio A, Canessa CM: Simple chordates exhibit a proton-independent function of acid-sensing ion channels. FASEB J. 2008 Jun; 2008 Jan 22. PMID: 18211956

Fahmy TM, Demento SL, Caplan MJ, Mellman I, Saltzman WM: Design opportunities for actively targeted nanoparticle vaccines. Nanomedicine (Lond). 2008 Jun. PMID: 18510429

Harrisingh MC, Nitabach MN: Circadian rhythms. Integrating circadian timekeeping with cellular physiology. Science. 2008 May 16. PMID: 18487177

Wu Y, Cao G, Nitabach MN: Electrical silencing of PDF neurons advances the phase of non-PDF clock neurons in Drosophila. J Biol Rhythms. 2008 Apr. PMID: 18375861

Zenisek D: Vesicle association and exocytosis at ribbon and extraribbon sites in retinal bipolar cell presynaptic terminals. Proc Natl Acad Sci U S A. 2008 Mar 25; 2008 Mar 13. PMID: 18339810

Arteaga MF, Coric T, Straub C, Canessa CM: A brain-specific SGK1 splice isoform regulates expression of ASIC1 in neurons. Proc Natl Acad Sci U S A. 2008 Mar 18; 2008 Mar 11. PMID: 18334630

Pedersen M, Carmosino M, Forbush B: Intramolecular and intermolecular fluorescence resonance energy transfer in fluorescent protein-tagged Na-K-Cl cotransporter (NKCC1): sensitivity to regulatory conformational change and cell volume. J Biol Chem. 2008 Feb 1; 2007 Nov 28. PMID: 18045874

Nitabach MN, Taghert PH: Organization of the Drosophila circadian control circuit. Curr Biol. 2008 Jan 22. PMID: 18211849

Duffield A, Caplan MJ, Muth TR: Protein trafficking in polarized cells. Int Rev Cell Mol Biol. 2008. PMID: 19081536

Tomita S, Byrd RK, Rouach N, Bellone C, Venegas A, O'Brien JL, Kim KS, Olsen O, Nicoll RA, Bredt DS: AMPA receptors and stargazin-like transmembrane AMPA receptor-regulatory proteins mediate hippocampal kainate neurotoxicity. Proc Natl Acad Sci U S A. 2007 Nov 20; 2007 Nov 13. PMID: 18000041

Harrisingh MC, Wu Y, Lnenicka GA, Nitabach MN: Intracellular Ca2+ regulates free-running circadian clock oscillation in vivo. J Neurosci. 2007 Nov 14. PMID: 18003827

Sigworth FJ: The last few frames of the voltage-gating movie. Biophys J. 2007 Nov 1; 2007 Aug 17. PMID: 17704178

Coggins MR, Grabner CP, Almers W, Zenisek D: Stimulated exocytosis of endosomes in goldfish retinal bipolar neurons. J Physiol. 2007 Nov 1; 2007 Sep 6. PMID: 17823206

Kimura T, Allen PB, Nairn AC, Caplan MJ: Arrestins and spinophilin competitively regulate Na+,K+-ATPase trafficking through association with a large cytoplasmic loop of the Na+,K+-ATPase. Mol Biol Cell. 2007 Nov; 2007 Sep 5. PMID: 17804821

Stern E, Wagner R, Sigworth FJ, Breaker R, Fahmy TM, Reed MA: Importance of the Debye screening length on nanowire field effect transistor sensors. Nano Lett. 2007 Nov; 2007 Oct 3. PMID: 17914853

Kamsteeg EJ, Duffield AS, Konings IB, Spencer J, Pagel P, Deen PM, Caplan MJ: MAL decreases the internalization of the aquaporin-2 water channel. Proc Natl Acad Sci U S A. 2007 Oct 16; 2007 Oct 10. PMID: 17940053

Ounjai P, Unger VM, Sigworth FJ, Angsuthanasombat C: Two conformational states of the membrane-associated Bacillus thuringiensis Cry4Ba delta-endotoxin complex revealed by electron crystallography: implications for toxin-pore formation. Biochem Biophys Res Commun. 2007 Oct 5; 2007 Jul 25. PMID: 17681273

Cho CH, St-Gelais F, Zhang W, Tomita S, Howe JR: Two families of TARP isoforms that have distinct effects on the kinetic properties of AMPA receptors and synaptic currents. Neuron. 2007 Sep 20. PMID: 17880893

Zhang L, Caplan MJ: Transport protein sorting in polarized epithelial cells. Sheng Li Xue Bao. 2007 Aug 25. PMID: 17700970

Chester DW, Klemic JF, Stern E, Sigworth FJ, Klemic KG: Holey carbon micro-arrays for transmission electron microscopy: a microcontact printing approach. Ultramicroscopy. 2007 Aug; 2007 Jan 30. PMID: 17331648

Kocinsky HS, Dynia DW, Wang T, Aronson PS: NHE3 phosphorylation at serines 552 and 605 does not directly affect NHE3 activity. Am J Physiol Renal Physiol. 2007 Jul; 2007 Apr 4. PMID: 17409282

Caplan MJ, Kamsteeg EJ, Duffield A: Tetraspan proteins: regulators of renal structure and function. Curr Opin Nephrol Hypertens. 2007 Jul. PMID: 17565278

Caplan MJ: The future of the pump. J Clin Gastroenterol. 2007 Jul. PMID: 17575526

Arteaga MF, Alvarez de la Rosa D, Alvarez JA, Canessa CM: Multiple translational isoforms give functional specificity to serum- and glucocorticoid-induced kinase 1. Mol Biol Cell. 2007 Jun; 2007 Mar 21. PMID: 17377066

Baker BJ, Lee H, Pieribone VA, Cohen LB, Isacoff EY, Knopfel T, Kosmidis EK: Three fluorescent protein voltage sensors exhibit low plasma membrane expression in mammalian cells. J Neurosci Methods. 2007 Mar 30; 2006 Nov 28. PMID: 17126911

Nagayama S, Zeng S, Xiong W, Fletcher ML, Masurkar AV, Davis DJ, Pieribone VA, Chen WR: In vivo simultaneous tracing and Ca(2+) imaging of local neuronal circuits. Neuron. 2007 Mar 15. PMID: 17359915

Ring AM, Leng Q, Rinehart J, Wilson FH, Kahle KT, Hebert SC, Lifton RP: An SGK1 site in WNK4 regulates Na+ channel and K+ channel activity and has implications for aldosterone signaling and K+ homeostasis. Proc Natl Acad Sci U S A. 2007 Mar 6; 2007 Feb 22. PMID: 17360471

Ring AM, Cheng SX, Leng Q, Kahle KT, Rinehart J, Lalioti MD, Volkman HM, Wilson FH, Hebert SC, Lifton RP: WNK4 regulates activity of the epithelial Na+ channel in vitro and in vivo. Proc Natl Acad Sci U S A. 2007 Mar 6; 2007 Feb 26. PMID: 17360470

Giménez I, Forbush B: The residues determining differences in ion affinities among the alternative splice variants F, A, and B of the mammalian renal Na-K-Cl cotransporter (NKCC2). J Biol Chem. 2007 Mar 2; 2006 Dec 23. PMID: 17186942

Wang L, Bose PS, Sigworth FJ: Using cryo-EM to measure the dipole potential of a lipid membrane. Proc Natl Acad Sci U S A. 2006 Dec 5; 2006 Nov 20. PMID: 17116859

Zhang L, Li J, Young LH, Caplan MJ: AMP-activated protein kinase regulates the assembly of epithelial tight junctions. Proc Natl Acad Sci U S A. 2006 Nov 14; 2006 Nov 6. PMID: 17088526

Kahle KT, Rinehart J, Ring A, Gimenez I, Gamba G, Hebert SC, Lifton RP: WNK protein kinases modulate cellular Cl- flux by altering the phosphorylation state of the Na-K-Cl and K-Cl cotransporters. Physiology (Bethesda). 2006 Oct. PMID: 16990453

Wang T: Flow-activated transport events along the nephron. Curr Opin Nephrol Hypertens. 2006 Sep. PMID: 16914967

Yang B, Gribkoff VK, Pan J, Damagnez V, Dworetzky SI, Boissard CG, Bhattacharjee A, Yan Y, Sigworth FJ, Kaczmarek LK: Pharmacological activation and inhibition of Slack (Slo2.2) channels. Neuropharmacology. 2006 Sep; 2006 Jul 28. PMID: 16876206

Bourne J, Morgan JR, Pieribone VA: Actin polymerization regulates clathrin coat maturation during early stages of synaptic vesicle recycling at lamprey synapses. J Comp Neurol. 2006 Aug 1. PMID: 16739194

Arteaga MF, Wang L, Ravid T, Hochstrasser M, Canessa CM: An amphipathic helix targets serum and glucocorticoid-induced kinase 1 to the endoplasmic reticulum-associated ubiquitin-conjugation machinery. Proc Natl Acad Sci U S A. 2006 Jul 25; 2006 Jul 17. PMID: 16847254

Grabner C, Zenisek D: Rustling synaptic vesicle cargo after exocytosis. Neuron. 2006 Jul 6. PMID: 16815324

Li X, Klemic KG, Reed MA, Sigworth FJ: Microfluidic system for planar patch clamp electrode arrays. Nano Lett. 2006 Apr. PMID: 16608289

Lu M, Leng Q, Egan ME, Caplan MJ, Boulpaep EL, Giebisch GH, Hebert SC: CFTR is required for PKA-regulated ATP sensitivity of Kir1.1 potassium channels in mouse kidney. J Clin Invest. 2006 Mar; 2006 Feb 9. PMID: 16470247

Vucinić D, Cohen LB, Kosmidis EK: Interglomerular center-surround inhibition shapes odorant-evoked input to the mouse olfactory bulb in vivo. J Neurophysiol. 2006 Mar; 2005 Nov 30. PMID: 16319205

Leng Q, Kahle KT, Rinehart J, MacGregor GG, Wilson FH, Canessa CM, Lifton RP, Hebert SC: WNK3, a kinase related to genes mutated in hereditary hypertension with hyperkalaemia, regulates the K+ channel ROMK1 (Kir1.1). J Physiol. 2006 Mar 1; 2005 Dec 15. PMID: 16357011

Du Z, Yan Q, Duan Y, Weinbaum S, Weinstein AM, Wang T: Axial flow modulates proximal tubule NHE3 and H-ATPase activities by changing microvillus bending moments. Am J Physiol Renal Physiol. 2006 Feb; 2005 Sep 6. PMID: 16144961

Zhang P, Sigworth FJ, Canessa CM: Gating of acid-sensitive ion channel-1: release of Ca2+ block vs. allosteric mechanism. J Gen Physiol. 2006 Feb; 2006 Jan 17. PMID: 16418400

Wang L, Sigworth FJ: Cryo-EM and single particles. Physiology (Bethesda). 2006 Feb. PMID: 16443818

Grimm DH, Karihaloo A, Cai Y, Somlo S, Cantley LG, Caplan MJ: Polycystin-2 regulates proliferation and branching morphogenesis in kidney epithelial cells. J Biol Chem. 2006 Jan 6; 2005 Nov 8. PMID: 16278216

Rinehart J, Kahle KT, de Los Heros P, Vazquez N, Meade P, Wilson FH, Hebert SC, Gimenez I, Gamba G, Lifton RP: WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl- cotransporters required for normal blood pressure homeostasis. Proc Natl Acad Sci U S A. 2005 Nov 15; 2005 Nov 7. PMID: 16275913

Kahle KT, Rinehart J, de Los Heros P, Louvi A, Meade P, Vazquez N, Hebert SC, Gamba G, Gimenez I, Lifton RP: WNK3 modulates transport of Cl- in and out of cells: implications for control of cell volume and neuronal excitability. Proc Natl Acad Sci U S A. 2005 Nov 15; 2005 Nov 7. PMID: 16275911

Giraldez T, Hughes TE, Sigworth FJ: Generation of functional fluorescent BK channels by random insertion of GFP variants. J Gen Physiol. 2005 Nov. PMID: 16260837

Coric T, Zheng D, Gerstein M, Canessa CM: Proton sensitivity of ASIC1 appeared with the rise of fishes by changes of residues in the region that follows TM1 in the ectodomain of the channel. J Physiol. 2005 Nov 1; 2005 Jul 7. PMID: 16002453

Zatti A, Chauvet V, Rajendran V, Kimura T, Pagel P, Caplan MJ: The C-terminal tail of the polycystin-1 protein interacts with the Na,K-ATPase alpha-subunit. Mol Biol Cell. 2005 Nov; 2005 Aug 17. PMID: 16107561

Zochowski MR, Cohen LB: Oscillations in the olfactory bulb carry information about odorant history. J Neurophysiol. 2005 Oct; 2005 Jun 22. PMID: 15972833

Thomson RB, Wang T, Thomson BR, Tarrats L, Girardi A, Mentone S, Soleimani M, Kocher O, Aronson PS: Role of PDZK1 in membrane expression of renal brush border ion exchangers. Proc Natl Acad Sci U S A. 2005 Sep 13; 2005 Sep 2. PMID: 16141316

Prescott ED, Zenisek D: Recent progress towards understanding the synaptic ribbon. Curr Opin Neurobiol. 2005 Aug. PMID: 16023852

Arteaga MF, Canessa CM: Functional specificity of Sgk1 and Akt1 on ENaC activity. Am J Physiol Renal Physiol. 2005 Jul. PMID: 15951481

Zenisek D: Vesicle reuse revisited. Proc Natl Acad Sci U S A. 2005 May 24; 2005 May 17. PMID: 15899973

Merrifield CJ, Perrais D, Zenisek D: Coupling between clathrin-coated-pit invagination, cortactin recruitment, and membrane scission observed in live cells. Cell. 2005 May 20. PMID: 15907472

Baker BJ, Kosmidis EK, Vucinic D, Falk CX, Cohen LB, Djurisic M, Zecevic D: Imaging brain activity with voltage- and calcium-sensitive dyes. Cell Mol Neurobiol. 2005 Mar. PMID: 16050036

Rinehart J, Krett B, Rubio MA, Alfonzo JD, Söll D: Saccharomyces cerevisiae imports the cytosolic pathway for Gln-tRNA synthesis into the mitochondrion. Genes Dev. 2005 Mar 1; 2005 Feb 10. PMID: 15706032

Sigworth FJ, Klemic KG: Microchip technology in ion-channel research. IEEE Trans Nanobioscience. 2005 Mar. PMID: 15816178

Klemic KG, Klemic JF, Sigworth FJ: An air-molding technique for fabricating PDMS planar patch-clamp electrodes. Pflugers Arch. 2005 Mar; 2004 Dec 1. PMID: 15578213

Badou A, Basavappa S, Desai R, Peng YQ, Matza D, Mehal WZ, Kaczmarek LK, Boulpaep EL, Flavell RA: Requirement of voltage-gated calcium channel beta4 subunit for T lymphocyte functions. Science. 2005 Jan 7. PMID: 15637280

Mobasheri A, Barrett-Jolley R, Shakibaei M, Canessa CM, Martín-Vasallo P, Kamkin A, Kiseleva I: Enigmatic Roles of the Epithelial Sodium Channel (ENaC) in Articular Chondrocytes and Osteoblasts: Mechanotransduction, Sodium Transport or Extracellular Sodium Sensing? 2005. PMID: 21290775

Zhang YH, Alvarez de la Rosa D, Canessa CM, Hayslett JP: Insulin-induced phosphorylation of ENaC correlates with increased sodium channel function in A6 cells. Am J Physiol Cell Physiol. 2005 Jan; 2004 Sep 8. PMID: 15355850

Nitabach MN, Holmes TC, Blau J: Membranes, ions, and clocks: testing the Njus-Sulzman-Hastings model of the circadian oscillator. Methods Enzymol. 2005. PMID: 15817319

Bailey MA, Giebisch G, Abbiati T, Aronson PS, Gawenis LR, Shull GE, Wang T: NHE2-mediated bicarbonate reabsorption in the distal tubule of NHE3 null mice. J Physiol. 2004 Dec 15; 2004 Oct 7. PMID: 15604231

Zenisek D, Horst NK, Merrifield C, Sterling P, Matthews G: Visualizing synaptic ribbons in the living cell. J Neurosci. 2004 Nov 3. PMID: 15525760

Chauvet V, Tian X, Husson H, Grimm DH, Wang T, Hiesberger T, Igarashi P, Bennett AM, Ibraghimov-Beskrovnaya O, Somlo S, Caplan MJ: Mechanical stimuli induce cleavage and nuclear translocation of the polycystin-1 C terminus. J Clin Invest. 2004 Nov. PMID: 15545994

Kahle KT, Macgregor GG, Wilson FH, Van Hoek AN, Brown D, Ardito T, Kashgarian M, Giebisch G, Hebert SC, Boulpaep EL, Lifton RP: Paracellular Cl- permeability is regulated by WNK4 kinase: insight into normal physiology and hypertension. Proc Natl Acad Sci U S A. 2004 Oct 12; 2004 Oct 1. PMID: 15465913

Morgan JR, Di Paolo G, Werner H, Shchedrina VA, Pypaert M, Pieribone VA, De Camilli P: A role for talin in presynaptic function. J Cell Biol. 2004 Oct 11. PMID: 15479735

An S, Zenisek D: Regulation of exocytosis in neurons and neuroendocrine cells. Curr Opin Neurobiol. 2004 Oct. PMID: 15464884

Alvarez de la Rosa D, Paunescu TG, Els WJ, Helman SI, Canessa CM: Mechanisms of regulation of epithelial sodium channel by SGK1 in A6 cells. J Gen Physiol. 2004 Oct. PMID: 15452200

Du Z, Duan Y, Yan Q, Weinstein AM, Weinbaum S, Wang T: Mechanosensory function of microvilli of the kidney proximal tubule. Proc Natl Acad Sci U S A. 2004 Aug 31; 2004 Aug 19. PMID: 15319475

Yang Y, Yan Y, Sigworth FJ: Can Shaker potassium channels be locked in the deactivated state? J Gen Physiol. 2004 Aug. PMID: 15277577

Duffield A, Fölsch H, Mellman I, Caplan MJ: Sorting of H,K-ATPase beta-subunit in MDCK and LLC-PK cells is independent of mu 1B adaptin expression. Traffic. 2004 Jun. PMID: 15117319

Egan ME, Pearson M, Weiner SA, Rajendran V, Rubin D, Glöckner-Pagel J, Canny S, Du K, Lukacs GL, Caplan MJ: Curcumin, a major constituent of turmeric, corrects cystic fibrosis defects. Science. 2004 Apr 23. PMID: 15105504

Chen Y, Bourne J, Pieribone VA, Fitzsimonds RM: The role of actin in the regulation of dendritic spine morphology and bidirectional synaptic plasticity. Neuroreport. 2004 Apr 9. PMID: 15073524

Coric T, Hernandez N, Alvarez de la Rosa D, Shao D, Wang T, Canessa CM: Expression of ENaC and serum- and glucocorticoid-induced kinase 1 in the rat intestinal epithelium. Am J Physiol Gastrointest Liver Physiol. 2004 Apr; 2003 Nov 20. PMID: 14630642

Kuroda T, Bihler H, Bashi E, Slayman CL, Rivetta A: Chloride channel function in the yeast TRK-potassium transporters. J Membr Biol. 2004 Apr 1. PMID: 15216418

Lu M, Wang T, Yan Q, Wang W, Giebisch G, Hebert SC: ROMK is required for expression of the 70-pS K channel in the thick ascending limb. Am J Physiol Renal Physiol. 2004 Mar; 2003 Nov 4. PMID: 14600033

Kahle KT, Gimenez I, Hassan H, Wilson FH, Wong RD, Forbush B, Aronson PS, Lifton RP: WNK4 regulates apical and basolateral Cl- flux in extrarenal epithelia. Proc Natl Acad Sci U S A. 2004 Feb 17; 2004 Feb 9. PMID: 14769928

Zeng GF, Pypaert M, Slayman CL: Epitope tagging of the yeast K(+) carrier Trk2p demonstrates folding that is consistent with a channel-like structure. J Biol Chem. 2004 Jan 23; 2003 Oct 21. PMID: 14570869

Rinehart J, Horn EK, Wei D, Soll D, Schneider A: Non-canonical eukaryotic glutaminyl- and glutamyl-tRNA synthetases form mitochondrial aminoacyl-tRNA in Trypanosoma brucei. J Biol Chem. 2004 Jan 9; 2003 Oct 16. PMID: 14563839

Sigworth FJ: Classical detection theory and the cryo-EM particle selection problem. J Struct Biol. 2004 Jan-Feb. PMID: 15065679

Duffield A, Kamsteeg EJ, Brown AN, Pagel P, Caplan MJ: The tetraspanin CD63 enhances the internalization of the H,K-ATPase beta-subunit. Proc Natl Acad Sci U S A. 2003 Dec 23; 2003 Dec 5. PMID: 14660791

Bhattacharjee A, Joiner WJ, Wu M, Yang Y, Sigworth FJ, Kaczmarek LK: Slick (Slo2.1), a rapidly-gating sodium-activated potassium channel inhibited by ATP. J Neurosci. 2003 Dec 17. PMID: 14684870

Coric T, Zhang P, Todorovic N, Canessa CM: The extracellular domain determines the kinetics of desensitization in acid-sensitive ion channel 1. J Biol Chem. 2003 Nov 14; 2003 Aug 28. PMID: 12947112

Severson CA, Wang W, Pieribone VA, Dohle CI, Richerson GB: Midbrain serotonergic neurons are central pH chemoreceptors. Nat Neurosci. 2003 Nov; 2003 Sep 28. PMID: 14517544

Grimm DH, Cai Y, Chauvet V, Rajendran V, Zeltner R, Geng L, Avner ED, Sweeney W, Somlo S, Caplan MJ: Polycystin-1 distribution is modulated by polycystin-2 expression in mammalian cells. J Biol Chem. 2003 Sep 19; 2003 Jul 2. PMID: 12840011

Basavappa S, Mangel AW, Boulpaep EL: Calcium-dependent, swelling-activated K+ conductance in human neuroblastoma cells. Biochem Biophys Res Commun. 2003 Sep 5. PMID: 12927783

Wang T, Sterling H, Shao WA, Yan Q, Bailey MA, Giebisch G, Wang WH: Inhibition of heme oxygenase decreases sodium and fluid absorption in the loop of Henle. Am J Physiol Renal Physiol. 2003 Sep. PMID: 12890663

Alvarez de la Rosa D, Coric T, Todorovic N, Shao D, Wang T, Canessa CM: Distribution and regulation of expression of serum- and glucocorticoid-induced kinase-1 in the rat kidney. J Physiol. 2003 Sep 1; 2003 Jun 19. PMID: 12816971

Zecevic D, Djurisic M, Cohen LB, Antic S, Wachowiak M, Falk CX, Zochowski MR: Imaging nervous system activity with voltage-sensitive dyes. Curr Protoc Neurosci. 2003 Aug. PMID: 18428582

Dowd BF, Forbush B: PASK (proline-alanine-rich STE20-related kinase), a regulatory kinase of the Na-K-Cl cotransporter (NKCC1). J Biol Chem. 2003 Jul 25; 2003 May 9. PMID: 12740379

Giménez I, Forbush B: Short-term stimulation of the renal Na-K-Cl cotransporter (NKCC2) by vasopressin involves phosphorylation and membrane translocation of the protein. J Biol Chem. 2003 Jul 18; 2003 May 5. PMID: 12732642

Joiner WJ, Basavappa S, Vidyasagar S, Nehrke K, Krishnan S, Binder HJ, Boulpaep EL, Rajendran VM: Active K+ secretion through multiple KCa-type channels and regulation by IKCa channels in rat proximal colon. Am J Physiol Gastrointest Liver Physiol. 2003 Jul; 2003 Feb 26. PMID: 12606302

Bloom O, Evergren E, Tomilin N, Kjaerulff O, Löw P, Brodin L, Pieribone VA, Greengard P, Shupliakov O: Colocalization of synapsin and actin during synaptic vesicle recycling. J Cell Biol. 2003 May 26; 2003 May 19. PMID: 12756235

Du Z, Ferguson W, Wang T: Role of PKC and calcium in modulation of effects of angiotensin II on sodium transport in proximal tubule. Am J Physiol Renal Physiol. 2003 Apr; 2003 Jan 14. PMID: 12527554

Pagel P, Zatti A, Kimura T, Duffield A, Chauvet V, Rajendran V, Caplan MJ: Ion pump-interacting proteins: promising new partners. Ann N Y Acad Sci. 2003 Apr. PMID: 12763851

Zenisek D, Davila V, Wan L, Almers W: Imaging calcium entry sites and ribbon structures in two presynaptic cells. J Neurosci. 2003 Apr 1. PMID: 12684438

Wachowiak M, Cohen LB: Correspondence between odorant-evoked patterns of receptor neuron input and intrinsic optical signals in the mouse olfactory bulb. J Neurophysiol. 2003 Mar; 2002 Oct 23. PMID: 12612023

Alvarez de la Rosa D, Canessa CM: Role of SGK in hormonal regulation of epithelial sodium channel in A6 cells. Am J Physiol Cell Physiol. 2003 Feb; 2002 Oct 16. PMID: 12388075

Lam YW, Cohen LB, Zochowski MR: Odorant specificity of three oscillations and the DC signal in the turtle olfactory bulb. Eur J Neurosci. 2003 Feb. PMID: 12581162

Wang T: The effects of the potassium channel opener minoxidil on renal electrolytes transport in the loop of henle. J Pharmacol Exp Ther. 2003 Feb. PMID: 12538840

Alvarez de la Rosa D, Krueger SR, Kolar A, Shao D, Fitzsimonds RM, Canessa CM: Distribution, subcellular localization and ontogeny of ASIC1 in the mammalian central nervous system. J Physiol. 2003 Jan 1. PMID: 12509480

Djurisic M, Zochowski M, Wachowiak M, Falk CX, Cohen LB, Zecevic D: Optical monitoring of neural activity using voltage-sensitive dyes. Methods Enzymol. 2003. PMID: 12624923

Rosas-Sandoval G, Ambrogelly A, Rinehart J, Wei D, Cruz-Vera LR, Graham DE, Stetter KO, Guarneros G, Söll D: Orthologs of a novel archaeal and of the bacterial peptidyl-tRNA hydrolase are nonessential in yeast. Proc Natl Acad Sci U S A. 2002 Dec 24; 2002 Dec 10. PMID: 12475929

Pieribone VA, Porton B, Rendon B, Feng J, Greengard P, Kao HT: Expression of synapsin III in nerve terminals and neurogenic regions of the adult brain. J Comp Neurol. 2002 Dec 9. PMID: 12412137

Flemmer AW, Gimenez I, Dowd BF, Darman RB, Forbush B: Activation of the Na-K-Cl cotransporter NKCC1 detected with a phospho-specific antibody. J Biol Chem. 2002 Oct 4; 2002 Jul 26. PMID: 12145305

Darman RB, Forbush B: A regulatory locus of phosphorylation in the N terminus of the Na-K-Cl cotransporter, NKCC1. J Biol Chem. 2002 Oct 4; 2002 Jul 26. PMID: 12145304

Lu M, Wang T, Yan Q, Yang X, Dong K, Knepper MA, Wang W, Giebisch G, Shull GE, Hebert SC: Absence of small conductance K+ channel (SK) activity in apical membranes of thick ascending limb and cortical collecting duct in ROMK (Bartter's) knockout mice. J Biol Chem. 2002 Oct 4; 2002 Jul 18. PMID: 12130653

Wang T: Role of iNOS and eNOS in modulating proximal tubule transport and acid-base balance. Am J Physiol Renal Physiol. 2002 Oct. PMID: 12217856

Zhang P, Canessa CM: Single channel properties of rat acid-sensitive ion channel-1alpha, -2a, and -3 expressed in Xenopus oocytes. J Gen Physiol. 2002 Oct. PMID: 12356856

Wachowiak M, Cohen LB, Ache BW: Presynaptic inhibition of olfactory receptor neurons in crustaceans. Microsc Res Tech. 2002 Aug 15. PMID: 12214303

Mense M, Rajendran V, Blostein R, Caplan MJ: Extracellular domains, transmembrane segments, and intracellular domains interact to determine the cation selectivity of Na,K- and gastric H,K-ATPase. Biochemistry. 2002 Aug 6. PMID: 12146946

Jiang QX, Thrower EC, Chester DW, Ehrlich BE, Sigworth FJ: Three-dimensional structure of the type 1 inositol 1,4,5-trisphosphate receptor at 24 A resolution. EMBO J. 2002 Jul 15. PMID: 12110570

Sigworth FJ, Klemic KG: Patch clamp on a chip. Biophys J. 2002 Jun. PMID: 12023207

Klemic KG, Klemic JF, Reed MA, Sigworth FJ: Micromolded PDMS planar electrode allows patch clamp electrical recordings from cells. Biosens Bioelectron. 2002 Jun. PMID: 11959483

Alvarez de la Rosa D, Li H, Canessa CM: Effects of aldosterone on biosynthesis, traffic, and functional expression of epithelial sodium channels in A6 cells. J Gen Physiol. 2002 May. PMID: 11981022

Egan ME, Glöckner-Pagel J, Ambrose C, Cahill PA, Pappoe L, Balamuth N, Cho E, Canny S, Wagner CA, Geibel J, Caplan MJ: Calcium-pump inhibitors induce functional surface expression of Delta F508-CFTR protein in cystic fibrosis epithelial cells. Nat Med. 2002 May. PMID: 11984593

Bradley SR, Pieribone VA, Wang W, Severson CA, Jacobs RA, Richerson GB: Chemosensitive serotonergic neurons are closely associated with large medullary arteries. Nat Neurosci. 2002 May. PMID: 11967547

Giménez I, Isenring P, Forbush B: Spatially distributed alternative splice variants of the renal Na-K-Cl cotransporter exhibit dramatically different affinities for the transported ions. J Biol Chem. 2002 Mar 15; 2002 Jan 28. PMID: 11815599

Wang T, Giebisch G, Aronson PS: Use of transgenic animals to study renal acid-base transport. J Nephrol. 2002 Mar-Apr. PMID: 12027214

Alvarez de la Rosa D, Zhang P, Shao D, White F, Canessa CM: Functional implications of the localization and activity of acid-sensitive channels in rat peripheral nervous system. Proc Natl Acad Sci U S A. 2002 Feb 19; 2002 Feb 12. PMID: 11842212

Wachowiak M, Cohen LB, Zochowski MR: Distributed and concentration-invariant spatial representations of odorants by receptor neuron input to the turtle olfactory bulb. J Neurophysiol. 2002 Feb. PMID: 11826067

Ataka K, Pieribone VA: A genetically targetable fluorescent probe of channel gating with rapid kinetics. Biophys J. 2002 Jan. PMID: 11751337

Gu HH, Wu X, Giros B, Caron MG, Caplan MJ, Rudnick G: The NH(2)-terminus of norepinephrine transporter contains a basolateral localization signal for epithelial cells. Mol Biol Cell. 2001 Dec. PMID: 11739781

Wachowiak M, Cohen LB: Representation of odorants by receptor neuron input to the mouse olfactory bulb. Neuron. 2001 Nov 20. PMID: 11719211

Sigworth FJ: Potassium channel mechanics. Neuron. 2001 Nov 20. PMID: 11719196

Zheng J, Vankataramanan L, Sigworth FJ: Hidden Markov model analysis of intermediate gating steps associated with the pore gate of shaker potassium channels. J Gen Physiol. 2001 Nov. PMID: 11696611

Darman RB, Flemmer A, Forbush B: Modulation of ion transport by direct targeting of protein phosphatase type 1 to the Na-K-Cl cotransporter. J Biol Chem. 2001 Sep 14; 2001 Jul 20. PMID: 11466303

Dunbar LA, Caplan MJ: Ion pumps in polarized cells: sorting and regulation of the Na+, K+- and H+, K+-ATPases. J Biol Chem. 2001 Aug 10; 2001 Jun 12. PMID: 11404365

Singh SK, Mennone A, Gigliozzi A, Fraioli F, Boyer JL: Cl(-)-dependent secretory mechanisms in isolated rat bile duct epithelial units. Am J Physiol Gastrointest Liver Physiol. 2001 Aug. PMID: 11447024

Caplan MJ: Ion pump sorting in polarized renal epithelial cells. Kidney Int. 2001 Aug. PMID: 11473621

Zhang P, Canessa CM: Single-channel properties of recombinant acid-sensitive ion channels formed by the subunits ASIC2 and ASIC3 from dorsal root ganglion neurons expressed in Xenopus oocytes. J Gen Physiol. 2001 Jun. PMID: 11382806

McCarthy JB, Lim ST, Elkind NB, Trimmer JS, Duvoisin RM, Rodriguez-Boulan E, Caplan MJ: The C-terminal tail of the metabotropic glutamate receptor subtype 7 is necessary but not sufficient for cell surface delivery and polarized targeting in neurons and epithelia. J Biol Chem. 2001 Mar 23; 2000 Dec 5. PMID: 11106656

Jiang QX, Chester DW, Sigworth FJ: Spherical reconstruction: a method for structure determination of membrane proteins from cryo-EM images. J Struct Biol. 2001 Feb-Mar. PMID: 11472084

Ruan B, Ahel I, Ambrogelly A, Becker HD, Bunjun S, Feng L, Tumbula-Hansen D, Ibba M, Korencic D, Kobayashi H, Jacquin-Becker C, Mejlhede N, Min B, Raczniak G, Rinehart J, Stathopoulos C, Li T, Söll D: Genomics and the evolution of aminoacyl-tRNA synthesis. Acta Biochim Pol. 2001. PMID: 11732603

Robert ME, Singh SK, Ikuma M, Jain D, Ardito T, Binder HJ: Morphology of isolated colonic crypts. Cells Tissues Organs. 2001. PMID: 11275691

Stathopoulos C, Ahel I, Ali K, Ambrogelly A, Becker H, Bunjun S, Feng L, Herring S, Jacquin-Becker C, Kobayashi H, Korencic D, Krett B, Mejlhede N, Min B, Nakano H, Namgoong S, Polycarpo C, Raczniak G, Rinehart J, Rosas-Sandoval G, Ruan B, Sabina J, Sauerwald A, Toogood H, Tumbula-Hansen D, Ibba M, Söll D: Aminoacyl-tRNA synthesis: a postgenomic perspective. Cold Spring Harb Symp Quant Biol. 2001. PMID: 12762020

Islas LD, Sigworth FJ: Electrostatics and the gating pore of Shaker potassium channels. J Gen Physiol. 2001 Jan. PMID: 11134232

Zochowski M, Cohen LB, Fuhrmann G, Kleinfeld D: Distributed and partially separate pools of neurons are correlated with two different components of the gill-withdrawal reflex in Aplysia. J Neurosci. 2000 Nov 15. PMID: 11069956

Sangan P, Brill SR, Sangan S, Forbush B 3rd, Binder HJ: Basolateral K-Cl cotransporter regulates colonic potassium absorption in potassium depletion. J Biol Chem. 2000 Oct 6. PMID: 10878016

Wachowiak M, Zochowski M, Cohen LB, Falk CX: The spatial representation of odors by olfactory receptor neuron input to the olfactory bulb is concentration invariant. Biol Bull. 2000 Oct. PMID: 11081714

Gupta SS, Canessa CM: Heterologous expression of a mammalian epithelial sodium channel in yeast. FEBS Lett. 2000 Sep 8. PMID: 10984619

Dunbar LA, Caplan MJ: The cell biology of ion pumps: sorting and regulation. Eur J Cell Biol. 2000 Aug. PMID: 11001492

Choi I, Aalkjaer C, Boulpaep EL, Boron WF: An electroneutral sodium/bicarbonate cotransporter NBCn1 and associated sodium channel. Nature. 2000 Jun 1. PMID: 10850716

Dunbar LA, Aronson P, Caplan MJ: A transmembrane segment determines the steady-state localization of an ion-transporting adenosine triphosphatase. J Cell Biol. 2000 Feb 21. PMID: 10684257

Zochowski M, Wachowiak M, Falk CX, Cohen LB, Lam YW, Antic S, Zecevic D: Imaging membrane potential with voltage-sensitive dyes. Biol Bull. 2000 Feb. PMID: 10707808

Mense M, Dunbar LA, Blostein R, Caplan MJ: Residues of the fourth transmembrane segments of the Na,K-ATPase and the gastric H,K-ATPase contribute to cation selectivity. J Biol Chem. 2000 Jan 21. PMID: 10636871

Lam YW, Cohen LB, Wachowiak M, Zochowski MR: Odors elicit three different oscillations in the turtle olfactory bulb. J Neurosci. 2000 Jan 15. PMID: 10632604

Alvarez de la Rosa D, Canessa CM, Fyfe GK, Zhang P: Structure and regulation of amiloride-sensitive sodium channels. Annu Rev Physiol. 2000. PMID: 10845103

Alvarez de la Rosa D, Zhang P, Náray-Fejes-Tóth A, Fejes-Tóth G, Canessa CM: The serum and glucocorticoid kinase sgk increases the abundance of epithelial sodium channels in the plasma membrane of Xenopus oocytes. J Biol Chem. 1999 Dec 31. PMID: 10608847

Fyfe GK, Zhang P, Canessa CM: The second hydrophobic domain contributes to the kinetic properties of epithelial sodium channels. J Biol Chem. 1999 Dec 17. PMID: 10593937

Zhang P, Fyfe GK, Grichtchenko II, Canessa CM: Inhibition of alphabeta epithelial sodium channels by external protons indicates that the second hydrophobic domain contains structural elements for closing the pore. Biophys J. 1999 Dec. PMID: 10585926

Antic S, Cohen LB, Lam YW, Wachowiak M, Zecevic D, Zochowski M: Fast multisite optical measurement of membrane potential: three examples. FASEB J. 1999 Dec. PMID: 10619142

Islas LD, Sigworth FJ: Voltage sensitivity and gating charge in Shaker and Shab family potassium channels. J Gen Physiol. 1999 Nov. PMID: 10539976

Wachowiak M, Cohen LB: Presynaptic inhibition of primary olfactory afferents mediated by different mechanisms in lobster and turtle. J Neurosci. 1999 Oct 15. PMID: 10516300

Grishin AV, Reinhard J, Dunbar LA, Courtois-Coutry N, Wang T, Giebisch G, Caplan MJ: Nongastric H+,K+-ATPase: cell biologic and functional properties. Semin Nephrol. 1999 Sep. PMID: 10511382

Young LH, Russell RR 3rd, Yin R, Caplan MJ, Ren J, Bergeron R, Shulman GI, Sinusas AJ: Regulation of myocardial glucose uptake and transport during ischemia and energetic stress. Am J Cardiol. 1999 Jun 17. PMID: 10750583

Bihler H, Gaber RF, Slayman CL, Bertl A: The presumed potassium carrier Trk2p in Saccharomyces cerevisiae determines an H+-dependent, K+-independent current. FEBS Lett. 1999 Mar 19. PMID: 10218594

Gillen CM, Forbush B 3rd: Functional interaction of the K-Cl cotransporter (KCC1) with the Na-K-Cl cotransporter in HEK-293 cells. Am J Physiol. 1999 Feb. PMID: 9950760

Schmitt BM, Biemesderfer D, Romero MF, Boulpaep EL, Boron WF: Immunolocalization of the electrogenic Na+-HCO-3 cotransporter in mammalian and amphibian kidney. Am J Physiol. 1999 Jan. PMID: 9887077

Pieribone VA, Xu ZQ, Zhang X, Hökfelt T: Electrophysiologic effects of galanin on neurons of the central nervous system. Ann N Y Acad Sci. 1998 Dec 21. PMID: 9928177

Yang Y, Sigworth FJ: Single-channel properties of IKs potassium channels. J Gen Physiol. 1998 Dec. PMID: 9834139

Russell RR 3rd, Yin R, Caplan MJ, Hu X, Ren J, Shulman GI, Sinusas AJ, Young LH: Additive effects of hyperinsulinemia and ischemia on myocardial GLUT1 and GLUT4 translocation in vivo. Circulation. 1998 Nov 17. PMID: 9815873

Valentijn JA, Fyfe GK, Canessa CM: Biosynthesis and processing of epithelial sodium channels in Xenopus oocytes. J Biol Chem. 1998 Nov 13. PMID: 9804797

Wang T, Courtois-Coutry N, Giebisch G, Caplan MJ: A tyrosine-based signal regulates H-K-ATPase-mediated potassium reabsorption in the kidney. Am J Physiol. 1998 Nov. PMID: 9815140

Isenring P, Jacoby SC, Chang J, Forbush B: Mutagenic mapping of the Na-K-Cl cotransporter for domains involved in ion transport and bumetanide binding. J Gen Physiol. 1998 Nov. PMID: 9806964

Abdulnour-Nakhoul S, Boulpaep EL: Transcellular chloride pathways in ambystoma proximal tubule. J Membr Biol. 1998 Nov 1. PMID: 9784583

Grishin AV, Caplan MJ: ATP1AL1, a member of the non-gastric H,K-ATPase family, functions as a sodium pump. J Biol Chem. 1998 Oct 23. PMID: 9774385

Roush DL, Gottardi CJ, Naim HY, Roth MG, Caplan MJ: Tyrosine-based membrane protein sorting signals are differentially interpreted by polarized Madin-Darby canine kidney and LLC-PK1 epithelial cells. J Biol Chem. 1998 Oct 9. PMID: 9756932

Muth TR, Ahn J, Caplan MJ: Identification of sorting determinants in the C-terminal cytoplasmic tails of the gamma-aminobutyric acid transporters GAT-2 and GAT-3. J Biol Chem. 1998 Oct 2. PMID: 9748227

Zheng J, Sigworth FJ: Intermediate conductances during deactivation of heteromultimeric Shaker potassium channels. J Gen Physiol. 1998 Oct. PMID: 9758864

Fyfe GK, Canessa CM: Subunit composition determines the single channel kinetics of the epithelial sodium channel. J Gen Physiol. 1998 Oct. PMID: 9758861

Dunbar LA, Courtois-Coutry N, Roush DL, Muth TR, Gottardi CJ, Rajendran V, Geibel J, Kashgarian M, Caplan MJ: Sorting of P-type ATPases in polarized epithelial cells. Acta Physiol Scand Suppl. 1998 Aug. PMID: 9789572

Caplan MJ: Gastric H+/K(+)-ATPase: targeting signals in the regulation of physiologic function. Curr Opin Cell Biol. 1998 Aug. PMID: 9719867

Bihler H, Slayman CL, Bertl A: NSC1: a novel high-current inward rectifier for cations in the plasma membrane of Saccharomyces cerevisiae. FEBS Lett. 1998 Jul 31. PMID: 9710251

Isenring P, Jacoby SC, Forbush B 3rd: The role of transmembrane domain 2 in cation transport by the Na-K-Cl cotransporter. Proc Natl Acad Sci U S A. 1998 Jun 9. PMID: 9618559

Isenring P, Jacoby SC, Payne JA, Forbush B 3rd: Comparison of Na-K-Cl cotransporters. NKCC1, NKCC2, and the HEK cell Na-L-Cl cotransporter. J Biol Chem. 1998 May 1. PMID: 9556622

Shimkets RA, Lifton R, Canessa CM: In vivo phosphorylation of the epithelial sodium channel. Proc Natl Acad Sci U S A. 1998 Mar 17. PMID: 9501257

Muth TR, Gottardi CJ, Roush DL, Caplan MJ: A basolateral sorting signal is encoded in the alpha-subunit of Na-K-ATPase. Am J Physiol. 1998 Mar. PMID: 9530100

Fyfe GK, Quinn A, Canessa CM: Structure and function of the Mec-ENaC family of ion channels. Semin Nephrol. 1998 Mar. PMID: 9541269

Rajendran VM, Singh SK, Geibel J, Binder HJ: Differential localization of colonic H(+)-K(+)-ATPase isoforms in surface and crypt cells. Am J Physiol. 1998 Feb. PMID: 9486199

Schoppa NE, Sigworth FJ: Activation of Shaker potassium channels. III. An activation gating model for wild-type and V2 mutant channels. J Gen Physiol. 1998 Feb. PMID: 9450946

Schoppa NE, Sigworth FJ: Activation of Shaker potassium channels. II. Kinetics of the V2 mutant channel. J Gen Physiol. 1998 Feb. PMID: 9450945

Schoppa NE, Sigworth FJ: Activation of shaker potassium channels. I. Characterization of voltage-dependent transitions. J Gen Physiol. 1998 Feb. PMID: 9450944

Gu H, Caplan MJ, Rudnick G: Cloned catecholamine transporters expressed in polarized epithelial cells: sorting, drug sensitivity, and ion-coupling stoichiometry. Adv Pharmacol. 1998. PMID: 9327872

Mauerer UR, Boulpaep EL, Segal AS: Regulation of an inwardly rectifying ATP-sensitive K+ channel in the basolateral membrane of renal proximal tubule. J Gen Physiol. 1998 Jan. PMID: 9417142

Mauerer UR, Boulpaep EL, Segal AS: Properties of an inwardly rectifying ATP-sensitive K+ channel in the basolateral membrane of renal proximal tubule. J Gen Physiol. 1998 Jan. PMID: 9417141

Sigworth FJ: A maximum-likelihood approach to single-particle image refinement. J Struct Biol. 1998. PMID: 9774537

Ahn J, Pietrini G, Muth TR, Caplan MJ: Expression of neurotransmitter transport systems in polarized cells. Methods Enzymol. 1998. PMID: 9779461

Dunbar LA, Roush DL, Courtois-Coutry N, Muth TR, Gottardi CJ, Rajendran V, Geibel J, Kashgarian M, Caplan MJ: Sorting of ion pumps in polarized epithelial cells. Ann N Y Acad Sci. 1997 Nov 3. PMID: 9405853

Shimkets RA, Lifton RP, Canessa CM: The activity of the epithelial sodium channel is regulated by clathrin-mediated endocytosis. J Biol Chem. 1997 Oct 10. PMID: 9325269

Binder HJ, Singh SK, Geibel JP, Rajendran VM: Novel transport properties of colonic crypt cells: fluid absorption and Cl-dependent Na-H exchange. Comp Biochem Physiol A Physiol. 1997 Oct. PMID: 9366054

Isenring P, Forbush B 3rd: Ion and bumetanide binding by the Na-K-Cl cotransporter. Importance of transmembrane domains. J Biol Chem. 1997 Sep 26. PMID: 9305921

Muth TR, Dunbar LA, Cortois-Coutry N, Roush DL, Caplan MJ: Sorting and trafficking of ion transport proteins in polarized epithelial cells. Curr Opin Nephrol Hypertens. 1997 Sep. PMID: 9327204

Courtois-Coutry N, Roush D, Rajendran V, McCarthy JB, Geibel J, Kashgarian M, Caplan MJ: A tyrosine-based signal targets H/K-ATPase to a regulated compartment and is required for the cessation of gastric acid secretion. Cell. 1997 Aug 8. PMID: 9267030

Zheng J, Sigworth FJ: Selectivity changes during activation of mutant Shaker potassium channels. J Gen Physiol. 1997 Aug. PMID: 9236204

Boulpaep EL: Tubule electrophysiology: from single channels back to the renal epithelium. Wien Klin Wochenschr. 1997 Jun 27. PMID: 9261991

Boron WF, Fong P, Hediger MA, Boulpaep EL, Romero MF: The electrogenic Na/HCO3 cotransporter. Wien Klin Wochenschr. 1997 Jun 27. PMID: 9261985

Caplan MJ: Ion pumps in epithelial cells: sorting, stabilization, and polarity. Am J Physiol. 1997 Jun. PMID: 9227464

Yang Y, Yan Y, Sigworth FJ: How does the W434F mutation block current in Shaker potassium channels? J Gen Physiol. 1997 Jun. PMID: 9222903

McNicholas CM, Canessa CM: Diversity of channels generated by different combinations of epithelial sodium channel subunits. J Gen Physiol. 1997 Jun. PMID: 9222895

Ayer RK Jr, Sigworth FJ: Enhanced closed-state inactivation in a mutant Shaker K+ channel. J Membr Biol. 1997 Jun 1. PMID: 9178609

Romero MF, Hediger MA, Boulpaep EL, Boron WF: Expression cloning and characterization of a renal electrogenic Na+/HCO3- cotransporter. Nature. 1997 May 22. PMID: 9163427

Caplan MJ: Membrane polarity in epithelial cells: protein sorting and establishment of polarized domains. Am J Physiol. 1997 Apr. PMID: 9140041

Hickie C, Cohen LB, Balaban PM: The synapse between LE sensory neurons and gill motoneurons makes only a small contribution to the Aplysia gill-withdrawal reflex. Eur J Neurosci. 1997 Apr. PMID: 9153569

Mathur R, Zheng J, Yan Y, Sigworth FJ: Role of the S3-S4 linker in Shaker potassium channel activation. J Gen Physiol. 1997 Feb. PMID: 9041448

Boron VF, Hediger MA, Boulpaep EL, Romero MF: The renal electrogenic Na+:HCO-3 cotransporter. J Exp Biol. 1997 Jan. PMID: 9050234

Tsau Y, Wenner P, O'Donovan MJ, Cohen LB, Loew LM, Wuskell JP: Dye screening and signal-to-noise ratio for retrogradely transported voltage-sensitive dyes. J Neurosci Methods. 1996 Dec 28. PMID: 9007751

Caplan MJ: Sorting of GABA transporter proteins in polarized cells. Neurochem Int. 1996 Oct. PMID: 8939443

Brill SR, Ross KE, Davidow CJ, Ye M, Grantham JJ, Caplan MJ: Immunolocalization of ion transport proteins in human autosomal dominant polycystic kidney epithelial cells. Proc Natl Acad Sci U S A. 1996 Sep 17. PMID: 8816777

Grishin AV, Bevensee MO, Modyanov NN, Rajendran V, Boron WF, Caplan MJ: Functional expression of the cDNA encoded by the human ATP1AL1 gene. Am J Physiol. 1996 Sep. PMID: 8853415

Höpp HP, Falk CX, Cohen LB, Wu JY, Cohen AI: Effect of feedback from peripheral movements on neuron activity in the aplysia abdominal ganglion. Eur J Neurosci. 1996 Sep. PMID: 8921277

Gu HH, Ahn J, Caplan MJ, Blakely RD, Levey AI, Rudnick G: Cell-specific sorting of biogenic amine transporters expressed in epithelial cells. J Biol Chem. 1996 Jul 26. PMID: 8663573

Andreose JS, Fumagalli G, Sigworth FJ, Caplan MJ: Real-time detection of the surface delivery of newly synthesized membrane proteins. Proc Natl Acad Sci U S A. 1996 Jul 23. PMID: 8755532

Gillen CM, Brill S, Payne JA, Forbush B 3rd: Molecular cloning and functional expression of the K-Cl cotransporter from rabbit, rat, and human. A new member of the cation-chloride cotransporter family. J Biol Chem. 1996 Jul 5. PMID: 8663127

Cummins TR, Sigworth FJ: Impaired slow inactivation in mutant sodium channels. Biophys J. 1996 Jul. PMID: 8804606

Biemesderfer D, Payne JA, Lytle CY, Forbush B 3rd: Immunocytochemical studies of the Na-K-Cl cotransporter of shark kidney. Am J Physiol. 1996 Jun. PMID: 8764311

Segal AS, Boulpaep EL, Maunsbach AB: A novel preparation of dissociated renal proximal tubule cells that maintain epithelial polarity in suspension. Am J Physiol. 1996 Jun. PMID: 8764170

Yao X, Chang AY, Boulpaep EL, Segal AS, Desir GV: Molecular cloning of a glibenclamide-sensitive, voltage-gated potassium channel expressed in rabbit kidney. J Clin Invest. 1996 Jun 1. PMID: 8647945

Ahn J, Mundigl O, Muth TR, Rudnick G, Caplan MJ: Polarized expression of GABA transporters in Madin-Darby canine kidney cells and cultured hippocampal neurons. J Biol Chem. 1996 Mar 22. PMID: 8636119

Yao X, Segal AS, Welling P, Zhang X, McNicholas CM, Engel D, Boulpaep EL, Desir GV: Primary structure and functional expression of a cGMP-gated potassium channel. Proc Natl Acad Sci U S A. 1995 Dec 5. PMID: 8524834

Singh SK, Binder HJ, Geibel JP, Boron WF: An apical permeability barrier to NH3/NH4+ in isolated, perfused colonic crypts. Proc Natl Acad Sci U S A. 1995 Dec 5. PMID: 8524806

Lytle C, Xu JC, Biemesderfer D, Forbush B 3rd: Distribution and diversity of Na-K-Cl cotransport proteins: a study with monoclonal antibodies. Am J Physiol. 1995 Dec. PMID: 8572179

Sigworth FJ: Charge movement in the sodium channel. J Gen Physiol. 1995 Dec. PMID: 8786349

Singh SK, Binder HJ, Boron WF, Geibel JP: Fluid absorption in isolated perfused colonic crypts. J Clin Invest. 1995 Nov. PMID: 7593625

Canessa CM, Horisberger JD, Schild L, Rossier BC: Expression cloning of the epithelial sodium channel. Kidney Int. 1995 Oct. PMID: 8569104

Igarashi P, Vanden Heuvel GB, Payne JA, Forbush B 3rd: Cloning, embryonic expression, and alternative splicing of a murine kidney-specific Na-K-Cl cotransporter. Am J Physiol. 1995 Sep. PMID: 7573490

Quaggin SE, Payne JA, Forbush B 3rd, Igarashi P: Localization of the renal Na-K-Cl cotransporter gene (Slc12a1) on mouse chromosome 2. Mamm Genome. 1995 Aug. PMID: 8589530

Payne JA, Xu JC, Haas M, Lytle CY, Ward D, Forbush B 3rd: Primary structure, functional expression, and chromosomal localization of the bumetanide-sensitive Na-K-Cl cotransporter in human colon. J Biol Chem. 1995 Jul 28. PMID: 7629105

Shiel MJ, Caplan MJ: Developmental regulation of membrane protein sorting in Drosophila embryos. Am J Physiol. 1995 Jul. PMID: 7631747

Bertl A, Anderson JA, Slayman CL, Gaber RF: Use of Saccharomyces cerevisiae for patch-clamp analysis of heterologous membrane proteins: characterization of Kat1, an inward-rectifying K+ channel from Arabidopsis thaliana, and comparison with endogeneous yeast channels and carriers. Proc Natl Acad Sci U S A. 1995 Mar 28. PMID: 7708709

Gottardi CJ, Dunbar LA, Caplan MJ: Biotinylation and assessment of membrane polarity: caveats and methodological concerns. Am J Physiol. 1995 Feb. PMID: 7864168

Sigworth FJ, Affolter H, Neher E: Design of the EPC-9, a computer-controlled patch-clamp amplifier. 2. Software. J Neurosci Methods. 1995 Feb. PMID: 7538621

SIGWorth FJ: Design of the EPC-9, a computer-controlled patch-clamp amplifier. 1. Hardware. J Neurosci Methods. 1995 Feb. PMID: 7538620

Slayman CL, Moussatos VV, Webb WW: Endosomal accumulation of pH indicator dyes delivered as acetoxymethyl esters. J Exp Biol. 1994 Nov. PMID: 7823037

Slayman CL: Metamorphosis of research on ion-coupled metabolite transport. J Exp Biol. 1994 Nov. PMID: 7823017

Roush DL, Gottardi CJ, Caplan MJ: Sorting of the gastric H,K-ATPase in endocrine and epithelial cells. Ann N Y Acad Sci. 1994 Sep 15. PMID: 7978870

Jiang C, Sigworth FJ, Haddad GG: Oxygen deprivation activates an ATP-inhibitable K+ channel in substantia nigra neurons. J Neurosci. 1994 Sep. PMID: 8083755

Tsau Y, Wu JY, Höpp HP, Cohen LB, Schiminovich D, Falk CX: Distributed aspects of the response to siphon touch in Aplysia: spread of stimulus information and cross-correlation analysis. J Neurosci. 1994 Jul. PMID: 8027769

Payne JA, Forbush B 3rd: Alternatively spliced isoforms of the putative renal Na-K-Cl cotransporter are differentially distributed within the rabbit kidney. Proc Natl Acad Sci U S A. 1994 May 10. PMID: 7514306

Forbush B 3rd, Lytle C, Xu JC, Payne JA, Biemesderfer D: The Na, K, C cotransporter of shark rectal gland. Ren Physiol Biochem. 1994 May-Aug. PMID: 7518959

Xu JC, Lytle C, Zhu TT, Payne JA, Benz E Jr, Forbush B 3rd: Molecular cloning and functional expression of the bumetanide-sensitive Na-K-Cl cotransporter. Proc Natl Acad Sci U S A. 1994 Mar 15. PMID: 8134373

Wu JY, Tsau Y, Hopp HP, Cohen LB, Tang AC, Falk CX: Consistency in nervous systems: trial-to-trial and animal-to-animal variations in the responses to repeated applications of a sensory stimulus in Aplysia. J Neurosci. 1994 Mar. PMID: 8120632

Slayman CL, Kuroda H, Ballarin-Denti A: Cation effluxes associated with the uptake of TPP+, TPA+, and TPMP+ by Neurospora: evidence for a predominantly electroneutral influx process. Biochim Biophys Acta. 1994 Feb 23. PMID: 8110821

Ballarin-Denti A, Slayman CL, Kuroda H: Small lipid-soluble cations are not membrane voltage probes for Neurospora or Saccharomyces. Biochim Biophys Acta. 1994 Feb 23. PMID: 8110820

Pietrini G, Suh YJ, Edelmann L, Rudnick G, Caplan MJ: The axonal gamma-aminobutyric acid transporter GAT-1 is sorted to the apical membranes of polarized epithelial cells. J Biol Chem. 1994 Feb 11. PMID: 8308038

Wu JY, Cohen LB, Falk CX: Neuronal activity during different behaviors in Aplysia: a distributed organization? Science. 1994 Feb 11. PMID: 8303300

Sigworth FJ: Voltage gating of ion channels. Q Rev Biophys. 1994 Feb. PMID: 7520590

Bertl A, Anderson JA, Slayman CL, Sentenac H, Gaber RF: Inward and outward rectifying potassium currents in Saccharomyces cerevisiae mediated by endogenous and heterelogously expressed ion channels. Folia Microbiol (Praha). 1994. PMID: 8550001

Slayman CL, Bertl A: Modes and means of channel behavior: an introduction. Symp Soc Exp Biol. 1994. PMID: 7541164

Cascio M, Schoppa NE, Grodzicki RL, Sigworth FJ, Fox RO: Functional expression and purification of a homomeric human alpha 1 glycine receptor in baculovirus-infected insect cells. J Biol Chem. 1993 Oct 15. PMID: 8408073

McCormack K, Lin L, Sigworth FJ: Substitution of a hydrophobic residue alters the conformational stability of Shaker K+ channels during gating and assembly. Biophys J. 1993 Oct. PMID: 8274662

Korbmacher C, Segal AS, Fejes-Tóth G, Giebisch G, Boulpaep EL: Whole-cell currents in single and confluent M-1 mouse cortical collecting duct cells. J Gen Physiol. 1993 Oct. PMID: 8270912

Falk CX, Wu JY, Cohen LB, Tang AC: Nonuniform expression of habituation in the activity of distinct classes of neurons in the Aplysia abdominal ganglion. J Neurosci. 1993 Sep. PMID: 8366360

Korbmacher C, Boulpaep EL, Giebisch G, Geibel J: Endothelin increases [Ca2+]i in M-1 mouse cortical collecting duct cells by a dual mechanism. Am J Physiol. 1993 Aug. PMID: 8368264

Gottardi CJ, Caplan MJ: Molecular requirements for the cell-surface expression of multisubunit ion-transporting ATPases. Identification of protein domains that participate in Na,K-ATPase and H,K-ATPase subunit assembly. J Biol Chem. 1993 Jul 5. PMID: 8390991

Gottardi CJ, Caplan MJ: An ion-transporting ATPase encodes multiple apical localization signals. J Cell Biol. 1993 Apr. PMID: 8385670

Cummins TR, Zhou J, Sigworth FJ, Ukomadu C, Stephan M, Ptácek LJ, Agnew WS: Functional consequences of a Na+ channel mutation causing hyperkalemic periodic paralysis. Neuron. 1993 Apr. PMID: 8386527

Bertl A, Slayman CL, Gradmann D: Gating and conductance in an outward-rectifying K+ channel from the plasma membrane of Saccharomyces cerevisiae. J Membr Biol. 1993 Mar. PMID: 8492306

Crouzy SC, Sigworth FJ: Fluctuations in ion channel gating currents. Analysis of nonstationary shot noise. Biophys J. 1993 Jan. PMID: 8381683

Gottardi CJ, Pietrini G, Roush DL, Caplan MJ: Sorting of ion transport proteins in polarized cells. J Cell Sci Suppl. 1993. PMID: 8144688

Lytle C, Xu JC, Biemesderfer D, Haas M, Forbush B 3rd: The Na-K-Cl cotransport protein of shark rectal gland. I. Development of monoclonal antibodies, immunoaffinity purification, and partial biochemical characterization. J Biol Chem. 1992 Dec 15. PMID: 1460038

Lytle C, Forbush B 3rd: The Na-K-Cl cotransport protein of shark rectal gland. II. Regulation by direct phosphorylation. J Biol Chem. 1992 Dec 15. PMID: 1334094

McCormack K, Lin L, Iverson LE, Tanouye MA, Sigworth FJ: Tandem linkage of Shaker K+ channel subunits does not ensure the stoichiometry of expressed channels. Biophys J. 1992 Nov. PMID: 1477286

Bertl A, Slayman CL: Complex modulation of cation channels in the tonoplast and plasma membrane of Saccharomyces cerevisiae: single-channel studies. J Exp Biol. 1992 Nov. PMID: 1283402

Slayman CL: Some remarks on the integrated actions of pumps, cotransporters and channels. J Exp Biol. 1992 Nov. PMID: 1283401

Ahmad I, Korbmacher C, Segal AS, Cheung P, Boulpaep EL, Barnstable CJ: Mouse cortical collecting duct cells show nonselective cation channel activity and express a gene related to the cGMP-gated rod photoreceptor channel. Proc Natl Acad Sci U S A. 1992 Nov 1. PMID: 1279673

Bertl A, Gradmann D, Slayman CL: Calcium- and voltage-dependent ion channels in Saccharomyces cerevisiae. Philos Trans R Soc Lond B Biol Sci. 1992 Oct 29. PMID: 1280839

Pietrini G, Matteoli M, Banker G, Caplan MJ: Isoforms of the Na,K-ATPase are present in both axons and dendrites of hippocampal neurons in culture. Proc Natl Acad Sci U S A. 1992 Sep 15. PMID: 1326755

Spalding EP, Slayman CL, Goldsmith MH, Gradmann D, Bertl A: Ion channels in Arabidopsis plasma membrane : transport characteristics and involvement in light-induced voltage changes. Plant Physiol. 1992 May. PMID: 16668890

Ukomadu C, Zhou J, Sigworth FJ, Agnew WS: muI Na+ channels expressed transiently in human embryonic kidney cells: biochemical and biophysical properties. Neuron. 1992 Apr. PMID: 1314619

Schoppa NE, McCormack K, Tanouye MA, Sigworth FJ: The size of gating charge in wild-type and mutant Shaker potassium channels. Science. 1992 Mar 27. PMID: 1553560

Slayman CL: Molecular correlates of physiological regulation in a P-type H(+)-ATPase. Acta Physiol Scand Suppl. 1992. PMID: 1449060

Zhou JY, Potts JF, Trimmer JS, Agnew WS, Sigworth FJ: Multiple gating modes and the effect of modulating factors on the microI sodium channel. Neuron. 1991 Nov. PMID: 1660285

Boll W, Partin JS, Katz AI, Caplan MJ, Jamieson JD: Distinct pathways for basolateral targeting of membrane and secretory proteins in polarized epithelial cells. Proc Natl Acad Sci U S A. 1991 Oct 1. PMID: 1656451

Shenkel S, Sigworth FJ: Patch recordings from the electrocytes of Electrophorus electricus. Na currents and PNa/PK variability. J Gen Physiol. 1991 May. PMID: 1650809

Forbush B 3rd, Klodos I: Rate-limiting steps in Na translocation by the Na/K pump. Soc Gen Physiol Ser. 1991. PMID: 1653981

Bock JF, Boulpaep EL: Bicarbonate transport mechanisms in the Ambystoma kidney proximal tubule: transepithelial potential measurements. Yale J Biol Med. 1990 Nov-Dec. PMID: 2092412

Bertl A, Slayman CL: Cation-selective channels in the vacuolar membrane of Saccharomyces: dependence on calcium, redox state, and voltage. Proc Natl Acad Sci U S A. 1990 Oct. PMID: 1700419

Crouzy SC, Sigworth FJ: Yet another approach to the dwell-time omission problem of single-channel analysis. Biophys J. 1990 Sep. PMID: 1698473

Sine SM, Claudio T, Sigworth FJ: Activation of Torpedo acetylcholine receptors expressed in mouse fibroblasts. Single channel current kinetics reveal distinct agonist binding affinities. J Gen Physiol. 1990 Aug. PMID: 1698917

Caplan MJ, Forbush B 3rd, Palade GE, Jamieson JD: Biosynthesis of the Na,K-ATPase in Madin-Darby canine kidney cells. Activation and cell surface delivery. J Biol Chem. 1990 Feb 25. PMID: 2154482

Shenkel S, Cooper EC, James W, Agnew WS, Sigworth FJ: Purified, modified eel sodium channels are active in planar bilayers in the absence of activating neurotoxins. Proc Natl Acad Sci U S A. 1989 Dec. PMID: 2556720

Zecević D, Wu JY, Cohen LB, London JA, Höpp HP, Falk CX: Hundreds of neurons in the Aplysia abdominal ganglion are active during the gill-withdrawal reflex. J Neurosci. 1989 Oct. PMID: 2795148

Boron WF, Boulpaep EL: The electrogenic Na/HCO3 cotransporter. Kidney Int. 1989 Sep. PMID: 2687566

Trimmer JS, Cooperman SS, Tomiko SA, Zhou JY, Crean SM, Boyle MB, Kallen RG, Sheng ZH, Barchi RL, Sigworth FJ: Primary structure and functional expression of a mammalian skeletal muscle sodium channel. Neuron. 1989 Jul. PMID: 2559760

London JA, Cohen LB, Wu JY: Optical recordings of the cortical response to whisker stimulation before and after the addition of an epileptogenic agent. J Neurosci. 1989 Jun. PMID: 2723769

Slayman CL, Zuckier GR: Differential function properties of a P-type ATPase/proton pump. Ann N Y Acad Sci. 1989. PMID: 2561321

Heinemann SH, Sigworth FJ: Open channel noise. IV. Estimation of rapid kinetics of formamide block in gramicidin A channels. Biophys J. 1988 Oct. PMID: 2465033

Tripathi S, Boulpaep EL: Cell membrane water permeabilities and streaming currents in Ambystoma proximal tubule. Am J Physiol. 1988 Jul. PMID: 3394810

Forbush B 3rd: The interaction of amines with the occluded state of the Na,K-pump. J Biol Chem. 1988 Jun 15. PMID: 2836405

Forbush B 3rd: Rapid release of 45Ca from an occluded state of the Na,K-pump. J Biol Chem. 1988 Jun 15. PMID: 2836404

Forbush B 3rd: Rapid 86Rb release from an occluded state of the Na,K-pump reflects the rate of dephosphorylation or dearsenylation. J Biol Chem. 1988 Jun 15. PMID: 2836403

Wu JY, London JA, Zecevic D, Höpp HP, Cohen LB, Xiao C: Optical monitoring of activity of many neurons in invertebrate ganglia during behaviors. Experientia. 1988 May 15. PMID: 3286282

Haas M, Forbush B 3rd: Photoaffinity labelling of a 150 kDa (Na + K + Cl)-cotransport protein from duck red cells with an analog of bumetanide. Biochim Biophys Acta. 1988 Mar 22. PMID: 3349075

Smith ZD, Caplan MJ, Jamieson JD: Immunocytochemical localization of plasmalemmal proteins in semi-thin sections of epithelial monolayers. J Histochem Cytochem. 1988 Mar. PMID: 2449492

Halevy J, Boulpaep EL, Budinger ME, Binder HJ, Hayslett JP: Glucocorticoids have a different action than aldosterone on target tissue. Am J Physiol. 1988 Jan. PMID: 3337244

Caplan MJ, Anderson HC, Palade GE, Jamieson JD: Sorting of newly synthesized Na,K-ATPase in polarized epithelial cells. Prog Clin Biol Res. 1988. PMID: 2851829

Forbush B 3rd: Overview: occluded ions and Na, K-ATPase. Prog Clin Biol Res. 1988. PMID: 2843866

Claudio T, Green WN, Hartman DS, Hayden D, Paulson HL, Sigworth FJ, Sine SM, Swedlund A: Genetic reconstitution of functional acetylcholine receptor channels in mouse fibroblasts. Science. 1987 Dec 18. PMID: 3686008

Sigworth FJ, Urry DW, Prasad KU: Open channel noise. III. High-resolution recordings show rapid current fluctuations in gramicidin A and four chemical analogues. Biophys J. 1987 Dec. PMID: 2447969

Sigworth FJ, Sine SM: Data transformations for improved display and fitting of single-channel dwell time histograms. Biophys J. 1987 Dec. PMID: 2447968

Haas M, Forbush B 3rd: Na,K,Cl-cotransport system: characterization by bumetanide binding and photolabelling. Kidney Int Suppl. 1987 Dec. PMID: 3481640

Caplan MJ, Stow JL, Newman AP, Madri J, Anderson HC, Farquhar MG, Palade GE, Jamieson JD: Dependence on pH of polarized sorting of secreted proteins. Nature. 1987 Oct 15-21. PMID: 2821405

Steels PS, Boulpaep EL: pH-dependent electrical properties and buffer permeability of the Necturus renal proximal tubule cell. J Membr Biol. 1987. PMID: 3430572

Blatt MR, Rodriguez-Navarro A, Slayman CL: Potassium-proton symport in Neurospora: kinetic control by pH and membrane potential. J Membr Biol. 1987. PMID: 2959789