Publications
Showing 1 - 100 results of 6,027 publications
2025
- L-type calcium channel blockade attenuates the anxiogenic-like effects of cocaine abstinence in female and male rats.Nunes EJ, Kimble V, Rajadhyaksha AM, Addy NA. L-type calcium channel blockade attenuates the anxiogenic-like effects of cocaine abstinence in female and male rats. Neuroscience 2025, 568: 314-322. PMID: 39761823, DOI: 10.1016/j.neuroscience.2025.01.003.
- Engineering a genomically recoded organism with one stop codon.Grome MW, Nguyen MTA, Moonan DW, Mohler K, Gurara K, Wang S, Hemez C, Stenton BJ, Cao Y, Radford F, Kornaj M, Patel J, Prome M, Rogulina S, Sozanski D, Tordoff J, Rinehart J, Isaacs FJ. Engineering a genomically recoded organism with one stop codon. Nature 2025, 639: 512-521. PMID: 39910296, DOI: 10.1038/s41586-024-08501-x.
- Engineering a genomically recoded organism with one stop codonGrome MW, Nguyen MTA, Moonan DW, Mohler K, Gurara K, Wang S, Hemez C, Stenton BJ, Cao Y, Radford F, Kornaj M, Patel J, Prome M, Rogulina S, Sozanski D, Tordoff J, Rinehart J, Isaacs FJ. Engineering a genomically recoded organism with one stop codon. Nature. 2025. doi: 10.1038/s41586-024-08501-x. Online Feb 5
- Structural basis for human NKCC1 inhibition by loop diuretic drugsZho Y, Vidossich P, Forbush B, Ma J, Rinehart J, De Vivo M, Cao E. Structural basis for human NKCC1 inhibition by loop diuretic drugs. EMBO J. 2025. doi 10.1038/s44318-025-00368-6. Online January 28.
- The other side of the incretin story: GIPR signaling in energy homeostasis.Nakandakari SCBR, Fosam AE, Perry RJ. The other side of the incretin story: GIPR signaling in energy homeostasis. Cell Metab 2025, 37: 1-3. PMID: 39778517, DOI: 10.1016/j.cmet.2024.12.003.
- Metabolic rewiring in skin epidermis drives tolerance to oncogenic mutations.Hemalatha A, Li Z, Gonzalez DG, Matte-Martone C, Tai K, Lathrop E, Gil D, Ganesan S, Gonzalez LE, Skala M, Perry RJ, Greco V. Metabolic rewiring in skin epidermis drives tolerance to oncogenic mutations. Nat Cell Biol 2025 PMID: 39762578, DOI: 10.1038/s41556-024-01574-w.
- Systematic review and meta-analysis of the genetics of peripheral arterial diseaseChaar C, Kim T, Alameddine D, DeWan A, Guzman R, Dardik A, Nardini H, Wallach J, Kullo I, Murray M. Systematic review and meta-analysis of the genetics of peripheral arterial disease. Journal Of Vascular Surgery 2025, 81: a13-a14. DOI: 10.1016/j.jvs.2024.10.063.
2024
- Vesicle docking and fusion pore modulation by the neuronal calcium sensor Synaptotagmin-1.Tsemperouli M, Cheppali SK, Rivera-Molina F, Chetrit D, Landajuela A, Toomre D, Karatekin E. Vesicle docking and fusion pore modulation by the neuronal calcium sensor Synaptotagmin-1. Biophys J 2024 PMID: 39719826, DOI: 10.1016/j.bpj.2024.12.023.
- Periodic ER-plasma membrane junctions support long-range Ca2+ signal integration in dendritesBenedetti L, Fan R, Weigel A, Moore A, Houlihan P, Kittisopikul M, Park G, Petruncio A, Hubbard P, Pang S, Xu C, Hess H, Saalfeld S, Rangaraju V, Clapham D, De Camilli P, Ryan T, Lippincott-Schwartz J. Periodic ER-plasma membrane junctions support long-range Ca2+ signal integration in dendrites. Cell 2024, 188: 484-500.e22. PMID: 39708809, DOI: 10.1016/j.cell.2024.11.029.
- Distinct mechanisms drive divergent phenotypes in hypertrophic and dilated cardiomyopathy associated TPM1 variantsHalder S, Rynkiewicz M, Kim L, Barry M, Zied A, Sewanan L, Kirk J, Moore J, Lehman W, Campbell S. Distinct mechanisms drive divergent phenotypes in hypertrophic and dilated cardiomyopathy associated TPM1 variants. Journal Of Clinical Investigation 2024, 134: e179135. PMID: 39436707, PMCID: PMC11645150, DOI: 10.1172/jci179135.
- SGLT2 inhibition alters substrate utilization and mitochondrial redox in healthy and failing rat heartsGoedeke L, Ma Y, Gaspar R, Nasiri A, Lee J, Zhang D, Galsgaard K, Hu X, Zhang J, Guerrera N, Li X, LaMoia T, Hubbard B, Haedersdal S, Wu X, Stack J, Dufour S, Butrico G, Kahn M, Perry R, Cline G, Young L, Shulman G. SGLT2 inhibition alters substrate utilization and mitochondrial redox in healthy and failing rat hearts. Journal Of Clinical Investigation 2024, 134: e176708. PMID: 39680452, PMCID: PMC11645152, DOI: 10.1172/jci176708.
- Biodistribution of Polymeric Nanoparticles following In-Utero Delivery to a Non-Human PrimateEaton D, Lynn A, Surprenant J, Deschenes E, Guerra M, Rivero R, Yung N, O'Connor M, Glazer P, Bahtiyar M, Saltzman W, Stitelman D. Biodistribution of Polymeric Nanoparticles following In-Utero Delivery to a Non-Human Primate. Biomedicine Hub 2024, 1-16. DOI: 10.1159/000543138.
- Renal Angptl4 is a key fibrogenic molecule in progressive diabetic kidney diseaseSwayam Prakash Srivastava et al. ,Renal Angptl4 is a key fibrogenic molecule in progressive diabetic kidney disease.Sci. Adv.10,eadn6068(2024).DOI:10.1126/sciadv.adn6068
- Renal Angptl4 is a key fibrogenic molecule in progressive diabetic kidney diseaseSrivastava S, Zhou H, Shenoi R, Morris M, Lainez-Mas B, Goedeke L, Rajendran B, Setia O, Aryal B, Kanasaki K, Koya D, Inoki K, Dardik A, Bell T, Fernández-Hernando C, Shulman G, Goodwin J. Renal Angptl4 is a key fibrogenic molecule in progressive diabetic kidney disease. Science Advances 2024, 10: eadn6068. PMID: 39630889, PMCID: PMC11616692, DOI: 10.1126/sciadv.adn6068.
- Ezrin drives adaptation of monocytes to the inflamed lung microenvironmentGudneppanavar R, Di Pietro C, H Öz H, Zhang P, Cheng E, Huang P, Tebaldi T, Biancon G, Halene S, Hoppe A, Kim C, Gonzalez A, Krause D, Egan M, Gupta N, Murray T, Bruscia E. Ezrin drives adaptation of monocytes to the inflamed lung microenvironment. Cell Death & Disease 2024, 15: 864. PMID: 39613751, PMCID: PMC11607083, DOI: 10.1038/s41419-024-07255-8.
- Suppression of neurons in circumventricular organs enables months-long survival without water in thirteen-lined ground squirrelsJunkins M, Feng N, Merriman D, Bagriantsev S, Gracheva E. Suppression of neurons in circumventricular organs enables months-long survival without water in thirteen-lined ground squirrels. Science 2024, 386: 1048-1055. PMID: 39607925, DOI: 10.1126/science.adp8358.
- GABAA receptor π forms channels that stimulate ERK through a G-protein-dependent pathwayWang Y, Zhang Y, Li W, Salovska B, Zhang J, Li T, Li H, Liu Y, Kaczmarek L, Pusztai L, Klein D. GABAA receptor π forms channels that stimulate ERK through a G-protein-dependent pathway. Molecular Cell 2024 PMID: 39642883, DOI: 10.1016/j.molcel.2024.11.016.
- Compartmentalized pooling generates orientation selectivity in wide-field amacrine cellsLei W, Clark D, Demb J. Compartmentalized pooling generates orientation selectivity in wide-field amacrine cells. Proceedings Of The National Academy Of Sciences Of The United States Of America 2024, 121: e2411130121. PMID: 39602271, PMCID: PMC11626119, DOI: 10.1073/pnas.2411130121.
- Regulation of cardiac function by the autonomic nervous systemHafez O, Chang R. Regulation of cardiac function by the autonomic nervous system. Physiology 2024 PMID: 39585760, DOI: 10.1152/physiol.00018.2024.
- Monoclonal antibodies that block Roundabout 1 and 2 signaling target pathological ocular neovascularization through myeloid cellsGeraldo L, Xu Y, Mouthon G, Furtado J, Leser F, Blazer L, Adams J, Zhang S, Zheng L, Song E, Robinson M, Thomas J, Sidhu S, Eichmann A. Monoclonal antibodies that block Roundabout 1 and 2 signaling target pathological ocular neovascularization through myeloid cells. Science Translational Medicine 2024, 16: eadn8388. PMID: 39565875, DOI: 10.1126/scitranslmed.adn8388.
- Bioengineering on the Front LinesTonnessen B, Dardik A. Bioengineering on the Front Lines. JAMA Surgery 2024, 160 PMID: 39565609, DOI: 10.1001/jamasurg.2024.5137.
- Spatiotemporal control of subcellular O-GlcNAc signaling using Opto-OGTOng Q, Lim L, Goh C, Liao Y, Chan S, Lim C, Kam V, Yap J, Tseng T, Desrouleaux R, Wang L, Ler S, Lim S, Kim S, Sobota R, Bennett A, Han W, Yang X. Spatiotemporal control of subcellular O-GlcNAc signaling using Opto-OGT. Nature Chemical Biology 2024, 1-9. PMID: 39543398, DOI: 10.1038/s41589-024-01770-7.
- Patient-specific, multiscale modelling of neointimal hyperplasia in lower-limb vein grafts using readily available clinical dataNinno F, Chiastra C, Donadoni F, Dardik A, Strosberg D, Aboian E, Tsui J, Balabani S, Díaz-Zuccarini V. Patient-specific, multiscale modelling of neointimal hyperplasia in lower-limb vein grafts using readily available clinical data. Journal Of Biomechanics 2024, 177: 112428. PMID: 39561605, DOI: 10.1016/j.jbiomech.2024.112428.
- Abstract 4144255: Treatment of Human Engineered Heart Tissue with Serum from Cancer Patients with Clonal Hematopoiesis of Indeterminate Potential Cytokine Leads to Impaired FunctionKaur H, Halder S, Espinoza J, Chen N, VanOudenhove J, Biancon G, Gu S, Chakraborty R, Jain K, Park J, Qyang Y, Ibrahim E, Halene S, Hwa J, Campbell S, Jha A, Kwan J. Abstract 4144255: Treatment of Human Engineered Heart Tissue with Serum from Cancer Patients with Clonal Hematopoiesis of Indeterminate Potential Cytokine Leads to Impaired Function. Circulation 2024, 150: a4144255-a4144255. DOI: 10.1161/circ.150.suppl_1.4144255.
- Adamts1 and Cyst Expansion in Polycystic Kidney Disease.Kakade V, Akman Z, Motrapu M, Cassini M, Xu L, Moeckel G, Somlo S, Cantley L. Adamts1 and Cyst Expansion in Polycystic Kidney Disease. Journal Of The American Society Of Nephrology 2024 PMID: 39514301, DOI: 10.1681/asn.0000000557.
- Molecular Profiling of Mouse Models of Loss or Gain of Function of the KCNT1 (Slack) Potassium Channel and Antisense Oligonucleotide TreatmentSun F, Wang H, Wu J, Quraishi I, Zhang Y, Pedram M, Gao B, Jonas E, Nguyen V, Wu S, Mabrouk O, Jafar-nejad P, Kaczmarek L. Molecular Profiling of Mouse Models of Loss or Gain of Function of the KCNT1 (Slack) Potassium Channel and Antisense Oligonucleotide Treatment. Biomolecules 2024, 14: 1397. PMID: 39595574, PMCID: PMC11591899, DOI: 10.3390/biom14111397.
- Single-cell transcriptomic and proteomic analysis of Parkinson’s disease brainsZhu B, Park J, Coffey S, Russo A, Hsu I, Wang J, Su C, Chang R, Lam T, Gopal P, Ginsberg S, Zhao H, Hafler D, Chandra S, Zhang L. Single-cell transcriptomic and proteomic analysis of Parkinson’s disease brains. Science Translational Medicine 2024, 16: eabo1997. PMID: 39475571, DOI: 10.1126/scitranslmed.abo1997.
- DeepVID v2: self-supervised denoising with decoupled spatiotemporal enhancement for low-photon voltage imagingLiu C, Lu J, Wu Y, Ye X, Ahrens A, Platisa J, Pieribone V, Chen J, Tian L. DeepVID v2: self-supervised denoising with decoupled spatiotemporal enhancement for low-photon voltage imaging. Neurophotonics 2024, 11: 045007-045007. PMID: 39474199, PMCID: PMC11519979, DOI: 10.1117/1.nph.11.4.045007.
- Structure, interaction and nervous connectivity of beta cell primary ciliaMüller A, Klena N, Pang S, Garcia L, Topcheva O, Aurrecoechea Duran S, Sulaymankhil D, Seliskar M, Mziaut H, Schöniger E, Friedland D, Kipke N, Kretschmar S, Münster C, Weitz J, Distler M, Kurth T, Schmidt D, Hess H, Xu C, Pigino G, Solimena M. Structure, interaction and nervous connectivity of beta cell primary cilia. Nature Communications 2024, 15: 9168. PMID: 39448638, PMCID: PMC11502866, DOI: 10.1038/s41467-024-53348-5.
- Preclinical Evidence of the Effects of Sweet Flavors: Sweetness Increases Nicotine Intake and SeekingBagdas D, Addy N. Preclinical Evidence of the Effects of Sweet Flavors: Sweetness Increases Nicotine Intake and Seeking. Nicotine & Tobacco Research 2024, ntae241. PMID: 39413033, DOI: 10.1093/ntr/ntae241.
- Carotid artery stenting versus carotid endarterectomy for symptomatic or asymptomatic extracranial carotid stenosis: A national cohort studyKrittanawong C, Ang S, Tangsrivimol J, Qadeer Y, Wang Z, Virk H, Khalid U, Sharma S, Dardik A. Carotid artery stenting versus carotid endarterectomy for symptomatic or asymptomatic extracranial carotid stenosis: A national cohort study. Journal Of Stroke And Cerebrovascular Diseases 2024, 33: 108094. PMID: 39424210, DOI: 10.1016/j.jstrokecerebrovasdis.2024.108094.
- High-fat-diet-induced hepatic insulin resistance per se attenuates murine de novo lipogenesisGoedeke L, Strober J, Suh R, Paolella L, Li X, Rogers J, Petersen M, Nasiri A, Casals G, Kahn M, Cline G, Samuel V, Shulman G, Vatner D. High-fat-diet-induced hepatic insulin resistance per se attenuates murine de novo lipogenesis. IScience 2024, 27: 111175. PMID: 39524330, PMCID: PMC11550620, DOI: 10.1016/j.isci.2024.111175.
- An International, Expert-Based Delphi Consensus Document on Controversial Issues about TransCarotid Artery Revascularization (TCAR)Paraskevas K, AbuRahma A, Abularrage C, Clair D, Eldrup-Jorgensen J, Kashyap V, Dardik A, de Borst G, Dermody M, Faggioli G, Hicks C, Kwolek C, Lyden S, Mansilha A, Van Herzeele I, Myrcha P, Leal Lorenzo J, Jim J, Pini R, Secemsky E, Spinelli F, Capoccia L, Stone D, Stoner M, Zeebregts C, Lal B, Schneider P, Malas M, Schermerhorn M. An International, Expert-Based Delphi Consensus Document on Controversial Issues about TransCarotid Artery Revascularization (TCAR). Annals Of Vascular Surgery 2024, 110: 42-53. PMID: 39413993, DOI: 10.1016/j.avsg.2024.09.048.
- CCR2+ monocytes are dispensable to resolve acute pulmonary Pseudomonas aeruginosa infections in WT and cystic fibrosis miceÖz H, Braga C, Gudneppanavar R, Di Pietro C, Huang P, Zhang P, Krause D, Egan M, Murray T, Bruscia E. CCR2+ monocytes are dispensable to resolve acute pulmonary Pseudomonas aeruginosa infections in WT and cystic fibrosis mice. Journal Of Leukocyte Biology 2024, qiae218. PMID: 39365279, DOI: 10.1093/jleuko/qiae218.
- Plateau depolarizations in spontaneously active neurons detected by calcium or voltage imagingMilicevic K, Ivanova V, Lovic D, Platisa J, Andjus P, Antic S. Plateau depolarizations in spontaneously active neurons detected by calcium or voltage imaging. Scientific Reports 2024, 14: 22787. PMID: 39367010, PMCID: PMC11452489, DOI: 10.1038/s41598-024-70319-4.
- Using Imaging Mass Cytometry to Define Cell Identities in AKI and CKD in HumansBudiman T, Shelar A, Baker M, Weiss M, Cantley L, Kakade V. Using Imaging Mass Cytometry to Define Cell Identities in AKI and CKD in Humans. Journal Of The American Society Of Nephrology 2024, 35: 10.1681/asn.2024g4m5sdnf. DOI: 10.1681/asn.2024g4m5sdnf.
- Segment-Specific Cyst Index (SSCI): A Quantitative Analysis of Segment-Specific Responses during CystogenesisAkman Z, Kakade V, Cantley L. Segment-Specific Cyst Index (SSCI): A Quantitative Analysis of Segment-Specific Responses during Cystogenesis. Journal Of The American Society Of Nephrology 2024, 35: 10.1681/asn.2024mpmapkd5. DOI: 10.1681/asn.2024mpmapkd5.
- Tubule-Specific Deletion of Adamts1 Slows Cyst Expansion in Polycystic Kidney DiseaseKakade V, Akman Z, Motrapu M, Cantley L. Tubule-Specific Deletion of Adamts1 Slows Cyst Expansion in Polycystic Kidney Disease. Journal Of The American Society Of Nephrology 2024, 35: 10.1681/asn.20246ecyxtfs. DOI: 10.1681/asn.20246ecyxtfs.
- Analysis of Kidney Biopsies from Patients with Glomerulonephritis Using Imaging Mass Cytometry Reveals Increase in Immune Cells with Associated Dedifferentiation and Injury of Tubular CellsWeiss M, Kakade V, Baker M, Budiman T, Shelar A, Cantley L. Analysis of Kidney Biopsies from Patients with Glomerulonephritis Using Imaging Mass Cytometry Reveals Increase in Immune Cells with Associated Dedifferentiation and Injury of Tubular Cells. Journal Of The American Society Of Nephrology 2024, 35: 10.1681/asn.202490mzwbkc. DOI: 10.1681/asn.202490mzwbkc.
- Understanding Pathophysiology of Acute Interstitial Nephritis through Spatial Characterization of Cell-Cell Interactions Using Imaging Mass Cytometry in a Human Biopsy CohortBaker M, Kakade V, Budiman T, Weiss M, Shelar A, Moledina D, Cantley L. Understanding Pathophysiology of Acute Interstitial Nephritis through Spatial Characterization of Cell-Cell Interactions Using Imaging Mass Cytometry in a Human Biopsy Cohort. Journal Of The American Society Of Nephrology 2024, 35: 10.1681/asn.2024n6j4nxq1. DOI: 10.1681/asn.2024n6j4nxq1.
- Myofibroblast-Macrophage Cross-Talk Supports Proliferative Tubule Repair after Kidney InjuryBharathan B, Xu L, Guo J, Cantley L. Myofibroblast-Macrophage Cross-Talk Supports Proliferative Tubule Repair after Kidney Injury. Journal Of The American Society Of Nephrology 2024, 35: 10.1681/asn.20249phzkecs. DOI: 10.1681/asn.20249phzkecs.
- Urine Proteomic Signatures of Kidney Function Decline after HospitalizationWen Y, Menez S, Philbrook H, Moledina D, Bhatraju P, Coca S, Chinchilli V, Go A, Siew E, Kimmel P, Ikizler T, Hsu C, Himmelfarb J, Cantley L, Parikh C. Urine Proteomic Signatures of Kidney Function Decline after Hospitalization. Journal Of The American Society Of Nephrology 2024, 35: 10.1681/asn.20245v3jz4vr. DOI: 10.1681/asn.20245v3jz4vr.
- AKI in the Kidney Precision Medicine Project: Acute Tubular Injury vs. Acute Interstitial NephritisSchaub J, Castro A, Menez S, Wen Y, Menon R, Bhatraju P, Wilson F, Coca S, Eadon M, Bomback A, Moledina D, Cantley L, Palevsky P, D'Agati V, Randhawa P, Murugan R, Alpers C, Kretzler M, Himmelfarb J, Parikh C. AKI in the Kidney Precision Medicine Project: Acute Tubular Injury vs. Acute Interstitial Nephritis. Journal Of The American Society Of Nephrology 2024, 35: 10.1681/asn.2024cxh8wvky. DOI: 10.1681/asn.2024cxh8wvky.
- Small molecules targeting selective PCK1 and PGC-1α lysine acetylation cause anti-diabetic action through increased lactate oxidationMutlu B, Sharabi K, Sohn J, Yuan B, Latorre-Muro P, Qin X, Yook J, Lin H, Yu D, Camporez J, Kajimura S, Shulman G, Hui S, Kamenecka T, Griffin P, Puigserver P. Small molecules targeting selective PCK1 and PGC-1α lysine acetylation cause anti-diabetic action through increased lactate oxidation. Cell Chemical Biology 2024, 31: 1772-1786.e5. PMID: 39341205, PMCID: PMC11500315, DOI: 10.1016/j.chembiol.2024.09.001.
- Association between Preoperative Neutrophil-lymphocyte Ratio and All-cause Mortality in Patients Treated with Thoracic Endovascular Aortic Repair for Degenerative Thoracic Aortic AneurysmKano M, Nishibe T, Dardik A, Iwahashi T, Nakano Y, Shimahara Y. Association between Preoperative Neutrophil-lymphocyte Ratio and All-cause Mortality in Patients Treated with Thoracic Endovascular Aortic Repair for Degenerative Thoracic Aortic Aneurysm. Annals Of Vascular Surgery 2024, 110: 255-264. PMID: 39341560, DOI: 10.1016/j.avsg.2024.07.110.
- Specific retinal neurons regulate context-dependent defensive responses to visual threatLee T, Weinberg-Wolf H, Zapadka T, Rudenko A, Demb J, Kim I. Specific retinal neurons regulate context-dependent defensive responses to visual threat. PNAS Nexus 2024, 3: pgae423. PMID: 39359403, PMCID: PMC11443969, DOI: 10.1093/pnasnexus/pgae423.
- IL-1β Induces Human Endothelial Surface Expression of IL-15 by Relieving let-7c-3p Suppression of Protein Translation.Mullan C, Summer L, Lopez-Giraldez F, Tobiasova Z, Manes T, Yasothan S, Song G, Jane-Wit D, Saltzman W, Pober J. IL-1β Induces Human Endothelial Surface Expression of IL-15 by Relieving let-7c-3p Suppression of Protein Translation. The Journal Of Immunology 2024, 213: 1338-1348. PMID: 39302113, PMCID: PMC11493510, DOI: 10.4049/jimmunol.2400331.
- Ceramide synthesis inhibitors prevent lipid-induced insulin resistance through the DAG-PKCε-insulin receptorT1150 phosphorylation pathwayXu W, Zhang D, Ma Y, Gaspar R, Kahn M, Nasiri A, Murray S, Samuel V, Shulman G. Ceramide synthesis inhibitors prevent lipid-induced insulin resistance through the DAG-PKCε-insulin receptorT1150 phosphorylation pathway. Cell Reports 2024, 43: 114746. PMID: 39302831, DOI: 10.1016/j.celrep.2024.114746.
- Endothelial TGF-β Signaling Regulates Endothelial-Mesenchymal Transition During Arteriovenous Fistula Remodeling in Mice With Chronic Kidney DiseaseZhang W, Gonzalez L, Li X, Bai H, Li Z, Taniguchi R, Langford J, Ohashi Y, Thaxton C, Aoyagi Y, Yatsula B, Martin K, Goodwin J, Tellides G, Long X, Shu C, Dardik A. Endothelial TGF-β Signaling Regulates Endothelial-Mesenchymal Transition During Arteriovenous Fistula Remodeling in Mice With Chronic Kidney Disease. Arteriosclerosis Thrombosis And Vascular Biology 2024, 44: 2509-2526. PMID: 39297205, PMCID: PMC11593991, DOI: 10.1161/atvbaha.124.320933.
- Scaleable production of highly loaded protein nanoparticles for immune modulationCaplan M, Baldwin R, Yin X, Grishin A, Eisenbarth S, Sampson H, Bottomly K, Prud’homme R. Scaleable production of highly loaded protein nanoparticles for immune modulation. Communications Materials 2024, 5: 191. DOI: 10.1038/s43246-024-00626-w.
- Abstract PR-05: Endocrine beta-cell stress promotes pancreatic ductal adenocarcinoma through endocrine-exocrine cell crosstalkGarcia C, Venkat A, McQuaid D, Agabiti S, Tong A, Cardone R, Kibbey R, Krishnaswamy S, Muzumdar M. Abstract PR-05: Endocrine beta-cell stress promotes pancreatic ductal adenocarcinoma through endocrine-exocrine cell crosstalk. Cancer Research 2024, 84: pr-05-pr-05. DOI: 10.1158/1538-7445.pancreatic24-pr-05.
- Abstract PR-06: Dietary fats dictate pancreatic cancer fate via phospholipid saturationRuiz C, Ge X, McDonnell R, McQuaid D, Kaplan J, Li G, Rudolph M, Gorelick F, Wysolmerski J, Canals D, Haley J, Rodeheffer M, Muzumdar M. Abstract PR-06: Dietary fats dictate pancreatic cancer fate via phospholipid saturation. Cancer Research 2024, 84: pr-06-pr-06. DOI: 10.1158/1538-7445.pancreatic24-pr-06.
- Abstract PR-01: Systemic targeting of therapeutic RNA to pancreatic ductal adenocarcinoma via a novel, cell-penetrating, and nucleic acid-binding monoclonal antibodyMartinez-Saucedo D, Quijano E, Ianniello Z, Rackear M, Liu Y, Hegan D, Chen H, Shan X, Tseng R, Yugawa D, Pinto-Medici N, Chowdhury S, Bindra R, Robert M, Saltzman W, Escobar-Hoyos L, Glazer P. Abstract PR-01: Systemic targeting of therapeutic RNA to pancreatic ductal adenocarcinoma via a novel, cell-penetrating, and nucleic acid-binding monoclonal antibody. Cancer Research 2024, 84: pr-01-pr-01. DOI: 10.1158/1538-7445.pancreatic24-pr-01.
- Effect of Weight Loss on Skeletal Muscle Bioactive Lipids in People With Obesity and Type 2 Diabetes.Petersen M, Yoshino M, Smith G, Gaspar R, Kahn M, Samovski D, Shulman G, Klein S. Effect of Weight Loss on Skeletal Muscle Bioactive Lipids in People With Obesity and Type 2 Diabetes. Diabetes 2024, 73: 2055-2064. PMID: 39264820, PMCID: PMC11579410, DOI: 10.2337/db24-0083.
- Density and distribution patterns of seafloor macrolitter in the eastern Red SeaMartynova A, Rodrigue M, Pieribone V, Qurban M, Duarte C. Density and distribution patterns of seafloor macrolitter in the eastern Red Sea. The Science Of The Total Environment 2024, 953: 176042. PMID: 39244039, DOI: 10.1016/j.scitotenv.2024.176042.
- Does Eosinophil Heterogeneity Translate into Functional Diversity? A Review of the Evolving Paradigm of Eosinophil Heterogeneity in Asthma.Wilson GE, Gautam S, Chupp GL. Does Eosinophil Heterogeneity Translate into Functional Diversity? A Review of the Evolving Paradigm of Eosinophil Heterogeneity in Asthma. Biomedicines 2024, 12 PMID: 39335525, DOI: 10.3390/biomedicines12092011.
- 285 Development of an electrochemiluminescence CFTR immunoassayBrowne J, Lee J, Peterec K, Garrison A, Bruscia E, Saltzman W, Egan M. 285 Development of an electrochemiluminescence CFTR immunoassay. Journal Of Cystic Fibrosis 2024, 23: s152. DOI: 10.1016/s1569-1993(24)01125-1.
- 395 Altered hematopoiesis and functional decline of hematopoietic stem cells in cystic fibrosis miceBraga C, Mancuso R, Thompson E, Oez H, Gudneppannavar R, Zhang P, Huang P, Egan M, Murray T, Krause D, Bruscia E. 395 Altered hematopoiesis and functional decline of hematopoietic stem cells in cystic fibrosis mice. Journal Of Cystic Fibrosis 2024, 23: s207-s208. DOI: 10.1016/s1569-1993(24)01235-9.
- 264 Poly(amine-co-ester) nanoparticle delivery of CFTR mRNA shows restoration of CFTR activity in cystic fibrosis airway modelsGarrison A, Lee J, Browne J, Akhtar L, Peterec K, Suberi A, Eaton D, Ene M, Zhang X, Whang C, Oez H, Kizilirmak T, Bruscia E, Piotrowski-Daspit A, Saltzman W, Egan M. 264 Poly(amine-co-ester) nanoparticle delivery of CFTR mRNA shows restoration of CFTR activity in cystic fibrosis airway models. Journal Of Cystic Fibrosis 2024, 23: s140-s141. DOI: 10.1016/s1569-1993(24)01104-4.
- 256 Primary mouse tracheal basal cells transplanted into CFTR−/− mice reconstitute CFTR functionChen K, Berical A, Oez H, Braga C, Garrison A, Gudneppanavar R, Egan M, Kotton D, Bruscia E, Hawkins F. 256 Primary mouse tracheal basal cells transplanted into CFTR−/− mice reconstitute CFTR function. Journal Of Cystic Fibrosis 2024, 23: s136. DOI: 10.1016/s1569-1993(24)01096-8.
- 219 CFTR dysfunction shapes airway immune cell compositions contributing to lung pathogenesis in children with cystic fibrosisKizilirmak T, Yin H, Garrison A, Browne J, Bruscia E, Egan M, Britto C. 219 CFTR dysfunction shapes airway immune cell compositions contributing to lung pathogenesis in children with cystic fibrosis. Journal Of Cystic Fibrosis 2024, 23: s119. DOI: 10.1016/s1569-1993(24)01059-2.
- 313 BEST4+ CFTR high expresser cells in normal rat are neuropods that sense and respond to luminal pH and are altered in dF508 CF intestineJin J, dos Reis D, Muiler C, Zagoren E, Donnelley M, Parsons D, Sumigray K, Ameen N. 313 BEST4+ CFTR high expresser cells in normal rat are neuropods that sense and respond to luminal pH and are altered in dF508 CF intestine. Journal Of Cystic Fibrosis 2024, 23: s167. DOI: 10.1016/s1569-1993(24)01153-6.
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