Primary Faculty Publications

2020

Neurobehavioral performance of PAH exposure in male coal miners in Shanxi, China: a cross-sectional study.Wang F, Yang L, Zhang B, Liu G, Wang C, Zhang Y, Wang T. Int Arch Occup Environ Health. 2020 Feb 14; 2020 Feb 14. PMID: 32060638.
The mechanism of β-N-methylamino-l-alanine inhibition of tRNA aminoacylation and its impact on misincorporation.Han NC, Bullwinkle TJ, Loeb KF, Faull KF, Mohler K, Rinehart J, Ibba M. J Biol Chem. 2020 Jan 31; 2019 Dec 20. PMID: 31862734.
ABC transporters control ATP release through cholesterol-dependent volume-regulated anion channel activity.Dunn PJ, Salm EJ, Tomita S. J Biol Chem. 2020 Jan 27; 2020 Jan 27. PMID: 31988241.
Hepatic TET3 contributes to type-2 diabetes by inducing the HNF4α fetal isoform.Da Li, Cao T, Sun X, Jin S, Di Xie, Huang X, Yang X, Carmichael GG, Taylor HS, Diano S, Huang Y. Nat Commun. 2020 Jan 17; 2020 Jan 17. PMID: 31953394.
Mechanisms involved in AMPK-mediated deposition of tight junction components to the plasma membrane.Wu J, Rowart P, Jouret F, Gassaway BM, Rajendran V, Rinehart J, Caplan MJ. Am J Physiol Cell Physiol. 2020 Jan 8; 2020 Jan 8. PMID: 31913699.
Archaeal Ribosomal Proteins Possess Nuclear Localization Signal-Type Motifs: Implications for the Origin of the Cell Nucleus.Melnikov S, Kwok HS, Manakongtreecheep K, van den Elzen A, Thoreen CC, Söll D. Mol Biol Evol. 2020 Jan 1. PMID: 31501901.

2019

A mitochondrial megachannel resides in monomeric F₁F_O ATP synthase.Mnatsakanyan N, Llaguno MC, Yang Y, Yan Y, Weber J, Sigworth FJ, Jonas EA. Nat Commun. 2019 Dec 20; 2019 Dec 20. PMID: 31862883.
Alanyl-tRNA Synthetase Quality Control Prevents Global Dysregulation of the Escherichia coli Proteome.Kelly P, Backes N, Mohler K, Buser C, Kavoor A, Rinehart J, Phillips G, Ibba M. mBio. 2019 Dec 17; 2019 Dec 17. PMID: 31848288.
Computation-guided analysis of paroxetine binding to hSERT reveals functionally important structural elements and dynamics.Abramyan AM, Slack RD, Meena S, Davis BA, Newman AH, Singh SK, Shi L. Neuropharmacology. 2019 Dec 15; 2018 Nov 1. PMID: 30391505.
Distinct Hepatic PKA and CDK Signaling Pathways Control Activity-Independent Pyruvate Kinase Phosphorylation and Hepatic Glucose Production.Gassaway BM, Cardone RL, Padyana AK, Petersen MC, Judd ET, Hayes S, Tong S, Barber KW, Apostolidi M, Abulizi A, Sheetz JB, Kshitiz, Aerni HR, Gross S, Kung C, Samuel VT, Shulman GI, Kibbey RG, Rinehart J. Cell Rep. 2019 Dec 10. PMID: 31825824.
Considering the Links Between Nonalcoholic Fatty Liver Disease and Insulin Resistance: Revisiting the Role of Protein Kinase C ε.Samuel VT, Petersen MC, Gassaway BM, Vatner DF, Rinehart J, Shulman GI. Hepatology. 2019 Dec; 2019 Aug 23. PMID: 31220350.
Microglial UCP2 Mediates Inflammation and Obesity Induced by High-Fat Feeding.Kim JD, Yoon NA, Jin S, Diano S. Cell Metab. 2019 Nov 5; 2019 Sep 5. PMID: 31495690.
Holding open the door reveals a new view of polycystin channel function.Caplan MJ. EMBO Rep. 2019 Nov 5; 2019 Sep 26. PMID: 31556469.
Anatomy and function of the vertebral column lymphatic network in mice.Jacob L, Boisserand LSB, Geraldo LHM, de Brito Neto J, Mathivet T, Antila S, Barka B, Xu Y, Thomas JM, Pestel J, Aigrot MS, Song E, Nurmi H, Lee S, Alitalo K, Renier N, Eichmann A, Thomas JL. Nat Commun. 2019 Oct 9; 2019 Oct 9. PMID: 31597914.
Sex difference in kidney electrolyte transport II: impact of K⁺ intake on thiazide-sensitive cation excretion in male and female mice.Li J, Xu S, Yang L, Yang J, Wang CJ, Weinstein AM, Palmer LG, Wang T. Am J Physiol Renal Physiol. 2019 Oct 1; 2019 Aug 7. PMID: 31390232.
Osmolyte Depletion and Thirst Suppression Allow Hibernators to Survive for Months without Water.Feng NY, Junkins MS, Merriman DK, Bagriantsev SN, Gracheva EO. Curr Biol. 2019 Sep 23; 2019 Sep 5. PMID: 31495581.
A Novel Bromine-Containing Paroxetine Analogue Provides Mechanistic Clues for Binding Ambiguity at the Central Primary Binding Site of the Serotonin Transporter.Slack RD, Abramyan AM, Tang H, Meena S, Davis BA, Bonifazi A, Giancola JB, Deschamps JR, Naing S, Yano H, Singh SK, Newman AH, Shi L. ACS Chem Neurosci. 2019 Sep 18; 2019 Aug 22. PMID: 31424193.
Spatiotemporal dynamics of odor responses in the lateral and dorsal olfactory bulb.Baker KL, Vasan G, Gumaste A, Pieribone VA, Verhagen JV. PLoS Biol. 2019 Sep; 2019 Sep 18. PMID: 31532763.
Zebrafish behavioural profiling identifies GABA and serotonin receptor ligands related to sedation and paradoxical excitation.McCarroll MN, Gendelev L, Kinser R, Taylor J, Bruni G, Myers-Turnbull D, Helsell C, Carbajal A, Rinaldi C, Kang HJ, Gong JH, Sello JK, Tomita S, Peterson RT, Keiser MJ, Kokel D. Nat Commun. 2019 Sep 9; 2019 Sep 9. PMID: 31501447.
Cardiomyocyte d-dopachrome tautomerase protects against heart failure.Ma Y, Su KN, Pfau D, Rao VS, Wu X, Hu X, Leng L, Du X, Piecychna M, Bedi K, Campbell SG, Eichmann A, Testani JM, Margulies KB, Bucala R, Young LH. JCI Insight. 2019 Sep 5; 2019 Sep 5. PMID: 31484822.
Piezo2 integrates mechanical and thermal cues in vertebrate mechanoreceptors.Zheng W, Nikolaev YA, Gracheva EO, Bagriantsev SN. Proc Natl Acad Sci U S A. 2019 Aug 27; 2019 Aug 14. PMID: 31413193.
Neural mechanisms of thermoregulation.Gracheva EO, Bagriantsev SN. Neurosci Lett. 2019 Aug 10; 2019 Jun 3. PMID: 31170427.
Molecular constituents and localization of the ionotropic GABA receptor complex in vivo.Tomita S. Curr Opin Neurobiol. 2019 Aug; 2019 Feb 19. PMID: 30784980.
Tracking Newly Released Synaptic Vesicle Proteins at Ribbon Active Zones.Vaithianathan T, Wollmuth LP, Henry D, Zenisek D, Matthews G. iScience. 2019 Jul 26; 2019 Jun 13. PMID: 31247447.
Noninvasive In Vivo Quantification of Adeno-Associated Virus Serotype 9-Mediated Expression of the Sodium/Iodide Symporter Under Hindlimb Ischemia and Neuraminidase Desialylation in Skeletal Muscle Using Single-Photon Emission Computed Tomography/Computed Tomography.Boutagy NE, Ravera S, Papademetris X, Onofrey JA, Zhuang ZW, Wu J, Feher A, Stacy MR, French BA, Annex BH, Carrasco N, Sinusas AJ. Circ Cardiovasc Imaging. 2019 Jul; 2019 Jul 12. PMID: 31296047.
Dual Sensing of Physiologic pH and Calcium by EFCAB9 Regulates Sperm Motility.Hwang JY, Mannowetz N, Zhang Y, Everley RA, Gygi SP, Bewersdorf J, Lishko PV, Chung JJ. Cell. 2019 May 30; 2019 May 2. PMID: 31056283.
Endophilin-A2 dependent VEGFR2 endocytosis promotes sprouting angiogenesis.Genet G, Boyé K, Mathivet T, Ola R, Zhang F, Dubrac A, Li J, Genet N, Henrique Geraldo L, Benedetti L, Künzel S, Pibouin-Fragner L, Thomas JL, Eichmann A. Nat Commun. 2019 May 28; 2019 May 28. PMID: 31138815.
Leukocyte Cytoskeleton Polarization Is Initiated by Plasma Membrane Curvature from Cell Attachment.Ren C, Yuan Q, Braun M, Zhang X, Petri B, Zhang J, Kim D, Guez-Haddad J, Xue W, Pan W, Fan R, Kubes P, Sun Z, Opatowsky Y, Polleux F, Karatekin E, Tang W, Wu D. Dev Cell. 2019 Apr 22; 2019 Mar 28. PMID: 30930167.
Everything You Always Wanted to Know about β₃-AR * (* But Were Afraid to Ask).Schena G, Caplan MJ. Cells. 2019 Apr 16; 2019 Apr 16. PMID: 30995798.
Comprehensive profiling of the STE20 kinase family defines features essential for selective substrate targeting and signaling output.Miller CJ, Lou HJ, Simpson C, van de Kooij B, Ha BH, Fisher OS, Pirman NL, Boggon TJ, Rinehart J, Yaffe MB, Linding R, Turk BE. PLoS Biol. 2019 Mar; 2019 Mar 21. PMID: 30897078.
Convergent Identification and Interrogation of Tumor-Intrinsic Factors that Modulate Cancer Immunity In Vivo.Codina A, Renauer PA, Wang G, Chow RD, Park JJ, Ye H, Zhang K, Dong MB, Gassaway B, Ye L, Errami Y, Shen L, Chang A, Jain D, Herbst RS, Bosenberg M, Rinehart J, Fan R, Chen S. Cell Syst. 2019 Feb 27; 2019 Feb 20. PMID: 30797773.
A Cross-Species Analysis Reveals a General Role for Piezo2 in Mechanosensory Specialization of Trigeminal Ganglia from Tactile Specialist Birds.Schneider ER, Anderson EO, Feketa VV, Mastrotto M, Nikolaev YA, Gracheva EO, Bagriantsev SN. Cell Rep. 2019 Feb 19. PMID: 30784581.
Mentors: Ron Kaback.Carrasco N. J Gen Physiol. 2019 Feb 4; 2019 Jan 23. PMID: 30674562.
A hydrophobic gate in the inner pore helix is the major determinant of inactivation in mechanosensitive Piezo channels.Zheng W, Gracheva EO, Bagriantsev SN. Elife. 2019 Jan 10; 2019 Jan 10. PMID: 30628892.
A Carboxy-Terminal Monoleucine-Based Motif Participates in the Basolateral Targeting of the Na+/I- Symporter.Martín M, Modenutti CP, Peyret V, Geysels RC, Darrouzet E, Pourcher T, Masini-Repiso AM, Martí MA, Carrasco N, Nicola JP. Endocrinology. 2019 Jan 1. PMID: 30496374.
Polycystin-1 regulates bone development through an interaction with the transcriptional coactivator TAZ.Merrick D, Mistry K, Wu J, Gresko N, Baggs JE, Hogenesch JB, Sun Z, Caplan MJ. Hum Mol Genet. 2019 Jan 1. PMID: 30215740.

2018

The Polycystin Complex Reveals Its Complexity.Padovano V, Caplan MJ. Biochemistry. 2018 Dec 26; 2018 Dec 12. PMID: 30540438.
To BBB or Not to BBB?Thomas JL, Eichmann A. Dev Cell. 2018 Dec 17. PMID: 30562511.
Loss of protein synthesis quality control in host-restricted organisms.Melnikov SV, van den Elzen A, Stevens DL, Thoreen CC, Söll D. Proc Natl Acad Sci U S A. 2018 Dec 4; 2018 Nov 19. PMID: 30455292.
Overexpression of melanocortin 2 receptor accessory protein 2 (MRAP2) in adult paraventricular MC4R neurons regulates energy intake and expenditure.Bruschetta G, Kim JD, Diano S, Chan LF. Mol Metab. 2018 Dec; 2018 Oct 4. PMID: 30352741.
Fast, in vivo voltage imaging using a red fluorescent indicator.Kannan M, Vasan G, Huang C, Haziza S, Li JZ, Inan H, Schnitzer MJ, Pieribone VA. Nat Methods. 2018 Dec; 2018 Nov 12. PMID: 30420685.
Newly synthesized polycystin-1 takes different trafficking pathways to the apical and ciliary membranes.Gilder AL, Chapin HC, Padovano V, Hueschen CL, Rajendran V, Caplan MJ. Traffic. 2018 Dec; 2018 Sep 24. PMID: 30125442.
SMAD4 Prevents Flow Induced Arteriovenous Malformations by Inhibiting Casein Kinase 2.Ola R, Künzel SH, Zhang F, Genet G, Chakraborty R, Pibouin-Fragner L, Martin K, Sessa W, Dubrac A, Eichmann A. Circulation. 2018 Nov 20. PMID: 29976569.
Potassium conservation is impaired in mice with reduced renal expression of Kir4.1.Malik S, Lambert E, Zhang J, Wang T, Clark HL, Cypress M, Goldman BI, Porter GA Jr, Pena S, Nino W, Gray DA. Am J Physiol Renal Physiol. 2018 Nov 1; 2018 Aug 15. PMID: 30110571.
FEBS Letters Special Issue on Exocytosis and Endocytosis.Karatekin E, Rothman JE. FEBS Lett. 2018 Nov. PMID: 30417372.
Toward a unified picture of the exocytotic fusion pore.Karatekin E. FEBS Lett. 2018 Nov; 2018 Oct 26. PMID: 30317539.
Aromatase and estrogen receptor immunoreactivity in the coronary arteries of monkeys and human subjects.Diano S, Horvath TL, Mor G, Register T, Adams M, Harada N, Naftolin F. Menopause. 2018 Nov. PMID: 30358714.
Metabolism and mitochondria in polycystic kidney disease research and therapy.Padovano V, Podrini C, Boletta A, Caplan MJ. Nat Rev Nephrol. 2018 Nov. PMID: 30120380.
Organisms with alternative genetic codes resolve unassigned codons via mistranslation and ribosomal rescue.Ma NJ, Hemez CF, Barber KW, Rinehart J, Isaacs FJ. Elife. 2018 Oct 30; 2018 Oct 30. PMID: 30375330.
Sparsened neuronal activity in an optogenetically activated olfactory glomerulus.Braubach O, Tombaz T, Geiller T, Homma R, Bozza T, Cohen LB, Choi Y. Sci Rep. 2018 Oct 8; 2018 Oct 8. PMID: 30297851.
A Dexterous, Glove-Based Teleoperable Low-Power Soft Robotic Arm for Delicate Deep-Sea Biological Exploration.Phillips BT, Becker KP, Kurumaya S, Galloway KC, Whittredge G, Vogt DM, Teeple CB, Rosen MH, Pieribone VA, Gruber DF, Wood RJ. Sci Rep. 2018 Oct 3; 2018 Oct 3. PMID: 30283051.
Regulation of renal Na transporters in response to dietary K.Yang L, Xu S, Guo X, Uchida S, Weinstein AM, Wang T, Palmer LG. Am J Physiol Renal Physiol. 2018 Oct 1; 2018 Jun 20. PMID: 29923764.
Mitochondrial Dynamics and Hypothalamic Regulation of Metabolism.Jin S, Diano S. Endocrinology. 2018 Oct 1. PMID: 30203064.
Somatosensory Neurons Enter a State of Altered Excitability during Hibernation.Hoffstaetter LJ, Mastrotto M, Merriman DK, Dib-Hajj SD, Waxman SG, Bagriantsev SN, Gracheva EO. Curr Biol. 2018 Sep 24; 2018 Aug 30. PMID: 30174191.
Phenomic Impact of Genetically-Determined Euthyroid Function and Molecular Differences between Thyroid Disorders.Ravera S, Carrasco N, Gelernter J, Polimanti R. J Clin Med. 2018 Sep 21; 2018 Sep 21. PMID: 30248900.
PKCε contributes to lipid-induced insulin resistance through cross talk with p70S6K and through previously unknown regulators of insulin signaling.Gassaway BM, Petersen MC, Surovtseva YV, Barber KW, Sheetz JB, Aerni HR, Merkel JS, Samuel VT, Shulman GI, Rinehart J. Proc Natl Acad Sci U S A. 2018 Sep 18; 2018 Sep 4. PMID: 30181290.
Synthesis, pharmacology and preclinical evaluation of ¹¹C-labeled 1,3-dihydro-2H-benzo[d]imidazole-2-ones for imaging γ8-dependent transmembrane AMPA receptor regulatory protein.Chen Z, Mori W, Zhang X, Yamasaki T, Dunn PJ, Zhang G, Fu H, Shao T, Zhang Y, Hatori A, Ma L, Fujinaga M, Xie L, Deng X, Li H, Yu Q, Rong J, Josephson L, Ma JA, Shao Y, Tomita S, Zhang MR, Liang SH. Eur J Med Chem. 2018 Sep 5; 2018 Aug 9. PMID: 30145376.
Parvalbumin expression affects synaptic development and physiology at the Drosophila larval NMJ.He T, Nitabach MN, Lnenicka GA. J Neurogenet. 2018 Sep; 2018 Sep 3. PMID: 30175644.
NCK-dependent pericyte migration promotes pathological neovascularization in ischemic retinopathy.Dubrac A, Künzel SE, Künzel SH, Li J, Chandran RR, Martin K, Greif DM, Adams RH, Eichmann A. Nat Commun. 2018 Aug 27; 2018 Aug 27. PMID: 30150707.
Lacteal junction zippering protects against diet-induced obesity.Zhang F, Zarkada G, Han J, Li J, Dubrac A, Ola R, Genet G, Boyé K, Michon P, Künzel SE, Camporez JP, Singh AK, Fong GH, Simons M, Tso P, Fernández-Hernando C, Shulman GI, Sessa WC, Eichmann A. Science. 2018 Aug 10. PMID: 30093598.
Kinase Substrate Profiling Using a Proteome-wide Serine-Oriented Human Peptide Library.Barber KW, Miller CJ, Jun JW, Lou HJ, Turk BE, Rinehart J. Biochemistry. 2018 Aug 7; 2018 Jun 19. PMID: 29920078.
Encoding human serine phosphopeptides in bacteria for proteome-wide identification of phosphorylation-dependent interactions.Barber KW, Muir P, Szeligowski RV, Rogulina S, Gerstein M, Sampson JR, Isaacs FJ, Rinehart J. Nat Biotechnol. 2018 Aug; 2018 Jun 11. PMID: 29889213.
Restoration of vision after de novo genesis of rod photoreceptors in mammalian retinas.Yao K, Qiu S, Wang YV, Park SJH, Mohns EJ, Mehta B, Liu X, Chang B, Zenisek D, Crair MC, Demb JB, Chen B. Nature. 2018 Aug; 2018 Aug 15. PMID: 30111842.
Implications of AMPK in the Formation of Epithelial Tight Junctions.Rowart P, Wu J, Caplan MJ, Jouret F. Int J Mol Sci. 2018 Jul 13; 2018 Jul 13. PMID: 30011834.
Communication: Potassium Channels Define the Dialect.Gracheva EO, Bagriantsev SN. Curr Biol. 2018 Jul 9. PMID: 29990457.
A new brain circuit in feeding control.Diano S. Science. 2018 Jul 6. PMID: 29976812.
Genetically encoded fluorescent voltage indicators: are we there yet?Platisa J, Pieribone VA. Curr Opin Neurobiol. 2018 Jun; 2018 Mar 20. PMID: 29501950.
NFE2-Related Transcription Factor 2 Coordinates Antioxidant Defense with Thyroglobulin Production and Iodination in the Thyroid Gland.Ziros PG, Habeos IG, Chartoumpekis DV, Ntalampyra E, Somm E, Renaud CO, Bongiovanni M, Trougakos IP, Yamamoto M, Kensler TW, Santisteban P, Carrasco N, Ris-Stalpers C, Amendola E, Liao XH, Rossich L, Thomasz L, Juvenal GJ, Refetoff S, Sykiotis GP. Thyroid. 2018 Jun. PMID: 29742982.
Peptide-Mediated Neurotransmission Takes Center Stage.Gonzalez-Suarez AD, Nitabach MN. Trends Neurosci. 2018 Jun. PMID: 29801523.
Monitoring voltage fluctuations of intracellular membranes.Sepehri Rad M, Cohen LB, Braubach O, Baker BJ. Sci Rep. 2018 May 2; 2018 May 2. PMID: 29720664.
Optimizing recruitment and retention of adolescents in ED research: Findings from concussion biomarker pilot study.Mbachu SN, Pieribone VA, Bechtel KA, McCarthy ML, Melnick ER. Am J Emerg Med. 2018 May; 2017 Sep 14. PMID: 28918968.
Unexplored therapeutic opportunities in the human genome.Oprea TI, Bologa CG, Brunak S, Campbell A, Gan GN, Gaulton A, Gomez SM, Guha R, Hersey A, Holmes J, Jadhav A, Jensen LJ, Johnson GL, Karlson A, Leach AR, Ma'ayan A, Malovannaya A, Mani S, Mathias SL, McManus MT, Meehan TF, von Mering C, Muthas D, Nguyen DT, Overington JP, Papadatos G, Qin J, Reich C, Roth BL, Schürer SC, Simeonov A, Sklar LA, Southall N, Tomita S, Tudose I, Ursu O, Vidovic D, Waller A, Westergaard D, Yang JJ, Zahoránszky-Köhalmi G. Nat Rev Drug Discov. 2018 May; 2018 Mar 23. PMID: 29472638.
TRPs et al.: a molecular toolkit for thermosensory adaptations.Hoffstaetter LJ, Bagriantsev SN, Gracheva EO. Pflugers Arch. 2018 May; 2018 Feb 27. PMID: 29484488.
TMEM150C/Tentonin3 Is a Regulator of Mechano-gated Ion Channels.Anderson EO, Schneider ER, Matson JD, Gracheva EO, Bagriantsev SN. Cell Rep. 2018 Apr 17. PMID: 29669276.
Prolyl carboxypeptidase in Agouti-related Peptide neurons modulates food intake and body weight.Bruschetta G, Jin S, Kim JD, Diano S. Mol Metab. 2018 Apr; 2018 Feb 8. PMID: 29459251.
Daily oscillations in expression and responsiveness of Toll-like receptors in splenic immune cells.Silver AC, Buckley SM, Hughes ME, Hastings AK, Nitabach MN, Fikrig E. Heliyon. 2018 Mar; 2018 Mar 20. PMID: 29862343.
Urinary bladder hypertrophy characteristic of male ROMK Bartter's mice does not occur in female mice.Kim JM, Xu S, Guo X, Hu H, Dong K, Wang T. Am J Physiol Regul Integr Comp Physiol. 2018 Mar 1; 2017 Nov 1. PMID: 29092859.
La-related protein 1 (LARP1) repression of TOP mRNA translation is mediated through its cap-binding domain and controlled by an adjacent regulatory region.Philippe L, Vasseur JJ, Debart F, Thoreen CC. Nucleic Acids Res. 2018 Feb 16. PMID: 29244122.
The ABCs of PTMs.Barber KW, Rinehart J. Nat Chem Biol. 2018 Feb 14. PMID: 29443972.
On the Path from Proteomics to Function: GABA_AR Trafficking Takes a Turn.Noam Y, Tomita S. Neuron. 2018 Feb 7. PMID: 29420928.
Input-Specific NMDAR-Dependent Potentiation of Dendritic GABAergic Inhibition.Chiu CQ, Martenson JS, Yamazaki M, Natsume R, Sakimura K, Tomita S, Tavalin SJ, Higley MJ. Neuron. 2018 Jan 17. PMID: 29346754.

2017

Molecular Prerequisites for Diminished Cold Sensitivity in Ground Squirrels and Hamsters.Matos-Cruz V, Schneider ER, Mastrotto M, Merriman DK, Bagriantsev SN, Gracheva EO. Cell Rep. 2017 Dec 19. PMID: 29262313.
Molecular basis of tactile specialization in the duck bill.Schneider ER, Anderson EO, Mastrotto M, Matson JD, Schulz VP, Gallagher PG, LaMotte RH, Gracheva EO, Bagriantsev SN. Proc Natl Acad Sci U S A. 2017 Dec 5; 2017 Nov 6. PMID: 29109250.
Development and plasticity of meningeal lymphatic vessels.Antila S, Karaman S, Nurmi H, Airavaara M, Voutilainen MH, Mathivet T, Chilov D, Li Z, Koppinen T, Park JH, Fang S, Aspelund A, Saarma M, Eichmann A, Thomas JL, Alitalo K. J Exp Med. 2017 Dec 4; 2017 Nov 15. PMID: 29141865.
Voltage and Calcium Imaging of Brain Activity.Sepehri Rad M, Choi Y, Cohen LB, Baker BJ, Zhong S, Storace DA, Braubach OR. Biophys J. 2017 Nov 21; 2017 Nov 1. PMID: 29102396.
MS-READ: Quantitative measurement of amino acid incorporation.Mohler K, Aerni HR, Gassaway B, Ling J, Ibba M, Rinehart J. Biochim Biophys Acta Gen Subj. 2017 Nov; 2017 Jan 24. PMID: 28130155.
Single-molecule force spectroscopy of protein-membrane interactions.Ma L, Cai Y, Li Y, Jiao J, Wu Z, O'Shaughnessy B, De Camilli P, Karatekin E, Zhang Y. Elife. 2017 Oct 30; 2017 Oct 30. PMID: 29083305.
Pathogenesis of hypothyroidism-induced NAFLD is driven by intra- and extrahepatic mechanisms.Ferrandino G, Kaspari RR, Spadaro O, Reyna-Neyra A, Perry RJ, Cardone R, Kibbey RG, Shulman GI, Dixit VD, Carrasco N. Proc Natl Acad Sci U S A. 2017 Oct 24; 2017 Oct 10. PMID: 29073114.
Novel mechanisms of PIEZO1 dysfunction in hereditary xerocytosis.Glogowska E, Schneider ER, Maksimova Y, Schulz VP, Lezon-Geyda K, Wu J, Radhakrishnan K, Keel SB, Mahoney D, Freidmann AM, Altura RA, Gracheva EO, Bagriantsev SN, Kalfa TA, Gallagher PG. Blood. 2017 Oct 19; 2017 Jul 17. PMID: 28716860.
Comparative Proteomics Enables Identification of Nonannotated Cold Shock Proteins in E. coli.D'Lima NG, Khitun A, Rosenbloom AD, Yuan P, Gassaway BM, Barber KW, Rinehart J, Slavoff SA. J Proteome Res. 2017 Oct 6; 2017 Sep 19. PMID: 28861998.
Guidelines for Genome-Scale Analysis of Biological Rhythms.Hughes ME, Abruzzi KC, Allada R, Anafi R, Arpat AB, Asher G, Baldi P, de Bekker C, Bell-Pedersen D, Blau J, Brown S, Ceriani MF, Chen Z, Chiu JC, Cox J, Crowell AM, DeBruyne JP, Dijk DJ, DiTacchio L, Doyle FJ, Duffield GE, Dunlap JC, Eckel-Mahan K, Esser KA, FitzGerald GA, Forger DB, Francey LJ, Fu YH, Gachon F, Gatfield D, de Goede P, Golden SS, Green C, Harer J, Harmer S, Haspel J, Hastings MH, Herzel H, Herzog ED, Hoffmann C, Hong C, Hughey JJ, Hurley JM, de la Iglesia HO, Johnson C, Kay SA, Koike N, Kornacker K, Kramer A, Lamia K, Leise T, Lewis SA, Li J, Li X, Liu AC, Loros JJ, Martino TA, Menet JS, Merrow M, Millar AJ, Mockler T, Naef F, Nagoshi E, Nitabach MN, Olmedo M, Nusinow DA, Ptáček LJ, Rand D, Reddy AB, Robles MS, Roenneberg T, Rosbash M, Ruben MD, Rund SSC, Sancar A, Sassone-Corsi P, Sehgal A, Sherrill-Mix S, Skene DJ, Storch KF, Takahashi JS, Ueda HR, Wang H, Weitz C, Westermark PO, Wijnen H, Xu Y, Wu G, Yoo SH, Young M, Zhang EE, Zielinski T, Hogenesch JB. J Biol Rhythms. 2017 Oct; 2017 Nov 3. PMID: 29098954.
Heterogeneity of Stop Codon Readthrough in Single Bacterial Cells and Implications for Population Fitness.Fan Y, Evans CR, Barber KW, Banerjee K, Weiss KJ, Margolin W, Igoshin OA, Rinehart J, Ling J. Mol Cell. 2017 Sep 7; 2017 Aug 3. PMID: 28781237.
Basic research: Where do new endothelial cells come from in the injured heart?Greif DM, Eichmann A. Nat Rev Cardiol. 2017 Sep; 2017 Aug 3. PMID: 28770866.
Assembly rules for GABA_A receptor complexes in the brain.Martenson JS, Yamasaki T, Chaudhury NH, Albrecht D, Tomita S. Elife. 2017 Aug 17; 2017 Aug 17. PMID: 28816653.
Gender difference in kidney electrolyte transport. I. Role of AT_1a receptor in thiazide-sensitive Na⁺-Cl^- cotransporter activity and expression in male and female mice.Li J, Hatano R, Xu S, Wan L, Yang L, Weinstein AM, Palmer L, Wang T. Am J Physiol Renal Physiol. 2017 Aug 1; 2017 May 31. PMID: 28566500.
Editorial overview: Molecular neuroscience 2017.Tomita S, Bloodgood BL. Curr Opin Neurobiol. 2017 Aug; 2017 Jul 20. PMID: 28736237.
Hypothalamic Ventromedial Lin28a Enhances Glucose Metabolism in Diet-Induced Obesity.Kim JD, Toda C, Ramírez CM, Fernández-Hernando C, Diano S. Diabetes. 2017 Aug; 2017 May 26. PMID: 28550108.
Plasticity of calcium-permeable AMPA glutamate receptors in Pro-opiomelanocortin neurons.Suyama S, Ralevski A, Liu ZW, Dietrich MO, Yada T, Simonds SE, Cowley MA, Gao XB, Diano S, Horvath TL. Elife. 2017 Aug 1; 2017 Aug 1. PMID: 28762946.
Genetic and neuronal mechanisms governing the sex-specific interaction between sleep and sexual behaviors in Drosophila.Chen D, Sitaraman D, Chen N, Jin X, Han C, Chen J, Sun M, Baker BS, Nitabach MN, Pan Y. Nat Commun. 2017 Jul 28; 2017 Jul 28. PMID: 28754889.
Measuring the olfactory bulb input-output transformation reveals a contribution to the perception of odorant concentration invariance.Storace DA, Cohen LB. Nat Commun. 2017 Jul 19; 2017 Jul 19. PMID: 28724907.
An extremely high dietary iodide supply forestalls severe hypothyroidism in Na⁺/I^- symporter (NIS) knockout mice.Ferrandino G, Kaspari RR, Reyna-Neyra A, Boutagy NE, Sinusas AJ, Carrasco N. Sci Rep. 2017 Jul 13; 2017 Jul 13. PMID: 28706256.
A Peptidergic Circuit Links the Circadian Clock to Locomotor Activity.King AN, Barber AF, Smith AE, Dreyer AP, Sitaraman D, Nitabach MN, Cavanaugh DJ, Sehgal A. Curr Biol. 2017 Jul 10; 2017 Jun 29. PMID: 28669757.
Sex at Atomic Resolution.Hwang JY, Chung JJ. Cell. 2017 Jun 15. PMID: 28622504.
Regulation of glomerulotubular balance: flow-activated proximal tubule function.Wang T, Weinbaum S, Weinstein AM. Pflugers Arch. 2017 Jun; 2017 Mar 7. PMID: 28271233.
Entropic forces drive self-organization and membrane fusion by SNARE proteins.Mostafavi H, Thiyagarajan S, Stratton BS, Karatekin E, Warner JM, Rothman JE, O'Shaughnessy B. Proc Natl Acad Sci U S A. 2017 May 23; 2017 May 10. PMID: 28490503.
FGF-dependent metabolic control of vascular development.Yu P, Wilhelm K, Dubrac A, Tung JK, Alves TC, Fang JS, Xie Y, Zhu J, Chen Z, De Smet F, Zhang J, Jin SW, Sun L, Sun H, Kibbey RG, Hirschi KK, Hay N, Carmeliet P, Chittenden TW, Eichmann A, Potente M, Simons M. Nature. 2017 May 11; 2017 May 3. PMID: 28467822.
mTORC1 Balances Cellular Amino Acid Supply with Demand for Protein Synthesis through Post-transcriptional Control of ATF4.Park Y, Reyna-Neyra A, Philippe L, Thoreen CC. Cell Rep. 2017 May 9. PMID: 28494858.
Membrane Currents, Gene Expression, and Circadian Clocks.Allen CN, Nitabach MN, Colwell CS. Cold Spring Harb Perspect Biol. 2017 May 1; 2017 May 1. PMID: 28246182.
Kidney Tubular Ablation of Ocrl/Inpp5b Phenocopies Lowe Syndrome Tubulopathy.Inoue K, Balkin DM, Liu L, Nandez R, Wu Y, Tian X, Wang T, Nussbaum R, De Camilli P, Ishibe S. J Am Soc Nephrol. 2017 May; 2016 Nov 28. PMID: 27895154.
Editing of misaminoacylated tRNA controls the sensitivity of amino acid stress responses in Saccharomyces cerevisiae.Mohler K, Mann R, Bullwinkle TJ, Hopkins K, Hwang L, Reynolds NM, Gassaway B, Aerni HR, Rinehart J, Polymenis M, Faull K, Ibba M. Nucleic Acids Res. 2017 Apr 20. PMID: 28168297.
Current carried by the Slc26 family member prestin does not flow through the transporter pathway.Bai JP, Moeini-Naghani I, Zhong S, Li FY, Bian S, Sigworth FJ, Santos-Sacchi J, Navaratnam D. Sci Rep. 2017 Apr 19; 2017 Apr 19. PMID: 28422190.
Alk2/ACVR1 and Alk3/BMPR1A Provide Essential Function for Bone Morphogenetic Protein-Induced Retinal Angiogenesis.Lee HW, Chong DC, Ola R, Dunworth WP, Meadows S, Ka J, Kaartinen VM, Qyang Y, Cleaver O, Bautch VL, Eichmann A, Jin SW. Arterioscler Thromb Vasc Biol. 2017 Apr; 2017 Feb 23. PMID: 28232325.
Multisensory integration in C. elegans.Ghosh DD, Nitabach MN, Zhang Y, Harris G. Curr Opin Neurobiol. 2017 Apr; 2017 Mar 6. PMID: 28273525.
Dilation of fusion pores by crowding of SNARE proteins.Wu Z, Bello OD, Thiyagarajan S, Auclair SM, Vennekate W, Krishnakumar SS, O'Shaughnessy B, Karatekin E. Elife. 2017 Mar 27; 2017 Mar 27. PMID: 28346138.
Genome mining unearths a hybrid nonribosomal peptide synthetase-like-pteridine synthase biosynthetic gene cluster.Park HB, Perez CE, Barber KW, Rinehart J, Crawford JM. Elife. 2017 Mar 15; 2017 Mar 15. PMID: 28431213.
GARLH Family Proteins Stabilize GABA_A Receptors at Synapses.Yamasaki T, Hoyos-Ramirez E, Martenson JS, Morimoto-Tomita M, Tomita S. Neuron. 2017 Mar 8. PMID: 28279354.
DRP1 Suppresses Leptin and Glucose Sensing of POMC Neurons.Santoro A, Campolo M, Liu C, Sesaki H, Meli R, Liu ZW, Kim JD, Diano S. Cell Metab. 2017 Mar 7; 2017 Feb 9. PMID: 28190775.
Conformational dynamics of a neurotransmitter:sodium symporter in a lipid bilayer.Adhikary S, Deredge DJ, Nagarajan A, Forrest LR, Wintrode PL, Singh SK. Proc Natl Acad Sci U S A. 2017 Mar 7; 2017 Feb 21. PMID: 28223522.
CatSperζ regulates the structural continuity of sperm Ca²⁺ signaling domains and is required for normal fertility.Chung JJ, Miki K, Kim D, Shim SH, Shi HF, Hwang JY, Cai X, Iseri Y, Zhuang X, Clapham DE. Elife. 2017 Feb 23; 2017 Feb 23. PMID: 28226241.
POMC Neurons: From Birth to Death.Toda C, Santoro A, Kim JD, Diano S. Annu Rev Physiol. 2017 Feb 10. PMID: 28192062.
The Sodium/Iodide Symporter (NIS): Molecular Physiology and Preclinical and Clinical Applications.Ravera S, Reyna-Neyra A, Ferrandino G, Amzel LM, Carrasco N. Annu Rev Physiol. 2017 Feb 10. PMID: 28192058.
The molecular basis of mTORC1-regulated translation.Thoreen CC. Biochem Soc Trans. 2017 Feb 8. PMID: 28202675.
Phosphorylation by PKC and PKA regulate the kinase activity and downstream signaling of WNK4.Castañeda-Bueno M, Arroyo JP, Zhang J, Puthumana J, Yarborough O 3rd, Shibata S, Rojas-Vega L, Gamba G, Rinehart J, Lifton RP. Proc Natl Acad Sci U S A. 2017 Jan 31; 2017 Jan 17. PMID: 28096417.
The secretory pathway at 50: a golden anniversary for some momentous grains of silver.Matlin KS, Caplan MJ. Mol Biol Cell. 2017 Jan 15. PMID: 28082520.
The polycystins are modulated by cellular oxygen-sensing pathways and regulate mitochondrial function.Padovano V, Kuo IY, Stavola LK, Aerni HR, Flaherty BJ, Chapin HC, Ma M, Somlo S, Boletta A, Ehrlich BE, Rinehart J, Caplan MJ. Mol Biol Cell. 2017 Jan 15; 2016 Nov 23. PMID: 27881662.

2016

Biconcave shape of human red-blood-cell ghosts relies on density differences between the rim and dimple of the ghost's plasma membrane.Hoffman JF. Proc Natl Acad Sci U S A. 2016 Dec 20; 2016 Dec 5. PMID: 27930321.
Neural Architecture of Hunger-Dependent Multisensory Decision Making in C. elegans.Ghosh DD, Sanders T, Hong S, McCurdy LY, Chase DL, Cohen N, Koelle MR, Nitabach MN. Neuron. 2016 Dec 7; 2016 Nov 17. PMID: 27866800.
Newly synthesized and recycling pools of the apical protein gp135 do not occupy the same compartments.Stoops EH, Hull M, Caplan MJ. Traffic. 2016 Dec; 2016 Nov 1. PMID: 27649479.
PI3 kinase inhibition improves vascular malformations in mouse models of hereditary haemorrhagic telangiectasia.Ola R, Dubrac A, Han J, Zhang F, Fang JS, Larrivée B, Lee M, Urarte AA, Kraehling JR, Genet G, Hirschi KK, Sessa WC, Canals FV, Graupera M, Yan M, Young LH, Oh PS, Eichmann A. Nat Commun. 2016 Nov 29; 2016 Nov 29. PMID: 27897192.
The Robo4 cytoplasmic domain is dispensable for vascular permeability and neovascularization.Zhang F, Prahst C, Mathivet T, Pibouin-Fragner L, Zhang J, Genet G, Tong R, Dubrac A, Eichmann A. Nat Commun. 2016 Nov 24; 2016 Nov 24. PMID: 27882935.
Genome-wide RNAi screen reveals ALK1 mediates LDL uptake and transcytosis in endothelial cells.Kraehling JR, Chidlow JH, Rajagopal C, Sugiyama MG, Fowler JW, Lee MY, Zhang X, Ramírez CM, Park EJ, Tao B, Chen K, Kuruvilla L, Larriveé B, Folta-Stogniew E, Ola R, Rotllan N, Zhou W, Nagle MW, Herz J, Williams KJ, Eichmann A, Lee WL, Fernández-Hernando C, Sessa WC. Nat Commun. 2016 Nov 21; 2016 Nov 21. PMID: 27869117.
Potassium Channelopathies and Gastrointestinal Ulceration.Han J, Lee SH, Giebisch G, Wang T. Gut Liver. 2016 Nov 15. PMID: 27784845.
CaMKII Phosphorylation of TARPγ-8 Is a Mediator of LTP and Learning and Memory.Park J, Chávez AE, Mineur YS, Morimoto-Tomita M, Lutzu S, Kim KS, Picciotto MR, Castillo PE, Tomita S. Neuron. 2016 Oct 5; 2016 Sep 22. PMID: 27667007.
Low-cost functional plasticity of TRPV1 supports heat tolerance in squirrels and camels.Laursen WJ, Schneider ER, Merriman DK, Bagriantsev SN, Gracheva EO. Proc Natl Acad Sci U S A. 2016 Oct 4; 2016 Sep 16. PMID: 27638213.
Sugar-coated sperm.Chung JJ. Mol Reprod Dev. 2016 Oct. PMID: 27591546.
Defective fluid shear stress mechanotransduction mediates hereditary hemorrhagic telangiectasia.Baeyens N, Larrivée B, Ola R, Hayward-Piatkowskyi B, Dubrac A, Huang B, Ross TD, Coon BG, Min E, Tsarfati M, Tong H, Eichmann A, Schwartz MA. J Cell Biol. 2016 Sep 26; 2016 Sep 19. PMID: 27646277.
Hypothalamic and pituitary expression of ghrelin receptor message is increased during lactation.Abizaid A, Schioavo L, Diano S. Neurosci Lett. 2016 Sep 19. PMID: 27642155.
Na+ coordination at the Na2 site of the Na+/I- symporter.Ferrandino G, Nicola JP, Sánchez YE, Echeverria I, Liu Y, Amzel LM, Carrasco N. Proc Natl Acad Sci U S A. 2016 Sep 13; 2016 Aug 25. PMID: 27562170.
SPAK and OSR1 play essential roles in potassium homeostasis through actions on the distal convoluted tubule.Ferdaus MZ, Barber KW, López-Cayuqueo KI, Terker AS, Argaiz ER, Gassaway BM, Chambrey R, Gamba G, Rinehart J, McCormick JA. J Physiol. 2016 Sep 1; 2016 May 29. PMID: 27068441.
BMP9/ALK1 inhibits neovascularization in mouse models of age-related macular degeneration.Ntumba K, Akla N, Oh SP, Eichmann A, Larrivée B. Oncotarget. 2016 Aug 30. PMID: 27517154.
SNARE-mediated Fusion of Single Proteoliposomes with Tethered Supported Bilayers in a Microfluidic Flow Cell Monitored by Polarized TIRF Microscopy.Nikolaus J, Karatekin E. J Vis Exp. 2016 Aug 24; 2016 Aug 24. PMID: 27585113.
Regression of experimental NIS-expressing breast cancer brain metastases in response to radioiodide/gemcitabine dual therapy.Renier C, Do J, Reyna-Neyra A, Foster D, De A, Vogel H, Jeffrey SS, Tse V, Carrasco N, Wapnir I. Oncotarget. 2016 Aug 23. PMID: 27363025.
Sympathetic Innervation Promotes Arterial Fate by Enhancing Endothelial ERK Activity.Pardanaud L, Pibouin-Fragner L, Dubrac A, Mathivet T, English I, Brunet I, Simons M, Eichmann A. Circ Res. 2016 Aug 19; 2016 Jun 27. PMID: 27354211.
Artificial bacterial biomimetic nanoparticles synergize pathogen-associated molecular patterns for vaccine efficacy.Siefert AL, Caplan MJ, Fahmy TM. Biomaterials. 2016 Aug; 2016 Apr 1. PMID: 27162077.
Investigation of peanut oral immunotherapy with CpG/peanut nanoparticles in a murine model of peanut allergy.Srivastava KD, Siefert A, Fahmy TM, Caplan MJ, Li XM, Sampson HA. J Allergy Clin Immunol. 2016 Aug; 2016 Apr 26. PMID: 27130858.
Distinct Subunit Domains Govern Synaptic Stability and Specificity of the Kainate Receptor.Straub C, Noam Y, Nomura T, Yamasaki M, Yan D, Fernandes HB, Zhang P, Howe JR, Watanabe M, Contractor A, Tomita S. Cell Rep. 2016 Jul 12; 2016 Jun 23. PMID: 27346345.
Synaptic Ribbons Require Ribeye for Electron Density, Proper Synaptic Localization, and Recruitment of Calcium Channels.Lv C, Stewart WJ, Akanyeti O, Frederick C, Zhu J, Santos-Sacchi J, Sheets L, Liao JC, Zenisek D. Cell Rep. 2016 Jun 21; 2016 Jun 9. PMID: 27292637.
Nanodisc-cell fusion: control of fusion pore nucleation and lifetimes by SNARE protein transmembrane domains.Wu Z, Auclair SM, Bello O, Vennekate W, Dudzinski NR, Krishnakumar SS, Karatekin E. Sci Rep. 2016 Jun 6; 2016 Jun 6. PMID: 27264104.
The tail of polycystin-1 pays the kidney a complement.Caplan MJ. Am J Physiol Renal Physiol. 2016 Jun 1; 2016 Mar 23. PMID: 27009337.
Long noncoding RNAs in psychiatric disorders.Zuo L, Tan Y, Wang Z, Wang KS, Zhang X, Chen X, Li CS, Wang T, Luo X. Psychiatr Genet. 2016 Jun. PMID: 26974119.
Netrin-1 Regulates Fibrocyte Accumulation in the Decellularized Fibrotic Sclerodermatous Lung Microenvironment and in Bleomycin-Induced Pulmonary Fibrosis.Sun H, Zhu Y, Pan H, Chen X, Balestrini JL, Lam TT, Kanyo JE, Eichmann A, Gulati M, Fares WH, Bai H, Feghali-Bostwick CA, Gan Y, Peng X, Moore MW, White ES, Sava P, Gonzalez AL, Cheng Y, Niklason LE, Herzog EL. Arthritis Rheumatol. 2016 May. PMID: 26749424.
Evolutionary Specialization of Tactile Perception in Vertebrates.Schneider ER, Gracheva EO, Bagriantsev SN. Physiology (Bethesda). 2016 May. PMID: 27053733.
Toward Better Genetically Encoded Sensors of Membrane Potential.Storace D, Sepehri Rad M, Kang B, Cohen LB, Hughes T, Baker BJ. Trends Neurosci. 2016 May. PMID: 27130905.
Unconventional endocannabinoid signaling governs sperm activation via the sex hormone progesterone.Miller MR, Mannowetz N, Iavarone AT, Safavi R, Gracheva EO, Smith JF, Hill RZ, Bautista DM, Kirichok Y, Lishko PV. Science. 2016 Apr 29; 2016 Mar 17. PMID: 26989199.
Function and regulation of TRPP2 ion channel revealed by a gain-of-function mutant.Arif Pavel M, Lv C, Ng C, Yang L, Kashyap P, Lam C, Valentino V, Fung HY, Campbell T, Møller SG, Zenisek D, Holtzman NG, Yu Y. Proc Natl Acad Sci U S A. 2016 Apr 26; 2016 Apr 11. PMID: 27071085.
Biofluorescence in Catsharks (Scyliorhinidae): Fundamental Description and Relevance for Elasmobranch Visual Ecology.Gruber DF, Loew ER, Deheyn DD, Akkaynak D, Gaffney JP, Smith WL, Davis MP, Stern JH, Pieribone VA, Sparks JS. Sci Rep. 2016 Apr 25; 2016 Apr 25. PMID: 27109385.
2016 Robert W. Berliner Award for Excellence in Renal Physiology.Caplan MJ. Am J Physiol Renal Physiol. 2016 Apr 15; 2016 Mar 9. PMID: 26962101.
Cholesterol Increases the Openness of SNARE-Mediated Flickering Fusion Pores.Stratton BS, Warner JM, Wu Z, Nikolaus J, Wei G, Wagnon E, Baddeley D, Karatekin E, O'Shaughnessy B. Biophys J. 2016 Apr 12. PMID: 27074679.
Statistical modeling and removal of lipid membrane projections for cryo-EM structure determination of reconstituted membrane proteins.Jensen KH, Brandt SS, Shigematsu H, Sigworth FJ. J Struct Biol. 2016 Apr; 2016 Feb 1. PMID: 26835990.
Mechanism of Paroxetine (Paxil) Inhibition of the Serotonin Transporter.Davis BA, Nagarajan A, Forrest LR, Singh SK. Sci Rep. 2016 Apr 1; 2016 Apr 1. PMID: 27032980.
Romk1 Knockout Mice Do Not Produce Bartter Phenotype but Exhibit Impaired K Excretion.Dong K, Yan Q, Lu M, Wan L, Hu H, Guo J, Boulpaep E, Wang W, Giebisch G, Hebert SC, Wang T. J Biol Chem. 2016 Mar 4; 2016 Jan 4. PMID: 26728465.
Prolyl Endopeptidase (PREP) is Associated With Male Reproductive Functions and Gamete Physiology in Mice.Dotolo R, Kim JD, Pariante P, Minucci S, Diano S. J Cell Physiol. 2016 Mar; 2015 Sep 18. PMID: 26332268.
Dickkopf-related Protein 3 as a Sensitive and Specific Marker for Cerebrospinal Fluid Leaks.Michaelides EM, Kuang H, Pieribone VA. Otol Neurotol. 2016 Mar. PMID: 26837002.
UCP2 Regulates Mitochondrial Fission and Ventromedial Nucleus Control of Glucose Responsiveness.Toda C, Kim JD, Impellizzeri D, Cuzzocrea S, Liu ZW, Diano S. Cell. 2016 Feb 25. PMID: 26919426.
A Bright and Fast Red Fluorescent Protein Voltage Indicator That Reports Neuronal Activity in Organotypic Brain Slices.Abdelfattah AS, Farhi SL, Zhao Y, Brinks D, Zou P, Ruangkittisakul A, Platisa J, Pieribone VA, Ballanyi K, Cohen AE, Campbell RE. J Neurosci. 2016 Feb 24. PMID: 26911693.
miR-182 Modulates Myocardial Hypertrophic Response Induced by Angiogenesis in Heart.Li N, Hwangbo C, Jaba IM, Zhang J, Papangeli I, Han J, Mikush N, Larrivée B, Eichmann A, Chun HJ, Young LH, Tirziu D. Sci Rep. 2016 Feb 18; 2016 Feb 18. PMID: 26888314.
Porcupine Controls Hippocampal AMPAR Levels, Composition, and Synaptic Transmission.Erlenhardt N, Yu H, Abiraman K, Yamasaki T, Wadiche JI, Tomita S, Bredt DS. Cell Rep. 2016 Feb 2; 2016 Jan 14. PMID: 26776514.
Principles of cryo-EM single-particle image processing.Sigworth FJ. Microscopy (Oxf). 2016 Feb; 2015 Dec 24. PMID: 26705325.
Targeting NCK-Mediated Endothelial Cell Front-Rear Polarity Inhibits Neovascularization.Dubrac A, Genet G, Ola R, Zhang F, Pibouin-Fragner L, Han J, Zhang J, Thomas JL, Chedotal A, Schwartz MA, Eichmann A. Circulation. 2016 Jan 26; 2015 Dec 9. PMID: 26659946.

2015

Sex difference of autosomal alleles in populations of European and African descent.Zuo L, Wang T, Lin X, Wang J, Tan Y, Wang X, Yu X, Luo X. Genes Genomics. 2015 Dec 1; 2015 Sep 3. PMID: 26702338.
Dual pulse-chase microscopy reveals early divergence in the biosynthetic trafficking of the Na,K-ATPase and E-cadherin.Farr GA, Hull M, Stoops EH, Bateson R, Caplan MJ. Mol Biol Cell. 2015 Dec 1; 2015 Sep 30. PMID: 26424804.
Evolution of translation machinery in recoded bacteria enables multi-site incorporation of nonstandard amino acids.Amiram M, Haimovich AD, Fan C, Wang YS, Aerni HR, Ntai I, Moonan DW, Ma NJ, Rovner AJ, Hong SH, Kelleher NL, Goodman AL, Jewett MC, Söll D, Rinehart J, Isaacs FJ. Nat Biotechnol. 2015 Dec; 2015 Nov 16. PMID: 26571098.
A structural model for facultative anion channels in an oligomeric membrane protein: the yeast TRK (K(+)) system.Pardo JP, González-Andrade M, Allen K, Kuroda T, Slayman CL, Rivetta A. Pflugers Arch. 2015 Dec; 2015 Jun 24. PMID: 26100673.
Propagation of Homeostatic Sleep Signals by Segregated Synaptic Microcircuits of the Drosophila Mushroom Body.Sitaraman D, Aso Y, Jin X, Chen N, Felix M, Rubin GM, Nitabach MN. Curr Biol. 2015 Nov 16; 2015 Oct 8. PMID: 26455303.
Akt Substrate of 160 kD Regulates Na+,K+-ATPase Trafficking in Response to Energy Depletion and Renal Ischemia.Alves DS, Thulin G, Loffing J, Kashgarian M, Caplan MJ. J Am Soc Nephrol. 2015 Nov; 2015 Mar 18. PMID: 25788531.
The periciliary ring in polarized epithelial cells is a hot spot for delivery of the apical protein gp135.Stoops EH, Hull M, Olesen C, Mistry K, Harder JL, Rivera-Molina F, Toomre D, Caplan MJ. J Cell Biol. 2015 Oct 26. PMID: 26504168.
AgRP Neurons Regulate Bone Mass.Kim JG, Sun BH, Dietrich MO, Koch M, Yao GQ, Diano S, Insogna K, Horvath TL. Cell Rep. 2015 Oct 6; 2015 Sep 24. PMID: 26411686.
Model of fibrolamellar hepatocellular carcinomas reveals striking enrichment in cancer stem cells.Oikawa T, Wauthier E, Dinh TA, Selitsky SR, Reyna-Neyra A, Carpino G, Levine R, Cardinale V, Klimstra D, Gaudio E, Alvaro D, Carrasco N, Sethupathy P, Reid LM. Nat Commun. 2015 Oct 6; 2015 Oct 6. PMID: 26437858.
Evolutionary adaptation to thermosensation.Gracheva EO, Bagriantsev SN. Curr Opin Neurobiol. 2015 Oct; 2015 Feb 17. PMID: 25698346.
Sodium/Iodide Symporter Mutant V270E Causes Stunted Growth but No Cognitive Deficiency.Nicola JP, Reyna-Neyra A, Saenger P, Rodriguez-Buritica DF, Gamez Godoy JD, Muzumdar R, Amzel LM, Carrasco N. J Clin Endocrinol Metab. 2015 Oct; 2015 Jul 23. PMID: 26204134.
Down-regulation of PRKCB1 expression in Han Chinese patients with subsyndromal symptomatic depression.Guo X, Li Z, Zhang C, Yi Z, Li H, Cao L, Yuan C, Hong W, Wu Z, Peng D, Chen J, Xia W, Zhao G, Wang F, Yu S, Cui D, Xu Y, Golam CM, Smith AK, Wang T, Fang Y. J Psychiatr Res. 2015 Oct; 2015 Jul 17. PMID: 26343587.
The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy.Heo JM, Ordureau A, Paulo JA, Rinehart J, Harper JW. Mol Cell. 2015 Oct 1; 2015 Sep 10. PMID: 26365381.
Robust production of recombinant phosphoproteins using cell-free protein synthesis.Oza JP, Aerni HR, Pirman NL, Barber KW, Ter Haar CM, Rogulina S, Amrofell MB, Isaacs FJ, Rinehart J, Jewett MC. Nat Commun. 2015 Sep 9; 2015 Sep 9. PMID: 26350765.
A flexible codon in genomically recoded Escherichia coli permits programmable protein phosphorylation.Pirman NL, Barber KW, Aerni HR, Ma NJ, Haimovich AD, Rogulina S, Isaacs FJ, Rinehart J. Nat Commun. 2015 Sep 9; 2015 Sep 9. PMID: 26350500.
Chemical and Physical Sensors in the Regulation of Renal Function.Pluznick JL, Caplan MJ. Clin J Am Soc Nephrol. 2015 Sep 4; 2014 Oct 3. PMID: 25280495.
Exploring the Biology of G Protein-Coupled Receptors from In Vitro to In Vivo.Bohn LM, Lohse MJ, Nitabach MN, Taghert PH, Smit MJ. Mol Pharmacol. 2015 Sep; 2015 Jul 10. PMID: 26162863.
Cryo-EM: Spinning the Micelles Away.Singh SK, Sigworth FJ. Structure. 2015 Sep 1. PMID: 26331455.
Chemical Evolution of a Bacterial Proteome.Hoesl MG, Oehm S, Durkin P, Darmon E, Peil L, Aerni HR, Rappsilber J, Rinehart J, Leach D, Söll D, Budisa N. Angew Chem Int Ed Engl. 2015 Aug 17; 2015 Jul 1. PMID: 26136259.
Molecular mechanisms of temperature adaptation.Bagriantsev SN, Gracheva EO. J Physiol. 2015 Aug 15; 2015 Jan 5. PMID: 25433072.
Three myosins contribute uniquely to the assembly and constriction of the fission yeast cytokinetic contractile ring.Laplante C, Berro J, Karatekin E, Hernandez-Leyva A, Lee R, Pollard TD. Curr Biol. 2015 Aug 3; 2015 Jul 2. PMID: 26144970.
Directly reconstructing principal components of heterogeneous particles from cryo-EM images.Tagare HD, Kucukelbir A, Sigworth FJ, Wang H, Rao M. J Struct Biol. 2015 Aug; 2015 Jun 4. PMID: 26049077.
A marginal band of microtubules transports and organizes mitochondria in retinal bipolar synaptic terminals.Graffe M, Zenisek D, Taraska JW. J Gen Physiol. 2015 Jul. PMID: 26123197.
Kir1.1 (ROMK) and Kv7.1 (KCNQ1/KvLQT1) are essential for normal gastric acid secretion: importance of functional Kir1.1.Vucic E, Alfadda T, MacGregor GG, Dong K, Wang T, Geibel JP. Pflugers Arch. 2015 Jul; 2014 Aug 17. PMID: 25127675.
Vascular Mural Cells Promote Noradrenergic Differentiation of Embryonic Sympathetic Neurons.Fortuna V, Pardanaud L, Brunet I, Ola R, Ristori E, Santoro MM, Nicoli S, Eichmann A. Cell Rep. 2015 Jun 23; 2015 Jun 11. PMID: 26074079.
Commentary on "Caged Phosphate and the Slips and Misses in Determination of Quantum Yields for Ultraviolet-A-Induced Photouncaging" by G. Gasser and Co-Workers.Corrie JE, Kaplan JH, Forbush B, Ogden DC, Trentham DR. Chemphyschem. 2015 Jun 22; 2015 Feb 20. PMID: 25704071.
Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch.Aspalter IM, Gordon E, Dubrac A, Ragab A, Narloch J, Vizán P, Geudens I, Collins RT, Franco CA, Abrahams CL, Thurston G, Fruttiger M, Rosewell I, Eichmann A, Gerhardt H. Nat Commun. 2015 Jun 17; 2015 Jun 17. PMID: 26081042.
Polycystin-1 Is a Cardiomyocyte Mechanosensor That Governs L-Type Ca2+ Channel Protein Stability.Pedrozo Z, Criollo A, Battiprolu PK, Morales CR, Contreras-Ferrat A, Fernández C, Jiang N, Luo X, Caplan MJ, Somlo S, Rothermel BA, Gillette TG, Lavandero S, Hill JA. Circulation. 2015 Jun 16; 2015 Apr 17. PMID: 25888683.
Beyond non-integer Hill coefficients: A novel approach to analyzing binding data, applied to Na+-driven transporters.Ravera S, Quick M, Nicola JP, Carrasco N, Amzel LM. J Gen Physiol. 2015 Jun. PMID: 26009546.
Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy.Ordureau A, Heo JM, Duda DM, Paulo JA, Olszewski JL, Yanishevski D, Rinehart J, Schulman BA, Harper JW. Proc Natl Acad Sci U S A. 2015 May 26; 2015 May 12. PMID: 25969509.
Monitoring brain activity with protein voltage and calcium sensors.Storace DA, Braubach OR, Jin L, Cohen LB, Sung U. Sci Rep. 2015 May 13; 2015 May 13. PMID: 25970202.
Molecular controls of arterial morphogenesis.Simons M, Eichmann A. Circ Res. 2015 May 8. PMID: 25953926.
SubspaceEM: A fast maximum-a-posteriori algorithm for cryo-EM single particle reconstruction.Dvornek NC, Sigworth FJ, Tagare HD. J Struct Biol. 2015 May; 2015 Mar 31. PMID: 25839831.
Slit2 signaling through Robo1 and Robo2 is required for retinal neovascularization.Rama N, Dubrac A, Mathivet T, Ní Chárthaigh RA, Genet G, Cristofaro B, Pibouin-Fragner L, Ma L, Eichmann A, Chédotal A. Nat Med. 2015 May; 2015 Apr 20. PMID: 25894826.
Regulation of glomerulotubular balance. III. Implication of cytosolic calcium in flow-dependent proximal tubule transport.Du Z, Weinbaum S, Weinstein AM, Wang T. Am J Physiol Renal Physiol. 2015 Apr 15; 2015 Jan 28. PMID: 25651568.
Src-family protein tyrosine kinase phosphorylates WNK4 and modulates its inhibitory effect on KCNJ1 (ROMK).Lin DH, Yue P, Yarborough O 3rd, Scholl UI, Giebisch G, Lifton RP, Rinehart J, Wang WH. Proc Natl Acad Sci U S A. 2015 Apr 7; 2015 Mar 24. PMID: 25805816.
The neuronal-specific SGK1.1 (SGK1_v2) kinase as a transcriptional modulator of BAG4, Brox, and PPP1CB genes expression.González-Fernández R, Ávila J, Arteaga MF, Canessa CM, Martín-Vasallo P. Int J Mol Sci. 2015 Apr 2; 2015 Apr 2. PMID: 25849655.
Excess iodide induces an acute inhibition of the sodium/iodide symporter in thyroid male rat cells by increasing reactive oxygen species.Arriagada AA, Albornoz E, Opazo MC, Becerra A, Vidal G, Fardella C, Michea L, Carrasco N, Simon F, Elorza AA, Bueno SM, Kalergis AM, Riedel CA. Endocrinology. 2015 Apr; 2015 Jan 16. PMID: 25594695.
Development of a highly automated and multiplexed targeted proteome pipeline and assay for 112 rat brain synaptic proteins.Colangelo CM, Ivosev G, Chung L, Abbott T, Shifman M, Sakaue F, Cox D, Kitchen RR, Burton L, Tate SA, Gulcicek E, Bonner R, Rinehart J, Nairn AC, Williams KR. Proteomics. 2015 Apr; 2015 Feb 12. PMID: 25476245.
Ghrelin.Müller TD, Nogueiras R, Andermann ML, Andrews ZB, Anker SD, Argente J, Batterham RL, Benoit SC, Bowers CY, Broglio F, Casanueva FF, D'Alessio D, Depoortere I, Geliebter A, Ghigo E, Cole PA, Cowley M, Cummings DE, Dagher A, Diano S, Dickson SL, Diéguez C, Granata R, Grill HJ, Grove K, Habegger KM, Heppner K, Heiman ML, Holsen L, Holst B, Inui A, Jansson JO, Kirchner H, Korbonits M, Laferrère B, LeRoux CW, Lopez M, Morin S, Nakazato M, Nass R, Perez-Tilve D, Pfluger PT, Schwartz TW, Seeley RJ, Sleeman M, Sun Y, Sussel L, Tong J, Thorner MO, van der Lely AJ, van der Ploeg LH, Zigman JM, Kojima M, Kangawa K, Smith RG, Horvath T, Tschöp MH. Mol Metab. 2015 Jun; 2015 Mar 21. PMID: 26042199.
Hypothalamic POMC neurons promote cannabinoid-induced feeding.Koch M, Varela L, Kim JG, Kim JD, Hernández-Nuño F, Simonds SE, Castorena CM, Vianna CR, Elmquist JK, Morozov YM, Rakic P, Bechmann I, Cowley MA, Szigeti-Buck K, Dietrich MO, Gao XB, Diano S, Horvath TL. Nature. 2015 Mar 5; 2015 Feb 18. PMID: 25707796.
Vascular endothelial growth factor receptor 3 controls neural stem cell activation in mice and humans.Han J, Calvo CF, Kang TH, Baker KL, Park JH, Parras C, Levittas M, Birba U, Pibouin-Fragner L, Fragner P, Bilguvar K, Duman RS, Nurmi H, Alitalo K, Eichmann AC, Thomas JL. Cell Rep. 2015 Feb 24; 2015 Feb 19. PMID: 25704818.
In vivo odourant response properties of migrating adult-born neurons in the mouse olfactory bulb.Kovalchuk Y, Homma R, Liang Y, Maslyukov A, Hermes M, Thestrup T, Griesbeck O, Ninkovic J, Cohen LB, Garaschuk O. Nat Commun. 2015 Feb 19; 2015 Feb 19. PMID: 25695931.
Recoded organisms engineered to depend on synthetic amino acids.Rovner AJ, Haimovich AD, Katz SR, Li Z, Grome MW, Gassaway BM, Amiram M, Patel JR, Gallagher RR, Rinehart J, Isaacs FJ. Nature. 2015 Feb 5; 2015 Jan 21. PMID: 25607356.
Neuronal UCP1 expression suggests a mechanism for local thermogenesis during hibernation.Laursen WJ, Mastrotto M, Pesta D, Funk OH, Goodman JB, Merriman DK, Ingolia N, Shulman GI, Bagriantsev SN, Gracheva EO. Proc Natl Acad Sci U S A. 2015 Feb 3; 2015 Jan 20. PMID: 25605929.
Vascular remodeling is governed by a VEGFR3-dependent fluid shear stress set point.Baeyens N, Nicoli S, Coon BG, Ross TD, Van den Dries K, Han J, Lauridsen HM, Mejean CO, Eichmann A, Thomas JL, Humphrey JD, Schwartz MA. Elife. 2015 Feb 2; 2015 Feb 2. PMID: 25643397.
Synaptic localization of neurotransmitter receptors: comparing mechanisms for AMPA and GABAA receptors.Martenson JS, Tomita S. Curr Opin Pharmacol. 2015 Feb; 2014 Dec 17. PMID: 25529200.
YPED: an integrated bioinformatics suite and database for mass spectrometry-based proteomics research.Colangelo CM, Shifman M, Cheung KH, Stone KL, Carriero NJ, Gulcicek EE, Lam TT, Wu T, Bjornson RD, Bruce C, Nairn AC, Rinehart J, Miller PL, Williams KR. Genomics Proteomics Bioinformatics. 2015 Feb; 2015 Feb 21. PMID: 25712262.
Sensory determinants of behavioral dynamics in Drosophila thermotaxis.Klein M, Afonso B, Vonner AJ, Hernandez-Nunez L, Berck M, Tabone CJ, Kane EA, Pieribone VA, Nitabach MN, Cardona A, Zlatic M, Sprecher SG, Gershow M, Garrity PA, Samuel AD. Proc Natl Acad Sci U S A. 2015 Jan 13; 2014 Dec 30. PMID: 25550513.
Revealing the amino acid composition of proteins within an expanded genetic code.Aerni HR, Shifman MA, Rogulina S, O'Donoghue P, Rinehart J. Nucleic Acids Res. 2015 Jan; 2014 Nov 5. PMID: 25378305.

2014

Functionally important carboxyls in a bacterial homologue of the vesicular monoamine transporter (VMAT).Yaffe D, Vergara-Jaque A, Shuster Y, Listov D, Meena S, Singh SK, Forrest LR, Schuldiner S. J Biol Chem. 2014 Dec 5; 2014 Oct 21. PMID: 25336661.
Reducing the genetic code induces massive rearrangement of the proteome.O'Donoghue P, Prat L, Kucklick M, Schäfer JG, Riedel K, Rinehart J, Söll D, Heinemann IU. Proc Natl Acad Sci U S A. 2014 Dec 2; 2014 Nov 17. PMID: 25404328.
Designed phosphoprotein recognition in Escherichia coli.Sawyer N, Gassaway BM, Haimovich AD, Isaacs FJ, Rinehart J, Regan L. ACS Chem Biol. 2014 Nov 21; 2014 Oct 6. PMID: 25272187.
Calcitonin gene-related peptide neurons mediate sleep-specific circadian output in Drosophila.Kunst M, Hughes ME, Raccuglia D, Felix M, Li M, Barnett G, Duah J, Nitabach MN. Curr Biol. 2014 Nov 17; 2014 Oct 30. PMID: 25455031.
Piezo proteins: regulators of mechanosensation and other cellular processes.Bagriantsev SN, Gracheva EO, Gallagher PG. J Biol Chem. 2014 Nov 14; 2014 Oct 10. PMID: 25305018.
Primate phencyclidine model of schizophrenia: sex-specific effects on cognition, brain derived neurotrophic factor, spine synapses, and dopamine turnover in prefrontal cortex.Elsworth JD, Groman SM, Jentsch JD, Leranth C, Redmond DE Jr, Kim JD, Diano S, Roth RH. Int J Neuropsychopharmacol. 2014 Oct 31; 2014 Oct 31. PMID: 25522392.
Neuronal mechanism for acute mechanosensitivity in tactile-foraging waterfowl.Schneider ER, Mastrotto M, Laursen WJ, Schulz VP, Goodman JB, Funk OH, Gallagher PG, Gracheva EO, Bagriantsev SN. Proc Natl Acad Sci U S A. 2014 Oct 14; 2014 Sep 22. PMID: 25246547.
Mitochondrial UCP2 in the central regulation of metabolism.Toda C, Diano S. Best Pract Res Clin Endocrinol Metab. 2014 Oct; 2014 Mar 7. PMID: 25256770.
Big minis from hair cells: mechanism and function.Lv C, Zenisek D. Neuron. 2014 Sep 17. PMID: 25233300.
PTP1b is a physiologic regulator of vascular endothelial growth factor signaling in endothelial cells.Lanahan AA, Lech D, Dubrac A, Zhang J, Zhuang ZW, Eichmann A, Simons M. Circulation. 2014 Sep 9; 2014 Jun 30. PMID: 24982127.
Arterial innervation in development and disease.Eichmann A, Brunet I. Sci Transl Med. 2014 Sep 3. PMID: 25186174.
Endothelial Akt1 mediates angiogenesis by phosphorylating multiple angiogenic substrates.Lee MY, Luciano AK, Ackah E, Rodriguez-Vita J, Bancroft TA, Eichmann A, Simons M, Kyriakides TR, Morales-Ruiz M, Sessa WC. Proc Natl Acad Sci U S A. 2014 Sep 2; 2014 Aug 18. PMID: 25136137.
Hypothalamic prolyl endopeptidase (PREP) regulates pancreatic insulin and glucagon secretion in mice.Kim JD, Toda C, D'Agostino G, Zeiss CJ, DiLeone RJ, Elsworth JD, Kibbey RG, Chan O, Harvey BK, Richie CT, Savolainen M, Myöhänen T, Jeong JK, Diano S. Proc Natl Acad Sci U S A. 2014 Aug 12; 2014 Jul 28. PMID: 25071172.
The H2.0-like homeobox transcription factor modulates yolk sac vascular remodeling in mouse embryos.Prahst C, Kasaai B, Moraes F, Jahnsen ED, Larrivee B, Villegas D, Pardanaud L, Pibouin-Fragner L, Zhang F, Zaun HC, Eichmann A, Jones EA. Arterioscler Thromb Vasc Biol. 2014 Jul; 2014 Apr 24. PMID: 24764455.
Trafficking to the apical and basolateral membranes in polarized epithelial cells.Stoops EH, Caplan MJ. J Am Soc Nephrol. 2014 Jul; 2014 Mar 20. PMID: 24652803.
Leptin signaling in astrocytes regulates hypothalamic neuronal circuits and feeding.Kim JG, Suyama S, Koch M, Jin S, Argente-Arizon P, Argente J, Liu ZW, Zimmer MR, Jeong JK, Szigeti-Buck K, Gao Y, Garcia-Caceres C, Yi CX, Salmaso N, Vaccarino FM, Chowen J, Diano S, Dietrich MO, Tschöp MH, Horvath TL. Nat Neurosci. 2014 Jul; 2014 Jun 1. PMID: 24880214.
Mechanism of cytokinetic contractile ring constriction in fission yeast.Stachowiak MR, Laplante C, Chin HF, Guirao B, Karatekin E, Pollard TD, O'Shaughnessy B. Dev Cell. 2014 Jun 9. PMID: 24914559.
A temperature hypothesis of hypothalamus-driven obesity.Horvath TL, Stachenfeld NS, Diano S. Yale J Biol Med. 2014 Jun; 2014 Jun 6. PMID: 24910560.
Physiological sodium concentrations enhance the iodide affinity of the Na+/I- symporter.Nicola JP, Carrasco N, Amzel LM. Nat Commun. 2014 Jun 3; 2014 Jun 3. PMID: 24888603.
A method for activation of endogenous acid-sensing ion channel 1a (ASIC1a) in the nervous system with high spatial and temporal precision.Li T, Yang Y, Canessa CM. J Biol Chem. 2014 May 30; 2014 Apr 11. PMID: 24727474.
Expanded cellular amino acid pools containing phosphoserine, phosphothreonine, and phosphotyrosine.Steinfeld JB, Aerni HR, Rogulina S, Liu Y, Rinehart J. ACS Chem Biol. 2014 May 16; 2014 Mar 27. PMID: 24646179.
Miniature neurotransmission regulates Drosophila synaptic structural maturation.Choi BJ, Imlach WL, Jiao W, Wolfram V, Wu Y, Grbic M, Cela C, Baines RA, Nitabach MN, McCabe BD. Neuron. 2014 May 7. PMID: 24811381.
Global Ca2+ signaling drives ribbon-independent synaptic transmission at rod bipolar cell synapses.Mehta B, Ke JB, Zhang L, Baden AD, Markowitz AL, Nayak S, Briggman KL, Zenisek D, Singer JH. J Neurosci. 2014 Apr 30. PMID: 24790194.
Kainate receptors mediate signaling in both transient and sustained OFF bipolar cell pathways in mouse retina.Borghuis BG, Looger LL, Tomita S, Demb JB. J Neurosci. 2014 Apr 30. PMID: 24790183.
Vascular biology: Brain vessels squeezed to death.Greif DM, Eichmann A. Nature. 2014 Apr 3; 2014 Mar 26. PMID: 24670635.
Palmitoylethanolamide prevents metabolic alterations and restores leptin sensitivity in ovariectomized rats.Mattace Raso G, Santoro A, Russo R, Simeoli R, Paciello O, Di Carlo C, Diano S, Calignano A, Meli R. Endocrinology. 2014 Apr; 2014 Jan 15. PMID: 24428531.
Auxiliary proteins promote modal gating of AMPA- and kainate-type glutamate receptors.Zhang W, Devi SP, Tomita S, Howe JR. Eur J Neurosci. 2014 Apr. PMID: 24712993.
Postmenopausal hypertension and sodium sensitivity.Kim JM, Kim TH, Lee HH, Lee SH, Wang T. J Menopausal Med. 2014 Apr; 2014 Apr 28. PMID: 25371885.
Polycystin-1 cleavage and the regulation of transcriptional pathways.Merrick D, Bertuccio CA, Chapin HC, Lal M, Chauvet V, Caplan MJ. Pediatr Nephrol. 2014 Apr; 2013 Jul 4. PMID: 23824180.
Molecular motions involved in Na-K-Cl cotransporter-mediated ion transport and transporter activation revealed by internal cross-linking between transmembrane domains 10 and 11/12.Monette MY, Somasekharan S, Forbush B. J Biol Chem. 2014 Mar 14; 2014 Jan 22. PMID: 24451383.
A tarantula-venom peptide antagonizes the TRPA1 nociceptor ion channel by binding to the S1-S4 gating domain.Gui J, Liu B, Cao G, Lipchik AM, Perez M, Dekan Z, Mobli M, Daly NL, Alewood PF, Parker LL, King GF, Zhou Y, Jordt SE, Nitabach MN. Curr Biol. 2014 Mar 3; 2014 Feb 13. PMID: 24530065.
Automatic cryo-EM particle selection for membrane proteins in spherical liposomes.Liu Y, Sigworth FJ. J Struct Biol. 2014 Mar; 2014 Jan 24. PMID: 24468290.
The Na+/I- symporter (NIS): mechanism and medical impact.Portulano C, Paroder-Belenitsky M, Carrasco N. Endocr Rev. 2014 Feb; 2013 Dec 4. PMID: 24311738.
Radioligand binding to nanodisc-reconstituted membrane transporters assessed by the scintillation proximity assay.Nasr ML, Singh SK. Biochemistry. 2014 Jan 14; 2013 Dec 30. PMID: 24344975.
Prolyl carboxypeptidase mRNA expression in the mouse brain.Jeong JK, Diano S. Brain Res. 2014 Jan 13; 2013 Oct 24. PMID: 24161824.
Quantifying the local resolution of cryo-EM density maps.Kucukelbir A, Sigworth FJ, Tagare HD. Nat Methods. 2014 Jan; 2013 Nov 10. PMID: 24213166.

2013

Activation of the Ca²+-sensing receptor induces deposition of tight junction components to the epithelial cell plasma membrane.Jouret F, Wu J, Hull M, Rajendran V, Mayr B, Schöfl C, Geibel J, Caplan MJ. J Cell Sci. 2013 Nov 15; 2013 Sep 6. PMID: 24013548.
Mineralocorticoid receptor phosphorylation regulates ligand binding and renal response to volume depletion and hyperkalemia.Shibata S, Rinehart J, Zhang J, Moeckel G, Castañeda-Bueno M, Stiegler AL, Boggon TJ, Gamba G, Lifton RP. Cell Metab. 2013 Nov 5. PMID: 24206662.
Need glucose to sprout: local metabolic control of angiogenesis.Eichmann A, Simons M. EMBO Mol Med. 2013 Oct; 2013 Aug 27. PMID: 23982994.
Endothelial signaling and the molecular basis of arteriovenous malformation.Atri D, Larrivée B, Eichmann A, Simons M. Cell Mol Life Sci. 2013 Sep 28; 2013 Sep 28. PMID: 24077895.
Genetically targeted optical electrophysiology in intact neural circuits.Cao G, Platisa J, Pieribone VA, Raccuglia D, Kunst M, Nitabach MN. Cell. 2013 Aug 15; 2013 Aug 8. PMID: 23932121.
Physiology. Lymphatics are in my veins.Simons M, Eichmann A. Science. 2013 Aug 9. PMID: 23929973.
Prolyl endopeptidase-deficient mice have reduced synaptic spine density in the CA1 region of the hippocampus, impaired LTP, and spatial learning and memory.D'Agostino G, Kim JD, Liu ZW, Jeong JK, Suyama S, Calignano A, Gao XB, Schwartz M, Diano S. Cereb Cortex. 2013 Aug; 2012 Jul 5. PMID: 22767632.
Noise models and cryo-EM drift correction with a direct-electron camera.Shigematsu H, Sigworth FJ. Ultramicroscopy. 2013 Aug; 2013 Apr 18. PMID: 23748163.
PI(4,5)P(2)-dependent and Ca(2+)-regulated ER-PM interactions mediated by the extended synaptotagmins.Giordano F, Saheki Y, Idevall-Hagren O, Colombo SF, Pirruccello M, Milosevic I, Gracheva EO, Bagriantsev SN, Borgese N, De Camilli P. Cell. 2013 Jun 20. PMID: 23791178.
Homeostatic control of synaptic transmission by distinct glutamate receptors.Yan D, Yamasaki M, Straub C, Watanabe M, Tomita S. Neuron. 2013 May 22. PMID: 23719165.
Epithelial morphogenesis of MDCK cells in three-dimensional collagen culture is modulated by interleukin-8.Wells EK, Yarborough O 3rd, Lifton RP, Cantley LG, Caplan MJ. Am J Physiol Cell Physiol. 2013 May 15; 2013 Mar 13. PMID: 23485708.
Endothelial RAF1/ERK activation regulates arterial morphogenesis.Deng Y, Larrivée B, Zhuang ZW, Atri D, Moraes F, Prahst C, Eichmann A, Simons M. Blood. 2013 May 9; 2013 Mar 25. PMID: 23529931.
Amperometric resolution of a prespike stammer and evoked phases of fast release from retinal bipolar cells.Grabner CP, Zenisek D. J Neurosci. 2013 May 8. PMID: 23658155.
Interactions between VEGFR and Notch signaling pathways in endothelial and neural cells.Thomas JL, Baker K, Han J, Calvo C, Nurmi H, Eichmann AC, Alitalo K. Cell Mol Life Sci. 2013 May; 2013 Mar 12. PMID: 23479133.
The power of VEGF (vascular endothelial growth factor) family molecules.Thomas JL, Eichmann A. Cell Mol Life Sci. 2013 May; 2013 Mar 12. PMID: 23475064.
Coordination of K+ transporters in neurospora: TRK1 is scarce and constitutive, while HAK1 is abundant and highly regulated.Rivetta A, Allen KE, Slayman CW, Slayman CL. Eukaryot Cell. 2013 May; 2013 Mar 8. PMID: 23475706.
Membrane-tethered ligands: tools for cell-autonomous pharmacological manipulation of biological circuits.Choi C, Nitabach MN. Physiology (Bethesda). 2013 May. PMID: 23636262.
Role of reactive oxygen species in hypothalamic regulation of energy metabolism.Diano S. Endocrinol Metab (Seoul). 2013 Mar. PMID: 24396642.
Endothelial ERK signaling controls lymphatic fate specification.Deng Y, Atri D, Eichmann A, Simons M. J Clin Invest. 2013 Mar; 2013 Feb 8. PMID: 23391722.
Synaptic ribbons influence the size and frequency of miniature-like evoked postsynaptic currents.Mehta B, Snellman J, Chen S, Li W, Zenisek D. Neuron. 2013 Feb 6. PMID: 23395377.
O-GlcNAc signaling entrains the circadian clock by inhibiting BMAL1/CLOCK ubiquitination.Li MD, Ruan HB, Hughes ME, Lee JS, Singh JP, Jones SP, Nitabach MN, Yang X. Cell Metab. 2013 Feb 5. PMID: 23395176.
Noise analysis and performance comparison of low current measurement systems for biomedical applications.Dongsoo Kim, Goldstein B, Wei Tang, Sigworth FJ, Culurciello E. IEEE Trans Biomed Circuits Syst. 2013 Feb. PMID: 23853279.
Prolyl carboxypeptidase and its inhibitors in metabolism.Jeong JK, Diano S. Trends Endocrinol Metab. 2013 Feb; 2012 Dec 12. PMID: 23245768.
Molecular parallels between neural and vascular development.Eichmann A, Thomas JL. Cold Spring Harb Perspect Med. 2013 Jan 1; 2013 Jan 1. PMID: 23024177.

2012

Carbon source-dependent expansion of the genetic code in bacteria.Prat L, Heinemann IU, Aerni HR, Rinehart J, O'Donoghue P, Söll D. Proc Natl Acad Sci U S A. 2012 Dec 18; 2012 Nov 26. PMID: 23185002.
Protein aggregation caused by aminoglycoside action is prevented by a hydrogen peroxide scavenger.Ling J, Cho C, Guo LT, Aerni HR, Rinehart J, Söll D. Mol Cell. 2012 Dec 14; 2012 Oct 30. PMID: 23122414.
Regulation of glomerulotubular balance: II: impact of angiotensin II on flow-dependent transport.Du Z, Wan L, Yan Q, Weinbaum S, Weinstein AM, Wang T. Am J Physiol Renal Physiol. 2012 Dec 1; 2012 Sep 5. PMID: 22952281.
Endothelial nuclear factor-κB-dependent regulation of arteriogenesis and branching.Tirziu D, Jaba IM, Yu P, Larrivée B, Coon BG, Cristofaro B, Zhuang ZW, Lanahan AA, Schwartz MA, Eichmann A, Simons M. Circulation. 2012 Nov 27; 2012 Oct 22. PMID: 23091063.
Impact of recovery from desensitization on acid-sensing ion channel-1a (ASIC1a) current and response to high frequency stimulation.Li T, Yang Y, Canessa CM. J Biol Chem. 2012 Nov 23; 2012 Oct 9. PMID: 23048040.
Expression, purification and functional reconstitution of slack sodium-activated potassium channels.Yan Y, Yang Y, Bian S, Sigworth FJ. J Membr Biol. 2012 Nov; 2012 Jun 23. PMID: 22729647.
Enhanced phosphoserine insertion during Escherichia coli protein synthesis via partial UAG codon reassignment and release factor 1 deletion.Heinemann IU, Rovner AJ, Aerni HR, Rogulina S, Cheng L, Olds W, Fischer JT, Söll D, Isaacs FJ, Rinehart J. FEBS Lett. 2012 Oct 19; 2012 Sep 13. PMID: 22982858.
VIP17/MAL expression modulates epithelial cyst formation and ciliogenesis.Takiar V, Mistry K, Carmosino M, Schaeren-Wiemers N, Caplan MJ. Am J Physiol Cell Physiol. 2012 Oct 15; 2012 Aug 15. PMID: 22895261.
Hydration-layer models for cryo-EM image simulation.Shang Z, Sigworth FJ. J Struct Biol. 2012 Oct; 2012 May 17. PMID: 22609687.
Fatty acid amide hydrolase ablation promotes ectopic lipid storage and insulin resistance due to centrally mediated hypothyroidism.Brown WH, Gillum MP, Lee HY, Camporez JP, Zhang XM, Jeong JK, Alves TC, Erion DM, Guigni BA, Kahn M, Samuel VT, Cravatt BF, Diano S, Shulman GI. Proc Natl Acad Sci U S A. 2012 Sep 11; 2012 Aug 21. PMID: 22912404.
Single action potentials and subthreshold electrical events imaged in neurons with a fluorescent protein voltage probe.Jin L, Han Z, Platisa J, Wooltorton JR, Cohen LB, Pieribone VA. Neuron. 2012 Sep 6. PMID: 22958819.
Autoreceptor control of peptide/neurotransmitter corelease from PDF neurons determines allocation of circadian activity in drosophila.Choi C, Cao G, Tanenhaus AK, McCarthy EV, Jung M, Schleyer W, Shang Y, Rosbash M, Yin JC, Nitabach MN. Cell Rep. 2012 Aug 30; 2012 Aug 2. PMID: 22938867.
Context-dependent proangiogenic function of bone morphogenetic protein signaling is mediated by disabled homolog 2.Kim JD, Kang H, Larrivée B, Lee MY, Mettlen M, Schmid SL, Roman BL, Qyang Y, Eichmann A, Jin SW. Dev Cell. 2012 Aug 14. PMID: 22898784.
Regulation of glomerulotubular balance. I. Impact of dopamine on flow-dependent transport.Du Z, Yan Q, Wan L, Weinbaum S, Weinstein AM, Wang T. Am J Physiol Renal Physiol. 2012 Aug 1; 2012 May 2. PMID: 22552936.
High-resolution optical imaging of zebrafish larval ribbon synapse protein RIBEYE, RIM2, and CaV 1.4 by stimulation emission depletion microscopy.Lv C, Gould TJ, Bewersdorf J, Zenisek D. Microsc Microanal. 2012 Aug; 2012 Jul 26. PMID: 22832038.
Deep sequencing the circadian and diurnal transcriptome of Drosophila brain.Hughes ME, Grant GR, Paquin C, Qian J, Nitabach MN. Genome Res. 2012 Jul; 2012 Apr 3. PMID: 22472103.
A Bayesian adaptive basis algorithm for single particle reconstruction.Kucukelbir A, Sigworth FJ, Tagare HD. J Struct Biol. 2012 Jul; 2012 May 1. PMID: 22564910.
Deletion of prolyl carboxypeptidase attenuates the metabolic effects of diet-induced obesity.Jeong JK, Szabo G, Raso GM, Meli R, Diano S. Am J Physiol Endocrinol Metab. 2012 Jun 15; 2012 Mar 27. PMID: 22454290.
The regulation of glutamate receptor trafficking and function by TARPs and other transmembrane auxiliary subunits.Straub C, Tomita S. Curr Opin Neurobiol. 2012 Jun; 2011 Oct 10. PMID: 21993243.
Loop diuretic and ion-binding residues revealed by scanning mutagenesis of transmembrane helix 3 (TM3) of Na-K-Cl cotransporter (NKCC1).Somasekharan S, Tanis J, Forbush B. J Biol Chem. 2012 May 18; 2012 Mar 21. PMID: 22437837.
Neto1 and Neto2: auxiliary subunits that determine key properties of native kainate receptors.Tomita S, Castillo PE. J Physiol. 2012 May 15; 2012 Mar 19. PMID: 22431337.
Susceptibility to a parkinsonian toxin varies during primate development.Morrow BA, Roth RH, Redmond DE Jr, Diano S, Elsworth JD. Exp Neurol. 2012 May; 2012 Feb 14. PMID: 22366325.
Fusion of single proteoliposomes with planar, cushioned bilayers in microfluidic flow cells.Karatekin E, Rothman JE. Nat Protoc. 2012 Apr 19; 2012 Apr 19. PMID: 22517259.
VEGF signaling inside vascular endothelial cells and beyond.Eichmann A, Simons M. Curr Opin Cell Biol. 2012 Apr; 2012 Feb 25. PMID: 22366328.
ALK1 signaling inhibits angiogenesis by cooperating with the Notch pathway.Larrivée B, Prahst C, Gordon E, del Toro R, Mathivet T, Duarte A, Simons M, Eichmann A. Dev Cell. 2012 Mar 13. PMID: 22421041.
Circadian expression of clock genes in mouse macrophages, dendritic cells, and B cells.Silver AC, Arjona A, Hughes ME, Nitabach MN, Fikrig E. Brain Behav Immun. 2012 Mar; 2011 Oct 13. PMID: 22019350.
Renal outer medullary potassium channel knockout models reveal thick ascending limb function and dysfunction.Wang T. Clin Exp Nephrol. 2012 Feb; 2011 Nov 1. PMID: 22038261.
Prolyl carboxypeptidase regulates energy expenditure and the thyroid axis.Jeong JK, Szabo G, Kelly K, Diano S. Endocrinology. 2012 Feb; 2011 Dec 27. PMID: 22202165.
The γ-secretase cleavage product of polycystin-1 regulates TCF and CHOP-mediated transcriptional activation through a p300-dependent mechanism.Merrick D, Chapin H, Baggs JE, Yu Z, Somlo S, Sun Z, Hogenesch JB, Caplan MJ. Dev Cell. 2012 Jan 17; 2011 Dec 15. PMID: 22178500.
Regulatory activation is accompanied by movement in the C terminus of the Na-K-Cl cotransporter (NKCC1).Monette MY, Forbush B. J Biol Chem. 2012 Jan 13; 2011 Nov 25. PMID: 22121194.
Defined criteria for auxiliary subunits of glutamate receptors.Yan D, Tomita S. J Physiol. 2012 Jan 1; 2011 Sep 26. PMID: 21946847.
Mitochondrial uncoupling protein 2 (UCP2) in glucose and lipid metabolism.Diano S, Horvath TL. Trends Mol Med. 2012 Jan; 2011 Sep 12. PMID: 21917523.

2011

Minimal transition state charge stabilization of the oxyanion during peptide bond formation by the ribosome.Carrasco N, Hiller DA, Strobel SA. Biochemistry. 2011 Dec 6; 2011 Nov 9. PMID: 22035282.
Preactivation of AMPK by metformin may ameliorate the epithelial cell damage caused by renal ischemia.Seo-Mayer PW, Thulin G, Zhang L, Alves DS, Ardito T, Kashgarian M, Caplan MJ. Am J Physiol Renal Physiol. 2011 Dec; 2011 Aug 17. PMID: 21849490.
PDZ binding of TARPγ-8 controls synaptic transmission but not synaptic plasticity.Sumioka A, Brown TE, Kato AS, Bredt DS, Kauer JA, Tomita S. Nat Neurosci. 2011 Oct 16; 2011 Oct 16. PMID: 22002768.
Head-mountable high speed camera for optical neural recording.Park JH, Platisa J, Verhagen JV, Gautam SH, Osman A, Kim D, Pieribone VA, Culurciello E. J Neurosci Methods. 2011 Oct 15; 2011 Jul 6. PMID: 21763348.
Polycystic kidney disease: pathogenesis and potential therapies.Takiar V, Caplan MJ. Biochim Biophys Acta. 2011 Oct; 2010 Dec 10. PMID: 21146605.
Macrophages promote cyst growth in polycystic kidney disease.Karihaloo A, Koraishy F, Huen SC, Lee Y, Merrick D, Caplan MJ, Somlo S, Cantley LG. J Am Soc Nephrol. 2011 Oct; 2011 Sep 15. PMID: 21921140.
Peroxisome proliferation-associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity.Diano S, Liu ZW, Jeong JK, Dietrich MO, Ruan HB, Kim E, Suyama S, Kelly K, Gyengesi E, Arbiser JL, Belsham DD, Sarruf DA, Schwartz MW, Bennett AM, Shanabrough M, Mobbs CV, Yang X, Gao XB, Horvath TL. Nat Med. 2011 Aug 28; 2011 Aug 28. PMID: 21873987.
WNK2 kinase is a novel regulator of essential neuronal cation-chloride cotransporters.Rinehart J, Vázquez N, Kahle KT, Hodson CA, Ring AM, Gulcicek EE, Louvi A, Bobadilla NA, Gamba G, Lifton RP. J Biol Chem. 2011 Aug 26; 2011 Jul 6. PMID: 21733846.
Expanding the genetic code of Escherichia coli with phosphoserine.Park HS, Hohn MJ, Umehara T, Guo LT, Osborne EM, Benner J, Noren CJ, Rinehart J, Söll D. Science. 2011 Aug 26. PMID: 21868676.
Development of new peptide-based tools for studying synaptic ribbon function.Francis AA, Mehta B, Zenisek D. J Neurophysiol. 2011 Aug; 2011 Jun 8. PMID: 21653726.
Acute destruction of the synaptic ribbon reveals a role for the ribbon in vesicle priming.Snellman J, Mehta B, Babai N, Bartoletti TM, Akmentin W, Francis A, Matthews G, Thoreson W, Zenisek D. Nat Neurosci. 2011 Jul 24; 2011 Jul 24. PMID: 21785435.
Outlines of the pore in open and closed conformations describe the gating mechanism of ASIC1.Li T, Yang Y, Canessa CM. Nat Commun. 2011 Jul 19; 2011 Jul 19. PMID: 21772270.
An instructive role for patterned spontaneous retinal activity in mouse visual map development.Xu HP, Furman M, Mineur YS, Chen H, King SL, Zenisek D, Zhou ZJ, Butts DA, Tian N, Picciotto MR, Crair MC. Neuron. 2011 Jun 23. PMID: 21689598.
Nicotine decreases food intake through activation of POMC neurons.Mineur YS, Abizaid A, Rao Y, Salas R, DiLeone RJ, Gündisch D, Diano S, De Biasi M, Horvath TL, Gao XB, Picciotto MR. Science. 2011 Jun 10. PMID: 21659607.
Synchronized bilateral synaptic inputs to Drosophila melanogaster neuropeptidergic rest/arousal neurons.McCarthy EV, Wu Y, Decarvalho T, Brandt C, Cao G, Nitabach MN. J Neurosci. 2011 Jun 1. PMID: 21632940.
Distinct functions of kainate receptors in the brain are determined by the auxiliary subunit Neto1.Straub C, Hunt DL, Yamasaki M, Kim KS, Watanabe M, Castillo PE, Tomita S. Nat Neurosci. 2011 May 29; 2011 May 29. PMID: 21623363.
AMP-activated protein kinase (AMPK) activation and glycogen synthase kinase-3β (GSK-3β) inhibition induce Ca2+-independent deposition of tight junction components at the plasma membrane.Zhang L, Jouret F, Rinehart J, Sfakianos J, Mellman I, Lifton RP, Young LH, Caplan MJ. J Biol Chem. 2011 May 13; 2011 Mar 7. PMID: 21383016.
Rare mutations in the human Na-K-Cl cotransporter (NKCC2) associated with lower blood pressure exhibit impaired processing and transport function.Monette MY, Rinehart J, Lifton RP, Forbush B. Am J Physiol Renal Physiol. 2011 Apr; 2011 Jan 5. PMID: 21209010.
Asp433 in the closing gate of ASIC1 determines stability of the open state without changing properties of the selectivity filter or Ca2+ block.Li T, Yang Y, Canessa CM. J Gen Physiol. 2011 Mar. PMID: 21357733.
Activating AMP-activated protein kinase (AMPK) slows renal cystogenesis.Takiar V, Nishio S, Seo-Mayer P, King JD Jr, Li H, Zhang L, Karihaloo A, Hallows KR, Somlo S, Caplan MJ. Proc Natl Acad Sci U S A. 2011 Feb 8; 2011 Jan 24. PMID: 21262823.
Drosophila glia use a conserved cotransporter mechanism to regulate extracellular volume.Leiserson WM, Forbush B, Keshishian H. Glia. 2011 Feb. PMID: 21125654.
New aspects of melanocortin signaling: a role for PRCP in α-MSH degradation.Diano S. Front Neuroendocrinol. 2011 Jan; 2010 Oct 25. PMID: 20932857.

2010

Shear stress-induced changes of membrane transporter localization and expression in mouse proximal tubule cells.Duan Y, Weinstein AM, Weinbaum S, Wang T. Proc Natl Acad Sci U S A. 2010 Dec 14; 2010 Nov 24. PMID: 21106755.
Identification and regulation of reticulon 4B (Nogo-B) in renal tubular epithelial cells.Marin EP, Moeckel G, Al-Lamki R, Bradley J, Yan Q, Wang T, Wright PL, Yu J, Sessa WC. Am J Pathol. 2010 Dec; 2010 Oct 22. PMID: 20971739.
Improved hidden Markov models for molecular motors, part 1: basic theory.Müllner FE, Syed S, Selvin PR, Sigworth FJ. Biophys J. 2010 Dec 1. PMID: 21112293.
Alpha-melanocyte stimulating hormone: production and degradation.D'Agostino G, Diano S. J Mol Med (Berl). 2010 Dec; 2010 Jul 10. PMID: 20617297.
Polycystin-1 surface localization is stimulated by polycystin-2 and cleavage at the G protein-coupled receptor proteolytic site.Chapin HC, Rajendran V, Caplan MJ. Mol Biol Cell. 2010 Dec; 2010 Oct 27. PMID: 20980620.
AS160 associates with the Na+,K+-ATPase and mediates the adenosine monophosphate-stimulated protein kinase-dependent regulation of sodium pump surface expression.Alves DS, Farr GA, Seo-Mayer P, Caplan MJ. Mol Biol Cell. 2010 Dec; 2010 Oct 13. PMID: 20943949.
The cell biology of polycystic kidney disease.Chapin HC, Caplan MJ. J Cell Biol. 2010 Nov 15. PMID: 21079243.
MAL/VIP17, a new player in the regulation of NKCC2 in the kidney.Carmosino M, Rizzo F, Procino G, Basco D, Valenti G, Forbush B, Schaeren-Wiemers N, Caplan MJ, Svelto M. Mol Biol Cell. 2010 Nov 15; 2010 Sep 22. PMID: 20861303.
Corticosterone regulates synaptic input organization of POMC and NPY/AgRP neurons in adult mice.Gyengesi E, Liu ZW, D'Agostino G, Gan G, Horvath TL, Gao XB, Diano S. Endocrinology. 2010 Nov; 2010 Sep 15. PMID: 20843996.
Association with {beta}-COP regulates the trafficking of the newly synthesized Na,K-ATPase.Morton MJ, Farr GA, Hull M, Capendeguy O, Horisberger JD, Caplan MJ. J Biol Chem. 2010 Oct 29; 2010 Aug 26. PMID: 20801885.
Patch-clamp amplifiers on a chip.Weerakoon P, Culurciello E, Yang Y, Santos-Sacchi J, Kindlmann PJ, Sigworth FJ. J Neurosci Methods. 2010 Oct 15; 2010 Jul 15. PMID: 20637803.
Asn415 in the beta11-beta12 linker decreases proton-dependent desensitization of ASIC1.Li T, Yang Y, Canessa CM. J Biol Chem. 2010 Oct 8; 2010 Jul 30. PMID: 20675379.
Exosome release of β-catenin: a novel mechanism that antagonizes Wnt signaling.Chairoungdua A, Smith DL, Pochard P, Hull M, Caplan MJ. J Cell Biol. 2010 Sep 20; 2010 Sep 13. PMID: 20837771.
TLR9-targeted biodegradable nanoparticles as immunization vectors protect against West Nile encephalitis.Demento SL, Bonafé N, Cui W, Kaech SM, Caplan MJ, Fikrig E, Ledizet M, Fahmy TM. J Immunol. 2010 Sep 1; 2010 Jul 26. PMID: 20660705.
Agrp neurons mediate Sirt1's action on the melanocortin system and energy balance: roles for Sirt1 in neuronal firing and synaptic plasticity.Dietrich MO, Antunes C, Geliang G, Liu ZW, Borok E, Nie Y, Xu AW, Souza DO, Gao Q, Diano S, Gao XB, Horvath TL. J Neurosci. 2010 Sep 1. PMID: 20810901.
An adaptive Expectation-Maximization algorithm with GPU implementation for electron cryomicroscopy.Tagare HD, Barthel A, Sigworth FJ. J Struct Biol. 2010 Sep; 2010 Jun 9. PMID: 20538058.
Synaptic input organization of the melanocortin system predicts diet-induced hypothalamic reactive gliosis and obesity.Horvath TL, Sarman B, García-Cáceres C, Enriori PJ, Sotonyi P, Shanabrough M, Borok E, Argente J, Chowen JA, Perez-Tilve D, Pfluger PT, Brönneke HS, Levin BE, Diano S, Cowley MA, Tschöp MH. Proc Natl Acad Sci U S A. 2010 Aug 17; 2010 Aug 2. PMID: 20679202.
Cloning and identification of tissue-specific expression of KCNN4 splice variants in rat colon.Barmeyer C, Rahner C, Yang Y, Sigworth FJ, Binder HJ, Rajendran VM. Am J Physiol Cell Physiol. 2010 Aug; 2010 May 5. PMID: 20445171.
Leu85 in the beta1-beta2 linker of ASIC1 slows activation and decreases the apparent proton affinity by stabilizing a closed conformation.Li T, Yang Y, Canessa CM. J Biol Chem. 2010 Jul 16; 2010 May 17. PMID: 20479002.
Two residues in the extracellular domain convert a nonfunctional ASIC1 into a proton-activated channel.Li T, Yang Y, Canessa CM. Am J Physiol Cell Physiol. 2010 Jul; 2010 Apr 28. PMID: 20427715.
Fragile X mental retardation protein controls gating of the sodium-activated potassium channel Slack.Brown MR, Kronengold J, Gazula VR, Chen Y, Strumbos JG, Sigworth FJ, Navaratnam D, Kaczmarek LK. Nat Neurosci. 2010 Jul; 2010 May 30. PMID: 20512134.
A sympathetic view on free radicals in diabetes.Diano S, Horvath TL. Neuron. 2010 Jun 24. PMID: 20620864.
TARP phosphorylation regulates synaptic AMPA receptors through lipid bilayers.Sumioka A, Yan D, Tomita S. Neuron. 2010 Jun 10. PMID: 20547132.
Reference Free Structure Determination through Eigenvectors of Center of Mass Operators.Coifman RR, Shkolnisky Y, Sigworth FJ, Singer A. Appl Comput Harmon Anal. 2010 May. PMID: 20436952.
Determinants of erythrocyte hydration.Rinehart J, Gulcicek EE, Joiner CH, Lifton RP, Gallagher PG. Curr Opin Hematol. 2010 May. PMID: 20182354.
Phosphorylation state of the Na+-K+-Cl- cotransporter (NKCC1) in the gills of Atlantic killifish (Fundulus heteroclitus) during acclimation to water of varying salinity.Flemmer AW, Monette MY, Djurisic M, Dowd B, Darman R, Gimenez I, Forbush B. J Exp Biol. 2010 May. PMID: 20400641.
Real-time visualization of complexin during single exocytic events.An SJ, Grabner CP, Zenisek D. Nat Neurosci. 2010 May; 2010 Apr 11. PMID: 20383135.
Circadian biology: environmental regulation of a multi-oscillator network.Choi C, Nitabach MN. Curr Biol. 2010 Apr 13. PMID: 20392424.
A new bright green-emitting fluorescent protein--engineered monomeric and dimeric forms.Ilagan RP, Rhoades E, Gruber DF, Kao HT, Pieribone VA, Regan L. FEBS J. 2010 Apr; 2010 Mar 18. PMID: 20345907.
Ligand-modified gene carriers increased uptake in target cells but reduced DNA release and transfection efficiency.Cu Y, LeMoëllic C, Caplan MJ, Saltzman WM. Nanomedicine. 2010 Apr; 2009 Oct 2. PMID: 19800989.
Mouse cystic fibrosis transmembrane conductance regulator forms cAMP-PKA-regulated apical chloride channels in cortical collecting duct.Lu M, Dong K, Egan ME, Giebisch GH, Boulpaep EL, Hebert SC. Proc Natl Acad Sci U S A. 2010 Mar 30; 2010 Mar 15. PMID: 20231442.
Altered renal proximal tubular endocytosis and histology in mice lacking myosin-VI.Gotoh N, Yan Q, Du Z, Biemesderfer D, Kashgarian M, Mooseker MS, Wang T. Cytoskeleton (Hoboken). 2010 Mar. PMID: 20175219.
A fast, single-vesicle fusion assay mimics physiological SNARE requirements.Karatekin E, Di Giovanni J, Iborra C, Coleman J, O'Shaughnessy B, Seagar M, Rothman JE. Proc Natl Acad Sci U S A. 2010 Feb 23; 2010 Feb 2. PMID: 20133592.
Partial correction of cystic fibrosis defects with PLGA nanoparticles encapsulating curcumin.Cartiera MS, Ferreira EC, Caputo C, Egan ME, Caplan MJ, Saltzman WM. Mol Pharm. 2010 Feb 1. PMID: 19886674.
Regulation of ionotropic glutamate receptors by their auxiliary subunits.Tomita S. Physiology (Bethesda). 2010 Feb. PMID: 20134027.
Assembly and stoichiometry of the AMPA receptor and transmembrane AMPA receptor regulatory protein complex.Kim KS, Yan D, Tomita S. J Neurosci. 2010 Jan 20. PMID: 20089915.

2009

Wide-field and two-photon imaging of brain activity with voltage- and calcium-sensitive dyes.Homma R, Baker BJ, Jin L, Garaschuk O, Konnerth A, Cohen LB, Zecevic D. Philos Trans R Soc Lond B Biol Sci. 2009 Sep 12. PMID: 19651647.
Structure of the BK potassium channel in a lipid membrane from electron cryomicroscopy.Wang L, Sigworth FJ. Nature. 2009 Sep 10; 2009 Aug 30. PMID: 19718020.
The potassium chloride cotransporter KCC-2 coordinates development of inhibitory neurotransmission and synapse structure in Caenorhabditis elegans.Tanis JE, Bellemer A, Moresco JJ, Forbush B, Koelle MR. J Neurosci. 2009 Aug 12. PMID: 19675228.
Sites of regulated phosphorylation that control K-Cl cotransporter activity.Rinehart J, Maksimova YD, Tanis JE, Stone KL, Hodson CA, Zhang J, Risinger M, Pan W, Wu D, Colangelo CM, Forbush B, Joiner CH, Gulcicek EE, Gallagher PG, Lifton RP. Cell. 2009 Aug 7. PMID: 19665974.
Prolylcarboxypeptidase regulates food intake by inactivating alpha-MSH in rodents.Wallingford N, Perroud B, Gao Q, Coppola A, Gyengesi E, Liu ZW, Gao XB, Diament A, Haus KA, Shariat-Madar Z, Mahdi F, Wardlaw SL, Schmaier AH, Warden CH, Diano S. J Clin Invest. 2009 Aug; 2009 Jul 20. PMID: 19620781.
Cellular dissection of circadian peptide signals with genetically encoded membrane-tethered ligands.Choi C, Fortin JP, McCarthy Ev, Oksman L, Kopin AS, Nitabach MN. Curr Biol. 2009 Jul 28; 2009 Jul 9. PMID: 19592252.
Membrane proteins follow multiple pathways to the basolateral cell surface in polarized epithelial cells.Farr GA, Hull M, Mellman I, Caplan MJ. J Cell Biol. 2009 Jul 27; 2009 Jul 20. PMID: 19620635.
Imaging exocytosis in retinal bipolar cells with TIRF microscopy.Joselevitch C, Zenisek D. J Vis Exp. 2009 Jun 9; 2009 Jun 9. PMID: 19513018.
Switching between transient and sustained signalling at the rod bipolar-AII amacrine cell synapse of the mouse retina.Snellman J, Zenisek D, Nawy S. J Physiol. 2009 Jun 1; 2009 Mar 30. PMID: 19332496.
Inflammasome-activating nanoparticles as modular systems for optimizing vaccine efficacy.Demento SL, Eisenbarth SC, Foellmer HG, Platt C, Caplan MJ, Mark Saltzman W, Mellman I, Ledizet M, Fikrig E, Flavell RA, Fahmy TM. Vaccine. 2009 May 18; 2009 Apr 3. PMID: 19428913.
The uptake and intracellular fate of PLGA nanoparticles in epithelial cells.Cartiera MS, Johnson KM, Rajendran V, Caplan MJ, Saltzman WM. Biomaterials. 2009 May; 2009 Feb 20. PMID: 19232712.
Evidence that exocytosis is driven by calcium entry through multiple calcium channels in goldfish retinal bipolar cells.Coggins M, Zenisek D. J Neurophysiol. 2009 May; 2009 Feb 25. PMID: 19244355.
Perceptual stability during dramatic changes in olfactory bulb activation maps and dramatic declines in activation amplitudes.Homma R, Cohen LB, Kosmidis EK, Youngentob SL. Eur J Neurosci. 2009 Mar. PMID: 19291227.
Fuel utilization by hypothalamic neurons: roles for ROS.Horvath TL, Andrews ZB, Diano S. Trends Endocrinol Metab. 2009 Mar; 2008 Dec 10. PMID: 19084428.
Interaction of the aromatics Tyr-72/Trp-288 in the interface of the extracellular and transmembrane domains is essential for proton gating of acid-sensing ion channels.Li T, Yang Y, Canessa CM. J Biol Chem. 2009 Feb 13; 2008 Dec 11. PMID: 19074149.
A transmembrane accessory subunit that modulates kainate-type glutamate receptors.Zhang W, St-Gelais F, Grabner CP, Trinidad JC, Sumioka A, Morimoto-Tomita M, Kim KS, Straub C, Burlingame AL, Howe JR, Tomita S. Neuron. 2009 Feb 12. PMID: 19217376.
Functional expression of the olfactory signaling system in the kidney.Pluznick JL, Zou DJ, Zhang X, Yan Q, Rodriguez-Gil DJ, Eisner C, Wells E, Greer CA, Wang T, Firestein S, Schnermann J, Caplan MJ. Proc Natl Acad Sci U S A. 2009 Feb 10; 2009 Jan 27. PMID: 19174512.
Autoinactivation of neuronal AMPA receptors via glutamate-regulated TARP interaction.Morimoto-Tomita M, Zhang W, Straub C, Cho CH, Kim KS, Howe JR, Tomita S. Neuron. 2009 Jan 15. PMID: 19146816.
Dystroglycan and AMP kinase: polarity's protectors when the power goes out.Zhang L, Seo-Mayer P, Caplan MJ. Dev Cell. 2009 Jan. PMID: 19154710.

2008

Phase coupling of a circadian neuropeptide with rest/activity rhythms detected using a membrane-tethered spider toxin.Wu Y, Cao G, Pavlicek B, Luo X, Nitabach MN. PLoS Biol. 2008 Nov 4. PMID: 18986214.
Streptavidin crystals as nanostructured supports and image-calibration references for cryo-EM data collection.Wang L, Ounjai P, Sigworth FJ. J Struct Biol. 2008 Nov; 2008 Aug 5. PMID: 18707004.
Neutrophil gelatinase-associated lipocalin suppresses cyst growth by Pkd1 null cells in vitro and in vivo.Wei F, Karihaloo A, Yu Z, Marlier A, Seth P, Shibazaki S, Wang T, Sukhatme VP, Somlo S, Cantley LG. Kidney Int. 2008 Nov; 2008 Aug 13. PMID: 18974761.
Polycystin-1 C-terminal tail associates with beta-catenin and inhibits canonical Wnt signaling.Lal M, Song X, Pluznick JL, Di Giovanni V, Merrick DM, Rosenblum ND, Chauvet V, Gottardi CJ, Pei Y, Caplan MJ. Hum Mol Genet. 2008 Oct 15; 2008 Jul 16. PMID: 18632682.
Graph Laplacian tomography from unknown random projections.Coifman RR, Shkolnisky Y, Sigworth FJ, Singer A. IEEE Trans Image Process. 2008 Oct. PMID: 18784036.
Exon loss accounts for differential sorting of Na-K-Cl cotransporters in polarized epithelial cells.Carmosino M, Giménez I, Caplan M, Forbush B. Mol Biol Cell. 2008 Oct; 2008 Jul 30. PMID: 18667527.
Female ROMK null mice manifest more severe Bartter II phenotype on renal function and higher PGE2 production.Yan Q, Yang X, Cantone A, Giebisch G, Hebert S, Wang T. Am J Physiol Regul Integr Comp Physiol. 2008 Sep; 2008 Jun 25. PMID: 18579648.
Epithelial junctions and polarity: complexes and kinases.Caplan MJ, Seo-Mayer P, Zhang L. Curr Opin Nephrol Hypertens. 2008 Sep. PMID: 18695392.
Transition state chirality and role of the vicinal hydroxyl in the ribosomal peptidyl transferase reaction.Huang KS, Carrasco N, Pfund E, Strobel SA. Biochemistry. 2008 Aug 26; 2008 Aug 2. PMID: 18672893.
Shear-induced reorganization of renal proximal tubule cell actin cytoskeleton and apical junctional complexes.Duan Y, Gotoh N, Yan Q, Du Z, Weinstein AM, Wang T, Weinbaum S. Proc Natl Acad Sci U S A. 2008 Aug 12; 2008 Aug 6. PMID: 18685100.
Genetically encoded fluorescent sensors of membrane potential.Baker BJ, Mutoh H, Dimitrov D, Akemann W, Perron A, Iwamoto Y, Jin L, Cohen LB, Isacoff EY, Pieribone VA, Hughes T, Knöpfel T. Brain Cell Biol. 2008 Aug; 2008 Aug 5. PMID: 18679801.
Circadian control of membrane excitability in Drosophila melanogaster lateral ventral clock neurons.Cao G, Nitabach MN. J Neurosci. 2008 Jun 18. PMID: 18562620.
Mouse model of type II Bartter's syndrome. I. Upregulation of thiazide-sensitive Na-Cl cotransport activity.Cantone A, Yang X, Yan Q, Giebisch G, Hebert SC, Wang T. Am J Physiol Renal Physiol. 2008 Jun; 2008 Apr 2. PMID: 18385266.
Simple chordates exhibit a proton-independent function of acid-sensing ion channels.Coric T, Passamaneck YJ, Zhang P, Di Gregorio A, Canessa CM. FASEB J. 2008 Jun; 2008 Jan 22. PMID: 18211956.
Design opportunities for actively targeted nanoparticle vaccines.Fahmy TM, Demento SL, Caplan MJ, Mellman I, Saltzman WM. Nanomedicine (Lond). 2008 Jun. PMID: 18510429.
Circadian rhythms. Integrating circadian timekeeping with cellular physiology.Harrisingh MC, Nitabach MN. Science. 2008 May 16. PMID: 18487177.
Type 3 deiodinase in hypoxia: to cool or to kill?Diano S, Horvath TL. Cell Metab. 2008 May. PMID: 18460327.
Electrical silencing of PDF neurons advances the phase of non-PDF clock neurons in Drosophila.Wu Y, Cao G, Nitabach MN. J Biol Rhythms. 2008 Apr. PMID: 18375861.
Vesicle association and exocytosis at ribbon and extraribbon sites in retinal bipolar cell presynaptic terminals.Zenisek D. Proc Natl Acad Sci U S A. 2008 Mar 25; 2008 Mar 13. PMID: 18339810.
A brain-specific SGK1 splice isoform regulates expression of ASIC1 in neurons.Arteaga MF, Coric T, Straub C, Canessa CM. Proc Natl Acad Sci U S A. 2008 Mar 18; 2008 Mar 11. PMID: 18334630.
Intramolecular and intermolecular fluorescence resonance energy transfer in fluorescent protein-tagged Na-K-Cl cotransporter (NKCC1): sensitivity to regulatory conformational change and cell volume.Pedersen M, Carmosino M, Forbush B. J Biol Chem. 2008 Feb 1; 2007 Nov 28. PMID: 18045874.
Organization of the Drosophila circadian control circuit.Nitabach MN, Taghert PH. Curr Biol. 2008 Jan 22. PMID: 18211849.
Anticonvulsant effects of leptin in epilepsy.Diano S, Horvath TL. J Clin Invest. 2008 Jan. PMID: 18097479.

2007

AMPA receptors and stargazin-like transmembrane AMPA receptor-regulatory proteins mediate hippocampal kainate neurotoxicity.Tomita S, Byrd RK, Rouach N, Bellone C, Venegas A, O'Brien JL, Kim KS, Olsen O, Nicoll RA, Bredt DS. Proc Natl Acad Sci U S A. 2007 Nov 20; 2007 Nov 13. PMID: 18000041.
Intracellular Ca2+ regulates free-running circadian clock oscillation in vivo.Harrisingh MC, Wu Y, Lnenicka GA, Nitabach MN. J Neurosci. 2007 Nov 14. PMID: 18003827.
The last few frames of the voltage-gating movie.Sigworth FJ. Biophys J. 2007 Nov 1; 2007 Aug 17. PMID: 17704178.
Stimulated exocytosis of endosomes in goldfish retinal bipolar neurons.Coggins MR, Grabner CP, Almers W, Zenisek D. J Physiol. 2007 Nov 1; 2007 Sep 6. PMID: 17823206.
Arrestins and spinophilin competitively regulate Na+,K+-ATPase trafficking through association with a large cytoplasmic loop of the Na+,K+-ATPase.Kimura T, Allen PB, Nairn AC, Caplan MJ. Mol Biol Cell. 2007 Nov; 2007 Sep 5. PMID: 17804821.
Importance of the Debye screening length on nanowire field effect transistor sensors.Stern E, Wagner R, Sigworth FJ, Breaker R, Fahmy TM, Reed MA. Nano Lett. 2007 Nov; 2007 Oct 3. PMID: 17914853.
MAL decreases the internalization of the aquaporin-2 water channel.Kamsteeg EJ, Duffield AS, Konings IB, Spencer J, Pagel P, Deen PM, Caplan MJ. Proc Natl Acad Sci U S A. 2007 Oct 16; 2007 Oct 10. PMID: 17940053.
Two conformational states of the membrane-associated Bacillus thuringiensis Cry4Ba delta-endotoxin complex revealed by electron crystallography: implications for toxin-pore formation.Ounjai P, Unger VM, Sigworth FJ, Angsuthanasombat C. Biochem Biophys Res Commun. 2007 Oct 5; 2007 Jul 25. PMID: 17681273.
Two families of TARP isoforms that have distinct effects on the kinetic properties of AMPA receptors and synaptic currents.Cho CH, St-Gelais F, Zhang W, Tomita S, Howe JR. Neuron. 2007 Sep 20. PMID: 17880893.
Transport protein sorting in polarized epithelial cells.Zhang L, Caplan MJ. Sheng Li Xue Bao. 2007 Aug 25. PMID: 17700970.
Holey carbon micro-arrays for transmission electron microscopy: a microcontact printing approach.Chester DW, Klemic JF, Stern E, Sigworth FJ, Klemic KG. Ultramicroscopy. 2007 Aug; 2007 Jan 30. PMID: 17331648.
NHE3 phosphorylation at serines 552 and 605 does not directly affect NHE3 activity.Kocinsky HS, Dynia DW, Wang T, Aronson PS. Am J Physiol Renal Physiol. 2007 Jul; 2007 Apr 4. PMID: 17409282.
Tetraspan proteins: regulators of renal structure and function.Caplan MJ, Kamsteeg EJ, Duffield A. Curr Opin Nephrol Hypertens. 2007 Jul. PMID: 17565278.
The future of the pump.Caplan MJ. J Clin Gastroenterol. 2007 Jul. PMID: 17575526.
Multiple translational isoforms give functional specificity to serum- and glucocorticoid-induced kinase 1.Arteaga MF, Alvarez de la Rosa D, Alvarez JA, Canessa CM. Mol Biol Cell. 2007 Jun; 2007 Mar 21. PMID: 17377066.
Hormonal regulation of the arcuate nucleus melanocortin system.Coppola A, Diano S. Front Biosci. 2007 May 1; 2007 May 1. PMID: 17485318.
Three fluorescent protein voltage sensors exhibit low plasma membrane expression in mammalian cells.Baker BJ, Lee H, Pieribone VA, Cohen LB, Isacoff EY, Knopfel T, Kosmidis EK. J Neurosci Methods. 2007 Mar 30; 2006 Nov 28. PMID: 17126911.
In vivo simultaneous tracing and Ca(2+) imaging of local neuronal circuits.Nagayama S, Zeng S, Xiong W, Fletcher ML, Masurkar AV, Davis DJ, Pieribone VA, Chen WR. Neuron. 2007 Mar 15. PMID: 17359915.
An SGK1 site in WNK4 regulates Na+ channel and K+ channel activity and has implications for aldosterone signaling and K+ homeostasis.Ring AM, Leng Q, Rinehart J, Wilson FH, Kahle KT, Hebert SC, Lifton RP. Proc Natl Acad Sci U S A. 2007 Mar 6; 2007 Feb 22. PMID: 17360471.
WNK4 regulates activity of the epithelial Na+ channel in vitro and in vivo.Ring AM, Cheng SX, Leng Q, Kahle KT, Rinehart J, Lalioti MD, Volkman HM, Wilson FH, Hebert SC, Lifton RP. Proc Natl Acad Sci U S A. 2007 Mar 6; 2007 Feb 26. PMID: 17360470.
The residues determining differences in ion affinities among the alternative splice variants F, A, and B of the mammalian renal Na-K-Cl cotransporter (NKCC2).Giménez I, Forbush B. J Biol Chem. 2007 Mar 2; 2006 Dec 23. PMID: 17186942.
A central thermogenic-like mechanism in feeding regulation: an interplay between arcuate nucleus T3 and UCP2.Coppola A, Liu ZW, Andrews ZB, Paradis E, Roy MC, Friedman JM, Ricquier D, Richard D, Horvath TL, Gao XB, Diano S. Cell Metab. 2007 Jan. PMID: 17189204.
Anorectic estrogen mimics leptin's effect on the rewiring of melanocortin cells and Stat3 signaling in obese animals.Gao Q, Mezei G, Nie Y, Rao Y, Choi CS, Bechmann I, Leranth C, Toran-Allerand D, Priest CA, Roberts JL, Gao XB, Mobbs C, Shulman GI, Diano S, Horvath TL. Nat Med. 2007 Jan; 2006 Dec 31. PMID: 17195839.

2006

Using cryo-EM to measure the dipole potential of a lipid membrane.Wang L, Bose PS, Sigworth FJ. Proc Natl Acad Sci U S A. 2006 Dec 5; 2006 Nov 20. PMID: 17116859.
AMP-activated protein kinase regulates the assembly of epithelial tight junctions.Zhang L, Li J, Young LH, Caplan MJ. Proc Natl Acad Sci U S A. 2006 Nov 14; 2006 Nov 6. PMID: 17088526.
WNK protein kinases modulate cellular Cl- flux by altering the phosphorylation state of the Na-K-Cl and K-Cl cotransporters.Kahle KT, Rinehart J, Ring A, Gimenez I, Gamba G, Hebert SC, Lifton RP. Physiology (Bethesda). 2006 Oct. PMID: 16990453.
Flow-activated transport events along the nephron.Wang T. Curr Opin Nephrol Hypertens. 2006 Sep. PMID: 16914967.
Pharmacological activation and inhibition of Slack (Slo2.2) channels.Yang B, Gribkoff VK, Pan J, Damagnez V, Dworetzky SI, Boissard CG, Bhattacharjee A, Yan Y, Sigworth FJ, Kaczmarek LK. Neuropharmacology. 2006 Sep; 2006 Jul 28. PMID: 16876206.
Actin polymerization regulates clathrin coat maturation during early stages of synaptic vesicle recycling at lamprey synapses.Bourne J, Morgan JR, Pieribone VA. J Comp Neurol. 2006 Aug 1. PMID: 16739194.
An amphipathic helix targets serum and glucocorticoid-induced kinase 1 to the endoplasmic reticulum-associated ubiquitin-conjugation machinery.Arteaga MF, Wang L, Ravid T, Hochstrasser M, Canessa CM. Proc Natl Acad Sci U S A. 2006 Jul 25; 2006 Jul 17. PMID: 16847254.
Rustling synaptic vesicle cargo after exocytosis.Grabner C, Zenisek D. Neuron. 2006 Jul 6. PMID: 16815324.
Microfluidic system for planar patch clamp electrode arrays.Li X, Klemic KG, Reed MA, Sigworth FJ. Nano Lett. 2006 Apr. PMID: 16608289.
CFTR is required for PKA-regulated ATP sensitivity of Kir1.1 potassium channels in mouse kidney.Lu M, Leng Q, Egan ME, Caplan MJ, Boulpaep EL, Giebisch GH, Hebert SC. J Clin Invest. 2006 Mar; 2006 Feb 9. PMID: 16470247.
Interglomerular center-surround inhibition shapes odorant-evoked input to the mouse olfactory bulb in vivo.Vucinić D, Cohen LB, Kosmidis EK. J Neurophysiol. 2006 Mar; 2005 Nov 30. PMID: 16319205.
WNK3, a kinase related to genes mutated in hereditary hypertension with hyperkalaemia, regulates the K+ channel ROMK1 (Kir1.1).Leng Q, Kahle KT, Rinehart J, MacGregor GG, Wilson FH, Canessa CM, Lifton RP, Hebert SC. J Physiol. 2006 Mar 1; 2005 Dec 15. PMID: 16357011.
Ghrelin controls hippocampal spine synapse density and memory performance.Diano S, Farr SA, Benoit SC, McNay EC, da Silva I, Horvath B, Gaskin FS, Nonaka N, Jaeger LB, Banks WA, Morley JE, Pinto S, Sherwin RS, Xu L, Yamada KA, Sleeman MW, Tschöp MH, Horvath TL. Nat Neurosci. 2006 Mar; 2006 Feb 19. PMID: 16491079.
Axial flow modulates proximal tubule NHE3 and H-ATPase activities by changing microvillus bending moments.Du Z, Yan Q, Duan Y, Weinbaum S, Weinstein AM, Wang T. Am J Physiol Renal Physiol. 2006 Feb; 2005 Sep 6. PMID: 16144961.
Gating of acid-sensitive ion channel-1: release of Ca2+ block vs. allosteric mechanism.Zhang P, Sigworth FJ, Canessa CM. J Gen Physiol. 2006 Feb; 2006 Jan 17. PMID: 16418400.
Cryo-EM and single particles.Wang L, Sigworth FJ. Physiology (Bethesda). 2006 Feb. PMID: 16443818.
Polycystin-2 regulates proliferation and branching morphogenesis in kidney epithelial cells.Grimm DH, Karihaloo A, Cai Y, Somlo S, Cantley LG, Caplan MJ. J Biol Chem. 2006 Jan 6; 2005 Nov 8. PMID: 16278216.

2005

WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl- cotransporters required for normal blood pressure homeostasis.Rinehart J, Kahle KT, de Los Heros P, Vazquez N, Meade P, Wilson FH, Hebert SC, Gimenez I, Gamba G, Lifton RP. Proc Natl Acad Sci U S A. 2005 Nov 15; 2005 Nov 7. PMID: 16275913.
WNK3 modulates transport of Cl- in and out of cells: implications for control of cell volume and neuronal excitability.Kahle KT, Rinehart J, de Los Heros P, Louvi A, Meade P, Vazquez N, Hebert SC, Gamba G, Gimenez I, Lifton RP. Proc Natl Acad Sci U S A. 2005 Nov 15; 2005 Nov 7. PMID: 16275911.
Generation of functional fluorescent BK channels by random insertion of GFP variants.Giraldez T, Hughes TE, Sigworth FJ. J Gen Physiol. 2005 Nov. PMID: 16260837.
Proton sensitivity of ASIC1 appeared with the rise of fishes by changes of residues in the region that follows TM1 in the ectodomain of the channel.Coric T, Zheng D, Gerstein M, Canessa CM. J Physiol. 2005 Nov 1; 2005 Jul 7. PMID: 16002453.
The C-terminal tail of the polycystin-1 protein interacts with the Na,K-ATPase alpha-subunit.Zatti A, Chauvet V, Rajendran V, Kimura T, Pagel P, Caplan MJ. Mol Biol Cell. 2005 Nov; 2005 Aug 17. PMID: 16107561.
Mitochondrial uncoupling proteins in the CNS: in support of function and survival.Andrews ZB, Diano S, Horvath TL. Nat Rev Neurosci. 2005 Nov. PMID: 16224498.
Oscillations in the olfactory bulb carry information about odorant history.Zochowski MR, Cohen LB. J Neurophysiol. 2005 Oct; 2005 Jun 22. PMID: 15972833.
Role of PDZK1 in membrane expression of renal brush border ion exchangers.Thomson RB, Wang T, Thomson BR, Tarrats L, Girardi A, Mentone S, Soleimani M, Kocher O, Aronson PS. Proc Natl Acad Sci U S A. 2005 Sep 13; 2005 Sep 2. PMID: 16141316.
Suppression of hypothalamic deiodinase type II activity blunts TRH mRNA decline during fasting.Coppola A, Hughes J, Esposito E, Schiavo L, Meli R, Diano S. FEBS Lett. 2005 Aug 29. PMID: 16098513.
Recent progress towards understanding the synaptic ribbon.Prescott ED, Zenisek D. Curr Opin Neurobiol. 2005 Aug. PMID: 16023852.
Functional specificity of Sgk1 and Akt1 on ENaC activity.Arteaga MF, Canessa CM. Am J Physiol Renal Physiol. 2005 Jul. PMID: 15951481.
Inverse shift in circulating corticosterone and leptin levels elevates hypothalamic deiodinase type 2 in fasted rats.Coppola A, Meli R, Diano S. Endocrinology. 2005 Jun; 2005 Mar 3. PMID: 15746256.
Vesicle reuse revisited.Zenisek D. Proc Natl Acad Sci U S A. 2005 May 24; 2005 May 17. PMID: 15899973.
Coupling between clathrin-coated-pit invagination, cortactin recruitment, and membrane scission observed in live cells.Merrifield CJ, Perrais D, Zenisek D. Cell. 2005 May 20. PMID: 15907472.
Imaging brain activity with voltage- and calcium-sensitive dyes.Baker BJ, Kosmidis EK, Vucinic D, Falk CX, Cohen LB, Djurisic M, Zecevic D. Cell Mol Neurobiol. 2005 Mar. PMID: 16050036.
Saccharomyces cerevisiae imports the cytosolic pathway for Gln-tRNA synthesis into the mitochondrion.Rinehart J, Krett B, Rubio MA, Alfonzo JD, Söll D. Genes Dev. 2005 Mar 1; 2005 Feb 10. PMID: 15706032.
Microchip technology in ion-channel research.Sigworth FJ, Klemic KG. IEEE Trans Nanobioscience. 2005 Mar. PMID: 15816178.
An air-molding technique for fabricating PDMS planar patch-clamp electrodes.Klemic KG, Klemic JF, Sigworth FJ. Pflugers Arch. 2005 Mar; 2004 Dec 1. PMID: 15578213.
Requirement of voltage-gated calcium channel beta4 subunit for T lymphocyte functions.Badou A, Basavappa S, Desai R, Peng YQ, Matza D, Mehal WZ, Kaczmarek LK, Boulpaep EL, Flavell RA. Science. 2005 Jan 7. PMID: 15637280.
Insulin-induced phosphorylation of ENaC correlates with increased sodium channel function in A6 cells.Zhang YH, Alvarez de la Rosa D, Canessa CM, Hayslett JP. Am J Physiol Cell Physiol. 2005 Jan; 2004 Sep 8. PMID: 15355850.

2004

NHE2-mediated bicarbonate reabsorption in the distal tubule of NHE3 null mice.Bailey MA, Giebisch G, Abbiati T, Aronson PS, Gawenis LR, Shull GE, Wang T. J Physiol. 2004 Dec 15; 2004 Oct 7. PMID: 15604231.
Visualizing synaptic ribbons in the living cell.Zenisek D, Horst NK, Merrifield C, Sterling P, Matthews G. J Neurosci. 2004 Nov 3. PMID: 15525760.
Mechanical stimuli induce cleavage and nuclear translocation of the polycystin-1 C terminus.Chauvet V, Tian X, Husson H, Grimm DH, Wang T, Hiesberger T, Igarashi P, Bennett AM, Ibraghimov-Beskrovnaya O, Somlo S, Caplan MJ. J Clin Invest. 2004 Nov. PMID: 15545994.
Paracellular Cl- permeability is regulated by WNK4 kinase: insight into normal physiology and hypertension.Kahle KT, Macgregor GG, Wilson FH, Van Hoek AN, Brown D, Ardito T, Kashgarian M, Giebisch G, Hebert SC, Boulpaep EL, Lifton RP. Proc Natl Acad Sci U S A. 2004 Oct 12; 2004 Oct 1. PMID: 15465913.
A role for talin in presynaptic function.Morgan JR, Di Paolo G, Werner H, Shchedrina VA, Pypaert M, Pieribone VA, De Camilli P. J Cell Biol. 2004 Oct 11. PMID: 15479735.
Regulation of exocytosis in neurons and neuroendocrine cells.An S, Zenisek D. Curr Opin Neurobiol. 2004 Oct. PMID: 15464884.
Mechanisms of regulation of epithelial sodium channel by SGK1 in A6 cells.Alvarez de la Rosa D, Paunescu TG, Els WJ, Helman SI, Canessa CM. J Gen Physiol. 2004 Oct. PMID: 15452200.
Mechanosensory function of microvilli of the kidney proximal tubule.Du Z, Duan Y, Yan Q, Weinstein AM, Weinbaum S, Wang T. Proc Natl Acad Sci U S A. 2004 Aug 31; 2004 Aug 19. PMID: 15319475.
Can Shaker potassium channels be locked in the deactivated state?Yang Y, Yan Y, Sigworth FJ. J Gen Physiol. 2004 Aug. PMID: 15277577.
The floating blueprint of hypothalamic feeding circuits.Horvath TL, Diano S. Nat Rev Neurosci. 2004 Aug. PMID: 15263896.
Brain circuits regulating energy homeostasis.Horvath TL, Diano S, Tschöp M. Neuroscientist. 2004 Jun. PMID: 15155062.
Sorting of H,K-ATPase beta-subunit in MDCK and LLC-PK cells is independent of mu 1B adaptin expression.Duffield A, Fölsch H, Mellman I, Caplan MJ. Traffic. 2004 Jun. PMID: 15117319.
Curcumin, a major constituent of turmeric, corrects cystic fibrosis defects.Egan ME, Pearson M, Weiner SA, Rajendran V, Rubin D, Glöckner-Pagel J, Canny S, Du K, Lukacs GL, Caplan MJ. Science. 2004 Apr 23. PMID: 15105504.
The role of actin in the regulation of dendritic spine morphology and bidirectional synaptic plasticity.Chen Y, Bourne J, Pieribone VA, Fitzsimonds RM. Neuroreport. 2004 Apr 9. PMID: 15073524.
Expression of ENaC and serum- and glucocorticoid-induced kinase 1 in the rat intestinal epithelium.Coric T, Hernandez N, Alvarez de la Rosa D, Shao D, Wang T, Canessa CM. Am J Physiol Gastrointest Liver Physiol. 2004 Apr; 2003 Nov 20. PMID: 14630642.
Chloride channel function in the yeast TRK-potassium transporters.Kuroda T, Bihler H, Bashi E, Slayman CL, Rivetta A. J Membr Biol. 2004 Apr 1. PMID: 15216418.
ROMK is required for expression of the 70-pS K channel in the thick ascending limb.Lu M, Wang T, Yan Q, Wang W, Giebisch G, Hebert SC. Am J Physiol Renal Physiol. 2004 Mar; 2003 Nov 4. PMID: 14600033.
WNK4 regulates apical and basolateral Cl- flux in extrarenal epithelia.Kahle KT, Gimenez I, Hassan H, Wilson FH, Wong RD, Forbush B, Aronson PS, Lifton RP. Proc Natl Acad Sci U S A. 2004 Feb 17; 2004 Feb 9. PMID: 14769928.
Epitope tagging of the yeast K(+) carrier Trk2p demonstrates folding that is consistent with a channel-like structure.Zeng GF, Pypaert M, Slayman CL. J Biol Chem. 2004 Jan 23; 2003 Oct 21. PMID: 14570869.
Non-canonical eukaryotic glutaminyl- and glutamyl-tRNA synthetases form mitochondrial aminoacyl-tRNA in Trypanosoma brucei.Rinehart J, Horn EK, Wei D, Soll D, Schneider A. J Biol Chem. 2004 Jan 9; 2003 Oct 16. PMID: 14563839.

2003

The tetraspanin CD63 enhances the internalization of the H,K-ATPase beta-subunit.Duffield A, Kamsteeg EJ, Brown AN, Pagel P, Caplan MJ. Proc Natl Acad Sci U S A. 2003 Dec 23; 2003 Dec 5. PMID: 14660791.
Slick (Slo2.1), a rapidly-gating sodium-activated potassium channel inhibited by ATP.Bhattacharjee A, Joiner WJ, Wu M, Yang Y, Sigworth FJ, Kaczmarek LK. J Neurosci. 2003 Dec 17. PMID: 14684870.
The extracellular domain determines the kinetics of desensitization in acid-sensitive ion channel 1.Coric T, Zhang P, Todorovic N, Canessa CM. J Biol Chem. 2003 Nov 14; 2003 Aug 28. PMID: 12947112.
Uncoupling protein 2 prevents neuronal death including that occurring during seizures: a mechanism for preconditioning.Diano S, Matthews RT, Patrylo P, Yang L, Beal MF, Barnstable CJ, Horvath TL. Endocrinology. 2003 Nov; 2003 Aug 21. PMID: 12960023.
Midbrain serotonergic neurons are central pH chemoreceptors.Severson CA, Wang W, Pieribone VA, Dohle CI, Richerson GB. Nat Neurosci. 2003 Nov; 2003 Sep 28. PMID: 14517544.
Polycystin-1 distribution is modulated by polycystin-2 expression in mammalian cells.Grimm DH, Cai Y, Chauvet V, Rajendran V, Zeltner R, Geng L, Avner ED, Sweeney W, Somlo S, Caplan MJ. J Biol Chem. 2003 Sep 19; 2003 Jul 2. PMID: 12840011.
Calcium-dependent, swelling-activated K+ conductance in human neuroblastoma cells.Basavappa S, Mangel AW, Boulpaep EL. Biochem Biophys Res Commun. 2003 Sep 5. PMID: 12927783.
Inhibition of heme oxygenase decreases sodium and fluid absorption in the loop of Henle.Wang T, Sterling H, Shao WA, Yan Q, Bailey MA, Giebisch G, Wang WH. Am J Physiol Renal Physiol. 2003 Sep. PMID: 12890663.
Fasting activates the nonhuman primate hypocretin (orexin) system and its postsynaptic targets.Diano S, Horvath B, Urbanski HF, Sotonyi P, Horvath TL. Endocrinology. 2003 Sep. PMID: 12933647.
Distribution and regulation of expression of serum- and glucocorticoid-induced kinase-1 in the rat kidney.Alvarez de la Rosa D, Coric T, Todorovic N, Shao D, Wang T, Canessa CM. J Physiol. 2003 Sep 1; 2003 Jun 19. PMID: 12816971.
Imaging nervous system activity with voltage-sensitive dyes.Zecevic D, Djurisic M, Cohen LB, Antic S, Wachowiak M, Falk CX, Zochowski MR. Curr Protoc Neurosci. 2003 Aug. PMID: 18428582.
PASK (proline-alanine-rich STE20-related kinase), a regulatory kinase of the Na-K-Cl cotransporter (NKCC1).Dowd BF, Forbush B. J Biol Chem. 2003 Jul 25; 2003 May 9. PMID: 12740379.
Short-term stimulation of the renal Na-K-Cl cotransporter (NKCC2) by vasopressin involves phosphorylation and membrane translocation of the protein.Giménez I, Forbush B. J Biol Chem. 2003 Jul 18; 2003 May 5. PMID: 12732642.
Active K+ secretion through multiple KCa-type channels and regulation by IKCa channels in rat proximal colon.Joiner WJ, Basavappa S, Vidyasagar S, Nehrke K, Krishnan S, Binder HJ, Boulpaep EL, Rajendran VM. Am J Physiol Gastrointest Liver Physiol. 2003 Jul; 2003 Feb 26. PMID: 12606302.
Coenzyme Q induces nigral mitochondrial uncoupling and prevents dopamine cell loss in a primate model of Parkinson's disease.Horvath TL, Diano S, Leranth C, Garcia-Segura LM, Cowley MA, Shanabrough M, Elsworth JD, Sotonyi P, Roth RH, Dietrich EH, Matthews RT, Barnstable CJ, Redmond DE Jr. Endocrinology. 2003 Jul. PMID: 12810526.
Hypothalamic type II iodothyronine deiodinase: a light and electron microscopic study.Diano S, Leonard JL, Meli R, Esposito E, Schiavo L. Brain Res. 2003 Jun 20. PMID: 12763631.
Mitochondrial uncoupling protein 2 in the central nervous system: neuromodulator and neuroprotector.Horvath TL, Diano S, Barnstable C. Biochem Pharmacol. 2003 Jun 15. PMID: 12787871.
Colocalization of synapsin and actin during synaptic vesicle recycling.Bloom O, Evergren E, Tomilin N, Kjaerulff O, Löw P, Brodin L, Pieribone VA, Greengard P, Shupliakov O. J Cell Biol. 2003 May 26; 2003 May 19. PMID: 12756235.
Role of PKC and calcium in modulation of effects of angiotensin II on sodium transport in proximal tubule.Du Z, Ferguson W, Wang T. Am J Physiol Renal Physiol. 2003 Apr; 2003 Jan 14. PMID: 12527554.
Ion pump-interacting proteins: promising new partners.Pagel P, Zatti A, Kimura T, Duffield A, Chauvet V, Rajendran V, Caplan MJ. Ann N Y Acad Sci. 2003 Apr. PMID: 12763851.
Uncoupling proteins-2 and 3 influence obesity and inflammation in transgenic mice.Horvath TL, Diano S, Miyamoto S, Barry S, Gatti S, Alberati D, Livak F, Lombardi A, Moreno M, Goglia F, Mor G, Hamilton J, Kachinskas D, Horwitz B, Warden CH. Int J Obes Relat Metab Disord. 2003 Apr. PMID: 12664076.
Imaging calcium entry sites and ribbon structures in two presynaptic cells.Zenisek D, Davila V, Wan L, Almers W. J Neurosci. 2003 Apr 1. PMID: 12684438.
Correspondence between odorant-evoked patterns of receptor neuron input and intrinsic optical signals in the mouse olfactory bulb.Wachowiak M, Cohen LB. J Neurophysiol. 2003 Mar; 2002 Oct 23. PMID: 12612023.
Role of SGK in hormonal regulation of epithelial sodium channel in A6 cells.Alvarez de la Rosa D, Canessa CM. Am J Physiol Cell Physiol. 2003 Feb; 2002 Oct 16. PMID: 12388075.
Odorant specificity of three oscillations and the DC signal in the turtle olfactory bulb.Lam YW, Cohen LB, Zochowski MR. Eur J Neurosci. 2003 Feb. PMID: 12581162.
The effects of the potassium channel opener minoxidil on renal electrolytes transport in the loop of henle.Wang T. J Pharmacol Exp Ther. 2003 Feb. PMID: 12538840.
Distribution, subcellular localization and ontogeny of ASIC1 in the mammalian central nervous system.Alvarez de la Rosa D, Krueger SR, Kolar A, Shao D, Fitzsimonds RM, Canessa CM. J Physiol. 2003 Jan 1. PMID: 12509480.

2002

Orthologs of a novel archaeal and of the bacterial peptidyl-tRNA hydrolase are nonessential in yeast.Rosas-Sandoval G, Ambrogelly A, Rinehart J, Wei D, Cruz-Vera LR, Graham DE, Stetter KO, Guarneros G, Söll D. Proc Natl Acad Sci U S A. 2002 Dec 24; 2002 Dec 10. PMID: 12475929.
Expression of synapsin III in nerve terminals and neurogenic regions of the adult brain.Pieribone VA, Porton B, Rendon B, Feng J, Greengard P, Kao HT. J Comp Neurol. 2002 Dec 9. PMID: 12412137.
Activation of the Na-K-Cl cotransporter NKCC1 detected with a phospho-specific antibody.Flemmer AW, Gimenez I, Dowd BF, Darman RB, Forbush B. J Biol Chem. 2002 Oct 4; 2002 Jul 26. PMID: 12145305.
A regulatory locus of phosphorylation in the N terminus of the Na-K-Cl cotransporter, NKCC1.Darman RB, Forbush B. J Biol Chem. 2002 Oct 4; 2002 Jul 26. PMID: 12145304.
Absence of small conductance K+ channel (SK) activity in apical membranes of thick ascending limb and cortical collecting duct in ROMK (Bartter's) knockout mice.Lu M, Wang T, Yan Q, Yang X, Dong K, Knepper MA, Wang W, Giebisch G, Shull GE, Hebert SC. J Biol Chem. 2002 Oct 4; 2002 Jul 18. PMID: 12130653.
Role of iNOS and eNOS in modulating proximal tubule transport and acid-base balance.Wang T. Am J Physiol Renal Physiol. 2002 Oct. PMID: 12217856.
Single channel properties of rat acid-sensitive ion channel-1alpha, -2a, and -3 expressed in Xenopus oocytes.Zhang P, Canessa CM. J Gen Physiol. 2002 Oct. PMID: 12356856.
Presynaptic inhibition of olfactory receptor neurons in crustaceans.Wachowiak M, Cohen LB, Ache BW. Microsc Res Tech. 2002 Aug 15. PMID: 12214303.
Extracellular domains, transmembrane segments, and intracellular domains interact to determine the cation selectivity of Na,K- and gastric H,K-ATPase.Mense M, Rajendran V, Blostein R, Caplan MJ. Biochemistry. 2002 Aug 6. PMID: 12146946.
Three-dimensional structure of the type 1 inositol 1,4,5-trisphosphate receptor at 24 A resolution.Jiang QX, Thrower EC, Chester DW, Ehrlich BE, Sigworth FJ. EMBO J. 2002 Jul 15. PMID: 12110570.
Patch clamp on a chip.Sigworth FJ, Klemic KG. Biophys J. 2002 Jun. PMID: 12023207.
Micromolded PDMS planar electrode allows patch clamp electrical recordings from cells.Klemic KG, Klemic JF, Reed MA, Sigworth FJ. Biosens Bioelectron. 2002 Jun. PMID: 11959483.
Effects of aldosterone on biosynthesis, traffic, and functional expression of epithelial sodium channels in A6 cells.Alvarez de la Rosa D, Li H, Canessa CM. J Gen Physiol. 2002 May. PMID: 11981022.
Calcium-pump inhibitors induce functional surface expression of Delta F508-CFTR protein in cystic fibrosis epithelial cells.Egan ME, Glöckner-Pagel J, Ambrose C, Cahill PA, Pappoe L, Balamuth N, Cho E, Canny S, Wagner CA, Geibel J, Caplan MJ. Nat Med. 2002 May. PMID: 11984593.
Chemosensitive serotonergic neurons are closely associated with large medullary arteries.Bradley SR, Pieribone VA, Wang W, Severson CA, Jacobs RA, Richerson GB. Nat Neurosci. 2002 May. PMID: 11967547.
Spatially distributed alternative splice variants of the renal Na-K-Cl cotransporter exhibit dramatically different affinities for the transported ions.Giménez I, Isenring P, Forbush B. J Biol Chem. 2002 Mar 15; 2002 Jan 28. PMID: 11815599.
Functional implications of the localization and activity of acid-sensitive channels in rat peripheral nervous system.Alvarez de la Rosa D, Zhang P, Shao D, White F, Canessa CM. Proc Natl Acad Sci U S A. 2002 Feb 19; 2002 Feb 12. PMID: 11842212.
Distributed and concentration-invariant spatial representations of odorants by receptor neuron input to the turtle olfactory bulb.Wachowiak M, Cohen LB, Zochowski MR. J Neurophysiol. 2002 Feb. PMID: 11826067.
A genetically targetable fluorescent probe of channel gating with rapid kinetics.Ataka K, Pieribone VA. Biophys J. 2002 Jan. PMID: 11751337.

2001

The NH(2)-terminus of norepinephrine transporter contains a basolateral localization signal for epithelial cells.Gu HH, Wu X, Giros B, Caron MG, Caplan MJ, Rudnick G. Mol Biol Cell. 2001 Dec. PMID: 11739781.
Representation of odorants by receptor neuron input to the mouse olfactory bulb.Wachowiak M, Cohen LB. Neuron. 2001 Nov 20. PMID: 11719211.
Potassium channel mechanics.Sigworth FJ. Neuron. 2001 Nov 20. PMID: 11719196.
Hidden Markov model analysis of intermediate gating steps associated with the pore gate of shaker potassium channels.Zheng J, Vankataramanan L, Sigworth FJ. J Gen Physiol. 2001 Nov. PMID: 11696611.
Minireview: ghrelin and the regulation of energy balance--a hypothalamic perspective.Horvath TL, Diano S, Sotonyi P, Heiman M, Tschöp M. Endocrinology. 2001 Oct. PMID: 11564668.
Modulation of ion transport by direct targeting of protein phosphatase type 1 to the Na-K-Cl cotransporter.Darman RB, Flemmer A, Forbush B. J Biol Chem. 2001 Sep 14; 2001 Jul 20. PMID: 11466303.
Ion pumps in polarized cells: sorting and regulation of the Na+, K+- and H+, K+-ATPases.Dunbar LA, Caplan MJ. J Biol Chem. 2001 Aug 10; 2001 Jun 12. PMID: 11404365.
Cl(-)-dependent secretory mechanisms in isolated rat bile duct epithelial units.Singh SK, Mennone A, Gigliozzi A, Fraioli F, Boyer JL. Am J Physiol Gastrointest Liver Physiol. 2001 Aug. PMID: 11447024.
Ion pump sorting in polarized renal epithelial cells.Caplan MJ. Kidney Int. 2001 Aug. PMID: 11473621.
Single-channel properties of recombinant acid-sensitive ion channels formed by the subunits ASIC2 and ASIC3 from dorsal root ganglion neurons expressed in Xenopus oocytes.Zhang P, Canessa CM. J Gen Physiol. 2001 Jun. PMID: 11382806.
The C-terminal tail of the metabotropic glutamate receptor subtype 7 is necessary but not sufficient for cell surface delivery and polarized targeting in neurons and epithelia.McCarthy JB, Lim ST, Elkind NB, Trimmer JS, Duvoisin RM, Rodriguez-Boulan E, Caplan MJ. J Biol Chem. 2001 Mar 23; 2000 Dec 5. PMID: 11106656.
A GABA-neuropeptide Y (NPY) interplay in LH release.Horvath TL, Pu S, Dube MG, Diano S, Kalra SP. Peptides. 2001 Mar. PMID: 11287104.
Electrostatics and the gating pore of Shaker potassium channels.Islas LD, Sigworth FJ. J Gen Physiol. 2001 Jan. PMID: 11134232.

2000

Distributed and partially separate pools of neurons are correlated with two different components of the gill-withdrawal reflex in Aplysia.Zochowski M, Cohen LB, Fuhrmann G, Kleinfeld D. J Neurosci. 2000 Nov 15. PMID: 11069956.
Mitochondrial uncoupling protein 2 (UCP2) in the nonhuman primate brain and pituitary.Diano S, Urbanski HF, Horvath B, Bechmann I, Kagiya A, Nemeth G, Naftolin F, Warden CH, Horvath TL. Endocrinology. 2000 Nov. PMID: 11089557.
Basolateral K-Cl cotransporter regulates colonic potassium absorption in potassium depletion.Sangan P, Brill SR, Sangan S, Forbush B 3rd, Binder HJ. J Biol Chem. 2000 Oct 6. PMID: 10878016.
The spatial representation of odors by olfactory receptor neuron input to the olfactory bulb is concentration invariant.Wachowiak M, Zochowski M, Cohen LB, Falk CX. Biol Bull. 2000 Oct. PMID: 11081714.
Heterologous expression of a mammalian epithelial sodium channel in yeast.Gupta SS, Canessa CM. FEBS Lett. 2000 Sep 8. PMID: 10984619.
The cell biology of ion pumps: sorting and regulation.Dunbar LA, Caplan MJ. Eur J Cell Biol. 2000 Aug. PMID: 11001492.
An electroneutral sodium/bicarbonate cotransporter NBCn1 and associated sodium channel.Choi I, Aalkjaer C, Boulpaep EL, Boron WF. Nature. 2000 Jun 1. PMID: 10850716.
A transmembrane segment determines the steady-state localization of an ion-transporting adenosine triphosphatase.Dunbar LA, Aronson P, Caplan MJ. J Cell Biol. 2000 Feb 21. PMID: 10684257.
Imaging membrane potential with voltage-sensitive dyes.Zochowski M, Wachowiak M, Falk CX, Cohen LB, Lam YW, Antic S, Zecevic D. Biol Bull. 2000 Feb. PMID: 10707808.
Residues of the fourth transmembrane segments of the Na,K-ATPase and the gastric H,K-ATPase contribute to cation selectivity.Mense M, Dunbar LA, Blostein R, Caplan MJ. J Biol Chem. 2000 Jan 21. PMID: 10636871.
Odors elicit three different oscillations in the turtle olfactory bulb.Lam YW, Cohen LB, Wachowiak M, Zochowski MR. J Neurosci. 2000 Jan 15. PMID: 10632604.

1999

The serum and glucocorticoid kinase sgk increases the abundance of epithelial sodium channels in the plasma membrane of Xenopus oocytes.Alvarez de la Rosa D, Zhang P, Náray-Fejes-Tóth A, Fejes-Tóth G, Canessa CM. J Biol Chem. 1999 Dec 31. PMID: 10608847.
The second hydrophobic domain contributes to the kinetic properties of epithelial sodium channels.Fyfe GK, Zhang P, Canessa CM. J Biol Chem. 1999 Dec 17. PMID: 10593937.
Hypocretin (orexin) activation and synaptic innervation of the locus coeruleus noradrenergic system.Horvath TL, Peyron C, Diano S, Ivanov A, Aston-Jones G, Kilduff TS, van Den Pol AN. J Comp Neurol. 1999 Dec 13. PMID: 10545156.
Inhibition of alphabeta epithelial sodium channels by external protons indicates that the second hydrophobic domain contains structural elements for closing the pore.Zhang P, Fyfe GK, Grichtchenko II, Canessa CM. Biophys J. 1999 Dec. PMID: 10585926.
Fast multisite optical measurement of membrane potential: three examples.Antic S, Cohen LB, Lam YW, Wachowiak M, Zecevic D, Zochowski M. FASEB J. 1999 Dec. PMID: 10619142.
Brain uncoupling protein 2: uncoupled neuronal mitochondria predict thermal synapses in homeostatic centers.Horvath TL, Warden CH, Hajos M, Lombardi A, Goglia F, Diano S. J Neurosci. 1999 Dec 1. PMID: 10575039.
Voltage sensitivity and gating charge in Shaker and Shab family potassium channels.Islas LD, Sigworth FJ. J Gen Physiol. 1999 Nov. PMID: 10539976.
Presynaptic inhibition of primary olfactory afferents mediated by different mechanisms in lobster and turtle.Wachowiak M, Cohen LB. J Neurosci. 1999 Oct 15. PMID: 10516300.
Estrogen receptor beta and progesterone receptor mRNA in the intergeniculate leaflet of the female rat.Horvath TL, Diano S, Sakamoto H, Shughrue PJ, Merchenthaler I. Brain Res. 1999 Oct 9. PMID: 10536277.
Nongastric H+,K+-ATPase: cell biologic and functional properties.Grishin AV, Reinhard J, Dunbar LA, Courtois-Coutry N, Wang T, Giebisch G, Caplan MJ. Semin Nephrol. 1999 Sep. PMID: 10511382.
Regulation of myocardial glucose uptake and transport during ischemia and energetic stress.Young LH, Russell RR 3rd, Yin R, Caplan MJ, Ren J, Bergeron R, Shulman GI, Sinusas AJ. Am J Cardiol. 1999 Jun 17. PMID: 10750583.
The presumed potassium carrier Trk2p in Saccharomyces cerevisiae determines an H+-dependent, K+-independent current.Bihler H, Gaber RF, Slayman CL, Bertl A. FEBS Lett. 1999 Mar 19. PMID: 10218594.
Functional interaction of the K-Cl cotransporter (KCC1) with the Na-K-Cl cotransporter in HEK-293 cells.Gillen CM, Forbush B 3rd. Am J Physiol. 1999 Feb. PMID: 9950760.
Synaptic interaction between hypocretin (orexin) and neuropeptide Y cells in the rodent and primate hypothalamus: a novel circuit implicated in metabolic and endocrine regulations.Horvath TL, Diano S, van den Pol AN. J Neurosci. 1999 Feb 1. PMID: 9920670.
Immunolocalization of the electrogenic Na+-HCO-3 cotransporter in mammalian and amphibian kidney.Schmitt BM, Biemesderfer D, Romero MF, Boulpaep EL, Boron WF. Am J Physiol. 1999 Jan. PMID: 9887077.

1998

Electrophysiologic effects of galanin on neurons of the central nervous system.Pieribone VA, Xu ZQ, Zhang X, Hökfelt T. Ann N Y Acad Sci. 1998 Dec 21. PMID: 9928177.
Single-channel properties of IKs potassium channels.Yang Y, Sigworth FJ. J Gen Physiol. 1998 Dec. PMID: 9834139.
Macrophages, estrogen and the microenvironment of breast cancer.Mor G, Yue W, Santen RJ, Gutierrez L, Eliza M, Berstein LM, Harada N, Wang J, Lysiak J, Diano S, Naftolin F. J Steroid Biochem Mol Biol. 1998 Dec. PMID: 10030689.
Leptin receptors in estrogen receptor-containing neurons of the female rat hypothalamus.Diano S, Kalra SP, Sakamoto H, Horvath TL. Brain Res. 1998 Nov 23. PMID: 9813356.
Additive effects of hyperinsulinemia and ischemia on myocardial GLUT1 and GLUT4 translocation in vivo.Russell RR 3rd, Yin R, Caplan MJ, Hu X, Ren J, Shulman GI, Sinusas AJ, Young LH. Circulation. 1998 Nov 17. PMID: 9815873.
Biosynthesis and processing of epithelial sodium channels in Xenopus oocytes.Valentijn JA, Fyfe GK, Canessa CM. J Biol Chem. 1998 Nov 13. PMID: 9804797.
A tyrosine-based signal regulates H-K-ATPase-mediated potassium reabsorption in the kidney.Wang T, Courtois-Coutry N, Giebisch G, Caplan MJ. Am J Physiol. 1998 Nov. PMID: 9815140.
Mutagenic mapping of the Na-K-Cl cotransporter for domains involved in ion transport and bumetanide binding.Isenring P, Jacoby SC, Chang J, Forbush B. J Gen Physiol. 1998 Nov. PMID: 9806964.
Transcellular chloride pathways in ambystoma proximal tubule.Abdulnour-Nakhoul S, Boulpaep EL. J Membr Biol. 1998 Nov 1. PMID: 9784583.
ATP1AL1, a member of the non-gastric H,K-ATPase family, functions as a sodium pump.Grishin AV, Caplan MJ. J Biol Chem. 1998 Oct 23. PMID: 9774385.
Tyrosine-based membrane protein sorting signals are differentially interpreted by polarized Madin-Darby canine kidney and LLC-PK1 epithelial cells.Roush DL, Gottardi CJ, Naim HY, Roth MG, Caplan MJ. J Biol Chem. 1998 Oct 9. PMID: 9756932.
Identification of sorting determinants in the C-terminal cytoplasmic tails of the gamma-aminobutyric acid transporters GAT-2 and GAT-3.Muth TR, Ahn J, Caplan MJ. J Biol Chem. 1998 Oct 2. PMID: 9748227.
Intermediate conductances during deactivation of heteromultimeric Shaker potassium channels.Zheng J, Sigworth FJ. J Gen Physiol. 1998 Oct. PMID: 9758864.
Subunit composition determines the single channel kinetics of the epithelial sodium channel.Fyfe GK, Canessa CM. J Gen Physiol. 1998 Oct. PMID: 9758861.
Monosynaptic pathway between the arcuate nucleus expressing glial type II iodothyronine 5'-deiodinase mRNA and the median eminence-projective TRH cells of the rat paraventricular nucleus.Diano S, Naftolin F, Goglia F, Csernus V, Horvath TL. J Neuroendocrinol. 1998 Oct. PMID: 9792325.
Segregation of the intra- and extrahypothalamic neuropeptide Y and catecholaminergic inputs on paraventricular neurons, including those producing thyrotropin-releasing hormone.Diano S, Naftolin F, Goglia F, Horvath TL. Regul Pept. 1998 Sep 25. PMID: 9802401.
Leptin receptor immunoreactivity is associated with the Golgi apparatus of hypothalamic neurons and glial cells.Diano S, Kalra SP, Horvath TL. J Neuroendocrinol. 1998 Sep. PMID: 9744481.
Sorting of P-type ATPases in polarized epithelial cells.Dunbar LA, Courtois-Coutry N, Roush DL, Muth TR, Gottardi CJ, Rajendran V, Geibel J, Kashgarian M, Caplan MJ. Acta Physiol Scand Suppl. 1998 Aug. PMID: 9789572.
Gastric H+/K(+)-ATPase: targeting signals in the regulation of physiologic function.Caplan MJ. Curr Opin Cell Biol. 1998 Aug. PMID: 9719867.
NSC1: a novel high-current inward rectifier for cations in the plasma membrane of Saccharomyces cerevisiae.Bihler H, Slayman CL, Bertl A. FEBS Lett. 1998 Jul 31. PMID: 9710251.
The role of transmembrane domain 2 in cation transport by the Na-K-Cl cotransporter.Isenring P, Jacoby SC, Forbush B 3rd. Proc Natl Acad Sci U S A. 1998 Jun 9. PMID: 9618559.
Fasting-induced increase in type II iodothyronine deiodinase activity and messenger ribonucleic acid levels is not reversed by thyroxine in the rat hypothalamus.Diano S, Naftolin F, Goglia F, Horvath TL. Endocrinology. 1998 Jun. PMID: 9607797.
Comparison of Na-K-Cl cotransporters. NKCC1, NKCC2, and the HEK cell Na-L-Cl cotransporter.Isenring P, Jacoby SC, Payne JA, Forbush B 3rd. J Biol Chem. 1998 May 1. PMID: 9556622.
Kainate glutamate receptors (GluR5-7) in the rat arcuate nucleus: relationship to tanycytes, astrocytes, neurons and gonadal steroid receptors.Diano S, Naftolin F, Horvath TL. J Neuroendocrinol. 1998 Apr. PMID: 9630393.
In vivo phosphorylation of the epithelial sodium channel.Shimkets RA, Lifton R, Canessa CM. Proc Natl Acad Sci U S A. 1998 Mar 17. PMID: 9501257.
A basolateral sorting signal is encoded in the alpha-subunit of Na-K-ATPase.Muth TR, Gottardi CJ, Roush DL, Caplan MJ. Am J Physiol. 1998 Mar. PMID: 9530100.
Structure and function of the Mec-ENaC family of ion channels.Fyfe GK, Quinn A, Canessa CM. Semin Nephrol. 1998 Mar. PMID: 9541269.
Differential localization of colonic H(+)-K(+)-ATPase isoforms in surface and crypt cells.Rajendran VM, Singh SK, Geibel J, Binder HJ. Am J Physiol. 1998 Feb. PMID: 9486199.
Activation of Shaker potassium channels. III. An activation gating model for wild-type and V2 mutant channels.Schoppa NE, Sigworth FJ. J Gen Physiol. 1998 Feb. PMID: 9450946.
Activation of Shaker potassium channels. II. Kinetics of the V2 mutant channel.Schoppa NE, Sigworth FJ. J Gen Physiol. 1998 Feb. PMID: 9450945.
Activation of shaker potassium channels. I. Characterization of voltage-dependent transitions.Schoppa NE, Sigworth FJ. J Gen Physiol. 1998 Feb. PMID: 9450944.
Regulation of an inwardly rectifying ATP-sensitive K+ channel in the basolateral membrane of renal proximal tubule.Mauerer UR, Boulpaep EL, Segal AS. J Gen Physiol. 1998 Jan. PMID: 9417142.
Properties of an inwardly rectifying ATP-sensitive K+ channel in the basolateral membrane of renal proximal tubule.Mauerer UR, Boulpaep EL, Segal AS. J Gen Physiol. 1998 Jan. PMID: 9417141.

1997

Sorting of ion pumps in polarized epithelial cells.Dunbar LA, Roush DL, Courtois-Coutry N, Muth TR, Gottardi CJ, Rajendran V, Geibel J, Kashgarian M, Caplan MJ. Ann N Y Acad Sci. 1997 Nov 3. PMID: 9405853.
The activity of the epithelial sodium channel is regulated by clathrin-mediated endocytosis.Shimkets RA, Lifton RP, Canessa CM. J Biol Chem. 1997 Oct 10. PMID: 9325269.
Novel transport properties of colonic crypt cells: fluid absorption and Cl-dependent Na-H exchange.Binder HJ, Singh SK, Geibel JP, Rajendran VM. Comp Biochem Physiol A Physiol. 1997 Oct. PMID: 9366054.
Ion and bumetanide binding by the Na-K-Cl cotransporter. Importance of transmembrane domains.Isenring P, Forbush B 3rd. J Biol Chem. 1997 Sep 26. PMID: 9305921.
Sorting and trafficking of ion transport proteins in polarized epithelial cells.Muth TR, Dunbar LA, Cortois-Coutry N, Roush DL, Caplan MJ. Curr Opin Nephrol Hypertens. 1997 Sep. PMID: 9327204.
A tyrosine-based signal targets H/K-ATPase to a regulated compartment and is required for the cessation of gastric acid secretion.Courtois-Coutry N, Roush D, Rajendran V, McCarthy JB, Geibel J, Kashgarian M, Caplan MJ. Cell. 1997 Aug 8. PMID: 9267030.
Selectivity changes during activation of mutant Shaker potassium channels.Zheng J, Sigworth FJ. J Gen Physiol. 1997 Aug. PMID: 9236204.
Tubule electrophysiology: from single channels back to the renal epithelium.Boulpaep EL. Wien Klin Wochenschr. 1997 Jun 27. PMID: 9261991.
The electrogenic Na/HCO3 cotransporter.Boron WF, Fong P, Hediger MA, Boulpaep EL, Romero MF. Wien Klin Wochenschr. 1997 Jun 27. PMID: 9261985.
Ion pumps in epithelial cells: sorting, stabilization, and polarity.Caplan MJ. Am J Physiol. 1997 Jun. PMID: 9227464.
How does the W434F mutation block current in Shaker potassium channels?Yang Y, Yan Y, Sigworth FJ. J Gen Physiol. 1997 Jun. PMID: 9222903.
Diversity of channels generated by different combinations of epithelial sodium channel subunits.McNicholas CM, Canessa CM. J Gen Physiol. 1997 Jun. PMID: 9222895.
Enhanced closed-state inactivation in a mutant Shaker K+ channel.Ayer RK Jr, Sigworth FJ. J Membr Biol. 1997 Jun 1. PMID: 9178609.
Expression cloning and characterization of a renal electrogenic Na+/HCO3- cotransporter.Romero MF, Hediger MA, Boulpaep EL, Boron WF. Nature. 1997 May 22. PMID: 9163427.
Membrane polarity in epithelial cells: protein sorting and establishment of polarized domains.Caplan MJ. Am J Physiol. 1997 Apr. PMID: 9140041.
The synapse between LE sensory neurons and gill motoneurons makes only a small contribution to the Aplysia gill-withdrawal reflex.Hickie C, Cohen LB, Balaban PM. Eur J Neurosci. 1997 Apr. PMID: 9153569.
Gonadal steroids target AMPA glutamate receptor-containing neurons in the rat hypothalamus, septum and amygdala: a morphological and biochemical study.Diano S, Naftolin F, Horvath TL. Endocrinology. 1997 Feb. PMID: 9003015.
Role of the S3-S4 linker in Shaker potassium channel activation.Mathur R, Zheng J, Yan Y, Sigworth FJ. J Gen Physiol. 1997 Feb. PMID: 9041448.
The renal electrogenic Na+:HCO-3 cotransporter.Boron VF, Hediger MA, Boulpaep EL, Romero MF. J Exp Biol. 1997 Jan. PMID: 9050234.

1996

Dye screening and signal-to-noise ratio for retrogradely transported voltage-sensitive dyes.Tsau Y, Wenner P, O'Donovan MJ, Cohen LB, Loew LM, Wuskell JP. J Neurosci Methods. 1996 Dec 28. PMID: 9007751.
Sorting of GABA transporter proteins in polarized cells.Caplan MJ. Neurochem Int. 1996 Oct. PMID: 8939443.
Immunolocalization of ion transport proteins in human autosomal dominant polycystic kidney epithelial cells.Brill SR, Ross KE, Davidow CJ, Ye M, Grantham JJ, Caplan MJ. Proc Natl Acad Sci U S A. 1996 Sep 17. PMID: 8816777.
Functional expression of the cDNA encoded by the human ATP1AL1 gene.Grishin AV, Bevensee MO, Modyanov NN, Rajendran V, Boron WF, Caplan MJ. Am J Physiol. 1996 Sep. PMID: 8853415.
Effect of feedback from peripheral movements on neuron activity in the aplysia abdominal ganglion.Höpp HP, Falk CX, Cohen LB, Wu JY, Cohen AI. Eur J Neurosci. 1996 Sep. PMID: 8921277.
Cell-specific sorting of biogenic amine transporters expressed in epithelial cells.Gu HH, Ahn J, Caplan MJ, Blakely RD, Levey AI, Rudnick G. J Biol Chem. 1996 Jul 26. PMID: 8663573.
Real-time detection of the surface delivery of newly synthesized membrane proteins.Andreose JS, Fumagalli G, Sigworth FJ, Caplan MJ. Proc Natl Acad Sci U S A. 1996 Jul 23. PMID: 8755532.
Molecular cloning and functional expression of the K-Cl cotransporter from rabbit, rat, and human. A new member of the cation-chloride cotransporter family.Gillen CM, Brill S, Payne JA, Forbush B 3rd. J Biol Chem. 1996 Jul 5. PMID: 8663127.
Impaired slow inactivation in mutant sodium channels.Cummins TR, Sigworth FJ. Biophys J. 1996 Jul. PMID: 8804606.
Immunocytochemical studies of the Na-K-Cl cotransporter of shark kidney.Biemesderfer D, Payne JA, Lytle CY, Forbush B 3rd. Am J Physiol. 1996 Jun. PMID: 8764311.
A novel preparation of dissociated renal proximal tubule cells that maintain epithelial polarity in suspension.Segal AS, Boulpaep EL, Maunsbach AB. Am J Physiol. 1996 Jun. PMID: 8764170.
Molecular cloning of a glibenclamide-sensitive, voltage-gated potassium channel expressed in rabbit kidney.Yao X, Chang AY, Boulpaep EL, Segal AS, Desir GV. J Clin Invest. 1996 Jun 1. PMID: 8647945.
Polarized expression of GABA transporters in Madin-Darby canine kidney cells and cultured hippocampal neurons.Ahn J, Mundigl O, Muth TR, Rudnick G, Caplan MJ. J Biol Chem. 1996 Mar 22. PMID: 8636119.

1995

Primary structure and functional expression of a cGMP-gated potassium channel.Yao X, Segal AS, Welling P, Zhang X, McNicholas CM, Engel D, Boulpaep EL, Desir GV. Proc Natl Acad Sci U S A. 1995 Dec 5. PMID: 8524834.
An apical permeability barrier to NH3/NH4+ in isolated, perfused colonic crypts.Singh SK, Binder HJ, Geibel JP, Boron WF. Proc Natl Acad Sci U S A. 1995 Dec 5. PMID: 8524806.
Distribution and diversity of Na-K-Cl cotransport proteins: a study with monoclonal antibodies.Lytle C, Xu JC, Biemesderfer D, Forbush B 3rd. Am J Physiol. 1995 Dec. PMID: 8572179.
Charge movement in the sodium channel.Sigworth FJ. J Gen Physiol. 1995 Dec. PMID: 8786349.
Fluid absorption in isolated perfused colonic crypts.Singh SK, Binder HJ, Boron WF, Geibel JP. J Clin Invest. 1995 Nov. PMID: 7593625.
Expression cloning of the epithelial sodium channel.Canessa CM, Horisberger JD, Schild L, Rossier BC. Kidney Int. 1995 Oct. PMID: 8569104.
Cloning, embryonic expression, and alternative splicing of a murine kidney-specific Na-K-Cl cotransporter.Igarashi P, Vanden Heuvel GB, Payne JA, Forbush B 3rd. Am J Physiol. 1995 Sep. PMID: 7573490.
Localization of the renal Na-K-Cl cotransporter gene (Slc12a1) on mouse chromosome 2.Quaggin SE, Payne JA, Forbush B 3rd, Igarashi P. Mamm Genome. 1995 Aug. PMID: 8589530.
Primary structure, functional expression, and chromosomal localization of the bumetanide-sensitive Na-K-Cl cotransporter in human colon.Payne JA, Xu JC, Haas M, Lytle CY, Ward D, Forbush B 3rd. J Biol Chem. 1995 Jul 28. PMID: 7629105.
Developmental regulation of membrane protein sorting in Drosophila embryos.Shiel MJ, Caplan MJ. Am J Physiol. 1995 Jul. PMID: 7631747.
Use of Saccharomyces cerevisiae for patch-clamp analysis of heterologous membrane proteins: characterization of Kat1, an inward-rectifying K+ channel from Arabidopsis thaliana, and comparison with endogeneous yeast channels and carriers.Bertl A, Anderson JA, Slayman CL, Gaber RF. Proc Natl Acad Sci U S A. 1995 Mar 28. PMID: 7708709.
Biotinylation and assessment of membrane polarity: caveats and methodological concerns.Gottardi CJ, Dunbar LA, Caplan MJ. Am J Physiol. 1995 Feb. PMID: 7864168.
Design of the EPC-9, a computer-controlled patch-clamp amplifier. 2. Software.Sigworth FJ, Affolter H, Neher E. J Neurosci Methods. 1995 Feb. PMID: 7538621.
Design of the EPC-9, a computer-controlled patch-clamp amplifier. 1. Hardware.SIGWorth FJ. J Neurosci Methods. 1995 Feb. PMID: 7538620.

1994

Endosomal accumulation of pH indicator dyes delivered as acetoxymethyl esters.Slayman CL, Moussatos VV, Webb WW. J Exp Biol. 1994 Nov. PMID: 7823037.
Metamorphosis of research on ion-coupled metabolite transport.Slayman CL. J Exp Biol. 1994 Nov. PMID: 7823017.
Sorting of the gastric H,K-ATPase in endocrine and epithelial cells.Roush DL, Gottardi CJ, Caplan MJ. Ann N Y Acad Sci. 1994 Sep 15. PMID: 7978870.
Oxygen deprivation activates an ATP-inhibitable K+ channel in substantia nigra neurons.Jiang C, Sigworth FJ, Haddad GG. J Neurosci. 1994 Sep. PMID: 8083755.
Distributed aspects of the response to siphon touch in Aplysia: spread of stimulus information and cross-correlation analysis.Tsau Y, Wu JY, Höpp HP, Cohen LB, Schiminovich D, Falk CX. J Neurosci. 1994 Jul. PMID: 8027769.
Alternatively spliced isoforms of the putative renal Na-K-Cl cotransporter are differentially distributed within the rabbit kidney.Payne JA, Forbush B 3rd. Proc Natl Acad Sci U S A. 1994 May 10. PMID: 7514306.
Molecular cloning and functional expression of the bumetanide-sensitive Na-K-Cl cotransporter.Xu JC, Lytle C, Zhu TT, Payne JA, Benz E Jr, Forbush B 3rd. Proc Natl Acad Sci U S A. 1994 Mar 15. PMID: 8134373.
Consistency in nervous systems: trial-to-trial and animal-to-animal variations in the responses to repeated applications of a sensory stimulus in Aplysia.Wu JY, Tsau Y, Hopp HP, Cohen LB, Tang AC, Falk CX. J Neurosci. 1994 Mar. PMID: 8120632.
Cation effluxes associated with the uptake of TPP+, TPA+, and TPMP+ by Neurospora: evidence for a predominantly electroneutral influx process.Slayman CL, Kuroda H, Ballarin-Denti A. Biochim Biophys Acta. 1994 Feb 23. PMID: 8110821.
Small lipid-soluble cations are not membrane voltage probes for Neurospora or Saccharomyces.Ballarin-Denti A, Slayman CL, Kuroda H. Biochim Biophys Acta. 1994 Feb 23. PMID: 8110820.
The axonal gamma-aminobutyric acid transporter GAT-1 is sorted to the apical membranes of polarized epithelial cells.Pietrini G, Suh YJ, Edelmann L, Rudnick G, Caplan MJ. J Biol Chem. 1994 Feb 11. PMID: 8308038.
Neuronal activity during different behaviors in Aplysia: a distributed organization?Wu JY, Cohen LB, Falk CX. Science. 1994 Feb 11. PMID: 8303300.
Voltage gating of ion channels.Sigworth FJ. Q Rev Biophys. 1994 Feb. PMID: 7520590.

1993

Functional expression and purification of a homomeric human alpha 1 glycine receptor in baculovirus-infected insect cells.Cascio M, Schoppa NE, Grodzicki RL, Sigworth FJ, Fox RO. J Biol Chem. 1993 Oct 15. PMID: 8408073.
Substitution of a hydrophobic residue alters the conformational stability of Shaker K+ channels during gating and assembly.McCormack K, Lin L, Sigworth FJ. Biophys J. 1993 Oct. PMID: 8274662.
Whole-cell currents in single and confluent M-1 mouse cortical collecting duct cells.Korbmacher C, Segal AS, Fejes-Tóth G, Giebisch G, Boulpaep EL. J Gen Physiol. 1993 Oct. PMID: 8270912.
Nonuniform expression of habituation in the activity of distinct classes of neurons in the Aplysia abdominal ganglion.Falk CX, Wu JY, Cohen LB, Tang AC. J Neurosci. 1993 Sep. PMID: 8366360.
Endothelin increases [Ca2+]i in M-1 mouse cortical collecting duct cells by a dual mechanism.Korbmacher C, Boulpaep EL, Giebisch G, Geibel J. Am J Physiol. 1993 Aug. PMID: 8368264.
Molecular requirements for the cell-surface expression of multisubunit ion-transporting ATPases. Identification of protein domains that participate in Na,K-ATPase and H,K-ATPase subunit assembly.Gottardi CJ, Caplan MJ. J Biol Chem. 1993 Jul 5. PMID: 8390991.
An ion-transporting ATPase encodes multiple apical localization signals.Gottardi CJ, Caplan MJ. J Cell Biol. 1993 Apr. PMID: 8385670.
Functional consequences of a Na+ channel mutation causing hyperkalemic periodic paralysis.Cummins TR, Zhou J, Sigworth FJ, Ukomadu C, Stephan M, Ptácek LJ, Agnew WS. Neuron. 1993 Apr. PMID: 8386527.
Gating and conductance in an outward-rectifying K+ channel from the plasma membrane of Saccharomyces cerevisiae.Bertl A, Slayman CL, Gradmann D. J Membr Biol. 1993 Mar. PMID: 8492306.
Fluctuations in ion channel gating currents. Analysis of nonstationary shot noise.Crouzy SC, Sigworth FJ. Biophys J. 1993 Jan. PMID: 8381683.

1992

The Na-K-Cl cotransport protein of shark rectal gland. I. Development of monoclonal antibodies, immunoaffinity purification, and partial biochemical characterization.Lytle C, Xu JC, Biemesderfer D, Haas M, Forbush B 3rd. J Biol Chem. 1992 Dec 15. PMID: 1460038.
The Na-K-Cl cotransport protein of shark rectal gland. II. Regulation by direct phosphorylation.Lytle C, Forbush B 3rd. J Biol Chem. 1992 Dec 15. PMID: 1334094.
Tandem linkage of Shaker K+ channel subunits does not ensure the stoichiometry of expressed channels.McCormack K, Lin L, Iverson LE, Tanouye MA, Sigworth FJ. Biophys J. 1992 Nov. PMID: 1477286.
Complex modulation of cation channels in the tonoplast and plasma membrane of Saccharomyces cerevisiae: single-channel studies.Bertl A, Slayman CL. J Exp Biol. 1992 Nov. PMID: 1283402.
Some remarks on the integrated actions of pumps, cotransporters and channels.Slayman CL. J Exp Biol. 1992 Nov. PMID: 1283401.
Mouse cortical collecting duct cells show nonselective cation channel activity and express a gene related to the cGMP-gated rod photoreceptor channel.Ahmad I, Korbmacher C, Segal AS, Cheung P, Boulpaep EL, Barnstable CJ. Proc Natl Acad Sci U S A. 1992 Nov 1. PMID: 1279673.
Calcium- and voltage-dependent ion channels in Saccharomyces cerevisiae.Bertl A, Gradmann D, Slayman CL. Philos Trans R Soc Lond B Biol Sci. 1992 Oct 29. PMID: 1280839.
Isoforms of the Na,K-ATPase are present in both axons and dendrites of hippocampal neurons in culture.Pietrini G, Matteoli M, Banker G, Caplan MJ. Proc Natl Acad Sci U S A. 1992 Sep 15. PMID: 1326755.
Ion channels in Arabidopsis plasma membrane : transport characteristics and involvement in light-induced voltage changes.Spalding EP, Slayman CL, Goldsmith MH, Gradmann D, Bertl A. Plant Physiol. 1992 May. PMID: 16668890.
muI Na+ channels expressed transiently in human embryonic kidney cells: biochemical and biophysical properties.Ukomadu C, Zhou J, Sigworth FJ, Agnew WS. Neuron. 1992 Apr. PMID: 1314619.