2012
Regulation of glomerulotubular balance. I. Impact of dopamine on flow-dependent transport
Du Z, Yan Q, Wan L, Weinbaum S, Weinstein AM, Wang T. Regulation of glomerulotubular balance. I. Impact of dopamine on flow-dependent transport. American Journal Of Physiology. Renal Physiology 2012, 303: f386-f395. PMID: 22552936, PMCID: PMC3433864, DOI: 10.1152/ajprenal.00531.2011.Peer-Reviewed Original ResearchMeSH Keywords8-Bromo Cyclic Adenosine MonophosphateAlgorithmsAnimalsBenzazepinesBicarbonatesBiological Transport, ActiveChloridesCyclic AMP-Dependent Protein KinasesDopamineDopamine AntagonistsDopamine D2 Receptor AntagonistsFemaleIsoquinolinesKidney GlomerulusKidney TubulesKidney Tubules, ProximalMacrolidesMiceMicrovilliProton-Translocating ATPasesReceptors, Dopamine D1SodiumSulfonamidesSulpirideConceptsNa/H exchanger 3Impact of dopamineMouse proximal tubulesLuminal flowGlomerulotubular balanceCl reabsorptionProximal tubulesNa-K-ATPase activityProximal tubule reabsorptionPKA-mediated mechanismLuminal flow rateLuminal dopamineDA1 receptorsTubule reabsorptionPKA inhibitor H89Exogenous dopamineH-ATPase activityReabsorptive fluxReabsorptionDopamineNHE3 activityInhibitor H89Perfusion conditionsCoordinated modulationFlow stimulation
2007
Role of fluid shear stress in cytoskeleton reorganization of mouse proximal tubule epithelium
Duan Y, Du Z, Yan Q, Weinstein A, Weinbaum S, Wang T. Role of fluid shear stress in cytoskeleton reorganization of mouse proximal tubule epithelium. The FASEB Journal 2007, 21: a915-a915. DOI: 10.1096/fasebj.21.6.a915-a.Peer-Reviewed Original ResearchCytoskeleton reorganizationPeripheral actin networkMPT cellsCell-cell contactZO-1Actin cytoskeletonCellular functionsEpithelial cytoskeletonActin networkJunction-like structuresStress fibersF-actinVinculin expressionCytoskeletonFluid shear stressE-cadherinCollagen substrateMechanical forcesEndothelial cellsCellsH-ATPase activityPT cellsStructural frameworkDifferent responsesStructural components