Increased β-Cell Responsivity Independent of Insulin Sensitivity in Healthy African American Adults
Armiyaw L, Sarcone C, Fosam A, Muniyappa R. Increased β-Cell Responsivity Independent of Insulin Sensitivity in Healthy African American Adults. The Journal Of Clinical Endocrinology & Metabolism 2020, 105: dgaa234. PMID: 32382759, PMCID: PMC7266075, DOI: 10.1210/clinem/dgaa234.Peer-Reviewed Original ResearchConceptsNon-Hispanic whitesTotal β-cell responsivityΒ-cell responsivityPrimary insulin hypersecretionGlucose disposal rateInsulin sensitivityInsulin hypersecretionAfrican AmericansBasal insulin secretion rateGlucose responsivityIntravenous glucose tolerance testGlucose tolerance testHyperinsulinemic euglycemic glucose clamp techniqueC-peptide secretionGlucose clamp techniqueInsulin secretion rateNondiabetic African AmericansΒ-cell functionAfrican American adultsInsulin resistanceTolerance testNHW subjectsC-peptideInsulin secretionSignificant ethnic differencesOR08-05 Sex and Ethnic Differences in Advanced Lipoprotein Profiles in South Asians, African-Americans, and Caucasians
Sarcone C, Fosam A, Armiyaw A, Grewal S, Bansal R, Rabel A, Muniyappa R. OR08-05 Sex and Ethnic Differences in Advanced Lipoprotein Profiles in South Asians, African-Americans, and Caucasians. Journal Of The Endocrine Society 2020, 4: or08-05. PMCID: PMC7208063, DOI: 10.1210/jendso/bvaa046.1428.Peer-Reviewed Original ResearchLow-density lipoprotein particlesHDL particle numberTriglyceride-rich lipoprotein particlesLipoprotein profileHigh-density lipoprotein particlesSA menLipoprotein particlesInsulin resistanceInsulin sensitivityCA menCardiovascular diseaseSouth AsiansAfrican AmericansEthnic differencesCholesteryl ester transfer protein activityIntravenous glucose tolerance testAdvanced lipoprotein profileStandard lipid panelLDL particle numberAtherogenic lipoprotein profileGlucose tolerance testCross-sectional studyApoA-I levelsHDL particle sizeFat-free massSAT-651 Ethnic Differences in the Relationship Between Uric Acid Clearance and Insulin Sensitivity
Armiyaw A, Fosam A, Sarcone C, Aradhya A, Walter M, Rabel A, Muniyappa R. SAT-651 Ethnic Differences in the Relationship Between Uric Acid Clearance and Insulin Sensitivity. Journal Of The Endocrine Society 2020, 4: sat-651. PMCID: PMC7209748, DOI: 10.1210/jendso/bvaa046.1820.Peer-Reviewed Original ResearchIntravenous glucose tolerance testInsulin-resistant statesFractional excretionInsulin sensitivityUA clearanceUric acidAfrican AmericansUA productionGlucose tolerance testUric acid clearanceSpot urine samplesType 2 diabetesUrinary uric acidCross-sectional studyEthnic differencesPlasma uric acidPercent body fatPathogenesis of hyperuricemiaUric acid productionAcid clearanceCreatinine ratioDiastolic BPHigher BMIUA levelsTolerance test