2023
Cytokinopathy with aberrant cytotoxic lymphocytes and profibrotic myeloid response in SARS-CoV-2 mRNA vaccine–associated myocarditis
Barmada A, Klein J, Ramaswamy A, Brodsky N, Jaycox J, Sheikha H, Jones K, Habet V, Campbell M, Sumida T, Kontorovich A, Bogunovic D, Oliveira C, Steele J, Hall E, Pena-Hernandez M, Monteiro V, Lucas C, Ring A, Omer S, Iwasaki A, Yildirim I, Lucas C. Cytokinopathy with aberrant cytotoxic lymphocytes and profibrotic myeloid response in SARS-CoV-2 mRNA vaccine–associated myocarditis. Science Immunology 2023, 8: eadh3455-eadh3455. PMID: 37146127, PMCID: PMC10468758, DOI: 10.1126/sciimmunol.adh3455.Peer-Reviewed Original ResearchConceptsMRNA vaccinesSARS-CoV-2 mRNA vaccinesSARS-CoV-2 mRNA vaccinationC-reactive protein levelsB-type natriuretic peptidePeripheral blood mononuclear cellsCardiac tissue inflammationDeep immune profilingSerum soluble CD163Vaccine-associated myocarditisCohort of patientsBlood mononuclear cellsCytotoxic T cellsLate gadolinium enhancementHypersensitivity myocarditisElevated troponinMRNA vaccinationImaging abnormalitiesNK cellsImmune profilingKiller cellsMyeloid responseNatriuretic peptideHumoral mechanismsInflammatory cytokines
2022
Pediatric COVID-19 Health Disparities and Vaccine Equity
Oliveira CR, Feemster KA, Ulloa ER. Pediatric COVID-19 Health Disparities and Vaccine Equity. Journal Of The Pediatric Infectious Diseases Society 2022, 11: s141-s147. PMID: 36124679, PMCID: PMC9494479, DOI: 10.1093/jpids/piac091.Commentaries, Editorials and LettersConceptsVaccine equityHealth disparitiesLong-term complicationsCOVID-19 health disparitiesCOVID-19 infectionCOVID-19 vaccineMild illnessPediatric populationVaccine uptakePoor outcomeSevere diseaseVaccine inequityMost childrenEthnic minority groupsChildrenSame childrenInfectionLow-income homesDisparitiesComplicationsGroupVaccineIllnessDiseaseSeverity