Novel Insights into Acid-Sensing Ion Channels: Implications for Degenerative Diseases.
Zhou R, Wu X, Wang Z, Xie Y, Ge J, Chen F. Novel Insights into Acid-Sensing Ion Channels: Implications for Degenerative Diseases. Aging And Disease 2015, 7: 491-501. PMID: 27493834, PMCID: PMC4963192, DOI: 10.14336/ad.2015.1213.Peer-Reviewed Original ResearchAcid-sensing ion channelsDegenerative diseasesActivation of ASICsEffective treatment optionIon channelsLigand-gated ion channelsIntervertebral disc degenerationMultiple sclerosisTreatment optionsParkinson's diseaseTherapeutic targetDegenerative disordersDisc degenerationProgressive deteriorationDiseaseAberrant activationHuntington's diseaseOlder adultsCritical roleCell apoptosisPathological conditionsOrgan degenerationDegenerationPotential utilityActivation