2024
Cefazolin Alone Versus Cefazolin with Tobramycin or Gentamicin as Intraoperative Antibiotic Prophylaxis for Single-Level Posterior Lumbar Fusion
Dhodapkar M, Jeong S, Halperin S, Rubio D, Li M, Grauer J. Cefazolin Alone Versus Cefazolin with Tobramycin or Gentamicin as Intraoperative Antibiotic Prophylaxis for Single-Level Posterior Lumbar Fusion. JAAOS Global Research And Reviews 2024, 8: e24.00082. PMCID: PMC11068128, DOI: 10.5435/jaaosglobal-d-24-00082.Peer-Reviewed Original ResearchSingle-level posterior lumbar fusionPosterior lumbar fusionSurgical site infectionElixhauser Comorbidity IndexLumbar fusionAntibiotic prophylaxisAdverse outcomesAntibiotic prophylaxis regimenAntibiotic prophylaxis regimensIntraoperative antibiotic prophylaxisRevision ratePerioperative antibiotic prophylaxisPostoperative adverse outcomesPosterior lumbar fusion patientsMultivariate logistic regressionProphylaxis regimensProphylaxis regimenPatient ageSite infectionUnivariate analysisCefazolinComorbidity indexMultivariate analysisAntibiotic subgroupsTraumatic diagnosesTotal shoulder arthroplasty in patients with Factor V Leiden
Zehner K, Sanchez J, Dhodapkar M, Modrak M, Luo X, Grauer J. Total shoulder arthroplasty in patients with Factor V Leiden. Journal Of Shoulder And Elbow Surgery 2024 PMID: 38479723, DOI: 10.1016/j.jse.2024.01.041.Peer-Reviewed Original ResearchFactor V LeidenVenous thromboembolismAdverse eventsV LeidenTSA patientsRevision rateProphylactic agentFactor V Leiden patientsVTE prophylactic agentOdds ratioRisk of venous thromboembolismEffective treatment optionOdds of bleeding complicationsDeep vein thrombosisMultivariate logistic regressionEnd-stage glenohumeral osteoarthritisTotal shoulder arthroplastyInherited thrombophiliaBleeding complicationsElixhauser Comorbidity IndexLonger-term outcomesPulmonary embolismProthrombotic stateVein thrombosisAdult patients
2023
Patients With Cystic Fibrosis Undergoing Total Hip and Total Knee Arthroplasty Are at Increased Risk for Perioperative Complications
Halperin S, Dhodapkar M, Radford Z, Kaszuba S, Rubin L, Grauer J. Patients With Cystic Fibrosis Undergoing Total Hip and Total Knee Arthroplasty Are at Increased Risk for Perioperative Complications. Journal Of The American Academy Of Orthopaedic Surgeons 2023, 32: 309-315. PMID: 38165956, DOI: 10.5435/jaaos-d-23-00783.Peer-Reviewed Original ResearchTotal knee arthroplastyTotal hip arthroplastyUrinary tract infectionPostoperative eventsCystic fibrosisPerioperative outcomesAdverse eventsTract infectionsPleural effusionKnee arthroplastyControl subjectsRevision rateAcute kidney injuryElixhauser Comorbidity IndexRisk of surgeryMultivariable logistic regressionComorbidity indexKidney injuryPerioperative complicationsRespiratory failureTKA patientsCardiac eventsPearlDiver databaseImplant survivalTotal hipPatients With Down Syndrome and Total Hip and Total Knee Arthroplasty: Outcome Measures Show Increased Risk of Perioperative Complications
Halperin S, Dhodapkar M, Radford Z, Frumberg D, Rubin L, Grauer J. Patients With Down Syndrome and Total Hip and Total Knee Arthroplasty: Outcome Measures Show Increased Risk of Perioperative Complications. JAAOS Global Research And Reviews 2023, 7: e23.00108. PMID: 38054749, PMCID: PMC10697628, DOI: 10.5435/jaaosglobal-d-23-00108.Peer-Reviewed Original ResearchConceptsTotal knee arthroplastyTotal hip arthroplastyAcute kidney injuryUrinary tract infectionAdverse eventsDown syndromePostoperative eventsKnee arthroplastyRevision ratePerioperative risk assessmentMinor adverse eventsOutcomes of patientsMultivariable logistic regressionTotal joint arthroplastyPatient/family counselingKidney injuryPerioperative complicationsTKA patientsAdult patientsTract infectionsDS patientsIncreased riskTotal hipCare pathwayJoint arthroplastyTotal Hip Arthroplasty in Patients Who Have Marfan Syndrome: Adverse Events and 5-Year Revision Rates
Day W, Jayaram R, Rubin L, Grauer J. Total Hip Arthroplasty in Patients Who Have Marfan Syndrome: Adverse Events and 5-Year Revision Rates. The Journal Of Arthroplasty 2023, 39: s275-s278. PMID: 37952742, DOI: 10.1016/j.arth.2023.10.052.Peer-Reviewed Original ResearchTotal hip arthroplastyAdverse eventsMarfan syndromeMultivariable analysisHip arthroplastyUnderwent total hip arthroplastyPostoperative adverse eventsVenous thromboembolic eventsPerioperative care pathwaysUrinary tract infectionConnective tissue diseaseLog-rank testRare disease populationComorbidity indexThromboembolic eventsCardiac eventsPostoperative courseTract infectionsAdult patientsTissue diseaseHip pathologyRevision rateCare pathwayDisease populationGreater oddsSingle-level Anterior Cervical Discectomy and Fusion Results in Lower Five-year Revisions than Posterior Cervical Foraminotomy in a Large National Cohort
Jayaram R, Joo P, Gouzoulis M, Ratnasamy P, Caruana D, Grauer J. Single-level Anterior Cervical Discectomy and Fusion Results in Lower Five-year Revisions than Posterior Cervical Foraminotomy in a Large National Cohort. Spine 2023, 48: 1266-1271. PMID: 37339256, DOI: 10.1097/brs.0000000000004754.Peer-Reviewed Original ResearchConceptsPosterior cervical foraminotomySingle-level ACDFSingle-level anterior cervical discectomyPerioperative adverse eventsAnterior cervical discectomyAdverse eventsCervical foraminotomyCervical discectomyRevision rateOdds ratioShort-term adverse eventsSimilar short-term outcomesKaplan-Meier survival analysisRetrospective cohort studySerious adverse eventsCervical disc diseaseFive-year ratesSurgical site infectionShort-term outcomesMultivariable logistic regressionLarge national cohortCumulative revision rateCervical reoperationPCF cohortCohort studyComparative Success of Repair Versus Reconstruction for Knee Extra-articular Ligament Injuries
Kahan J, Burroughs P, Mclaughlin W, Schneble C, Moran J, Joo P, Modrak M, Richter D, Wascher D, Treme G, Schenck R, Grauer J, Medvecky M. Comparative Success of Repair Versus Reconstruction for Knee Extra-articular Ligament Injuries. Orthopaedic Journal Of Sports Medicine 2023, 11: 23259671221143539. PMID: 36743731, PMCID: PMC9893380, DOI: 10.1177/23259671221143539.Peer-Reviewed Original ResearchCruciate ligament reconstructionLigament injurySurgical repairLigament reconstructionRevision surgeryKnee injuriesExtra-articular ligament reconstructionSubsequent surgery ratesOptimal surgical treatmentKnee ligament injuriesHigher revision rateLevel of evidenceLarge national databaseHigh rateLigament proceduresReconstruction cohortRepair cohortCohort studySurgical treatmentSurgery ratesPatient cohortSecondary proceduresRevision rateLigamentous reconstructionSurgical technique
2022
Hidradenitis Suppurativa Leads to Increased Risk of Wound-Related Complications following Total Joint Arthroplasty
Gouzoulis MJ, Kammien AJ, Caruana DL, Wiznia DH, Grauer JN. Hidradenitis Suppurativa Leads to Increased Risk of Wound-Related Complications following Total Joint Arthroplasty. Arthroplasty Today 2022, 16: 169-174. PMID: 35789782, PMCID: PMC9249970, DOI: 10.1016/j.artd.2022.05.013.Peer-Reviewed Original ResearchTotal knee arthroplastyTotal hip arthroplastyAdverse eventsHS patientsImplant survivalSkin lesionsKaplan-Meier survival curvesNon-HS patientsSurgical site infectionElixhauser Comorbidity IndexInflammatory skin lesionsSpecific adverse eventsLog-rank testPotential risk factorsTotal joint arthroplastyWound-related issuesRisk of woundComorbidity indexAdult patientsSite infectionDegenerative etiologyWound dehiscenceKnee arthroplastyRevision rateRisk factors