2024
Improved total shoulder arthroplasty outcomes associated with semaglutide utilization in patients with type II diabetes: A promising new addition to preoperative optimization
Seddio A, Wilhelm C, Gouzoulis M, Islam W, Vasudevan R, Halperin S, Rubin L, Medvecky M, Donohue K, Grauer J. Improved total shoulder arthroplasty outcomes associated with semaglutide utilization in patients with type II diabetes: A promising new addition to preoperative optimization. JSES International 2024 DOI: 10.1016/j.jseint.2024.10.006.Peer-Reviewed Original ResearchTotal shoulder arthroplastyBody mass indexT2DM patientsElixhauser Comorbidity IndexMultivariate analysisOdds of surgical site infectionUrinary tract infectionSurgical site infectionAcute kidney injuryType II diabetes mellitusII diabetes mellitusTract infectionsSite infectionClinical benefitPreoperative optimizationCardiac eventsKidney injuryVenous thromboembolismMetformin useAdverse eventsManagement of type II diabetes mellitusMass indexDiabetes mellitusType II diabetesAdverse outcomesRisk Factors for Perioperative Nerve Injury Related to Total Hip Arthroplasty
Jayaram R, Day W, Gouzoulis M, Zhu J, Grauer J, Rubin L. Risk Factors for Perioperative Nerve Injury Related to Total Hip Arthroplasty. Arthroplasty Today 2024, 28: 101440. PMID: 39139361, PMCID: PMC11320433, DOI: 10.1016/j.artd.2024.101440.Peer-Reviewed Original ResearchBody mass indexNerve injuryElixhauser Comorbidity IndexRisk factorsMultivariate analysisOdds ratioRisk of nerve injuryTotal hip arthroplastyRevision proceduresObese BMI statusUnderweight body mass indexDecreased odds ratioPatient ageSurgery typeRisk stratificationAdverse eventsBMI statusMass indexFemale sexAdverse outcomesComorbidity indexDecreased riskPatient counselingHip arthroplastyNerve
2023
Risk of Contralateral Hip Fracture Following Initial Hip Fracture Among Geriatric Fragility Fracture Patients
Ratnasamy P, Rudisill K, Oghenesume O, Riedel M, Grauer J. Risk of Contralateral Hip Fracture Following Initial Hip Fracture Among Geriatric Fragility Fracture Patients. JAAOS Global Research And Reviews 2023, 7: e23.00001. PMID: 37428152, PMCID: PMC10332831, DOI: 10.5435/jaaosglobal-d-23-00001.Peer-Reviewed Original ResearchConceptsContralateral hip fractureInitial hip fractureKaplan-Meier survival analysisGeriatric hip fracturesHip fractureSurvival analysisFragility fracture patientsIndex hip fractureHip fracture fixationKaplan-Meier analysisBody mass indexMultivariate logistic regressionFracture patientsContralateral fractureIndependent predictorsGeriatric patientsHigh morbidityMass indexPatient mortalityFemale sexNational cohortRisk factorsFracture fixationMultivariate analysisLogistic regressionPostoperative Antibiotics Following Reduction Mammaplasty Does Not Reduce Rates of Surgical Site Infection
Mookerjee V, Kammien A, Prassinos A, Grauer J, Butler P. Postoperative Antibiotics Following Reduction Mammaplasty Does Not Reduce Rates of Surgical Site Infection. Aesthetic Surgery Journal 2023, 43: np494-np499. PMID: 36788713, DOI: 10.1093/asj/sjad030.Peer-Reviewed Original ResearchConceptsRate of SSISurgical site infectionBody mass indexReduction mammaplasty patientsPostoperative antibioticsPerioperative antibioticsED visitsSSI ratesSite infectionObese populationReduction mammaplastyPostoperative antibiotic useElixhauser Comorbidity IndexEmergency department visitsSubgroup of patientsPostoperative prescriptionComorbidity indexObese patientsPostoperative courseDepartment visitsMass indexAntibiotic utilizationSubgroup analysisAntibiotic useHigh risk
2022
Incidence, Timing, and Predictors of Hip Dislocation After Primary Total Hip Arthroplasty for Osteoarthritis
Gillinov SM, Joo PY, Zhu JR, Moran J, Rubin LE, Grauer JN. Incidence, Timing, and Predictors of Hip Dislocation After Primary Total Hip Arthroplasty for Osteoarthritis. Journal Of The American Academy Of Orthopaedic Surgeons 2022, 30: 1047-1053. PMID: 35947825, PMCID: PMC9588560, DOI: 10.5435/jaaos-d-22-00150.Peer-Reviewed Original ResearchConceptsPrimary total hip arthroplastyTotal hip arthroplastyElixhauser Comorbidity IndexBody mass indexComorbidity indexMass indexHip dislocationRevision surgeryRisk factorsHip arthroplastyIndex total hip arthroplastyHigher Elixhauser comorbidity indexPrimary THA patientsFirst-time dislocationCumulative incidenceMost patientsPostoperative dataTHA patientsRecurrent episodesControl subjectsFemale sexLarge cohortPatientsMultivariate analysisYounger ageJump in Elective Total Hip and Knee Arthroplasty Numbers at Age 65 Years: Evidence for Moral Hazard?
Rankin KA, Freedman IG, Moore HG, Halperin SJ, Rubin LE, Grauer JN. Jump in Elective Total Hip and Knee Arthroplasty Numbers at Age 65 Years: Evidence for Moral Hazard? JAAOS Global Research And Reviews 2022, 6: e22.00035. PMID: 35315795, PMCID: PMC8942773, DOI: 10.5435/jaaosglobal-d-22-00035.Peer-Reviewed Original ResearchConceptsTotal knee arthroplastyTotal hip arthroplastyAge 65 yearsNational Surgical Quality Improvement Program databaseIncidence of TKAElective total knee arthroplastyQuality Improvement Program databaseLower body mass indexElective total hipPostoperative adverse eventsPreoperative American SocietyImprovement Program databaseLower functional statusBody mass indexNon-Hispanic whitesNumber of proceduresAnesthesiologists classPreoperative characteristicsOlder patientsAdverse eventsTHA patientsMass indexTotal hipFunctional statusKnee arthroplasty
2020
Underweight patients are an often under looked “At risk” population after undergoing posterior cervical spine surgery
Ottesen TD, Bagi PS, Malpani R, Galivanche AR, Varthi AG, Grauer JN. Underweight patients are an often under looked “At risk” population after undergoing posterior cervical spine surgery. North American Spine Society Journal (NASSJ) 2020, 5: 100041. PMID: 35141608, PMCID: PMC8820029, DOI: 10.1016/j.xnsj.2020.100041.Peer-Reviewed Original ResearchBody mass indexPosterior cervical spine surgeryCervical spine surgeryAdverse eventsBMI categoriesBMI spectrumSpine surgeryNational Surgical Quality Improvement Program databaseRisk-adjusted multivariate regressionsQuality Improvement Program databaseHigher body mass indexLower body mass indexOutcomes of patientsImprovement Program databaseNormal-weight subjectsCategory of patientsSpine surgery outcomesUnderweight patientsPatient demographicsBMI groupsMass indexAdverse outcomesSurgery outcomesProgram databaseInclusion criteria
2018
Missing data treatments matter: an analysis of multiple imputation for anterior cervical discectomy and fusion procedures
Ondeck NT, Fu MC, Skrip LA, McLynn RP, Cui JJ, Basques BA, Albert TJ, Grauer JN. Missing data treatments matter: an analysis of multiple imputation for anterior cervical discectomy and fusion procedures. The Spine Journal 2018, 18: 2009-2017. PMID: 29649614, DOI: 10.1016/j.spinee.2018.04.001.Peer-Reviewed Original ResearchConceptsSevere adverse eventsNational Surgical Quality Improvement ProgramAnterior cervical discectomyAdverse eventsPreoperative anemiaPreoperative hypoalbuminemiaPreoperative albuminCervical discectomyHospital readmissionAdverse outcomesComplete case analysisSurgical Quality Improvement ProgramAdverse outcome variablesOne-level ACDFPreoperative laboratory valuesBody mass indexFusion proceduresMultiple imputationLogistic regression analysisQuality Improvement ProgramPreoperative hematocritPostoperative outcomesRetrospective reviewMass indexLaboratory valuesInaccuracies in ICD Coding for Obesity Would Be Expected to Bias Administrative Database Spine Studies Toward Overestimating the Impact of Obesity on Perioperative Adverse Outcomes
McLynn RP, Geddes BJ, Cui JJ, Ondeck NT, Bovonratwet P, Shultz BN, Grauer JN. Inaccuracies in ICD Coding for Obesity Would Be Expected to Bias Administrative Database Spine Studies Toward Overestimating the Impact of Obesity on Perioperative Adverse Outcomes. Spine 2018, 43: 526-532. PMID: 28767639, DOI: 10.1097/brs.0000000000002356.Peer-Reviewed Original ResearchConceptsBody mass indexMajor adverse eventsAdverse eventsICD codesVenous thromboembolismElective posterior lumbar fusionGreater body mass indexPerioperative adverse outcomesPostoperative adverse eventsRetrospective cohort studyAssociation of obesityImpact of obesityLength of stayPosterior lumbar fusionLarge academic hospitalSpine surgery literaturePostoperative complicationsPostoperative factorsCohort studyMass indexAdverse outcomesLumbar fusionAcademic hospitalBACKGROUND DATASpine studies
2017
Definitional Differences of ‘Outpatient’ Versus ‘Inpatient’ THA and TKA Can Affect Study Outcomes
Bovonratwet P, Webb ML, Ondeck NT, Lukasiewicz AM, Cui JJ, McLynn RP, Grauer JN. Definitional Differences of ‘Outpatient’ Versus ‘Inpatient’ THA and TKA Can Affect Study Outcomes. Clinical Orthopaedics And Related Research® 2017, 475: 2917-2925. PMID: 28083753, PMCID: PMC5670045, DOI: 10.1007/s11999-017-5236-6.Peer-Reviewed Original ResearchMeSH KeywordsAmbulatory Surgical ProceduresArthroplasty, Replacement, HipArthroplasty, Replacement, KneeData MiningDatabases, FactualFemaleHumansInpatientsKaplan-Meier EstimateLength of StayMaleMultivariate AnalysisPatient AdmissionProcess Assessment, Health CarePropensity ScoreRetrospective StudiesRisk FactorsTerminology as TopicTime FactorsTreatment OutcomeUnited StatesConceptsNational Surgical Quality Improvement ProgramHospital LOSAdverse eventsNSQIP databaseRisk factorsSurgical Quality Improvement ProgramLength of hospitalSerious adverse eventsBody mass indexTotal joint arthroplastyPotential confounding factorsLarge national databaseQuality Improvement ProgramOutpatient THAPostoperative complicationsTKA cohortSmoking statusMass indexFunctional statusOutpatient procedureJoint arthroplastyActual LOSTherapeutic studiesOutpatientsPatientsDiscriminative Ability of Elixhauser's Comorbidity Measure is Superior to Other Comorbidity Scores for Inpatient Adverse Outcomes After Total Hip Arthroplasty
Ondeck NT, Bohl DD, Bovonratwet P, McLynn RP, Cui JJ, Grauer JN. Discriminative Ability of Elixhauser's Comorbidity Measure is Superior to Other Comorbidity Scores for Inpatient Adverse Outcomes After Total Hip Arthroplasty. The Journal Of Arthroplasty 2017, 33: 250-257. PMID: 28927567, DOI: 10.1016/j.arth.2017.08.032.Peer-Reviewed Original ResearchConceptsElixhauser comorbidity measuresCharlson Comorbidity IndexTotal hip arthroplastyAdverse outcomesComorbidity measuresComorbidity indexHip arthroplastyDiscriminative abilityBody mass indexNational Inpatient SampleLength of stayAdverse patient outcomesComorbidity scoreHospital stayPerioperative courseFrailty indexMass indexComplication measuresPatient's probabilityInpatient SamplePatient outcomesDemographic factors ageHigh riskOptimize outcomesAdmission center
2015
Postoperative Length of Stay and 30-Day Readmission After Geriatric Hip Fracture
Basques BA, Bohl DD, Golinvaux NS, Leslie MP, Baumgaertner MR, Grauer JN. Postoperative Length of Stay and 30-Day Readmission After Geriatric Hip Fracture. Journal Of Orthopaedic Trauma 2015, 29: e115-e120. PMID: 25210835, DOI: 10.1097/bot.0000000000000222.Peer-Reviewed Original ResearchConceptsGeriatric hip fracturesBody mass indexPostoperative LOSHip fractureRisk factorsPostoperative lengthMass indexSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseMultivariate analysisQuality Improvement Program databaseAverage postoperative LOSDependent functional statusNon-general anesthesiaPrognostic Level IIHip fracture surgeryPercent of patientsHip fracture patientsHip fracture repairImprovement Program databaseSignificant risk factorsAnesthesiologists classAnesthesia typeFracture patientsPostoperative dayComparison of 368 Patients Undergoing Surgery for Lumbar Degenerative Spondylolisthesis From the SPORT Trial With 955 From the NSQIP Database
Golinvaux NS, Basques BA, Bohl DD, Yacob A, Grauer JN. Comparison of 368 Patients Undergoing Surgery for Lumbar Degenerative Spondylolisthesis From the SPORT Trial With 955 From the NSQIP Database. Spine 2015, 40: 342-348. PMID: 25757036, DOI: 10.1097/brs.0000000000000747.Peer-Reviewed Original ResearchConceptsSpine Patient Outcomes Research TrialPerioperative factorsPerioperative outcomesNSQIP databaseDegenerative spondylolisthesisSurgical proceduresNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseAverage body mass indexImprovement Program databaseAverage operative timeLumbar degenerative spondylolisthesisBody mass indexPostoperative mortalityPostoperative transfusionComplication rateRetrospective cohortSurgical patientsNonsurgical treatmentAnalysis of demographicsMass indexOperative timeSmoking statusLumbar pathologyWound infection
2014
Patient Characteristics Associated With Increased Postoperative Length of Stay and Readmission After Elective Laminectomy for Lumbar Spinal Stenosis
Basques BA, Varthi AG, Golinvaux NS, Bohl DD, Grauer JN. Patient Characteristics Associated With Increased Postoperative Length of Stay and Readmission After Elective Laminectomy for Lumbar Spinal Stenosis. Spine 2014, 39: 833-840. PMID: 24525996, PMCID: PMC4006290, DOI: 10.1097/brs.0000000000000276.Peer-Reviewed Original ResearchConceptsLumbar spinal stenosisAnesthesiologists class 3Independent risk factorBody mass indexSpinal stenosisRisk factorsElective laminectomyPostoperative lengthPatient characteristicsReadmission analysisMass indexAmerican CollegeNational Surgical Quality Improvement Program databaseSurgeons National Surgical Quality Improvement Program databaseSurgeons National Surgical Quality Improvement ProgramNational Surgical Quality Improvement ProgramSurgical site-related infectionsQuality Improvement Program databaseSurgical Quality Improvement ProgramAverage postoperative LOSImprovement Program databaseAmerican SocietyQuality Improvement ProgramClass 3Preoperative hematocritLimitations of administrative databases in spine research: a study in obesity
Golinvaux NS, Bohl DD, Basques BA, Fu MC, Gardner EC, Grauer JN. Limitations of administrative databases in spine research: a study in obesity. The Spine Journal 2014, 14: 2923-2928. PMID: 24780248, DOI: 10.1016/j.spinee.2014.04.025.Peer-Reviewed Original ResearchConceptsICD-9 codesBody mass indexNational inpatient databaseProportion of patientsLarge academic medical centerNinth Revision codesCross-sectional studySurgery researchSpine surgery researchAcademic medical centerOnly comorbidityPediatric patientsMass indexInpatient DatabaseRevision codesDiagnosis codesMedical recordsAdministrative databasesSpine surgeryMedical CenterDatabase studyInternational ClassificationPatientsObesityLarger sample size
2013
Anterior and posterior cervical fusion in patients with high body mass index are not associated with greater complications
Buerba RA, Fu MC, Grauer JN. Anterior and posterior cervical fusion in patients with high body mass index are not associated with greater complications. The Spine Journal 2013, 14: 1643-1653. PMID: 24388595, DOI: 10.1016/j.spinee.2013.09.054.Peer-Reviewed Original ResearchConceptsBody mass indexPosterior cervical fusionHigher body mass indexEffect of obesityCervical fusionDeep vein thrombosisComplication rateMass indexPosterior fusionUnivariate analysisBasis of BMIExact testSurgeons National Surgical Quality Improvement ProgramMultivariate analysisNational Surgical Quality Improvement ProgramObese class III patientsSurgical Quality Improvement ProgramTotal operating room timeACS-NSQIP databaseCurrent Procedural Terminology codesRetrospective cohort analysisCervical fusion surgeryPrimary outcome measureSpinal fusion outcomesLength of stayAnterior and Posterior Cervical Fusion in Patients with High Body Mass Index Appear Safe Overall: An Analysis of 4,071 Patients in the ACS-NSQIP Database
Buerba R, Fu M, Gruskay J, Grauer J. Anterior and Posterior Cervical Fusion in Patients with High Body Mass Index Appear Safe Overall: An Analysis of 4,071 Patients in the ACS-NSQIP Database. The Spine Journal 2013, 13: s150. DOI: 10.1016/j.spinee.2013.07.382.Peer-Reviewed Original Research
2012
Effect of age on partial weight-bearing training.
Hustedt JW, Blizzard DJ, Baumgaertner MR, Leslie MP, Grauer JN. Effect of age on partial weight-bearing training. Orthopedics 2012, 35: e1061-7. PMID: 22784901, DOI: 10.3928/01477447-20120621-23.Peer-Reviewed Original ResearchConceptsPartial weight-bearing instructionsWeight-bearing instructionsWeight-bearing trainingWeight bearingOrthopedic patientsEffect of ageBathroom scaleHigher body mass indexBody mass indexBiofeedback devicePostoperative extremityWorse complianceMale sexMass indexAdvanced ageAsymptomatic participantsMixed model analysisAge groupsPatientsVerbal instructionsHeavy weight bearingBiofeedback trainingSignificant predictorsSuperior complianceAge
2008
Quantifying the Effects of Degeneration and Other Patient Factors on Lumbar Segmental Range of Motion Using Multivariate Analysis
Bible JE, Simpson AK, Emerson JW, Biswas D, Grauer JN. Quantifying the Effects of Degeneration and Other Patient Factors on Lumbar Segmental Range of Motion Using Multivariate Analysis. Spine 2008, 33: 1793-1799. PMID: 18628713, DOI: 10.1097/brs.0b013e31817b8f3a.Peer-Reviewed Original ResearchConceptsBody mass indexLumbar ROMKellgren scoreMultivariate analysisSignificant negative associationSegmental ROML5-S1L4-L5Segmental rangeL3-L4L2-L3Negative associationMultivariate regression analysisPatient factorsRetrospective reviewMass indexClinical variablesUnivariate analysisBACKGROUND DATAFlexion/extensionSignificant associationL1-S1Role of ageInterobserver reliabilityDegeneration