2023
Timing of Adverse Events Within 90 Days of Hip Fracture Surgery: A Database Study
Kammien A, Ratnasamy P, Caruana D, Grauer J. Timing of Adverse Events Within 90 Days of Hip Fracture Surgery: A Database Study. Journal Of The American Academy Of Orthopaedic Surgeons 2023, 31: 245-251. PMID: 36821080, DOI: 10.5435/jaaos-d-22-00368.Peer-Reviewed Original ResearchConceptsHip fracture surgeryTime of diagnosisAdverse eventsFracture surgeryDay 31Hip fracture surgery patientsElixhauser comorbidity index scoreAcute kidney injuryCommon adverse eventsComorbidity Index scorePatients 65 yearsPostoperative day 0Surgical site infectionUrinary tract infectionPostoperative day 30Specific adverse eventsKidney injuryCardiac eventsSurgery patientsTract infectionsVenous thromboembolismSite infectionPatient counselingNotable morbidityDatabase study
2022
Comparing Venous Thromboembolism Prophylactic Agents After Hip Fracture Surgery: A National Database Study
Joo P, Modrak M, Park N, Brand J, Rubin L, Grauer J, Bernstein J. Comparing Venous Thromboembolism Prophylactic Agents After Hip Fracture Surgery: A National Database Study. JAAOS Global Research And Reviews 2022, 6: e22.00228. PMID: 36732301, PMCID: PMC9746777, DOI: 10.5435/jaaosglobal-d-22-00228.Peer-Reviewed Original ResearchConceptsHip fracture surgeryFracture surgeryAdverse eventsOdds ratioProphylactic agentGreater oddsAnticoagulant-naïve patientsDifferent anticoagulant agentsVenous thromboembolism chemoprophylaxisVTE prophylactic agentNational database studyDistal femoral fracturesCoumadin groupLower transfusionVTE prophylaxisVTE ratesPatient characteristicsComorbidity profilesFemoral fracturesChemoprophylactic agentAnticoagulant agentsCoumadinDatabase studyLower oddsPatientsNinety-Day Emergency Department Visits After Ankle Fracture Surgery
Kammien A, Ratnasamy P, Joo P, Grauer J. Ninety-Day Emergency Department Visits After Ankle Fracture Surgery. Journal Of The American Academy Of Orthopaedic Surgeons 2022, 31: e51-e57. PMID: 36548157, DOI: 10.5435/jaaos-d-22-00484.Peer-Reviewed Original ResearchConceptsAnkle fracture surgeryElixhauser comorbidity index scoreComorbidity Index scoreED visitsED utilizationFracture surgeryPostoperative weekRisk factorsSurgical siteIndex scoreIncidence of readmissionEmergency department visitsDay of surgeryMultivariate logistic regressionORIF patientsPatient ageAnkle fracturesDepartment visitsOpen reductionConcomitant fracturesMedicaid insuranceEntire cohortEmergency departmentInternal fixationCare pathway
2021
COVID-positive ankle fracture patients are at increased odds of perioperative surgical complications following open reduction internal fixation surgery
Mercier MR, Galivanche AR, Brand JP, Pathak N, Medvecky MJ, Varthi AG, Rubin LE, Grauer JN. COVID-positive ankle fracture patients are at increased odds of perioperative surgical complications following open reduction internal fixation surgery. PLOS ONE 2021, 16: e0262115. PMID: 34972190, PMCID: PMC8719674, DOI: 10.1371/journal.pone.0262115.Peer-Reviewed Original ResearchConceptsCOVID-positive patientsAnkle fracture surgeryPerioperative adverse eventsAdverse eventsAnkle fracture patientsFracture surgeryFracture patientsOperative interventionAnkle fracturesPropensity matchingCOVID statusOpen reduction internal fixation surgeryPerioperative adverse outcomesPerioperative surgical complicationsMinor adverse eventsPostoperative adverse eventsSerious adverse eventsChronic kidney diseaseCOVID-19 Research DatabaseLong-term outcomesInternal fixation surgeryBasis of agePropensity-score matchingPostoperative complicationsNegative patientsClinical Characteristics and Perioperative Complication Profiles of COVID-19–Positive Patients Undergoing Hip Fracture Surgery
Galivanche AR, Mercier MR, Schneble CA, Brand J, Pathak N, Varthi AG, Rubin LE, Grauer JN. Clinical Characteristics and Perioperative Complication Profiles of COVID-19–Positive Patients Undergoing Hip Fracture Surgery. JAAOS Global Research And Reviews 2021, 5: e21.00104. PMID: 34653097, PMCID: PMC8522872, DOI: 10.5435/jaaosglobal-d-21-00104.Peer-Reviewed Original ResearchConceptsHip fracture surgeryCOVID-19 positive patientsMinor adverse eventsAdverse eventsCOVID-19 positivityFracture surgeryHigh incidenceCOVID-19 positive groupCOVID-19 positive statusCOVID-19-negative groupGeriatric hip fracture surgeryPerioperative complication profilePostoperative adverse eventsHip fracture patientsSerious adverse eventsPatient risk factorsAdministrative claims dataCOVID-19 infectionAdverse event informationOngoing global pandemicClinical characteristicsFracture patientsPostoperative eventsPreoperative variablesPropensity matching
2020
Postoperative Pressure Ulcers After Geriatric Hip Fracture Surgery Are Predicted by Defined Preoperative Comorbidities and Postoperative Complications.
Galivanche AR, Kebaish KJ, Adrados M, Ottesen TD, Varthi AG, Rubin LE, Grauer JN. Postoperative Pressure Ulcers After Geriatric Hip Fracture Surgery Are Predicted by Defined Preoperative Comorbidities and Postoperative Complications. Journal Of The American Academy Of Orthopaedic Surgeons 2020, 28: 342-351. PMID: 31567615, DOI: 10.5435/jaaos-d-19-00104.Peer-Reviewed Original ResearchConceptsPostoperative pressure ulcersHip fracture surgeryPostoperative complicationsPressure ulcersRisk factorsPreoperative comorbiditiesFracture surgerySurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseGeriatric hip fracture patientsGeriatric hip fracture surgeryQuality Improvement Program databaseMultivariate regressionNSQIP Participant Use FilePreoperative risk factorsHip fracture patientsImprovement Program databaseUrinary tract infectionElevated platelet countInsulin-dependent diabetesParticipant Use FilePressure ulcer developmentQuality Improvement ProgramPostoperative deliriumPostoperative pneumonia
2019
Dialysis Dependence Is Associated With Significantly Increased Odds of Perioperative Adverse Events After Geriatric Hip Fracture Surgery Even After Controlling for Demographic Factors and Comorbidities
Ottesen TD, Yurter A, Shultz BN, Galivanche AR, Zogg CK, Bovonratwet P, Rubin LE, Grauer JN. Dialysis Dependence Is Associated With Significantly Increased Odds of Perioperative Adverse Events After Geriatric Hip Fracture Surgery Even After Controlling for Demographic Factors and Comorbidities. JAAOS Global Research And Reviews 2019, 3: e086. PMID: 31592508, PMCID: PMC6754213, DOI: 10.5435/jaaosglobal-d-19-00086.Peer-Reviewed Original ResearchHip fracture surgeryDialysis-dependent patientsPerioperative adverse eventsAdverse eventsFracture surgeryDialysis dependenceDialysis patientsHip fractureGreater oddsNational Surgical Quality Improvement Program databaseGeriatric hip fracture surgeryRisk-adjusted logistic regressionQuality Improvement Program databaseInstitutional cohort studyNational patient populationPreoperative dialysis dependenceMinor adverse eventsHip fracture careImprovement Program databaseMajor adverse eventsDemographic factorsUnplanned readmissionCohort studyPerioperative periodPostoperative day
2018
Timing of Adverse Events Following Geriatric Hip Fracture Surgery: A Study of 19,873 Patients in the American College of Surgeons National Surgical Quality Improvement Program.
Bohl DD, Samuel AM, Webb ML, Lukasiewicz AM, Ondeck NT, Basques BA, Anandasivam NS, Grauer JN. Timing of Adverse Events Following Geriatric Hip Fracture Surgery: A Study of 19,873 Patients in the American College of Surgeons National Surgical Quality Improvement Program. The American Journal Of Orthopedics 2018, 47 PMID: 30296324, DOI: 10.12788/ajo.2018.0080.Peer-Reviewed Original ResearchConceptsSurgeons National Surgical Quality Improvement ProgramNational Surgical Quality Improvement ProgramGeriatric hip fracture surgerySurgical Quality Improvement ProgramHip fracture surgeryAdverse eventsPostoperative day 30Quality Improvement ProgramFracture surgeryAmerican CollegeDay 30Urinary tract infections 7Median postoperative dayProspective surgical registryPostoperative adverse eventsSpecific adverse eventsInfection 7Mortality 11Pneumonia 4Postoperative dayHip fractureCardiac arrestClinical surveillancePatient counselingMyocardial infarctionDiscriminative Ability for Adverse Outcomes After Surgical Management of Hip Fractures
Ondeck NT, Bovonratwet P, Ibe IK, Bohl DD, McLynn RP, Cui JJ, Baumgaertner MR, Grauer JN. Discriminative Ability for Adverse Outcomes After Surgical Management of Hip Fractures. Journal Of Orthopaedic Trauma 2018, 32: 231-237. PMID: 29401098, DOI: 10.1097/bot.0000000000001140.Peer-Reviewed Original ResearchConceptsElixhauser comorbidity measuresCharlson Comorbidity IndexExtended hospital stayAdverse outcomesHip fractureComorbidity indexAdverse eventsSurgical managementLargest discriminative abilityHospital stayDiscriminative abilityDemographic factorsHospital adverse outcomesPrognostic Level IIIHip fracture surgeryMinor adverse eventsSevere adverse eventsHip fracture studiesNational Inpatient SampleOverall discriminative abilityAppropriate patient expectationsPostoperative complicationsFrailty indexFracture surgeryMedical managementThe Rothman Index Is Associated With Postdischarge Adverse Events After Hip Fracture Surgery in Geriatric Patients
McLynn RP, Ottesen TD, Ondeck NT, Cui JJ, Rubin LE, Grauer JN. The Rothman Index Is Associated With Postdischarge Adverse Events After Hip Fracture Surgery in Geriatric Patients. Clinical Orthopaedics And Related Research® 2018, 476: 997-1006. PMID: 29419631, PMCID: PMC5916609, DOI: 10.1007/s11999.0000000000000186.Peer-Reviewed Original ResearchConceptsRothman Index scoresPostdischarge adverse eventsHip fracture surgeryPostdischarge adverse outcomesAdverse eventsASA classRothman IndexHip fractureFracture surgeryIndex scoreGeriatric patientsAdverse outcomesMedical CenterOverall patient statusHip fracture careRoutine laboratory valuesMeasures of comorbidityRisk of complicationsBody mass indexAge 65 yearsPlan of careVulnerable patient populationCondition of patientsAcademic medical centerElectronic medical recordsHow Common—and How Serious— Is Clostridium difficile Colitis After Geriatric Hip Fracture? Findings from the NSQIP Dataset
Bovonratwet P, Bohl DD, Russo GS, Ondeck NT, Nam D, Della Valle CJ, Grauer JN. How Common—and How Serious— Is Clostridium difficile Colitis After Geriatric Hip Fracture? Findings from the NSQIP Dataset. Clinical Orthopaedics And Related Research® 2018, 476: 453-462. PMID: 29443839, PMCID: PMC6260047, DOI: 10.1007/s11999.0000000000000099.Peer-Reviewed Original ResearchConceptsHip fracture surgeryClostridium difficile colitisDifficile colitisGeriatric hip fracturesChronic care facilitiesHip fractureFracture surgeryPostoperative lengthGeriatric patientsHigh riskPreoperative anemiaCurrent smokersCare facilitiesStrict hand hygieneProphylactic antibiotic regimensFuture prospective studiesHospital quality metricsLarge database studiesStepwise multivariate modelLarge national databasePostdischarge dataAntibiotic regimensInfectious diagnosisPreoperative factorsProphylactic antibiotics
2017
Does Preoperative Pneumonia Affect Complications of Geriatric Hip Fracture Surgery?
Patterson JT, Bohl DD, Basques BA, Arzeno AH, Grauer JN. Does Preoperative Pneumonia Affect Complications of Geriatric Hip Fracture Surgery? The American Journal Of Orthopedics 2017, 46: e177-e185. PMID: 28666049.Peer-Reviewed Original ResearchConceptsHip fracture repairHip fracture patientsGeriatric hip fracture patientsHip fracture surgeryPreoperative pneumoniaFracture patientsAdverse eventsFracture repairFracture surgeryAdverse outcomesNational Surgical Quality Improvement Program databaseEarly hip fracture surgeryGeriatric hip fracture surgeryQuality Improvement Program databaseChronic obstructive pulmonary diseaseUnderweight body mass indexSerious adverse eventsImprovement Program databaseObstructive pulmonary diseaseTime of surgeryBody mass indexPreoperative anemiaDelaying surgeryRetrospective cohortHip fracture
2014
Diabetes Confers Little to No Increased Risk of Postoperative Complications After Hip Fracture Surgery in Geriatric Patients
Golinvaux NS, Bohl DD, Basques BA, Baumgaertner MR, Grauer JN. Diabetes Confers Little to No Increased Risk of Postoperative Complications After Hip Fracture Surgery in Geriatric Patients. Clinical Orthopaedics And Related Research® 2014, 473: 1043-1051. PMID: 25238805, PMCID: PMC4317441, DOI: 10.1007/s11999-014-3945-7.Peer-Reviewed Original ResearchConceptsMinor adverse eventsSerious adverse eventsHip fracture surgeryInsulin-dependent diabetesIndividual serious adverse eventsAdverse eventsFracture surgeryHip fractureGeriatric patientsRelative riskSurgeons National Surgical Quality Improvement ProgramNational Surgical Quality Improvement ProgramGreater riskSurgical Quality Improvement ProgramQuestions/PurposesWePostoperative adverse eventsHistory of diabetesPostoperative myocardial infarctionInfluence of diabetesLength of hospitalizationGroup of patientsNoninsulin-dependent diabetesLength of stayCase-control studyCounseling of patients