2023
Bone Mass Changes Following Percutaneous Radiofrequency Ablation, Osteoplasty, Reinforcement, and Internal Fixation of Periacetabular Osteolytic Metastases
Jiang W, Caruana D, Dussik C, Conway D, Latich I, Chapiro J, Lindskog D, Friedlaender G, Lee F. Bone Mass Changes Following Percutaneous Radiofrequency Ablation, Osteoplasty, Reinforcement, and Internal Fixation of Periacetabular Osteolytic Metastases. Journal Of Clinical Medicine 2023, 12: 4613. PMID: 37510728, PMCID: PMC10380351, DOI: 10.3390/jcm12144613.Peer-Reviewed Original ResearchPercutaneous radiofrequency ablationBone mass changesCT scanMedian survivalHounsfield unitsOsteolytic metastasesRadiofrequency ablationBone massCancer-induced bone lossSuperior median survivalAvailable CT scansThree-dimensional volumetric analysisInternal screw fixationPeriacetabular areaPercutaneous stabilizationBone lossInternal fixationSingle institutionOrthopedic interventionsScrew fixationPatientsMonthsVolumetric analysisSurvivalScans
2020
Bone Scans Have Little Utility in the Evaluation of Well-Differentiated Cartilaginous Lesions of the Humerus.
Samuel AM, Munger AM, Lee FY, Friedlaender GE, Ibe IK, Lindskog DM. Bone Scans Have Little Utility in the Evaluation of Well-Differentiated Cartilaginous Lesions of the Humerus. Orthopedics 2020, 43: e498-e502. PMID: 32882054, DOI: 10.3928/01477447-20200827-05.Peer-Reviewed Original ResearchConceptsRadionuclide bone scanBone scanMRI scansPositive findingsNegative findingsMagnetic resonance imaging (MRI) scansBone scan findingsProgression of lesionsResonance imaging scansDiagnosis of enchondromaAcademic medical centerBivariate logistic regressionAssociation of boneScan findingsAggressive featuresRadiographic findingsEndosteal scallopingBenign enchondromaImaging scansMedical recordsMedical CenterMalignant lesionsCartilaginous lesionsEnchondromaPatients
2018
Immuno-oncologic Approach to Musculoskeletal Tumors
Ibe I, Sahlstrom A, Nguyen M, Lindskog D, Friedlaender G, Lee F. Immuno-oncologic Approach to Musculoskeletal Tumors. Techniques In Orthopaedics 2018, 33: 140-147. DOI: 10.1097/bto.0000000000000305.Peer-Reviewed Original ResearchImmune systemImmuno-oncologic therapiesSoft tissue sarcomasHost immune surveillanceActive immune responseTreatment of boneImmune therapyTumor burdenTissue sarcomasTreatment of cancerTreatment optionsMusculoskeletal tumorsComprehensive careImproved outcomesImmune surveillanceImmune responseOrthopedic oncologyMalignant cellsImmunotherapyCancer cellsPrecision medicineDistant sitesPatientsUnderlying mechanismTherapy
2016
Case of a Missed Giant Cell Tumor of Bone: An Opportunity to Observe its Natural History Disease.
Russo GS, Rubio DR, Yacob A, Lindskog DM, Alomari AK, Friedlaender GE. Case of a Missed Giant Cell Tumor of Bone: An Opportunity to Observe its Natural History Disease. Connecticut Medicine 2016, 80: 399-403. PMID: 29782126.Peer-Reviewed Case Reports and Technical NotesConceptsGiant cell tumorAnterior cruciate ligamentCell tumorsIncidental findingRoutine preoperative imagingPre-operative MRIInitial MRIPreoperative imagingSecond MRIMetaphyseal lesionsCruciate ligamentEnlarged massBenign neoplasmsRetrospective evaluationNatural historyTumorsYoung womenHistory diseaseMRIBoneLesionsPainPatientsNeoplasmsHistology
2005
The effect of counterface roughness on the wear of UHMWPE for rectangular wear paths
Turell M, Friedlaender G, Wang A, Thornhill T, Bellare A. The effect of counterface roughness on the wear of UHMWPE for rectangular wear paths. Wear 2005, 259: 984-991. DOI: 10.1016/j.wear.2005.01.050.Peer-Reviewed Original ResearchReplacement prosthesisGait cycleFemoral headTotal hip replacement prosthesesWeight lossCalf serumJoint replacement prosthesesAcetabular cupHip replacement prosthesesProsthesisCurrent studyPhysiological loading conditionsUHMWPE cupDiluted calf serumTotal joint replacement prosthesesVolumetric wear ratePrevious studiesFactorsPatients
1999
LONG-TERM FOLLOW-UP OF PATIENTS WITH OSTEOCHONDRAL ALLOGRAFTS A Correlation Between Immunologic Responses and Clinical Outcome
Friedlaender G, Strong D, Tomford W, Mankin H. LONG-TERM FOLLOW-UP OF PATIENTS WITH OSTEOCHONDRAL ALLOGRAFTS A Correlation Between Immunologic Responses and Clinical Outcome. Orthopedic Clinics Of North America 1999, 30: 583-588. PMID: 10471763, DOI: 10.1016/s0030-5898(05)70111-5.Peer-Reviewed Original ResearchConceptsClinical outcomesImmunologic responseHistocompatibility antigensLong-term clinical outcomesLong-term resultsFrozen bone allograftsPresence of sensitizationFrozen osteochondral allograftsImmune responseBone allograftAnimal modelsSatisfactory outcomeOsteochondral allograftsReconstructive alternativeClass IIBiologic successAllograftsOutcomesAntigenResponsePatientsHumansSensitization
1990
Orthopaedic manifestations of sickle-cell disease.
Huo M, Friedlaender G, Marsh J. Orthopaedic manifestations of sickle-cell disease. The Yale Journal Of Biology And Medicine 1990, 63: 195-207. PMID: 2238715, PMCID: PMC2589295.Peer-Reviewed Original ResearchConceptsSickle cell diseaseOrthopaedic manifestationsMajor orthopaedic manifestationsSurgical treatment alternativesFirst case reportJoint sequelaeSerious complicationsClinical entityCase reportDisorder pathophysiologyAccurate diagnosisTreatment alternativesDiseasePathophysiologyOsteonecrosisManifestationsNumerous investigatorsSepsisArthritisMorbidityOsteomyelitisPainComplicationsSequelaePatients
1988
Angiosarcoma associated with foreign body material: A report of three cases
Jennings T, Peterson L, Axiotis C, Friedlaender G, Cooke R, Rosai J. Angiosarcoma associated with foreign body material: A report of three cases. Cancer 1988, 62: 2436-2444. PMID: 3052791, DOI: 10.1002/1097-0142(19881201)62:11<2436::aid-cncr2820621132>3.0.co;2-j.Peer-Reviewed Original Research
1986
Indium-111 platelet scintigraphy for the diagnosis of acute venous thrombosis.
Ezekowitz M, Pope C, Sostman H, Smith E, Glickman M, Rapoport S, Sniderman K, Friedlaender G, Pelker R, Taylor F. Indium-111 platelet scintigraphy for the diagnosis of acute venous thrombosis. Circulation 1986, 73: 668-674. PMID: 3948370, DOI: 10.1161/01.cir.73.4.668.Peer-Reviewed Original ResearchConceptsPlatelet scintigraphyContrast venographyGroup IIVenous thrombosisLower limb venous thrombosisGroup IIndium-111 platelet scintigraphyAcute venous thrombosisHigh-risk patientsMajor orthopedic proceduresPositive venogramsIntravenous heparinSymptomatic patientsConsecutive patientsActive thrombosisOrthopedic proceduresSingle injectionScintigraphyVenographyPatientsBlinded observersIndium-111Positive findingsFurther evaluationThrombosis
1985
Loose Body Within the Glenohumeral Joint in Recurrent Anterior Dislocation
Gould R, Rosenfield A, Friedlaender G. Loose Body Within the Glenohumeral Joint in Recurrent Anterior Dislocation. Journal Of Computer Assisted Tomography 1985, 9: 404-406. PMID: 3973177, DOI: 10.1097/00004728-198503000-00040.Peer-Reviewed Original Research
1984
Studies on the antigenicity of bone. II. Donor-specific anti-HLA antibodies in human recipients of freeze-dried allografts.
Friedlaender G, Strong D, Sell K. Studies on the antigenicity of bone. II. Donor-specific anti-HLA antibodies in human recipients of freeze-dried allografts. Journal Of Bone And Joint Surgery 1984, 66: 107-12. PMID: 6361041, DOI: 10.2106/00004623-198466010-00014.Peer-Reviewed Original ResearchConceptsDonor-specific anti-HLA antibodiesAnti-HLA antibodiesBone allograftImmune responseFreeze-dried bone allograftFreeze-dried allograftNinth patientAllograft donorsClinical eventsAllograftsPatientsHuman recipientsGraftAdverse effectsRecipientsAntibodiesMonthsBenign processSuch responsesResponseHLADonorsTissue types
1983
Biomechanical Properties of Bone Allografts
Pelker R, Friedlaender G, Markham T. Biomechanical Properties of Bone Allografts. Clinical Orthopaedics And Related Research® 1983, 174: 54-57. PMID: 6339144, DOI: 10.1097/00003086-198304000-00009.Peer-Reviewed Original ResearchConceptsOrthopaedic oncology serviceLow-grade tumorsPresence of recurrenceRelationship of complicationsMassachusetts General HospitalAllograft fractureOncology servicesAllograft implantationFunctional statusSkin sloughGeneral HospitalBone allograftIntramedullary rodFunctional restorationPatientsBenign conditionsResectionBone conditionsCadaveric segmentsComplicationsGraftBiomechanical propertiesTumorsMore yearsInfection
1981
Avascular necrosis of bone in Hodgkin's disease patients treated with combined modality therapy
Prosnitz L, Lawson J, Friedlaender G, Farber L, Pezzimenti J. Avascular necrosis of bone in Hodgkin's disease patients treated with combined modality therapy. Cancer 1981, 47: 2793-2797. PMID: 7260869, DOI: 10.1002/1097-0142(19810615)47:12<2793::aid-cncr2820471206>3.0.co;2-a.Peer-Reviewed Original ResearchConceptsAvascular necrosisHodgkin's diseaseModality therapyDisease patientsHumeral head involvementAdvanced Hodgkin's diseaseHodgkin's disease patientsLong-term survivorsBilateral hip replacementPossible serious consequencesNinth patientComplete remissionCorticosteroid administrationCumulative incidenceCombination chemotherapyHead involvementModality programConsiderable disabilityLarge dosesPatientsHip replacementFemoral headChemotherapeutic agentsNecrosisChemotherapy
1978
Clinical Evaluation of Freezedried Bone Allografts in Periodontal Osseous Defects‐Part II
Sepe W, Bowers G, Lawrence J, Friedlaender G, Koch R. Clinical Evaluation of Freezedried Bone Allografts in Periodontal Osseous Defects‐Part II. The Journal Of Periodontology 1978, 49: 9-14. PMID: 340637, DOI: 10.1902/jop.1978.49.1.9.Peer-Reviewed Original Research
1976
The use of freeze-dried bone in middle-third face advancements
Epker B, Friedlaender G, Wolford L, West R. The use of freeze-dried bone in middle-third face advancements. Oral Surgery Oral Medicine Oral Pathology And Oral Radiology 1976, 42: 278-289. PMID: 787861, DOI: 10.1016/0030-4220(76)90161-4.Peer-Reviewed Original ResearchConceptsFreeze-dried bone allograftPrimary operative procedureFreeze-dried boneMedical Research InstituteNaval Medical Research InstituteSmall sequestrumAdditional surgeryOperative procedureClinical infectionBone allograftPatientsMaxillary areaAutogenous boneGraft materialInfectionTissue banksIntraoral exposureAllograftsBoneGraftMorbiditySequestrumComplicationsSurgeryOsteotomy