2024
Efficacy of Voluntary Medical Male Circumcision to Prevent HIV Infection Among Men Who Have Sex With Men : A Randomized Controlled Trial.
Gao Y, Zhan Y, Sun Y, Zheng W, Zhang W, Fu L, Guo Z, Lin Y, Li Y, Zheng L, Zhan Y, Zhu Z, Duan J, Zhang G, Huang T, Su B, Yu M, Wu G, Ouyang L, Zhao J, Wang G, Zhou Y, Qian H, Fitzpatrick T, Vermund S, Zou H. Efficacy of Voluntary Medical Male Circumcision to Prevent HIV Infection Among Men Who Have Sex With Men : A Randomized Controlled Trial. Annals Of Internal Medicine 2024, 177: 719-728. PMID: 38801778, DOI: 10.7326/m23-3317.Peer-Reviewed Original ResearchVoluntary medical male circumcisionEfficacy of VMMCPreventing incident HIV infectionsRandomized controlled trialsMedical male circumcisionIncident HIV infectionIntervention groupInsertive anal intercoursePractice insertive anal intercourseMale circumcisionAnal intercourseIncidence rate of syphilisHIV infectionRates of syphilisMale sex partnersSexually transmitted infectionsIntention-to-treat analysisPrevent HIV infectionHIV incidenceControl groupHIV riskIncidence rateHerpes simplex virus type 2HIV seroconversionSelf-report
2023
Increasing Spiritual Beliefs are Associated With Lower HIV Incidence Among Black Men Who Have Sex With Men: Results From HPTN 061 Longitudinal Study
Ransome Y, Taggart T, Huang A, Vermund S, Mayer K, Nunn A. Increasing Spiritual Beliefs are Associated With Lower HIV Incidence Among Black Men Who Have Sex With Men: Results From HPTN 061 Longitudinal Study. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2023, 94: 196-202. PMID: 37850978, DOI: 10.1097/qai.0000000000003278.Peer-Reviewed Original ResearchConceptsHIV seroconversionHIV incidenceBehavioral HIV prevention interventionsLower HIV incidenceProportional hazards regressionHIV prevention interventionsBlack menSpiritual beliefsOne-unit increaseHazards regressionLongitudinal riskPrevention interventionsHIVBiomedical assessmentLower hazard rateLongitudinal studyMenMonthsSeroconversionLongitudinal analysisReligious service attendanceIncidenceBaselineBMSMHigher proportion
2020
HIV Seroconversion and Types of Relationships Among Men Who Have Sex With Men: A Cohort Study in China.
Sun X, Wang C, Zhao K, Zhang L, Li M, Sun D, Shu W, Ruan Y, Zhang J, Vermund SH, Li D, Hu Y. HIV Seroconversion and Types of Relationships Among Men Who Have Sex With Men: A Cohort Study in China. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2020, 83: 365-372. PMID: 31913999, PMCID: PMC7055498, DOI: 10.1097/qai.0000000000002264.Peer-Reviewed Original ResearchConceptsHIV seroconversionSeroconversion riskHIV seroconversion ratesHIV seroconversion riskMultivariable Cox regressionHIV-negative menIncident HIV infectionRegular sexual partnersRelative excess riskUnprotected anal sexSexual behaviorLast sexual encounterUnsafe sexual behaviorSafer sex educationSeroconversion ratesCohort studyHIV infectionRisky sexual behaviorHIV statusCox regressionExcess riskRisk factorsRegular partnersLow educational attainmentCasual partners
2013
High HIV Incidence among Persons Who Inject Drugs in Pakistan: Greater Risk with Needle Sharing and Injecting Frequently among the Homeless
Samo RN, Altaf A, Agha A, Pasha O, Rozi S, Memon A, Azam S, Blevins M, Vermund SH, Shah SA. High HIV Incidence among Persons Who Inject Drugs in Pakistan: Greater Risk with Needle Sharing and Injecting Frequently among the Homeless. PLOS ONE 2013, 8: e81715. PMID: 24358123, PMCID: PMC3864804, DOI: 10.1371/journal.pone.0081715.Peer-Reviewed Original ResearchConceptsIncidence of HIVHIV seroconversionIncidence rateMultivariable Cox regression analysisNeedle/syringe exchangeCohort of PWIDHIV-seronegative personsHigh HIV incidenceOpiate substitution therapyCox regression analysisHIV incidence ratesHIV risk reductionSharing of syringesRisk reductionSubstance abuse treatmentSeronegative personsCohort studyRisk reduction programsHIV incidencePerson yearsSubstitution therapyDaily injectionsNeedle sharingRisk factorsPrevalence rates
2011
Experience in international clinical research: the HIV Prevention Trials Network
Sista ND, Karim Q, Hinson K, Donnell D, Eshleman SH, Vermund SH. Experience in international clinical research: the HIV Prevention Trials Network. Clinical Investigation 2011, 1: 1609-1618. PMID: 22348195, PMCID: PMC3281583, DOI: 10.4155/cli.11.156.Peer-Reviewed Original ResearchHIV Prevention Trials NetworkCombination antiretroviral therapyHIV transmissionClinical trialsPrevention strategiesTrials NetworkHPTN 052 studyOpiate agonist therapySerodiscordant sexual partnersHIV testing ratesPre-exposure prophylaxisHIV prevention strategiesPivotal efficacy trialsInjection drug usersHigh-risk behaviorsPublic health policyAgonist therapyAntiretroviral therapyHIV seroconversionInfected partnerMiddle-income countriesTrial feasibilityAntiretroviral drugsHPTN 068Efficacy trials
2009
Preventing HIV in Developing Countries: Status of Biomedical Interventions
Vermund S. Preventing HIV in Developing Countries: Status of Biomedical Interventions. The FASEB Journal 2009, 23: 199.1-199.1. DOI: 10.1096/fasebj.23.1_supplement.199.1.Peer-Reviewed Original ResearchHIV Prevention Trials NetworkPrevention of motherHIV drug resistanceNeedle exchange programsDNA boostBehavior changeHIV seroconversionHIV seroincidenceEarly therapyPregnant womenHSV-2Clinical trialsHIVMale circumcisionDrug addiction treatmentDrug resistanceTrials NetworkAddiction treatmentBiomedical interventionsSeroincidenceInfantsRisk reductionTherapyPrevention challengesEfficacy