2024
Assessing Direct and Spillover Effects of Intervention Packages in Network-randomized Studies
Buchanan A, Hernández-Ramírez R, Lok J, Vermund S, Friedman S, Forastiere L, Spiegelman D. Assessing Direct and Spillover Effects of Intervention Packages in Network-randomized Studies. Epidemiology 2024, 35: 481-488. PMID: 38709023, DOI: 10.1097/ede.0000000000001742.Peer-Reviewed Original ResearchIntervention packageEffectiveness of interventional packageImprove intervention deliveryPeer education interventionHIV prevention trialsPeer educator trainingMarginal structural modelsPublic health impactHIV risk behaviorsIntervention deliveryIntervention NetworkEducational interventionParticipant visitsPrevention trialsFollow-up visitRisk behaviorsHealth impactsInterventionEducational trainingParticipantsSpillover effectsVisitsHIVExposed networksPeer
2019
Treatment as Prevention: Concepts and Challenges for Reducing HIV Incidence
Brault MA, Spiegelman D, Hargreaves J, Nash D, Vermund SH. Treatment as Prevention: Concepts and Challenges for Reducing HIV Incidence. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2019, 82: s104-s112. PMID: 31658196, PMCID: PMC6820703, DOI: 10.1097/qai.0000000000002168.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyHIV transmissionHIV plasma loadReducing HIV IncidenceHIV prevention trialsCommunity-level interventionsDeployable vaccineViral suppressionHIV testingHIV incidencePrevention trialsUninfected personsChronic conditionsHIV investmentsEarly treatmentTreat strategySexual partnersViral expressionTransmission riskHIVTrialsTreatmentInconsistent findingsPreventionSaharan Africa