2024
Assessing Direct and Spillover Effects of Intervention Packages in Network-randomized Studies
Buchanan A, Hernández-Ramírez R, Lok J, Vermund S, Friedman S, Forastiere L, Spiegelman D. Assessing Direct and Spillover Effects of Intervention Packages in Network-randomized Studies. Epidemiology 2024, 35: 481-488. PMID: 38709023, DOI: 10.1097/ede.0000000000001742.Peer-Reviewed Original ResearchIntervention packageEffectiveness of interventional packageImprove intervention deliveryPeer education interventionHIV prevention trialsPeer educator trainingMarginal structural modelsPublic health impactHIV risk behaviorsIntervention deliveryIntervention NetworkEducational interventionParticipant visitsPrevention trialsFollow-up visitRisk behaviorsHealth impactsInterventionEducational trainingParticipantsSpillover effectsVisitsHIVExposed networksPeer
2023
Risk of death and readmission among individuals with heart failure and HIV: A systematic review and meta-analysis
Zhou Y, Zhang X, Gao Y, Alvi R, Erqou S, Chen Y, Wang H, Wang W, Li X, Zanni M, Neilan T, Vermund S, Qian H, Qian F. Risk of death and readmission among individuals with heart failure and HIV: A systematic review and meta-analysis. Journal Of Infection And Public Health 2023, 17: 70-75. PMID: 37992436, DOI: 10.1016/j.jiph.2023.11.004.Peer-Reviewed Original ResearchConceptsHeart failureHF patientsRisk of HFHuman immunodeficiency virus statusPoor HF outcomesRisk of deathWeb of ScienceCause deathCause readmissionHF outcomesAdult patientsCohort studyHIV infectionHIV statusCochrane LibraryIndependent associationVirus statusHigh riskDeath outcomesHIVReadmissionPatientsSystematic reviewSystematic searchRiskIncreasing Spiritual Beliefs are Associated With Lower HIV Incidence Among Black Men Who Have Sex With Men: Results From HPTN 061 Longitudinal Study
Ransome Y, Taggart T, Huang A, Vermund S, Mayer K, Nunn A. Increasing Spiritual Beliefs are Associated With Lower HIV Incidence Among Black Men Who Have Sex With Men: Results From HPTN 061 Longitudinal Study. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2023, 94: 196-202. PMID: 37850978, DOI: 10.1097/qai.0000000000003278.Peer-Reviewed Original ResearchConceptsHIV seroconversionHIV incidenceBehavioral HIV prevention interventionsLower HIV incidenceProportional hazards regressionHIV prevention interventionsBlack menSpiritual beliefsOne-unit increaseHazards regressionLongitudinal riskPrevention interventionsHIVBiomedical assessmentLower hazard rateLongitudinal studyMenMonthsSeroconversionLongitudinal analysisReligious service attendanceIncidenceBaselineBMSMHigher proportionHigh-Level Drug-Resistant Mutations among HIV-1 Subtype A6 and CRF02_AG in Kazakhstan
Sanaubarova A, Pujol-Hodge E, Dzissyuk N, Lemey P, Vermund S, Brown A, Ali S. High-Level Drug-Resistant Mutations among HIV-1 Subtype A6 and CRF02_AG in Kazakhstan. Viruses 2023, 15: 1407. PMID: 37515095, PMCID: PMC10384832, DOI: 10.3390/v15071407.Peer-Reviewed Original ResearchConceptsAntiretroviral therapySubtype A6Drug-resistant mutationsDrug resistanceEffective antiretroviral therapySuppressive antiretroviral therapyAntiretroviral drug resistanceDrug resistance monitoringHigh-level drug resistanceDrug regimensHIV incidenceHIV epidemicHIV-1Sustained transmissionMolecular epidemiologySubtypesPLHIVHIVG190SDifferent mutational pathwaysMutationsK101ED67NHigh levelsA62V
2022
Antiretroviral therapy resistance mutations among HIV infected people in Kazakhstan
Mukhatayeva A, Mustafa A, Dzissyuk N, Issanov A, Mukhatayev Z, Bayserkin B, Vermund SH, Ali S. Antiretroviral therapy resistance mutations among HIV infected people in Kazakhstan. Scientific Reports 2022, 12: 17195. PMID: 36229577, PMCID: PMC9562405, DOI: 10.1038/s41598-022-22163-7.Peer-Reviewed Original Research“If it weren’t for my traditional healer, I would be dead”: Engaging traditional healers to support people living with HIV in rural Mozambique
Audet CM, Pettapiece-Phillips M, Tian Y, Shepherd BE, Vermund SH, Salato J. “If it weren’t for my traditional healer, I would be dead”: Engaging traditional healers to support people living with HIV in rural Mozambique. PLOS ONE 2022, 17: e0270565. PMID: 35763519, PMCID: PMC9239464, DOI: 10.1371/journal.pone.0270565.Peer-Reviewed Original ResearchConceptsTraditional healersPsychosocial supportCommunity health worker interventionPre-post intervention study designWorker interventionHealth worker interventionMedication possession ratioMedication side effectsIntervention study designPositive test resultsHome-based supportObserved therapyPossession ratioClinical outcomesHIV treatmentPoor adherencePost-intervention participantsHealth facilitiesPatient's desireSide effectsZambézia ProvinceCare servicesStudy designHIVTherapyFactors that Affect the Frequency of HIV Testing in College Men Who Have Sex with Men — Northeast China, 2017–2018
Li M, Wu H, Shu W, Li Z, Yan H, Hui H, Li H, Yang Z, Vermund SH, Hu Y. Factors that Affect the Frequency of HIV Testing in College Men Who Have Sex with Men — Northeast China, 2017–2018. China CDC Weekly 2022, 4: 549-553. PMID: 35813888, PMCID: PMC9260086, DOI: 10.46234/ccdcw2022.118.Peer-Reviewed Original ResearchHuman immunodeficiency virus (HIV) testingHIV testing frequencyHIV testing servicesPrevalence of HIVRecreational drug usePublic health practiceHIV testingHIV transmissionYoung MSMVirus testingDrug useHealth practicesStudy periodMSMOnline interventionWhole study periodMenTesting servicesMore social contactsSexTesting frequencySocial contactHIVPrevalenceIntersecting Pandemics of HIV and SARS-CoV-2: Commentary on the Special Issue
Vermund SH. Intersecting Pandemics of HIV and SARS-CoV-2: Commentary on the Special Issue. Current HIV/AIDS Reports 2022, 19: 1-4. PMID: 35192108, PMCID: PMC8862004, DOI: 10.1007/s11904-022-00599-w.Peer-Reviewed Original Research
2021
Assisted Partner Notification and Uptake of HIV Testing among Men Who Have Sex with Men: A Randomized Controlled Trial in China
Hu QH, Qian HZ, Li JM, Leuba SI, Chu ZX, Turner D, Ding HB, Jiang YJ, Vermund SH, Xu JJ, Shang H. Assisted Partner Notification and Uptake of HIV Testing among Men Who Have Sex with Men: A Randomized Controlled Trial in China. The Lancet Regional Health - Western Pacific 2021, 12: 100171. PMID: 34527967, PMCID: PMC8356101, DOI: 10.1016/j.lanwpc.2021.100171.Peer-Reviewed Original ResearchHIV testing servicesAssisted partner notificationPartner notificationUptake of HIVPN groupIndex caseHIV testingSexual partnersHIV statusHIV self-test kitsMonths of randomizationCommunity health workersCommunity-based organizationsSelf-test kitsFemale sexual partnersControlled TrialsPrimary outcomePN interventionHealth workersStudy groupHIVMSMSparse evidenceHeterosexual partnersPN strategiesInteraction of Religion/Spirituality With Internalized HIV Stigma, Depression, Alcohol Use, and Sexual Risk Among Black Men Who Have Sex With Men: The 6 City HPTN 061 Study
Taggart T, Mayer KH, Vermund SH, Huang S, Hayashi K, Ransome Y. Interaction of Religion/Spirituality With Internalized HIV Stigma, Depression, Alcohol Use, and Sexual Risk Among Black Men Who Have Sex With Men: The 6 City HPTN 061 Study. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2021, 87: e188-e197. PMID: 33633033, PMCID: PMC8131231, DOI: 10.1097/qai.0000000000002667.Peer-Reviewed Original ResearchConceptsInternalized HIV stigmaHIV stigmaDepressive symptomsInfluence of drugsAlcohol useActivity scoreHIV Prevention Trials Network 061 studyDepressive symptom scoresHPTN 061 StudyBlack menSymptom scoresFuture intervention researchAnal intercourseHigh riskSymptomsRisk behaviorsSexual riskSubstance useBMSMBaseline dataDrugsHIVMenGeneralized structural equation modelScoresThe Historic Elimination of Mother-to-Child HIV and Syphilis Transmission in Puerto Rico.
Vermund SH, Febo I. The Historic Elimination of Mother-to-Child HIV and Syphilis Transmission in Puerto Rico. Puerto Rico Health Sciences Journal 2021, 40: 3-5. PMID: 33876911, PMCID: PMC8363137.Peer-Reviewed Original ResearchConceptsHigh background prevalenceElimination of HIVWorld Health OrganizationChildren HIVInfection overallPerinatal transmissionAntenatal servicesBackground prevalenceHIV riskSyphilis transmissionSyphilis therapyHIVHealth OrganizationSyphilisMothersPuerto RicoInfantsTherapyPrevalenceCareEliminationWomenAssociation of HIV infection and cognitive impairment in older adults: A meta-analysis
Deng L, Zhang X, Gao Y, Turner D, Qian F, Lu H, Vermund SH, Zhang Y, Qian HZ. Association of HIV infection and cognitive impairment in older adults: A meta-analysis. Ageing Research Reviews 2021, 68: 101310. PMID: 33640473, PMCID: PMC10767715, DOI: 10.1016/j.arr.2021.101310.Peer-Reviewed Original ResearchConceptsHIV infectionCognitive impairmentOlder adultsOdds ratioHuman immunodeficiency virus (HIV) infectionMean differenceMotor/psychomotorImmunodeficiency virus infectionMajor cognitive domainsNewcastle-Ottawa ScaleConfidence intervalsRisk of biasPooled odds ratioCross-sectional studyRandom-effects modelIncome countriesCognitive domainsGlobal cognitive impairmentExecutive functionOlder PLWHVirus infectionHigh-income countriesHIVPLWHUpper middle-income countries
2020
Trends of HIV, hepatitis C virus and syphilis seroprevalence among injection and non-injection drug users in southwestern China, 2010–2017
Jiang H, Zhang X, Zhang C, Lu R, Zhou C, Ouyang L, Xing H, Vermund SH, Shao Y, Ruan Y, Wu G, Qian HZ. Trends of HIV, hepatitis C virus and syphilis seroprevalence among injection and non-injection drug users in southwestern China, 2010–2017. AIDS Care 2020, 36: 612-617. PMID: 33345591, PMCID: PMC10767711, DOI: 10.1080/09540121.2020.1856320.Peer-Reviewed Original ResearchNon-injection drug usersHepatitis C virusDrug use behaviorsDrug usersHCV prevalenceC virusRisky drug use behaviorsTrends of HIVCross-sectional surveySyphilis seroprevalenceHIV prevalenceHIV transmissionPrevalence trendsPWIDDrug useHIVDisease preventionSexual contactUse behaviorsChi-squarePrevalenceSyphilisDrugsVirusPrimary riskAn unrecognized key population? Traditional treatment practices associated with HIV risk among traditional healers in rural South Africa.
Audet CM, Ngobeni S, Mkansi M, Wafawanaka F, Aliyu MH, Vermund SH, Wagner RG. An unrecognized key population? Traditional treatment practices associated with HIV risk among traditional healers in rural South Africa. AIDS 2020, 34: 2313-2317. PMID: 33048882, PMCID: PMC7674239, DOI: 10.1097/qad.0000000000002710.Peer-Reviewed Original ResearchConceptsSkin incisionPatient's bloodHIV testTraditional healersHIV prevalenceKey populationsRapid HIV testsRisk of acquisitionHigh HIV prevalenceBlood-borne pathogensTraditional treatment practicesSouth African traditional healersPositive test resultsCross-sectional surveyPersonal protective equipmentHIV acquisitionHIV infectionPosttest counselingPretest counselingHIV riskOccupational exposureMAIN OUTCOMERural South AfricaHIVAfrican traditional healersCoinfection With HIV and SARS-CoV-2 in Wuhan, China: A 12-Person Case Series
Hu Y, Ma J, Huang H, Vermund SH. Coinfection With HIV and SARS-CoV-2 in Wuhan, China: A 12-Person Case Series. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2020, 85: 10.1097/qai.0000000000002424. PMID: 32568771, PMCID: PMC7446977, DOI: 10.1097/qai.0000000000002424.Peer-Reviewed Original ResearchConceptsAntiretroviral therapySARS-CoV-2Clinical improvementCase seriesLong-term antiretroviral therapyMild COVID-19 symptomsCOVID-19 coinfectionAcute COVID-19COVID-19 symptomsYears of ageCOVID-19Health care servicesPossible COVID-19 casesCoinfected PersonsAntiretroviral medicationsMedian ageIntensive careCOVID-19 casesClinical prognosisFavorable outcomeSevere symptomsAdditional casesCare servicesHIVInformed consentIntegrating and Interpreting Findings from the Latest Treatment as Prevention Trials
Brault MA, Spiegelman D, Abdool Karim SS, Vermund SH. Integrating and Interpreting Findings from the Latest Treatment as Prevention Trials. Current HIV/AIDS Reports 2020, 17: 249-258. PMID: 32297219, PMCID: PMC7260110, DOI: 10.1007/s11904-020-00492-4.Peer-Reviewed Original ResearchAssociation between stigma towards HIV and MSM and intimate partner violence among newly HIV-diagnosed Chinese men who have sex with men
Wang N, Huang B, Ruan Y, Amico KR, Vermund SH, Zheng S, Qian HZ. Association between stigma towards HIV and MSM and intimate partner violence among newly HIV-diagnosed Chinese men who have sex with men. BMC Public Health 2020, 20: 204. PMID: 32039716, PMCID: PMC7008577, DOI: 10.1186/s12889-020-8259-y.Peer-Reviewed Original ResearchConceptsIntimate partner violenceChinese MSMChinese menMultivariate logistic regression analysisLower stigmaRandomized clinical trialsLogistic regression analysisSexual intimate partner violenceHigh HIVClinical trialsHigh prevalenceHIV stigmaPartner violenceHIVMSMBaseline surveyVulnerable populationsMenRegression analysisPositive associationFace interviewsAssociationInfluence of IPVRisky behaviorsIPV experiences
2019
Interventions to improve the HIV continuum of care in China
Zhang X, Wang N, Vermund SH, Zou H, Li X, Zhang F, Qian HZ. Interventions to improve the HIV continuum of care in China. Current HIV/AIDS Reports 2019, 16: 448-457. PMID: 31776975, PMCID: PMC10767704, DOI: 10.1007/s11904-019-00469-y.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyHIV continuumHIV epidemicPublic health intervention programsFree ART programHIV sexual transmissionHIV testing campaignsFormer plasma donorsPurpose of ReviewToHealth intervention programsTwo-thirdsViral suppressionHeterosexual transmissionPediatric mortalitySexual transmissionRisk groupsMore infectionsPlasma donorsRecent FindingsTheIntervention programsYoung menCareHIVHeterosexual menLower ratesTreatment as Prevention: Concepts and Challenges for Reducing HIV Incidence
Brault MA, Spiegelman D, Hargreaves J, Nash D, Vermund SH. Treatment as Prevention: Concepts and Challenges for Reducing HIV Incidence. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2019, 82: s104-s112. PMID: 31658196, PMCID: PMC6820703, DOI: 10.1097/qai.0000000000002168.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyHIV transmissionHIV plasma loadReducing HIV IncidenceHIV prevention trialsCommunity-level interventionsDeployable vaccineViral suppressionHIV testingHIV incidencePrevention trialsUninfected personsChronic conditionsHIV investmentsEarly treatmentTreat strategySexual partnersViral expressionTransmission riskHIVTrialsTreatmentInconsistent findingsPreventionSaharan AfricaIncreasing male engagement in the prevention of vertical transmission of HIV: what works in sub-Saharan Africa?
Aliyu MH, Sam-Agudu NA, Shenoi S, Goga AE, Ramraj T, Vermund SH, Audet CM. Increasing male engagement in the prevention of vertical transmission of HIV: what works in sub-Saharan Africa? The BMJ 2019, 365: l1965. PMID: 31171558, PMCID: PMC6598674, DOI: 10.1136/bmj.l1965.Peer-Reviewed Original Research