2024
Nonadjuvanted Bivalent Respiratory Syncytial Virus Vaccination and Perinatal Outcomes
Son M, Riley L, Staniczenko A, Cron J, Yen S, Thomas C, Sholle E, Osborne L, Lipkind H. Nonadjuvanted Bivalent Respiratory Syncytial Virus Vaccination and Perinatal Outcomes. JAMA Network Open 2024, 7: e2419268. PMID: 38976271, PMCID: PMC11231799, DOI: 10.1001/jamanetworkopen.2024.19268.Peer-Reviewed Original ResearchConceptsRespiratory syncytial virusNeonatal intensive care unitPreterm birthWeeks gestationRisk of HDPPerinatal outcomesLogistic regression modelsIncreased riskPregnant individualsPrenatal vaccinationSmall-for-gestational age birth weightNeonatal intensive care unit admissionCohort studyIncreased risk of PTBOdds ratioIncreased risk of HDPRisk of preterm birthRespiratory syncytial virus seasonRespiratory syncytial virus vaccineRetrospective observational cohort studyNeonatal respiratory distressVaccination statusMultivariate logistic regression modelObservational cohort studyCox regression modelsCo-existing chronic hypertension and hypertensive disorders of pregnancy and associated adverse pregnancy outcomes
Sweeney L, Lundsberg L, Culhane J, Partridge C, Son M. Co-existing chronic hypertension and hypertensive disorders of pregnancy and associated adverse pregnancy outcomes. The Journal Of Maternal-Fetal & Neonatal Medicine 2024, 37: 2305675. PMID: 38290827, DOI: 10.1080/14767058.2024.2305675.Peer-Reviewed Original ResearchConceptsHypertensive disorders of pregnancyDisorders of pregnancyNeonatal outcomesChronic hypertensionHypertensive disordersIntensive care unitCesarean deliveryOdds of cesarean deliveryPregnant personsBlood pressureBivariate tests of associationHypertensive conditionsMaternal ICU admissionPreterm birth <Intensive care unit admissionAntihypertensive medication useBaseline clinical dataElectronic medical recordsTests of associationRetrospective cohort studySGA birthweightEligible peopleGestational ageMaternal comorbiditiesSingleton deliveries
2023
Severe maternal morbidity rates in a US-based electronic health record database, 2018–2022
Son M, Culhane J, Louis J, Handley S, Burris H, Greenspan J, McKenney K, Dysart K. Severe maternal morbidity rates in a US-based electronic health record database, 2018–2022. Journal Of Perinatology 2023, 43: 1316-1318. PMID: 37640810, DOI: 10.1038/s41372-023-01765-7.Peer-Reviewed Original ResearchThe association between a low 50-gram, 1-hour glucose challenge test value and neonatal morbidity
Ding J, Lundsberg L, Culhane J, Patridge C, Milley L, Son M. The association between a low 50-gram, 1-hour glucose challenge test value and neonatal morbidity. The Journal Of Maternal-Fetal & Neonatal Medicine 2023, 36: 2245527. PMID: 37558273, DOI: 10.1080/14767058.2023.2245527.Peer-Reviewed Original ResearchMeSH KeywordsBlood GlucoseDiabetes, GestationalFemaleGlucoseGlucose Tolerance TestHumansHypoglycemiaInfant, NewbornPregnancyPregnancy OutcomeRetrospective StudiesConceptsGlucose challenge test valuesTertiary care academic hospitalDiagnosis of GDMGlycemic screeningGCT valuesNICU admissionNeonatal outcomesMorbidity outcomesAcademic hospitalNeonatal intensive care unit admissionSingle tertiary care academic hospitalIntensive care unit admissionMultivariable logistic regression modelingComposite morbidity outcomeNeonatal morbidity outcomesCare unit admissionRetrospective cohort studyNewborns of mothersRisk of morbidityLogistic regression modelingEligible patientsUnit admissionAntenatal surveillanceGestational diabetesHypertensive disordersFetal growth restriction and small for gestational age as predictors of neonatal morbidity: which growth nomogram to use?
Leon-Martinez D, Lundsberg L, Culhane J, Zhang J, Son M, Reddy U. Fetal growth restriction and small for gestational age as predictors of neonatal morbidity: which growth nomogram to use? American Journal Of Obstetrics And Gynecology 2023, 229: 678.e1-678.e16. PMID: 37348779, DOI: 10.1016/j.ajog.2023.06.035.Peer-Reviewed Original ResearchConceptsNeonatal composite outcomeComposite outcomeFetal growth restrictionGestational ageFetal weightWeeks of gestationPositive likelihood ratioGrowth restrictionNonanomalous singleton pregnanciesPoor neonatal outcomeRetrospective cohort studySingle academic centerWeeks of deliveryDays of deliveryFetal growth referencesElectronic medical recordsProportion of fetusesLikelihood ratioNeonatal morbidityNeonatal outcomesPerinatal outcomesCohort studySingleton pregnanciesNeonatal dataMedical recordsLow-Dose Aspirin during Pregnancy and Postpartum Bleeding
White K, Son M, Lundsberg L, Culhane J, Partridge C, Reddy U, Merriam A. Low-Dose Aspirin during Pregnancy and Postpartum Bleeding. American Journal Of Perinatology 2023, 40: 1390-1397. PMID: 37211010, DOI: 10.1055/a-2096-5199.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnticoagulantsAspirinFemaleHumansPostpartum HemorrhagePostpartum PeriodPregnancyRetrospective StudiesConceptsLow-dose aspirinPostpartum blood lossTiming of discontinuationBlood lossPostpartum bleedingPostpartum hemorrhageLDA useUse of LDARed blood cell transfusionBlood cell transfusionRetrospective cohort studySystemic lupus erythematosusTime of deliveryDiagnosis of diabetesLogistic regression modelingElectronic medical recordsAspirin 81Ideal dosingPreeclampsia preventionCell transfusionDose aspirinCohort studyHypertensive diseaseLupus erythematosusPrimary outcomeAntibiotic choice for Group B Streptococcus prophylaxis in mothers with reported penicillin allergy and associated newborn outcomes
Snider J, Mithal L, Kwah J, Rhodes N, Son M. Antibiotic choice for Group B Streptococcus prophylaxis in mothers with reported penicillin allergy and associated newborn outcomes. BMC Pregnancy And Childbirth 2023, 23: 400. PMID: 37254067, PMCID: PMC10228028, DOI: 10.1186/s12884-023-05697-0.Peer-Reviewed Original ResearchConceptsGroup B streptococcus prophylaxisReported penicillin allergyPenicillin allergyGBS prophylaxisLab drawsNeonatal outcomesNewborn outcomesAntibiotic administrationMedical recordsPregnant individualsIntrapartum group B streptococcus prophylaxisNeonatal intensive care unit admissionDesignThis retrospective cohort studyIntensive care unit admissionSelf-reported penicillin allergyNeonates of mothersCare unit admissionIntrapartum antibiotic prophylaxisRetrospective cohort studyWeeks of gestationMother-infant pairsMother-infant dyadsBeta-lactam antibioticsAntibiotic prophylaxisUnit admissionIntravenous iron for treatment of iron deficiency anemia during pregnancy and associated maternal outcomes
Burn M, Lundsberg L, Culhane J, Partridge C, Son M. Intravenous iron for treatment of iron deficiency anemia during pregnancy and associated maternal outcomes. The Journal Of Maternal-Fetal & Neonatal Medicine 2023, 36: 2192855. PMID: 36958808, DOI: 10.1080/14767058.2023.2192855.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, IntravenousAnemiaAnemia, Iron-DeficiencyFemaleHumansInfant, NewbornIronPregnancyRetrospective StudiesConceptsIron deficiency anemiaMaternal morbidity compositeIntravenous ironMorbidity compositePotential confoundersElectronic medical recordsPregnant patientsTreatment courseDeficiency anemiaHigh-risk baseline characteristicsMultivariable logistic regression modellingRetrospective cohort studyFull treatment courseHospital electronic medical recordsIntensive care unitLogistic regression modellingGreater increaseMaternal morbidityMaternal outcomesNeonatal outcomesBaseline characteristicsCohort studyBlood transfusionPrimary outcomeTerm delivery
2022
Outpatient penicillin allergy evaluation during pregnancy and associated clinical outcomes
Kwah JH, Burn MS, Liao J, Cate J, Son M. Outpatient penicillin allergy evaluation during pregnancy and associated clinical outcomes. American Journal Of Obstetrics & Gynecology MFM 2022, 4: 100674. PMID: 35691578, DOI: 10.1016/j.ajogmf.2022.100674.Peer-Reviewed Original ResearchMeSH KeywordsAnti-Bacterial AgentsDrug HypersensitivityFemaleHumansInfant, NewbornOutpatientsPenicillinsPregnancyRetrospective StudiesConceptsPenicillin allergy evaluationPenicillin allergyPregnant womenAllergy evaluationHospital stayNeonatal outcomesClinical benefitIntensive care unit admissionBirth hospitalization lengthUnverified penicillin allergyCare unit admissionNeonatal adverse outcomesRetrospective cohort studyMedical record reviewPostpartum hospital stayAdditional clinical benefitLarge academic hospitalElectronic medical recordsBeta-lactam antibioticsPostpartum infectionReferred womenUnit admissionMaternal outcomesCohort studyTrue allergyPostpartum Length of Stay and Hospital Readmission Before and During the Coronavirus Disease 2019 (COVID-19) Pandemic
Handley SC, Gallagher K, Lindgren E, Lo JY, Burris HH, Dysart KC, Greenspan J, Culhane JF, Son M. Postpartum Length of Stay and Hospital Readmission Before and During the Coronavirus Disease 2019 (COVID-19) Pandemic. Obstetrics And Gynecology 2022, 139: 381-390. PMID: 35115443, DOI: 10.1097/aog.0000000000004687.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultCOVID-19FemaleHumansLength of StayPatient ReadmissionPostnatal CarePostpartum PeriodPregnancyRetrospective StudiesYoung AdultConceptsCoronavirus disease 2019 (COVID-19) pandemicObstetric patientsHospital readmissionMode of deliveryPostpartum hospitalizationDisease 2019 pandemicHospitalization dischargeCOVID-19 pandemicRetrospective cohort studyWeeks of gestationDays of deliveryLogistic mixed-effects modelsCohort studyHospitalization lengthSecondary outcomesPrimary outcomeAdjusted analysisStudy cohortVaginal birthCesarean birthReadmissionPostpartum lengthPatientsHospitalizationMixed-effects models
2021
Birth Hospital Length of Stay and Rehospitalization During COVID-19
Handley SC, Gallagher K, Breden A, Lindgren E, Lo JY, Son M, Murosko D, Dysart K, Lorch SA, Greenspan J, Culhane JF, Burris HH. Birth Hospital Length of Stay and Rehospitalization During COVID-19. Pediatrics 2021, 149: e2021053498. PMID: 34889449, PMCID: PMC9645693, DOI: 10.1542/peds.2021-053498.Peer-Reviewed Original ResearchMeSH KeywordsCOVID-19FemaleHumansInfant, NewbornLength of StayMalePatient ReadmissionPractice Patterns, Physicians'PregnancyRetrospective StudiesTerm BirthUnited StatesConceptsInfant rehospitalizationAdjusted odds ratioTerm infantsBirth hospitalization dischargeBirth hospitalization lengthHealthy term infantsRetrospective cohort studyCoronavirus disease 2019 eraDay of birthCOVID-19Hospitalization dischargePrepandemic eraHospital lengthMultivariable adjustmentCohort studyHospitalization lengthShorter LOSAdjusted analysisOdds ratioRehospitalizationInfantsHealth systemAdditional outcomesCOVID-19 eraMixed effects modelsDuration of Exposure to General Endotracheal Anesthesia during Cesarean Deliveries at Term and Perinatal Complications
Swanson K, Liang L, Grobman WA, Higgins N, Roy A, Son M. Duration of Exposure to General Endotracheal Anesthesia during Cesarean Deliveries at Term and Perinatal Complications. American Journal Of Perinatology 2021, 39: 232-237. PMID: 34844279, DOI: 10.1055/s-0041-1739355.Peer-Reviewed Original ResearchConceptsGeneral endotracheal anesthesiaPrimary perinatal outcomeCesarean deliveryPerinatal complicationsPerinatal outcomesDuration of exposureMaternal morbidityMultivariable analysisGeneral anesthesiaEndotracheal anesthesiaFetal statusSingle tertiary care centerComposite of complicationsPrior abdominal surgeryTertiary care centerWeeks of gestationMaternal complicationsNonanomalous gestationsApgar scoreMultivariable adjustmentSecondary outcomesAbdominal surgeryBivariable analysisRetrospective studyCare centerCoronavirus Disease 2019 (COVID-19) Pandemic and Pregnancy Outcomes in a U.S. Population
Son M, Gallagher K, Lo JY, Lindgren E, Burris HH, Dysart K, Greenspan J, Culhane JF, Handley SC. Coronavirus Disease 2019 (COVID-19) Pandemic and Pregnancy Outcomes in a U.S. Population. Obstetrics And Gynecology 2021, 138: 542-551. PMID: 34433180, PMCID: PMC8454282, DOI: 10.1097/aog.0000000000004547.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 infectionAdverse pregnancy-related outcomesPregnancy-related outcomesCoronavirus disease 2019 (COVID-19) pandemicDisease 2019 pandemicPregnancy outcomesGestational ageSARS-CoV-2 testingDiverse U.S. cohortAdverse pregnancy outcomesRetrospective cohort studyPositive test resultsSARS-CoV-2 diagnosisSignificant differencesNegative test resultsHypertensive disordersPlacental abruptionBaseline characteristicsCohort studyPreterm birthPostpartum hemorrhagePregnant womenCesarean birthU.S. cohortPublic insuranceA Multivariable Predictive Model for Success of External Cephalic Version
Dahl CM, Zhang Y, Ong JX, Yeh C, Son M, Miller ES, Roy A, Grobman WA. A Multivariable Predictive Model for Success of External Cephalic Version. Obstetrics And Gynecology 2021, 138: 426-433. PMID: 34352823, DOI: 10.1097/aog.0000000000004518.Peer-Reviewed Original ResearchConceptsBody mass indexFetal malpresentationPlacental locationECV successECV attemptPatient characteristicsFetal weightMaternal ageSingle quaternary care hospitalMultivariable logistic regression modelExternal cephalic versionExternal cephalic version successQuaternary care hospitalMultivariable predictive modelAmniotic fluid volumeYears of ageLogistic regression modelsObjective patient characteristicsHigh discriminatory capacitySingleton gestationsCare hospitalGestational agePatient factorsMass indexCephalic versionPatient characteristics associated with complications of external cephalic version
Dahl CM, Zhang Y, Ong JX, Yeh C, Son M, Miller ES, Roy A, Grobman WA. Patient characteristics associated with complications of external cephalic version. American Journal Of Obstetrics & Gynecology MFM 2021, 3: 100411. PMID: 34058425, DOI: 10.1016/j.ajogmf.2021.100411.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBreech PresentationCesarean SectionFemaleHumansInfant, NewbornPlacentaPregnancyRetrospective StudiesVersion, FetalConceptsExternal cephalic versionBody mass indexPatient characteristicsCephalic versionPlacental locationGestational ageFetal weightMass indexCord prolapsePlacental abruptionFetal statusSpontaneous ruptureIntensive care unit admissionSingle quaternary care centerHigher body mass indexExternal cephalic version attemptAnterior placental locationNonreassuring fetal statusUmbilical cord prolapseCare unit admissionCord arterial pHGreater gestational ageMultivariable logistic regressionQuaternary care centerExternal cephalic version success
2018
Maternal Obstetric Complication Rates Remain High in Illinois: A Retrospective Study, 2010–2015
Roy A, Peaceman A, Son M, Feinglass J. Maternal Obstetric Complication Rates Remain High in Illinois: A Retrospective Study, 2010–2015. The Joint Commission Journal On Quality And Patient Safety 2018, 45: 24-30. PMID: 30121161, DOI: 10.1016/j.jcjq.2018.02.007.Peer-Reviewed Original ResearchConceptsSevere maternal morbidityMaternal morbidityMaternal complicationsCesarean deliveryDelivery complicationsComplication rateSevere maternal morbidity ratesStudy periodMaternal complication ratesMaternal morbidity ratesMaternal obstetric complicationsObstetric complication ratesObstetrics residency programsRetrospective cohort studyNinth Revision codesObstetric complicationsClinical characteristicsCohort studyPatient characteristicsChildbirth outcomesMorbidity ratePreventable complicationsRevision codesIllinois HospitalMorbidityAssociation Between Attempted External Cephalic Version and Perinatal Morbidity and Mortality
Son M, Roy A, Grobman WA, Miller ES. Association Between Attempted External Cephalic Version and Perinatal Morbidity and Mortality. Obstetrics And Gynecology 2018, 132: 365-370. PMID: 29995733, PMCID: PMC6060011, DOI: 10.1097/aog.0000000000002699.Peer-Reviewed Original ResearchConceptsNeonatal intensive care unit admissionIntensive care unit admissionComposite perinatal morbidityCare unit admissionPerinatal morbidityECV attemptWeeks of gestationUnit admissionMortality outcomesNeonatal anemiaLower mean body mass indexMean body mass indexExternal cephalic version attemptNeonatal therapeutic hypothermiaNonanomalous singleton gestationsRetrospective cohort studyTertiary care institutionBody mass indexExternal cephalic versionNonvertex presentationExpectant managementCohort studyFetal malpresentationSecondary outcomesSingleton gestations
2017
Attempted operative vaginal delivery vs repeat cesarean in the second stage among women undergoing a trial of labor after cesarean delivery
Son M, Roy A, Grobman WA. Attempted operative vaginal delivery vs repeat cesarean in the second stage among women undergoing a trial of labor after cesarean delivery. American Journal Of Obstetrics And Gynecology 2017, 216: 407.e1-407.e5. PMID: 28153660, DOI: 10.1016/j.ajog.2017.01.013.Peer-Reviewed Original ResearchConceptsTrial of laborOperative vaginal deliveryRepeat cesarean deliveryVaginal delivery attemptFrequency of endometritisCesarean deliveryVaginal deliverySecond-stage laborNeonatal outcomesFetal stationHuman Development Maternal-Fetal Medicine Units NetworkMaternal-Fetal Medicine Units NetworkLower mean body mass indexMean body mass indexEunice Kennedy Shriver National InstituteNon-Hispanic black raceNeonatal adverse outcomesPrevious vaginal deliverySpontaneous vaginal deliveryBody mass indexRetrospective secondary analysisCesarean RegistryNeonatal complicationsNonanomalous gestationsCephalic presentation
2016
The association between intrauterine balloon tamponade duration and postpartum hemorrhage outcomes
Einerson BD, Son M, Schneider P, Fields I, Miller ES. The association between intrauterine balloon tamponade duration and postpartum hemorrhage outcomes. American Journal Of Obstetrics And Gynecology 2016, 216: 300.e1-300.e5. PMID: 27823918, DOI: 10.1016/j.ajog.2016.10.040.Peer-Reviewed Original ResearchConceptsIntrauterine balloon tamponadeIntensive care unit admissionCare unit admissionBlood product transfusionBalloon tamponadePostpartum feverPostpartum hemorrhageTamponade durationUnit admissionHospital lengthProduct transfusionBlood lossClinical outcomesMaternal intensive care unit admissionPacked red blood cellsMultivariable logistic regression modelHemorrhage-related outcomesMean hospital lengthRetrospective cohort studyFirst-line treatmentUterine artery embolizationLength of stayLack of associationLogistic regression modelsArtery embolizationAssociation among Maternal Obesity, Cervical Length, and Preterm Birth
Palatnik A, Miller ES, Son M, Kominiarek MA. Association among Maternal Obesity, Cervical Length, and Preterm Birth. American Journal Of Perinatology 2016, 34: 471-479. PMID: 27704492, PMCID: PMC7189342, DOI: 10.1055/s-0036-1593350.Peer-Reviewed Original ResearchConceptsSpontaneous preterm birthBody mass indexMid-trimester cervical lengthCervical lengthHigh BMI groupBMI groupsPreterm birthMaternal body mass indexPrior spontaneous preterm birthHigher body mass indexLong cervical lengthCervical length assessmentPotential protective effectMaternal obesityRetrospective cohortSingleton pregnanciesMass indexMultivariable analysisUnivariable analysisDecreased riskProtective effectMultivariable regressionGroup 2Length assessmentWeeks