2024
Late-Onset Postpartum Hypertension After Normotensive Pregnancy.
Sinnott C, Lundsberg L, Culhane J, Partridge C, Denoble A. Late-Onset Postpartum Hypertension After Normotensive Pregnancy. Obstetrics And Gynecology 2024 PMID: 39361961, DOI: 10.1097/aog.0000000000005751.Peer-Reviewed Original ResearchMonths postpartumAcademic health care systemHealth care systemElectronic medical recordsPostpartum carePrimary careRetrospective cohort studyBlood pressureCare systemEvidence of hypertensionWeeks postpartumPostpartum periodCohort studyPostpartum hypertensionPostpartumAmerican CollegeImmediately postpartumMedical recordsAssociation criteriaCareNormotensive pregnanciesBP abnormalitiesNormotensive cohortLate-onsetPregnancyCoronavirus Disease 2019 (COVID-19) Vaccination and Stillbirth in the Vaccine Safety Datalink
Denoble A, Vazquez-Benitez G, Sheth S, Ackerman-Banks C, DeSilva M, Zhu J, Daley M, Getahun D, Klein N, Vesco K, Irving S, Nelson J, Williams J, Hambidge S, Donahue J, Weintraub E, Kharbanda E, Lipkind H. Coronavirus Disease 2019 (COVID-19) Vaccination and Stillbirth in the Vaccine Safety Datalink. Obstetrics And Gynecology 2024, 144: 215-222. PMID: 38843526, PMCID: PMC11250101, DOI: 10.1097/aog.0000000000005632.Peer-Reviewed Original ResearchVaccine Safety DatalinkAntepartum stillbirthVaccine Safety Datalink sitesLive birthsCOVID-19 vaccineVaccine dosePregnancy start dateRisk of severe morbidityRisk of stillbirthConditional logistic regressionCase-control studyVaccine manufacturersSingleton pregnanciesGestational ageFetal deathPostpartum visitMaternal ageIndex dateSevere morbidityDiagnostic codesPregnancyStillbirthPregnant peopleCOVID-19Logistic regressionObstetric Complications and Birth Outcomes After Antenatal Coronavirus Disease 2019 (COVID-19) Vaccination
Vesco K, Denoble A, Lipkind H, Kharbanda E, DeSilva M, Daley M, Getahun D, Zerbo O, Naleway A, Jackson L, Williams J, Boyce T, Fuller C, Weintraub E, Vazquez-Benitez G. Obstetric Complications and Birth Outcomes After Antenatal Coronavirus Disease 2019 (COVID-19) Vaccination. Obstetrics And Gynecology 2024, 143: 794-802. PMID: 38626447, PMCID: PMC11090513, DOI: 10.1097/aog.0000000000005583.Peer-Reviewed Original ResearchConceptsSmall-for-gestational ageMessenger RNA COVID-19 vaccineGestational diabetes mellitusRisk of adverse pregnancy outcomesAdverse pregnancy outcomesPreterm birthGestational hypertensionAdjusted hazard ratiosCOVID-19 vaccine dosesPregnancy outcomesCOVID-19 vaccineAssociated with small-for-gestational ageIncreased risk of adverse pregnancy outcomesVaccine doseRisk of preterm birthMessenger RNARetrospective cohort study of individualsMRNA COVID-19 vaccineWeeks of gestationRetrospective cohort studyHistory of COVID-19Cohort study of individualsVaccine Safety DatalinkSingleton pregnanciesUnexposed pregnanciesAbnormal uterine bleeding diagnoses and care following COVID-19 vaccination
Brooks N, Irving S, Kauffman T, Vesco K, Slaughter M, Smith N, Tepper N, Olson C, Weintraub E, Naleway A, Group V, DeNoble A, DeSilva M, Ellington S, Henninger M, Jazwa A, Kharbanda E, Lipkind H, Malden D, McNeil M, Tartof S, Zerbo O. Abnormal uterine bleeding diagnoses and care following COVID-19 vaccination. American Journal Of Obstetrics And Gynecology 2024, 230: 540.e1-540.e13. PMID: 38219855, DOI: 10.1016/j.ajog.2024.01.006.Peer-Reviewed Original ResearchAUB diagnosisAbnormal uterine bleedingAbnormal uterine bleeding casesUterine bleedingBleeding diagnosisAbnormal bleedingCOVID-19 vaccineChart reviewVaccinated patientsBleeding casesHealth system membersVaccination statusFemale patients of reproductive ageComparison of clinical characteristicsChart review of patientsPatients of reproductive ageProportion of Asian patientsDays of COVID-19 vaccinationReview of patientsVolume of bleedingProportion of patientsDemographic characteristics of patientsPost-COVID-19 vaccinationCharacteristics of patientsRace of patientsRate of clinically significant red blood cell antibody seroconversion in pregnancy
Ding J, Abels E, Jacobs J, Culhane J, Lundsberg L, Partridge C, Denoble A, Kohari K. Rate of clinically significant red blood cell antibody seroconversion in pregnancy. The Journal Of Maternal-Fetal & Neonatal Medicine 2024, 37: 2419370. PMID: 39462637, DOI: 10.1080/14767058.2024.2419370.Peer-Reviewed Original ResearchConceptsNeonatal intensive care unitAdvanced maternal ageAssociated with seroconversionClinically significant antibodiesAntibody screeningNeonatal outcomesIncreasing gravidityAntibody seroconversionInitial hemoglobinMaternal ageSignificant antibodiesAntibody statusNeonatal intensive care unit admissionCohort studyClinically significant RBC antibodiesAnti-CUnexplained fetal lossPositive antibody screenNegative antibody screenCases of stillbirthRetrospective cohort studyIntensive care unitWilcoxon rank-sumMaternal antibody statusPostnatal transfusion715 Trends in Tdap and Flu Vaccination in Pregnant People in Relation to the COVID-19 Pandemic
Dave E, Culhane J, Lundsberg L, Partridge C, Kohari K, Denoble A. 715 Trends in Tdap and Flu Vaccination in Pregnant People in Relation to the COVID-19 Pandemic. American Journal Of Obstetrics And Gynecology 2024, 230: s382. DOI: 10.1016/j.ajog.2023.11.741.Peer-Reviewed Original Research597 De novo hypertension in the late postpartum period: a case for extending postpartum care
Sinnott C, Stammler S, Lundsberg L, Partridge C, Culhane J, Denoble A. 597 De novo hypertension in the late postpartum period: a case for extending postpartum care. American Journal Of Obstetrics And Gynecology 2024, 230: s323-s324. DOI: 10.1016/j.ajog.2023.11.622.Peer-Reviewed Original Research601 Evolution of hypertension stages in pregnancy and postpartum from 2013-2022
Stammler S, Denoble A, Culhane J, Lundsberg L, Partridge C. 601 Evolution of hypertension stages in pregnancy and postpartum from 2013-2022. American Journal Of Obstetrics And Gynecology 2024, 230: s325-s326. DOI: 10.1016/j.ajog.2023.11.626.Peer-Reviewed Original Research425 Effect of the COVID-19 pandemic on population-level mean arterial pressure during pregnancy and postpartum
Denoble A, Stammler S, Partridge C, Lundsberg L, Culhane J. 425 Effect of the COVID-19 pandemic on population-level mean arterial pressure during pregnancy and postpartum. American Journal Of Obstetrics And Gynecology 2024, 230: s235. DOI: 10.1016/j.ajog.2023.11.451.Peer-Reviewed Original Research426 Brain natriuretic peptide testing and severe maternal morbidity in pregnancies affected by heart disease
Denoble A, Federspiel J, Goldstein S, Culhane J, Dysart K. 426 Brain natriuretic peptide testing and severe maternal morbidity in pregnancies affected by heart disease. American Journal Of Obstetrics And Gynecology 2024, 230: s235-s236. DOI: 10.1016/j.ajog.2023.11.452.Peer-Reviewed Original ResearchUrinary Tract Infection and Progression to Pyelonephritis: Group B Streptococcus versus E. coli
Sachdeva S, Rosett H, Krischak M, Weaver K, Heine R, Denoble A, Dotters-Katz S. Urinary Tract Infection and Progression to Pyelonephritis: Group B Streptococcus versus E. coli. American Journal Of Perinatology Reports 2024, 14: e80-e84. PMID: 38370326, PMCID: PMC10874690, DOI: 10.1055/s-0044-1779031.Peer-Reviewed Original ResearchLower urinary tract infectionsLow birth weightUrinary tract infectionHistory of ACLength of stayPreterm deliveryGestational agePreterm birthTract infectionsPregnant womenRetrospective cohort of pregnant womenGroup B <i>Streptococcus</i> (GBPrimary outcomeHistory of preterm birthMedical records of womenCohort of pregnant womenLow birth weight rateAssociated with severe infectionsMedian gestational ageMedian length of stayGroup B streptococciLower urinary tractRecords of womenPrimary infection typeMedian GA
2023
Maternal and Pregnancy Outcomes Following Heart Transplantation in the United States
Craig A, Campbell A, Snow S, Spates T, Goldstein S, Denoble A, Meng M, Schroder J, Flores K, Agarwal R, Ward C, Federspiel J. Maternal and Pregnancy Outcomes Following Heart Transplantation in the United States. JACC Heart Failure 2023, 11: 1666-1674. PMID: 37804312, PMCID: PMC10841668, DOI: 10.1016/j.jchf.2023.08.018.Peer-Reviewed Original ResearchNontransfusion severe maternal morbiditySevere maternal morbidityHT recipientsHeart transplantationPreterm birthDelivery hospitalizationsGreater oddsPregnancy outcomesRate of SMMNationwide Readmissions DatabaseOutcome of pregnancyHigher readmission ratesProportional hazards regressionHigh morbidity rateMaternal morbidityReadmission ratesHospital readmissionAdjusted analysisComorbid conditionsClinical comorbiditiesHazards regressionMorbidity rateHigh riskHT historyDays postpartumEP21.03: Volume of chorionic villus sampling and delay in patient care
Lee E, Wu Y, Denoble A, Wong J, Kohari K, Copel J. EP21.03: Volume of chorionic villus sampling and delay in patient care. Ultrasound In Obstetrics And Gynecology 2023, 62: 239-240. DOI: 10.1002/uog.27024.Peer-Reviewed Original ResearchEP21.07: Impact of patient obesity on chorionic villus sampling volume outcomes
Lee E, Wu Y, Denoble A, Wong J, Kohari K, Copel J. EP21.07: Impact of patient obesity on chorionic villus sampling volume outcomes. Ultrasound In Obstetrics And Gynecology 2023, 62: 241-241. DOI: 10.1002/uog.27028.Peer-Reviewed Original ResearchHypertension Screening in Pregnancy
Denoble A, Pettker C. Hypertension Screening in Pregnancy. JAMA 2023, 330: 1040-1041. PMID: 37721621, DOI: 10.1001/jama.2023.15088.Commentaries, Editorials and LettersAssociations between Anemia and Outcomes of Pregnant Patients with Pyelonephritis
Cunningham H, Knochenhauer H, Federspiel J, Wein L, Denoble A, Heine R, Dotters-Katz S. Associations between Anemia and Outcomes of Pregnant Patients with Pyelonephritis. American Journal Of Perinatology 2023, 41: e2403-e2409. PMID: 37339672, PMCID: PMC10799185, DOI: 10.1055/a-2113-2892.Peer-Reviewed Original ResearchSevere maternal morbidityNationwide Readmissions DatabaseMaternal morbidityPregnant patientsAcute respiratory distress syndromeAdverse maternal outcomesLonger hospital stayAcute renal failureDisease Control criteriaRetrospective cohort studyRespiratory distress syndromeWeighted national estimateComplex survey methodsMaternal comorbiditiesNonanemic patientsHospital stayMaternal outcomesBaseline characteristicsRenal failureCohort studyDistress syndromePrimary outcomeSepsis riskAnemic patientsClinical comorbidities1184-P: No Increased Risk of Gestational Diabetes Mellitus (GDM) Diagnosis after COVID-19 Vaccination
VESCO K, DENOBLE A, LIPKIND H, KHARBANDA E, DESILVA M, DALEY M, GETAHUN D, ZERBO O, NALEWAY A, JACKSON L, WILLIAMS J, BOYCE T, FULLER C, VAZQUEZ BENITEZ G. 1184-P: No Increased Risk of Gestational Diabetes Mellitus (GDM) Diagnosis after COVID-19 Vaccination. Diabetes 2023, 72 DOI: 10.2337/db23-1184-p.Peer-Reviewed Original ResearchCOVID-19 vaccinationCOVID-19 vaccineRisk of GDMCOVID-19 vaccine dosesNon-Hispanic whitesGDM diagnosisVaccine dosesDisease controlGestational diabetes mellitus diagnosisDe novo diabetesRate of GDMDiagnosis of GDMVaccine Safety DatalinkPfizer Inc.Confidence intervalsICD-10 codesNon-Hispanic blacksDiabetes mellitus diagnosisOutcomes Research InstituteNon-Hispanic AsiansHealth care systemNonpregnant adultsUnvaccinated individualsIncreased riskRelative riskAntihypertensives in Pregnancy
Denoble A, Goldstein S, Pettker C. Antihypertensives in Pregnancy. Obstetrics And Gynecology Clinics Of North America 2023, 50: 39-78. PMID: 36822710, DOI: 10.1016/j.ogc.2022.10.008.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsSignificant maternal morbidityTreatment of hypertensionAmniotic fluid volumeHypertensive disordersMaternal morbidityPregnant patientsFetal growthCurrent guidelinesEfficacy dataAvailable safetyPregnancyAntihypertensivesFluid volumeClose supervisionHypertensionMorbidityPatientsPostpartumMortalityAvailable dataDiagnosisMaternal and pregnancy outcomes following heart transplantation in the United States
Craig A, Campbell A, Snow S, Denoble A, Agarwal R, Ward C, Federspiel J. Maternal and pregnancy outcomes following heart transplantation in the United States. American Journal Of Obstetrics And Gynecology 2023, 228: s427-s428. DOI: 10.1016/j.ajog.2022.11.742.Peer-Reviewed Original Research
2022
Prospective Observational Study of N-terminal Pro–Brain Natriuretic Peptide Levels in Obese and Nonobese Women during Pregnancy
Denoble A, Moyett J, Goldstein S, Ward CC, Truong T, Erkanli A, James A, Grotegut C. Prospective Observational Study of N-terminal Pro–Brain Natriuretic Peptide Levels in Obese and Nonobese Women during Pregnancy. American Journal Of Perinatology 2022, 40: 467-474. PMID: 35973801, PMCID: PMC10168705, DOI: 10.1055/a-1925-1532.Peer-Reviewed Original ResearchConceptsNT-proBNP levelsBody mass indexProspective observational studyObese patientsNonobese patientsNT-proBNPWeeks postpartumObservational studyN-terminal pro-brain natriuretic peptide levelsN-terminal pro-brain natriuretic peptidePro-brain natriuretic peptide levelsLinear mixed effects modelsLower NT-proBNP levelsHigher systolic blood pressurePro-brain natriuretic peptidePregnant peopleNatriuretic peptide levelsSignificant medical comorbiditiesTime pointsSystolic blood pressureMixed effects modelsEffects modelLogNT-proBNPPP elevationHypertensive disorders