2024
Obstetric Complications and Birth Outcomes After Antenatal Coronavirus Disease 2019 (COVID-19) Vaccination
Vesco K, Denoble A, Lipkind H, Kharbanda E, DeSilva M, Daley M, Getahun D, Zerbo O, Naleway A, Jackson L, Williams J, Boyce T, Fuller C, Weintraub E, Vazquez-Benitez G. Obstetric Complications and Birth Outcomes After Antenatal Coronavirus Disease 2019 (COVID-19) Vaccination. Obstetrics And Gynecology 2024, 143: 794-802. PMID: 38626447, PMCID: PMC11090513, DOI: 10.1097/aog.0000000000005583.Peer-Reviewed Original ResearchConceptsSmall-for-gestational ageMessenger RNA COVID-19 vaccineGestational diabetes mellitusRisk of adverse pregnancy outcomesAdverse pregnancy outcomesPreterm birthGestational hypertensionAdjusted hazard ratiosCOVID-19 vaccine dosesPregnancy outcomesCOVID-19 vaccineAssociated with small-for-gestational ageIncreased risk of adverse pregnancy outcomesVaccine doseRisk of preterm birthMessenger RNARetrospective cohort study of individualsMRNA COVID-19 vaccineWeeks of gestationRetrospective cohort studyHistory of COVID-19Cohort study of individualsVaccine Safety DatalinkSingleton pregnanciesUnexposed pregnanciesRate of clinically significant red blood cell antibody seroconversion in pregnancy
Ding J, Abels E, Jacobs J, Culhane J, Lundsberg L, Partridge C, Denoble A, Kohari K. Rate of clinically significant red blood cell antibody seroconversion in pregnancy. The Journal Of Maternal-Fetal & Neonatal Medicine 2024, 37: 2419370. PMID: 39462637, DOI: 10.1080/14767058.2024.2419370.Peer-Reviewed Original ResearchMeSH KeywordsAdultErythrocytesFemaleHumansInfant, NewbornIsoantibodiesPregnancyPregnancy OutcomeRetrospective StudiesRisk FactorsSeroconversionConceptsNeonatal intensive care unitAdvanced maternal ageAssociated with seroconversionClinically significant antibodiesAntibody screeningNeonatal outcomesIncreasing gravidityAntibody seroconversionInitial hemoglobinMaternal ageSignificant antibodiesAntibody statusNeonatal intensive care unit admissionCohort studyClinically significant RBC antibodiesAnti-CUnexplained fetal lossPositive antibody screenNegative antibody screenCases of stillbirthRetrospective cohort studyIntensive care unitWilcoxon rank-sumMaternal antibody statusPostnatal transfusion
2022
Comparison of severe maternal morbidity in pregnancy by modified World Health Organization Classification of maternal cardiovascular risk
Denoble AE, Goldstein SA, Wein LE, Grotegut CA, Federspiel JJ. Comparison of severe maternal morbidity in pregnancy by modified World Health Organization Classification of maternal cardiovascular risk. American Heart Journal 2022, 250: 11-22. PMID: 35526569, PMCID: PMC9836743, DOI: 10.1016/j.ahj.2022.04.009.Peer-Reviewed Original ResearchMeSH KeywordsCardiovascular DiseasesFemaleHeart Disease Risk FactorsHumansMorbidityPregnancyRetrospective StudiesRisk FactorsWorld Health OrganizationConceptsSevere maternal morbidityWorld Health Organization classificationDelivery hospitalizationsCardiac diagnosisMaternal morbidityOrganization classificationMaternal cardiovascular riskNationwide Readmissions DatabaseRisk of deathSevere cardiac diseaseWeighted national estimateMWHO classificationDelivery admissionCardiovascular riskPregnant patientsSecondary outcomesPrimary outcomeRetrospective studyYear postpartumPregnancy counselingPrimary exposureMonths postpartumNationwide databaseCardiac diseaseElevated risk
2021
Pregnancy Outcomes among Women with Class III Obesity with Pre-diabetic Early Hemoglobin A1C
Dillon J, Mitchell CJ, Ellett T, Siegel A, Denoble AE, Dotters-Katz SK. Pregnancy Outcomes among Women with Class III Obesity with Pre-diabetic Early Hemoglobin A1C. American Journal Of Perinatology 2021, 39: 238-242. PMID: 34891200, DOI: 10.1055/s-0041-1739358.Peer-Reviewed Original ResearchConceptsGestational diabetes mellitusClass III obesityBody mass indexPre-diabetic rangeGestational diabetesA1C 5.7Normal A1CPrimary outcomeGestational ageDevelopment of GDMClass III obese womenDelivery body mass indexNon-anomalous singleton pregnanciesMaternal body mass indexLow-A1C groupFetal growth restrictionInduction of laborHigh-risk populationA1c groupMedian A1CPregnancy complicationsBaseline demographicsCesarean deliveryMultiple gestationsObese womenManagement of Cerclage in Patients With Preterm Prelabor Rupture of Membranes
Wu J, Denoble AE, Kuller JA, Dotters-Katz SK. Management of Cerclage in Patients With Preterm Prelabor Rupture of Membranes. Obstetrical & Gynecological Survey 2021, 76: 681-691. PMID: 34854925, DOI: 10.1097/ogx.0000000000000957.Peer-Reviewed Original ResearchMeSH KeywordsCerclage, CervicalChorioamnionitisFemaleFetal Membranes, Premature RuptureHumansInfant, NewbornPregnancyPregnancy OutcomeRetrospective StudiesConceptsMaternal infectious morbidityPreterm prelabor ruptureCerclage removalCervical cerclageInfectious morbidityNeonatal outcomesPrelabor ruptureNeonatal morbidity outcomesRetention of cerclageSetting of PPROMTime of PPROMTime of diagnosisCerclage placementCerclage retentionLatency antibioticsNeonatal complicationsCorticosteroid administrationMaternal morbidityPreterm laborNeonatal sepsisMorbidity outcomesNeonatal mortalityRetrospective natureDefinitive benefitPPROMPregnancy outcomes among women with class III obesity with normal early glucola
Ellett T, Mitchell CJ, Dillon J, Siegel A, Denoble AE, Dotters-Katz S. Pregnancy outcomes among women with class III obesity with normal early glucola. The Journal Of Maternal-Fetal & Neonatal Medicine 2021, 35: 5834-5839. PMID: 33818267, DOI: 10.1080/14767058.2021.1895741.Peer-Reviewed Original ResearchMeSH KeywordsDiabetes, GestationalFemaleFetal MacrosomiaGlucoseHumansInfant, NewbornObesityPregnancyPregnancy OutcomeRetrospective StudiesWeight GainConceptsBody mass indexRate of GDMGlucose challenge testGestational diabetesObese womenPrimary outcomeGestational ageChallenge testDelivery body mass indexNon-anomalous singleton pregnanciesMaternal body mass indexOral glucose challenge testClass 3 obesityDevelopment of GDMClass III obesityGestational diabetes mellitusFetal growth restrictionInduction of laborNeonatal birthweightPregnancy complicationsBaseline demographicsCesarean deliveryMultiple gestationsPregnancy outcomesRetrospective cohort
2020
Lower Urinary Pathogens: Do More Pathogenic Bacteria Increase the Risk of Pyelonephritis?
Rosett HA, Krischak MK, Sachdeva S, Weaver KE, Heine RP, Denoble AE, Dotters-Katz SK. Lower Urinary Pathogens: Do More Pathogenic Bacteria Increase the Risk of Pyelonephritis? American Journal Of Perinatology 2020, 39: 473-478. PMID: 32971563, DOI: 10.1055/s-0040-1717093.Peer-Reviewed Original ResearchConceptsLower urinary tract infectionsHistory of preeclampsiaPreterm birthPregnant womenLow birthweightPathogenic infectionsOutside of pregnancyRisk of pyelonephritisOdds of progressionSingle tertiary centerPreterm birth rateRisk of progressionUrinary tract infectionBody mass indexRate of progressionHistory of pyelonephritisAsymptomatic bacteriuriaChronic hypertensionMedian LOSObstetric outcomesUrinary culturePostpartum dataRetrospective cohortSecondary outcomesTract infectionsUsing the new definition of intraamniotic infection – is there morbidity among the women left out?
Smith MM, Daifotis HA, DeNoble AE, Dotters-Katz SK. Using the new definition of intraamniotic infection – is there morbidity among the women left out? The Journal Of Maternal-Fetal & Neonatal Medicine 2020, 34: 4148-4152. PMID: 31928262, DOI: 10.1080/14767058.2020.1711723.Peer-Reviewed Original ResearchMeSH KeywordsChorioamnionitisEndometritisFemaleHumansMorbidityPregnancyPuerperal InfectionRetrospective StudiesConceptsPostpartum infectionIntraamniotic infectionPrimary outcomePostpartum infectious morbidityUrinary tract infectionSingle academic centerFourth-degree lacerationsBackward stepwise eliminationACOG criteriaAntibiotic receiptGestational hypertensionIntrapartum characteristicsMaternal feverMaternal tachycardiaDegree lacerationsInfectious morbidityRetrospective cohortTract infectionsDiagnostic criteriaAcademic centersInfectionWomenBivariate statisticsMorbidityFever
2019
Factors Associated with Utilization of 17-Hydroxyprogesterone Caproate for the Prevention of Recurrent Preterm Birth
DeNoble AE, Wynn CE, Weaver KE, Wheeler SM, Swamy GK. Factors Associated with Utilization of 17-Hydroxyprogesterone Caproate for the Prevention of Recurrent Preterm Birth. American Journal Of Perinatology 2019, 37: 264-270. PMID: 30708392, DOI: 10.1055/s-0039-1678532.Peer-Reviewed Original ResearchConceptsSpontaneous preterm birthPrior term birthPrenatal care initiationEligible womenPreterm birthPrimary outcomeTerm birthsWeeks' gestationCare initiationHispanic ethnicityRecurrent spontaneous preterm birthSingleton spontaneous preterm birthPrior spontaneous preterm birthRecurrent preterm birthRetrospective cohort studyAcademic health systemStepwise logistic regressionSPTB rateCohort studyEligible subjectsSingleton pregnanciesClinical predictorsPoor adherenceMaternal ageCare barriersBeyond the Window: Patient Characteristics and Geographic Locations Associated with Late Prenatal Care in Women Eligible for 17-P Preterm Birth Prevention
Wheeler S, DeNoble A, Wynn C, Weaver K, Swamy G, Janko M, Lantos P. Beyond the Window: Patient Characteristics and Geographic Locations Associated with Late Prenatal Care in Women Eligible for 17-P Preterm Birth Prevention. Journal Of Racial And Ethnic Health Disparities 2019, 6: 563-569. PMID: 30632084, DOI: 10.1007/s40615-018-00555-8.Peer-Reviewed Original ResearchConceptsLate presentationPreterm birthGestational ageSingle academic medical centerPatient-level risk factorsIndex pregnancy outcomeRisk of presentationMean gestational agePreterm birth preventionRetrospective cohort studySpontaneous preterm birthLate prenatal careYoung maternal ageRisk of recurrenceWeeks of pregnancyLater gestational agesEarly prenatal care initiationPrenatal care initiationAcademic medical centerBirth preventionCohort studyCurrent smokingLate presentersPatient characteristicsPregnancy outcomes