2024
Obstetric Complications and Birth Outcomes After Antenatal Coronavirus Disease 2019 (COVID-19) Vaccination
Vesco K, Denoble A, Lipkind H, Kharbanda E, DeSilva M, Daley M, Getahun D, Zerbo O, Naleway A, Jackson L, Williams J, Boyce T, Fuller C, Weintraub E, Vazquez-Benitez G. Obstetric Complications and Birth Outcomes After Antenatal Coronavirus Disease 2019 (COVID-19) Vaccination. Obstetrics And Gynecology 2024, 143: 794-802. PMID: 38626447, PMCID: PMC11090513, DOI: 10.1097/aog.0000000000005583.Peer-Reviewed Original ResearchConceptsSmall-for-gestational ageMessenger RNA COVID-19 vaccineGestational diabetes mellitusRisk of adverse pregnancy outcomesAdverse pregnancy outcomesPreterm birthGestational hypertensionAdjusted hazard ratiosCOVID-19 vaccine dosesPregnancy outcomesCOVID-19 vaccineAssociated with small-for-gestational ageIncreased risk of adverse pregnancy outcomesVaccine doseRisk of preterm birthMessenger RNARetrospective cohort study of individualsMRNA COVID-19 vaccineWeeks of gestationRetrospective cohort studyHistory of COVID-19Cohort study of individualsVaccine Safety DatalinkSingleton pregnanciesUnexposed pregnanciesUrinary Tract Infection and Progression to Pyelonephritis: Group B Streptococcus versus E. coli
Sachdeva S, Rosett H, Krischak M, Weaver K, Heine R, Denoble A, Dotters-Katz S. Urinary Tract Infection and Progression to Pyelonephritis: Group B Streptococcus versus E. coli. American Journal Of Perinatology Reports 2024, 14: e80-e84. PMID: 38370326, PMCID: PMC10874690, DOI: 10.1055/s-0044-1779031.Peer-Reviewed Original ResearchLower urinary tract infectionsLow birth weightUrinary tract infectionHistory of ACLength of stayPreterm deliveryGestational agePreterm birthTract infectionsPregnant womenRetrospective cohort of pregnant womenGroup B <i>Streptococcus</i> (GBPrimary outcomeHistory of preterm birthMedical records of womenCohort of pregnant womenLow birth weight rateAssociated with severe infectionsMedian gestational ageMedian length of stayGroup B streptococciLower urinary tractRecords of womenPrimary infection typeMedian GA
2023
Maternal and Pregnancy Outcomes Following Heart Transplantation in the United States
Craig A, Campbell A, Snow S, Spates T, Goldstein S, Denoble A, Meng M, Schroder J, Flores K, Agarwal R, Ward C, Federspiel J. Maternal and Pregnancy Outcomes Following Heart Transplantation in the United States. JACC Heart Failure 2023, 11: 1666-1674. PMID: 37804312, PMCID: PMC10841668, DOI: 10.1016/j.jchf.2023.08.018.Peer-Reviewed Original ResearchNontransfusion severe maternal morbiditySevere maternal morbidityHT recipientsHeart transplantationPreterm birthDelivery hospitalizationsGreater oddsPregnancy outcomesRate of SMMNationwide Readmissions DatabaseOutcome of pregnancyHigher readmission ratesProportional hazards regressionHigh morbidity rateMaternal morbidityReadmission ratesHospital readmissionAdjusted analysisComorbid conditionsClinical comorbiditiesHazards regressionMorbidity rateHigh riskHT historyDays postpartum
2020
Beyond Expert Opinion: A Comparison of Antibiotic Regimens for Infectious Urinary Tract Pathology in Pregnancy
Krischak MK, Rosett HA, Sachdeva S, Weaver KE, Heine RP, Denoble AE, Dotters-Katz SK. Beyond Expert Opinion: A Comparison of Antibiotic Regimens for Infectious Urinary Tract Pathology in Pregnancy. American Journal Of Perinatology Reports 2020, 10: e352-e356. PMID: 33094027, PMCID: PMC7571572, DOI: 10.1055/s-0040-1718384.Peer-Reviewed Original ResearchLower urinary tract infectionsFirst-line therapyLow birth weightPreterm birthSMZ-TMPSingle health care systemAdverse obstetric outcomesOdds of progressionReceipt of antibioticsRisk of progressionUrinary tract infectionLength of stayUrinary tract pathologyOdds of outcomesHealth care systemAcute cystitisAsymptomatic bacteriuriaAntibiotic regimensObstetric outcomesOutside pregnancyRetrospective cohortSecondary outcomesTract infectionsPrimary outcomeOptimal antibioticsLower Urinary Pathogens: Do More Pathogenic Bacteria Increase the Risk of Pyelonephritis?
Rosett HA, Krischak MK, Sachdeva S, Weaver KE, Heine RP, Denoble AE, Dotters-Katz SK. Lower Urinary Pathogens: Do More Pathogenic Bacteria Increase the Risk of Pyelonephritis? American Journal Of Perinatology 2020, 39: 473-478. PMID: 32971563, DOI: 10.1055/s-0040-1717093.Peer-Reviewed Original ResearchConceptsLower urinary tract infectionsHistory of preeclampsiaPreterm birthPregnant womenLow birthweightPathogenic infectionsOutside of pregnancyRisk of pyelonephritisOdds of progressionSingle tertiary centerPreterm birth rateRisk of progressionUrinary tract infectionBody mass indexRate of progressionHistory of pyelonephritisAsymptomatic bacteriuriaChronic hypertensionMedian LOSObstetric outcomesUrinary culturePostpartum dataRetrospective cohortSecondary outcomesTract infectionsChorioamnionitis versus intraamniotic infection among preterm deliveries—is postpartum infectious morbidity different?
Denoble AE, Wu J, Mitchell CJ, Hughes BL, Dotters-Katz SK. Chorioamnionitis versus intraamniotic infection among preterm deliveries—is postpartum infectious morbidity different? American Journal Of Obstetrics & Gynecology MFM 2020, 2: 100176. PMID: 33345890, DOI: 10.1016/j.ajogmf.2020.100176.Peer-Reviewed Original ResearchConceptsPostpartum infectious morbidityIntraamniotic infectionClinical chorioamnionitisPostpartum endometritisAntibiotic treatmentMaternal temperatureAmerican CollegeInfectious morbidityPreterm deliveryPotential confoundersGynecologists criteriaAdditional clinical risk factorsAntenatal magnesium sulfateIntrapartum antibiotic treatmentPostpartum endometritis ratePostpartum infectious complicationsClinical risk factorsMultivariate logistic regressionOriginal study populationProportion of womenEndometritis ratesFetal morbidityInfectious complicationsPreterm birthPrimary outcome
2019
Factors Associated with Utilization of 17-Hydroxyprogesterone Caproate for the Prevention of Recurrent Preterm Birth
DeNoble AE, Wynn CE, Weaver KE, Wheeler SM, Swamy GK. Factors Associated with Utilization of 17-Hydroxyprogesterone Caproate for the Prevention of Recurrent Preterm Birth. American Journal Of Perinatology 2019, 37: 264-270. PMID: 30708392, DOI: 10.1055/s-0039-1678532.Peer-Reviewed Original ResearchConceptsSpontaneous preterm birthPrior term birthPrenatal care initiationEligible womenPreterm birthPrimary outcomeTerm birthsWeeks' gestationCare initiationHispanic ethnicityRecurrent spontaneous preterm birthSingleton spontaneous preterm birthPrior spontaneous preterm birthRecurrent preterm birthRetrospective cohort studyAcademic health systemStepwise logistic regressionSPTB rateCohort studyEligible subjectsSingleton pregnanciesClinical predictorsPoor adherenceMaternal ageCare barriersBeyond the Window: Patient Characteristics and Geographic Locations Associated with Late Prenatal Care in Women Eligible for 17-P Preterm Birth Prevention
Wheeler S, DeNoble A, Wynn C, Weaver K, Swamy G, Janko M, Lantos P. Beyond the Window: Patient Characteristics and Geographic Locations Associated with Late Prenatal Care in Women Eligible for 17-P Preterm Birth Prevention. Journal Of Racial And Ethnic Health Disparities 2019, 6: 563-569. PMID: 30632084, DOI: 10.1007/s40615-018-00555-8.Peer-Reviewed Original ResearchConceptsLate presentationPreterm birthGestational ageSingle academic medical centerPatient-level risk factorsIndex pregnancy outcomeRisk of presentationMean gestational agePreterm birth preventionRetrospective cohort studySpontaneous preterm birthLate prenatal careYoung maternal ageRisk of recurrenceWeeks of pregnancyLater gestational agesEarly prenatal care initiationPrenatal care initiationAcademic medical centerBirth preventionCohort studyCurrent smokingLate presentersPatient characteristicsPregnancy outcomes