2024
426 Brain natriuretic peptide testing and severe maternal morbidity in pregnancies affected by heart disease
Denoble A, Federspiel J, Goldstein S, Culhane J, Dysart K. 426 Brain natriuretic peptide testing and severe maternal morbidity in pregnancies affected by heart disease. American Journal Of Obstetrics And Gynecology 2024, 230: s235-s236. DOI: 10.1016/j.ajog.2023.11.452.Peer-Reviewed Original Research
2023
Maternal and Pregnancy Outcomes Following Heart Transplantation in the United States
Craig A, Campbell A, Snow S, Spates T, Goldstein S, Denoble A, Meng M, Schroder J, Flores K, Agarwal R, Ward C, Federspiel J. Maternal and Pregnancy Outcomes Following Heart Transplantation in the United States. JACC Heart Failure 2023, 11: 1666-1674. PMID: 37804312, PMCID: PMC10841668, DOI: 10.1016/j.jchf.2023.08.018.Peer-Reviewed Original ResearchNontransfusion severe maternal morbiditySevere maternal morbidityHT recipientsHeart transplantationPreterm birthDelivery hospitalizationsGreater oddsPregnancy outcomesRate of SMMNationwide Readmissions DatabaseOutcome of pregnancyHigher readmission ratesProportional hazards regressionHigh morbidity rateMaternal morbidityReadmission ratesHospital readmissionAdjusted analysisComorbid conditionsClinical comorbiditiesHazards regressionMorbidity rateHigh riskHT historyDays postpartumAssociations between Anemia and Outcomes of Pregnant Patients with Pyelonephritis
Cunningham H, Knochenhauer H, Federspiel J, Wein L, Denoble A, Heine R, Dotters-Katz S. Associations between Anemia and Outcomes of Pregnant Patients with Pyelonephritis. American Journal Of Perinatology 2023, 41: e2403-e2409. PMID: 37339672, PMCID: PMC10799185, DOI: 10.1055/a-2113-2892.Peer-Reviewed Original ResearchSevere maternal morbidityNationwide Readmissions DatabaseMaternal morbidityPregnant patientsAcute respiratory distress syndromeAdverse maternal outcomesLonger hospital stayAcute renal failureDisease Control criteriaRetrospective cohort studyRespiratory distress syndromeWeighted national estimateComplex survey methodsMaternal comorbiditiesNonanemic patientsHospital stayMaternal outcomesBaseline characteristicsRenal failureCohort studyDistress syndromePrimary outcomeSepsis riskAnemic patientsClinical comorbiditiesAntihypertensives in Pregnancy
Denoble A, Goldstein S, Pettker C. Antihypertensives in Pregnancy. Obstetrics And Gynecology Clinics Of North America 2023, 50: 39-78. PMID: 36822710, DOI: 10.1016/j.ogc.2022.10.008.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsSignificant maternal morbidityTreatment of hypertensionAmniotic fluid volumeHypertensive disordersMaternal morbidityPregnant patientsFetal growthCurrent guidelinesEfficacy dataAvailable safetyPregnancyAntihypertensivesFluid volumeClose supervisionHypertensionMorbidityPatientsPostpartumMortalityAvailable dataDiagnosis
2022
Impact of Pre-Existing Ischemic Heart Disease on Severe Maternal Morbidity and Mortality During Delivery Hospitalizations
Denoble A, Goldstein S, Wein L, Grotegut C, Federspiel J. Impact of Pre-Existing Ischemic Heart Disease on Severe Maternal Morbidity and Mortality During Delivery Hospitalizations. JACC Advances 2022, 1: 100157. PMID: 36684662, PMCID: PMC9851052, DOI: 10.1016/j.jacadv.2022.100157.Peer-Reviewed Original ResearchSevere maternal morbidityIschemic heart diseaseDelivery hospitalizationsComplex survey methodsCardiac diseaseCardiac diagnosisMaternal morbidityHeart diseasePre-existing ischaemic heart diseasePre-existing ischemic heart diseaseNontransfusion severe maternal morbidityWorld Health Organization classificationClass IAdverse pregnancy outcomesNationwide Readmissions DatabaseRelative risk regressionWorld Health Organization class IPregnancy outcomesPrimary outcomeRetrospective studyAdverse outcomesUnadjusted analysesOrganization classificationRisk regressionWorse outcomesComparison of severe maternal morbidity in pregnancy by modified World Health Organization Classification of maternal cardiovascular risk
Denoble AE, Goldstein SA, Wein LE, Grotegut CA, Federspiel JJ. Comparison of severe maternal morbidity in pregnancy by modified World Health Organization Classification of maternal cardiovascular risk. American Heart Journal 2022, 250: 11-22. PMID: 35526569, PMCID: PMC9836743, DOI: 10.1016/j.ahj.2022.04.009.Peer-Reviewed Original ResearchConceptsSevere maternal morbidityWorld Health Organization classificationDelivery hospitalizationsCardiac diagnosisMaternal morbidityOrganization classificationMaternal cardiovascular riskNationwide Readmissions DatabaseRisk of deathSevere cardiac diseaseWeighted national estimateMWHO classificationDelivery admissionCardiovascular riskPregnant patientsSecondary outcomesPrimary outcomeRetrospective studyYear postpartumPregnancy counselingPrimary exposureMonths postpartumNationwide databaseCardiac diseaseElevated riskImpact of chronic ischemic heart disease on severe maternal morbidity during delivery hospitalizations
Denoble A, Goldstein S, Grotegut C, Federspiel J. Impact of chronic ischemic heart disease on severe maternal morbidity during delivery hospitalizations. American Journal Of Obstetrics And Gynecology 2022, 226: s77. DOI: 10.1016/j.ajog.2021.11.146.Peer-Reviewed Original ResearchImpact of mechanical versus bioprosthetic heart valve on severe maternal morbidity during delivery hospitalizations
Denoble A, Federspiel J, Goldstein S, Grotegut C. Impact of mechanical versus bioprosthetic heart valve on severe maternal morbidity during delivery hospitalizations. American Journal Of Obstetrics And Gynecology 2022, 226: s469-s470. DOI: 10.1016/j.ajog.2021.11.778.Peer-Reviewed Original Research
2021
Management of Cerclage in Patients With Preterm Prelabor Rupture of Membranes
Wu J, Denoble AE, Kuller JA, Dotters-Katz SK. Management of Cerclage in Patients With Preterm Prelabor Rupture of Membranes. Obstetrical & Gynecological Survey 2021, 76: 681-691. PMID: 34854925, DOI: 10.1097/ogx.0000000000000957.Peer-Reviewed Original ResearchConceptsMaternal infectious morbidityPreterm prelabor ruptureCerclage removalCervical cerclageInfectious morbidityNeonatal outcomesPrelabor ruptureNeonatal morbidity outcomesRetention of cerclageSetting of PPROMTime of PPROMTime of diagnosisCerclage placementCerclage retentionLatency antibioticsNeonatal complicationsCorticosteroid administrationMaternal morbidityPreterm laborNeonatal sepsisMorbidity outcomesNeonatal mortalityRetrospective natureDefinitive benefitPPROM734 Severe maternal morbidity by modified WHO classification in women with cardiac disease in pregnancy
DeNoble A, Federspiel J, Wein L, Goldstein S, Grotegut C. 734 Severe maternal morbidity by modified WHO classification in women with cardiac disease in pregnancy. American Journal Of Obstetrics And Gynecology 2021, 224: s460-s461. DOI: 10.1016/j.ajog.2020.12.757.Peer-Reviewed Original Research
2019
Spiking in the Second Stage: The Significance of Isolated Maternal Fever During Labor [16A]
Smith M, Daifotis H, Denoble A, Dotters-Katz S. Spiking in the Second Stage: The Significance of Isolated Maternal Fever During Labor [16A]. Obstetrics And Gynecology 2019, 133: 14s-14s. DOI: 10.1097/01.aog.0000559363.72958.65.Peer-Reviewed Original ResearchAdverse maternal outcomesMaternal outcomesAntibiotic receiptPostpartum infectionMaternal feverBlood transfusionAdverse postpartum outcomesIsolated maternal feverPostpartum maternal outcomesPostpartum venous thromboembolismRetrospective cohort studyTwin vaginal deliverySigns of infectionTiming of deliveryAntepartum complicationsDelivery BMIIntraamniotic infectionMaternal morbidityVenous thromboembolismCohort studyHospital readmissionPrimary outcomeVaginal deliveryPostpartum outcomesNineteen women
2018
Antibiotics for the Prevention and Treatment of Postsurgical Obstetric Infections
DeNoble AE, Kuller JA, Heine RP, Dotters-Katz S. Antibiotics for the Prevention and Treatment of Postsurgical Obstetric Infections. Obstetrical & Gynecological Survey 2018, 73: 475-485. PMID: 30169886, DOI: 10.1097/ogx.0000000000000590.Peer-Reviewed Original ResearchConceptsPostsurgical infectionsObstetric infectionsProphylactic antibioticsCesarean deliverySystematic reviewAvailable evidenceLimited retrospective studyUnlabored cesarean deliveryCornerstone of preventionEvidence-based guidelinesCommon bacterial isolatesEffective antibiotic regimenSecond-generation cephalosporinsAntibiotic resistanceSearch of PubMedAntibiotic selectionFirst-generation cephalosporinsRelevant original research articlesGlobal health threatAdjunctive azithromycinAntibiotic prophylaxisInfectious complicationsMaternal morbidityAntibiotic regimenOperative intervention