1965-LB: Metabolomic and Transcriptomic Signatures of Gestational Diabetes Mellitus (GDM) Suggest Nutritional and Inflammatory Pathways in Intergenerational Transfer of Risk
THAKER V, FIRESTEIN M, MASSON C, LIU Z, REDDY U, GALLAGHER D, LEDUC C. 1965-LB: Metabolomic and Transcriptomic Signatures of Gestational Diabetes Mellitus (GDM) Suggest Nutritional and Inflammatory Pathways in Intergenerational Transfer of Risk. Diabetes 2024, 73 DOI: 10.2337/db24-1965-lb.Peer-Reviewed Original ResearchGestational diabetes mellitusMetabolic riskC-peptideCord blood C-peptideCord blood metabolitesBlood C-peptideMother-baby dyadsCord plasmaCord bloodSteroid hormone signalingMaternal milieuTransport abnormalitiesPlacental tissuePregnancy ageDiabetes mellitusOffspring birthweightPlacental transcriptomePlasma fructosamineInflammatory pathwaysInflammatory processPlacenta tissueINSR expressionCordMetabolite profilesObesity