Turnover of Rat Brain Perivascular Cells
Bechmann I, Kwidzinski E, Kovac A, Simbürger E, Horvath T, Gimsa U, Dirnagl U, Priller J, Nitsch R. Turnover of Rat Brain Perivascular Cells. Experimental Neurology 2001, 168: 242-249. PMID: 11259112, DOI: 10.1006/exnr.2000.7618.Peer-Reviewed Original ResearchConceptsBrain perivascular spacesBone marrow transplantationPerivascular spacesPerivascular cellsMarrow transplantationAdult ratsBlood borne macrophagesBrain perivascular cellsHealthy adult ratsEx vivo isolationMonocyte/macrophage lineageHigh phagocytic capacityNormal adult ratsMHC mismatchIntraventricular injectionBrain parenchymaIntracerebral injectionAntigen presentationImmune surveillanceDonor macrophagesPhagocytic capacityMacrophage lineageMacrophagesVivo isolationSame animals