2021
Poor retention and care-related sex disparities among youth living with HIV in rural Mozambique
Ahonkhai AA, Aliyu MH, Audet CM, Bravo M, Simmons M, Claquin G, Memiah P, Fernando AN, Carlucci JG, Shepherd BE, Van Rompaey S, Yu Z, Gong W, Vermund SH, Wester CW. Poor retention and care-related sex disparities among youth living with HIV in rural Mozambique. PLOS ONE 2021, 16: e0250921. PMID: 34019582, PMCID: PMC8139489, DOI: 10.1371/journal.pone.0250921.Peer-Reviewed Original ResearchConceptsHigher oddsCombination antiretroviral therapy (cART) initiationCox proportional hazards modelCare continuum outcomesComprehensive HIV programsPost-ART initiationYoung adults 15Antiretroviral therapy initiationRetrospective cohort studySex-related disparitiesMultivariable logistic regressionOne-year followProportional hazards modelYears of agePL femalesSex-related differencesART initiationAYA cohortTherapy initiationCohort studyContinuum outcomesHIV outcomesClinical visitsAdults 15HIV programs
2019
Attrition of HIV-positive children from HIV services in low and middle-income countries.
Carlucci JG, Liu Y, Clouse K, Vermund SH. Attrition of HIV-positive children from HIV services in low and middle-income countries. AIDS 2019, 33: 2375-2386. PMID: 31764102, PMCID: PMC6905128, DOI: 10.1097/qad.0000000000002366.Peer-Reviewed Original ResearchMeSH KeywordsAnti-HIV AgentsChildDeveloping CountriesHIV InfectionsHumansLost to Follow-UpRetention in CareVulnerable PopulationsConceptsHIV-positive childrenHIV servicesAntiretroviral therapyMiddle-income countriesEarly ART initiationPatient support servicesOptimal health outcomesMeta-regression analysisART initiationLTFU definitionStudy eligibilityMagnitude of attritionEligibility criteriaHealth outcomesSystematic reviewRandom-effects meta-analytic methodsOverall attritionMeta-analytic methodsMultidatabase searchData extractionVulnerable populationsImplementation researchMonthsMost attritionLTFU
2017
Mobility and Clinic Switching Among Postpartum Women Considered Lost to HIV Care in South Africa
Clouse K, Vermund SH, Maskew M, Lurie MN, MacLeod W, Malete G, Carmona S, Sherman G, Fox MP. Mobility and Clinic Switching Among Postpartum Women Considered Lost to HIV Care in South Africa. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2017, 74: 383-389. PMID: 28225717, PMCID: PMC5324708, DOI: 10.1097/qai.0000000000001284.Peer-Reviewed Original ResearchConceptsHIV careNational Health Laboratory Service databaseLow CD4 cell countsNational Antiretroviral Therapy ProgramCD4 cell countObservational cohort studyAntiretroviral therapy programsAntiretroviral therapyCohort studyPostpartum womenPublic clinicsService databaseCell countTherapy programCareWomenLTFUClinicOne-thirdDaysPatientsPregnancyTherapy
2016
Risk Factors for Loss to Follow-Up among People Who Inject Drugs in a Risk Reduction Program at Karachi, Pakistan. A Case-Cohort Study
Samo RN, Agha A, Shah SA, Altaf A, Memon A, Blevins M, Qian HZ, Vermund SH. Risk Factors for Loss to Follow-Up among People Who Inject Drugs in a Risk Reduction Program at Karachi, Pakistan. A Case-Cohort Study. PLOS ONE 2016, 11: e0147912. PMID: 26840414, PMCID: PMC4739707, DOI: 10.1371/journal.pone.0147912.Peer-Reviewed Original ResearchConceptsCase-cohort studyMale PWIDHarm reduction programsRisk reduction programsRisk factorsReduction programsNeedle/syringe exchangeProspective cohort studyMultivariable logistic regressionResource-limited settingsHistory of incarcerationCohort studyMedian ageIncidence rateSyringe exchangePWIDMale peopleYounger ageLogistic regressionYoung menMonthsKarachiMenActive outreachProgrammatic challenges
2015
Practical Management of HIV-Associated Anemia in Resource-Limited Settings: Prospective Observational Evaluation of a New Mozambican Guideline
Brentlinger PE, Silva WP, Vermund SH, Valverde E, Buene M, Moon TD. Practical Management of HIV-Associated Anemia in Resource-Limited Settings: Prospective Observational Evaluation of a New Mozambican Guideline. AIDS Research And Human Retroviruses 2015, 32: 12-25. PMID: 26178574, PMCID: PMC4692124, DOI: 10.1089/aid.2015.0030.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnemiaAnthelminticsAnti-HIV AgentsAntimalarialsAntitubercular AgentsCD4 Lymphocyte CountCoinfectionDeveloping CountriesDisease ManagementFemaleHelminthiasisHemoglobinsHIV InfectionsHumansLost to Follow-UpMalaria, FalciparumMaleMozambiquePractice Guidelines as TopicProspective StudiesRural PopulationTuberculosis, PulmonaryConceptsHIV-associated anemiaAdverse drug reactionsDrug reactionsHemoglobin responseGuideline revisionsIron deficiencyLower body mass indexCo-trimoxazole prophylaxisDiscontinuation of zidovudineLaboratory-confirmed malariaProspective observational evaluationRural Zambézia ProvinceT-cell countsT-lymphocyte countsSmear-positive tuberculosisBody mass indexResource limited settingsResource-limited settingsLogistic regression modelsAnaemic HIVStudy cliniciansAntiretroviral therapyEsophageal candidiasisPresumptive treatmentAnemia management
2014
Two-Year Death and Loss to Follow-Up Outcomes by Source of Referral to HIV Care for HIV-Infected Patients Initiating Antiretroviral Therapy in Rural Mozambique
Blevins M, José E, Bilhete FR, Vaz LM, Shepherd BE, Audet CM, Vermund SH, Moon TD. Two-Year Death and Loss to Follow-Up Outcomes by Source of Referral to HIV Care for HIV-Infected Patients Initiating Antiretroviral Therapy in Rural Mozambique. AIDS Research And Human Retroviruses 2014, 31: 198-207. PMID: 25381732, PMCID: PMC4532902, DOI: 10.1089/aid.2014.0007.Peer-Reviewed Original ResearchConceptsSource of referralCombination antiretroviral therapyRural Zambézia ProvinceReferral sitesAntiretroviral therapyAntenatal careGeneral outpatient clinicCumulative incidence estimatesAdditional unmeasured factorsCART initiationHIV careHazard ratioPatient characteristicsHIV testingMedian ageVoluntary counselingCox regressionOutpatient clinicKaplan-MeierPatient populationMedication pickupPatient outcomesInpatient careLTFUIncidence estimatesPoor Clinical Outcomes for HIV Infected Children on Antiretroviral Therapy in Rural Mozambique: Need for Program Quality Improvement and Community Engagement
Vermund SH, Blevins M, Moon TD, José E, Moiane L, Tique JA, Sidat M, Ciampa PJ, Shepherd BE, Vaz LM. Poor Clinical Outcomes for HIV Infected Children on Antiretroviral Therapy in Rural Mozambique: Need for Program Quality Improvement and Community Engagement. PLOS ONE 2014, 9: e110116. PMID: 25330113, PMCID: PMC4203761, DOI: 10.1371/journal.pone.0110116.Peer-Reviewed Original ResearchConceptsCombination antiretroviral therapyAntiretroviral therapyInfant diagnosisClinical outcomesEarly infant diagnosisPoor clinical outcomeYears of ageResource-limited settingsUnknown clinical outcomesCohort mortality ratesQuality improvement effortsART initiationCART initiationRural MozambiqueHIV servicesAdults 15HIV prevalenceKaplan-MeierHigher hemoglobinMedication pickupClinical dataOutcome treatmentNational guidelinesCase findingZambézia Province