2018
Impact of HIV on human papilloma virus-mediated cervical disease progression
Vermund SH, Kelley KF. Impact of HIV on human papilloma virus-mediated cervical disease progression. AIDS 2018, 32: 1715-1717. PMID: 30001245, PMCID: PMC7024578, DOI: 10.1097/qad.0000000000001841.Peer-Reviewed Original Research
2017
Human Immunodeficiency Virus Status Differentially Associated With Genital and Anal Human Papillomavirus Infection Among Chinese Men Who Have Sex With Men
Qian HZ, Hu Y, Carlucci JG, Yin L, Li X, Giuliano AR, Li D, Gao L, Shao Y, Vermund SH. Human Immunodeficiency Virus Status Differentially Associated With Genital and Anal Human Papillomavirus Infection Among Chinese Men Who Have Sex With Men. Sexually Transmitted Diseases 2017, 44: 656-662. PMID: 28876311, PMCID: PMC5719885, DOI: 10.1097/olq.0000000000000672.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virus statusAnal HPVHuman papillomavirus infectionOncogenic HPV typesGenital HPVHIV seropositivityPapillomavirus infectionHPV typesVirus statusAnal siteAnatomic sitesAnal sexAnal human papillomavirus (HPV) infectionInsertive anal sexReceptive anal sexCross-sectional studyInconsistent condom useUninfected MSMHPV genotypingMiddle-income countriesHIV serostatusHuman papillomavirusChinese MSMHPVChinese men
2016
Rates and determinants of incidence and clearance of cervical HPV genotypes among HIV-seropositive women in Pune, India
Mane A, Sahasrabuddhe VV, Nirmalkar A, Risbud AR, Sahay S, Bhosale RA, Vermund SH, Mehendale SM. Rates and determinants of incidence and clearance of cervical HPV genotypes among HIV-seropositive women in Pune, India. Journal Of Clinical Virology 2016, 88: 26-32. PMID: 28152432, PMCID: PMC5441893, DOI: 10.1016/j.jcv.2016.10.013.Peer-Reviewed Original ResearchMeSH KeywordsAdultCervix UteriFemaleGenotypeHIV InfectionsHumansIncidenceIndiaPapillomaviridaePapillomavirus InfectionsProspective StudiesConceptsHIV-seropositive womenCervical HPV genotypesHPV genotypesClearance rateHPV infectionAge-related hormonal changesRoche Linear Array HPVAlpha-7 speciesAntiretroviral therapy statusCarcinogenic HPV genotypesCervical HPV infectionGenotype-specific prevalenceLinear Array HPVAge of participantsCD4 countHPV incidenceImmunologic factorsDeterminants of incidenceHPV typesTherapy statusProspective studyCervical samplesIncidence rateHormonal changesEtiologic studiesSpousal migration and human papillomavirus infection among women in rural western Nepal
Johnson DC, Lhaki P, Bhatta MP, Kempf MC, Smith JS, Bhattarai P, Aryal S, Chamot E, Regmi K, Vermund SH, Shrestha S. Spousal migration and human papillomavirus infection among women in rural western Nepal. International Health 2016, 8: 261-268. PMID: 27048288, PMCID: PMC4967846, DOI: 10.1093/inthealth/ihw015.Peer-Reviewed Original ResearchConceptsHR-HPV infectionCytology statusHR-HPVHuman papillomavirus (HPV) infection statusAbnormal cervical cytologyHuman papillomavirus infectionAtypical glandular cellsAssociation of migrationPapillomavirus infectionCervical cytologyUndetermined significanceCare centerHigh prevalenceOlder womenBethesda SystemHealth campsStudy participantsOlder ageInfection statusYoung womenGlandular cellsInfectionMigration statusWomenPrevalenceHigher Prevalence of Human Papillomavirus-Related Cervical Precancerous Abnormalities in HIV-Infected Compared to HIV-Uninfected Women
Choudhury SA, Choudhury NA, Humphrey AD, Berthaud V, Ladson G, Tucker VA, Vermund SH. Higher Prevalence of Human Papillomavirus-Related Cervical Precancerous Abnormalities in HIV-Infected Compared to HIV-Uninfected Women. Journal Of The National Medical Association 2016, 108: 19-23. PMID: 26928484, PMCID: PMC10767705, DOI: 10.1016/j.jnma.2015.12.003.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentComorbidityFemaleHIV InfectionsHumansPapillomaviridaePapillomavirus InfectionsPrevalenceTennesseeUterine Cervical NeoplasmsConceptsHigh-risk human papillomavirusNon-Hispanic African American womenNon-Hispanic white womenAfrican American womenPrecancerous lesionsHPV vaccinationHuman papillomavirusMedical recordsHispanic womenPrevalence of HPVPersistent high-risk human papillomavirusWhite womenHIV uninfected groupHIV uninfected womenRoutine HPV vaccinationHPV vaccination ratesRisk human papillomavirusCervical precancerous lesionsAmerican womenHIV-InfectedPrecancerous abnormalitiesUninfected womenHPV vaccineVaccine recipientsCervical abnormalities
2015
The Effect of Cryotherapy on Human Papillomavirus Clearance Among HIV-Positive Women in Lusaka, Zambia
Katundu K, Bateman AC, Pfaendler KS, Mwanahamuntu MH, Kapambwe S, Vermund SH, Sahasrabuddhe VV, Msadabwe SC, Stringer JS, Parham GP, Chibwesha CJ. The Effect of Cryotherapy on Human Papillomavirus Clearance Among HIV-Positive Women in Lusaka, Zambia. Journal Of Lower Genital Tract Disease 2015, 19: 301-306. PMID: 26125097, PMCID: PMC4583804, DOI: 10.1097/lgt.0000000000000131.Peer-Reviewed Original ResearchConceptsHIV-positive womenWeeks of treatmentHrHPV infectionHrHPV typesHigh-risk HPV cervical infectionHigh HIV burden settingsHIV burden settingsHPV cervical infectionHuman papillomavirus clearancePrevalence of hrHPVCommon HPV typesHuman papillomavirus infectionRoche Linear ArrayEffects of cryotherapyHPV vaccinationMedian CD4Antiretroviral therapyCervical infectionCohort studyPapillomavirus infectionBurden settingsCervical diseaseHPV typesMedian ageCervical screening
2014
Assessment of High-Risk Human Papillomavirus Infections Using Clinician- and Self-Collected Cervical Sampling Methods in Rural Women from Far Western Nepal
Johnson DC, Bhatta MP, Smith JS, Kempf MC, Broker TR, Vermund SH, Chamot E, Aryal S, Lhaki P, Shrestha S. Assessment of High-Risk Human Papillomavirus Infections Using Clinician- and Self-Collected Cervical Sampling Methods in Rural Women from Far Western Nepal. PLOS ONE 2014, 9: e101255. PMID: 24978811, PMCID: PMC4076302, DOI: 10.1371/journal.pone.0101255.Peer-Reviewed Original ResearchConceptsHigh-grade squamous intraepithelial lesionsRural Nepali womenHR-HPVSquamous cell carcinomaHuman papillomavirusHigh-risk human papillomavirus infectionHigh cervical cancer ratesOverall HR-HPV prevalenceSelf-collected cervical samplesHigh-risk HPV typesGrade squamous intraepithelial lesionNepali womenClinician-collected samplesHR-HPV mRNAHR-HPV prevalenceSelf-collected testsCervical cancer ratesHuman papillomavirus infectionSelf-collected samplesSquamous intraepithelial lesionsAuxiliary nurse midwivesPre-cancer lesionsCervico-vaginal specimensSelf-collection methodType-specific distribution
2013
Anal Human Papillomavirus Infection Among HIV-Infected and Uninfected Men Who Have Sex With Men in Beijing, China
Hu Y, Qian HZ, Sun J, Gao L, Yin L, Li X, Xiao D, Li D, Sun X, Ruan Y, Milam DF, Pan SW, Shao Y, Vermund SH. Anal Human Papillomavirus Infection Among HIV-Infected and Uninfected Men Who Have Sex With Men in Beijing, China. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2013, 64: 103-114. PMID: 23732908, PMCID: PMC3780393, DOI: 10.1097/qai.0b013e31829b6298.Peer-Reviewed Original ResearchConceptsHuman papillomavirusHPV infectionUninfected menAnal intercourseAnal human papillomavirus (HPV) infectionUnprotected receptive anal intercourseAnal human papillomavirusHPV anal infectionOncogenic HPV prevalenceHuman papillomavirus infectionMultivariable logistic analysisReceptive anal intercourseInterviewer-administrated questionnaireReceptive anal sexInsertive anal intercourseHPV prevalenceHPV vaccinationUninfected MSMUninfected participantsAnal infectionPapillomavirus infectionSyphilis serologyAnal specimensHIV prevalenceHealth workers
2012
HPV Genotype Distribution in Cervical Intraepithelial Neoplasia among HIV-Infected Women in Pune, India
Mane A, Nirmalkar A, Risbud AR, Vermund SH, Mehendale SM, Sahasrabuddhe VV. HPV Genotype Distribution in Cervical Intraepithelial Neoplasia among HIV-Infected Women in Pune, India. PLOS ONE 2012, 7: e38731. PMID: 22723879, PMCID: PMC3378535, DOI: 10.1371/journal.pone.0038731.Peer-Reviewed Original ResearchConceptsCarcinogenic HPV genotypesHPV genotypesLow CD4HPV infectionCIN3 lesionsCommon HPV genotypesHPV genotype distributionMultiple HPV genotypesCombination antiretroviral therapyCervical intraepithelial neoplasiaCarcinogenic HPV infectionHalf of womenQuarter of womenHPV type detectionLifetime sexual partnersCarcinogenic HPVHPV16 detectionAntiretroviral therapyHPV genotypingComposite endpointOrder of prevalenceIntraepithelial neoplasiaCervical cancerHPV 16Observational studyCervical Cancer Prevention in Low- and Middle-Income Countries: Feasible, Affordable, Essential
Sahasrabuddhe VV, Parham GP, Mwanahamuntu MH, Vermund SH. Cervical Cancer Prevention in Low- and Middle-Income Countries: Feasible, Affordable, Essential. Cancer Prevention Research 2012, 5: 11-17. PMID: 22158053, PMCID: PMC3586242, DOI: 10.1158/1940-6207.capr-11-0540.Peer-Reviewed Original ResearchConceptsCervical cancer preventionHuman immunodeficiency virusCervical cancerMiddle-income countriesCancer preventionPrevention servicesCervical cancer prevention servicesCancer prevention servicesCervical cancer screeningGynecologic issuesImmunodeficiency virusHuman papillomavirusCancer screeningEarly treatmentPelvic examHigh-income countriesWorldwide burdenCare deliveryNew casesScreening testHPVCancerLMICsEffective alternativePrevention
2007
Prevalence and distribution of HPV genotypes among HIV-infected women in Zambia
Sahasrabuddhe VV, Mwanahamuntu MH, Vermund SH, Huh WK, Lyon MD, Stringer JS, Parham GP. Prevalence and distribution of HPV genotypes among HIV-infected women in Zambia. British Journal Of Cancer 2007, 96: 1480-1483. PMID: 17437020, PMCID: PMC2360194, DOI: 10.1038/sj.bjc.6603737.Peer-Reviewed Original ResearchMeSH KeywordsCD4 Lymphocyte CountConfidence IntervalsFemaleHIV InfectionsHumansOdds RatioPapillomaviridaePapillomavirus InfectionsZambiaConceptsSquamous cell carcinomaHuman papillomavirusHPV 16High-grade squamous intraepithelial lesionsDistribution of HPVHigh-risk HPV typesCervical cytological abnormalitiesTertiary care centerSquamous intraepithelial lesionsNon-pregnant womenHigh-grade lesionsHigh-risk typesSensitivity of cytologyLiquid-based cytologyHPV-52HPV typesIntraepithelial lesionsProtective immunityCell carcinomaCare centerCytological abnormalitiesHPV assessmentCell countCytologyWomen
2001
Viral latency--the papillomavirus model.
Broker TR, Jin G, Croom-Rivers A, Bragg SM, Richardson M, Chow LT, Vermund SH, Alvarez RD, Pappas PG, Squires KE, Hoesley CJ. Viral latency--the papillomavirus model. 2001, 106: 443-51; discussion 452-3, 465-75. PMID: 11761260.Peer-Reviewed Original ResearchMeSH KeywordsCohort StudiesFemaleHIV InfectionsHumansKidney TransplantationModels, BiologicalPapillomaviridaePapillomavirus InfectionsVaginal SmearsVirus LatencyConceptsHPV typesHPV DNAAIDS cohortEnd-stage renal failureCervico-vaginal lavageKidney transplantation candidatesConsequence of immunosuppressionHuman papillomavirus infectionLower genital tractDifferent HPV typesLatent viral infectionFunctional immune systemHIV/AIDSSub-clinical stateHPV prevalenceHIV cohortHPV infectionKidney transplantationNested polymerase chain reaction amplificationPapillomavirus infectionRenal failureTransplantation candidatesHPV 6Immune depressionImmunosuppressive conditions
2000
Cytokine Profile in Genital Tract Secretions from Female Adolescents: Impact of Human Immunodeficiency Virus, Human Papillomavirus, and Other Sexually Transmitted Pathogens
Crowley-Nowick P, Ellenberg J, Vermund S, Douglas S, Holland C, Moscicki A. Cytokine Profile in Genital Tract Secretions from Female Adolescents: Impact of Human Immunodeficiency Virus, Human Papillomavirus, and Other Sexually Transmitted Pathogens. The Journal Of Infectious Diseases 2000, 181: 939-945. PMID: 10720516, DOI: 10.1086/315311.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentCervix MucusCytokinesEnzyme-Linked Immunosorbent AssayFemaleGenital Diseases, FemaleHIV InfectionsHumansInterleukin-10Interleukin-12Interleukin-2Multivariate AnalysisPapillomaviridaePapillomavirus InfectionsRegression AnalysisSexually Transmitted DiseasesTumor Virus InfectionsConceptsIL-12 concentrationsHuman immunodeficiency virusIL-10Human papillomavirusIL-12Immunodeficiency virusHigher IL-10 concentrationsHIV-positive patientsIL-10 concentrationsGenital tract infectionGenital tract secretionsIL-2 concentrationsQuantitative enzyme-linked immunosorbent assayFemale adolescentsEnzyme-linked immunosorbent assayCytokine profileNegative patientsTract infectionsCervical secretionsConcomitant infectionImmunoregulatory cytokinesTract secretionsGenital tractHIVImmunosorbent assayPrevalence of and Risks for Cervical Human Papillomavirus Infection and Squamous Intraepithelial Lesions in Adolescent Girls: Impact of Infection With Human Immunodeficiency Virus
Moscicki AB, Ellenberg JH, Vermund SH, Holland CA, Darragh T, Crowley-Nowick PA, Levin L, Wilson CM. Prevalence of and Risks for Cervical Human Papillomavirus Infection and Squamous Intraepithelial Lesions in Adolescent Girls: Impact of Infection With Human Immunodeficiency Virus. JAMA Pediatrics 2000, 154: 127-134. PMID: 10665598, DOI: 10.1001/archpedi.154.2.127.Peer-Reviewed Original ResearchConceptsSquamous intraepithelial lesionsHPV infectionHuman papillomavirus infectionIntraepithelial lesionsPapillomavirus infectionHIV infectionHIV statusCervical human papillomavirus infectionLow-risk HPV typesCourse of HIVNormal cytologic findingsCD4 cell countCervical HPV infectionT-cell countsT-cell immunosuppressionHuman immunodeficiency virusHigh-risk typesAdolescent girlsSexual risk behaviorsImpact of infectionCD4 immunosuppressionBaseline visitHPV typesRisky sexual behaviorViral load
1996
Pregnancy and cervical infection with human papillomaviruses
Morrison E, Gammon MD, Goldberg GL, Vermund SH, Burk RD. Pregnancy and cervical infection with human papillomaviruses. International Journal Of Gynecology & Obstetrics 1996, 54: 125-130. PMID: 9236309, DOI: 10.1016/0020-7292(96)02694-x.Peer-Reviewed Original ResearchConceptsPrevalence odds ratiosHPV risk factorsRisk factorsHPV infectionCurrent pregnancyCervical HPV infectionPrevalence of HPVHuman papillomavirus infectionAssociation of pregnancyStatistical significanceLarge municipal hospitalSelf-administered questionnaireRace/ethnicityCervicovaginal lavageCervical infectionPapillomavirus infectionHPV DNAGestational ageGynecological examinationOutpatient clinicHuman papillomavirusSignificant confoundersOdds ratioLavage samplesMunicipal HospitalDeclining Prevalence of Cervicovaginal Human Papillomavirus Infection With Age Is Independent of Other Risk Factors
BURK R, KELLY P, FELDMAN J, BROMBERG J, VERMUND S, DEHOVITZ J, LANDESMAN S. Declining Prevalence of Cervicovaginal Human Papillomavirus Infection With Age Is Independent of Other Risk Factors. Sexually Transmitted Diseases 1996, 23: 333-341. PMID: 8836027, DOI: 10.1097/00007435-199607000-00013.Peer-Reviewed Original ResearchConceptsPrevalence of HPVHuman papillomavirus infectionHPV infectionPapillomavirus infectionRisk factorsCervicovaginal human papillomavirus infectionGenital HPV infectionCervical HPV infectionWomen 45 yearsFemale genital tractLogistic regression analysisYears of ageSexual behaviorInner-city womenAge-dependent declineHPV immunityHPV prevalenceCervical diseaseCervicovaginal cellsGenital tractLow prevalenceOlder womenSex partnersYounger ageBiologic effects
1995
Prevalence of Human Papillomavirus Among STD Clinic Attenders in Jamaica
FIGUEROA J, WARD E, LUTHI T, VERMUND S, BRATHWAITE A, BURK R. Prevalence of Human Papillomavirus Among STD Clinic Attenders in Jamaica. Sexually Transmitted Diseases 1995, 22: 114-118. PMID: 7624812, DOI: 10.1097/00007435-199503000-00007.Peer-Reviewed Original ResearchConceptsHuman papillomavirus infectionHuman papillomavirusPapillomavirus infectionSTD clinicOlder womenHigh HPV prevalenceHuman papillomavirus (HPV) prevalencePrevalence of HPVSTD clinic attendersIncidence of cancerMajor etiologic agentHuman papillomavirus (HPV) genomeLow-stringency Southern blot hybridizationCross-sectional surveyHPV prevalenceEffect of ageClinic attendersCervical cancerWomen 25Risk factorsWomen 20Effective vaccineLow prevalenceWomen 15Etiologic agent
1994
Risk Factors For Squamous Intraepithelial Lesions On Pap Smear In Women At Risk For Human Immunodeficiency Virus Infection
Klein R, Ho G, Vermund S, Fleming I, Burk R. Risk Factors For Squamous Intraepithelial Lesions On Pap Smear In Women At Risk For Human Immunodeficiency Virus Infection. The Journal Of Infectious Diseases 1994, 170: 1404-1409. PMID: 7995978, DOI: 10.1093/infdis/170.6.1404.Peer-Reviewed Original ResearchMeSH KeywordsAdultCarcinoma, Squamous CellCD4 Lymphocyte CountDNA, ViralFemaleHIV AntibodiesHIV InfectionsHumansImmunocompromised HostMiddle AgedMultivariate AnalysisNew YorkOdds RatioPapanicolaou TestPapillomaviridaePapillomavirus InfectionsPrevalenceRisk FactorsTumor Virus InfectionsUterine Cervical DysplasiaUterine Cervical NeoplasmsVaginal SmearsConceptsSquamous intraepithelial lesionsHuman immunodeficiency virus (HIV) infectionImmunodeficiency virus infectionRisk factorsHPV infectionHIV infectionIntraepithelial lesionsPap smearVirus infectionHigh-risk HPV typesGenital HPV infectionHIV antibody testingIndependent risk factorSevere HIVSevere immunosuppressionHPV typesAntibody testingGenital HPVUnivariate analysisMultivariate analysisInfectionGenome detectionImmunosuppressionRiskLesions