2017
Mortality in Children with Human Immunodeficiency Virus Initiating Treatment: A Six-Cohort Study in Latin America
Luque MT, Jenkins CA, Shepherd BE, Padgett D, Rouzier V, Succi RCM, Machado DM, McGowan CC, Vermund SH, Pinto JA. Mortality in Children with Human Immunodeficiency Virus Initiating Treatment: A Six-Cohort Study in Latin America. The Journal Of Pediatrics 2017, 182: 245-252.e1. PMID: 28081884, PMCID: PMC5328796, DOI: 10.1016/j.jpeds.2016.12.034.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveCause of DeathChildChild, PreschoolCohort StudiesConfidence IntervalsDatabases, FactualDose-Response Relationship, DrugDrug Administration ScheduleFemaleHIV InfectionsHumansIncidenceLatin AmericaMaleProportional Hazards ModelsRetrospective StudiesRisk AssessmentSeverity of Illness IndexSurvival AnalysisConceptsCombination antiretroviral therapyYears of ageCART initiationGreater riskCox proportional hazards modelAntiretroviral therapy-naïveMedian CD4 countRetrospective cohort studyProportional hazards modelCumulative mortality incidenceSouth America networkProbability of deathInitiating treatmentMedian CD4Antiretroviral therapyCause mortalityCD4 countTherapy-naïveCohort studyCumulative incidenceHIV epidemiologyPediatric careMortality incidenceHazards modelRegimens
2015
Enrolment trends in a comprehensive HIV programme in rural north-central Nigeria: improved care indices, but declining quality of clinical data over time
Aliyu MH, Blevins M, Arinze F, Megazzini KM, Bussell S, Dunlap J, Odoh C, Gebi UI, Muhammad MY, Shepherd BE, Audet CM, Vermund SH, Wester CW. Enrolment trends in a comprehensive HIV programme in rural north-central Nigeria: improved care indices, but declining quality of clinical data over time. Pathogens And Global Health 2015, 109: 75-83. PMID: 25822098, PMCID: PMC4571821, DOI: 10.1179/2047773215y.0000000007.Peer-Reviewed Original ResearchConceptsComprehensive HIV programsHIV programsComprehensive HIV/AIDS servicesCell countAdvanced clinical diseaseClinical stage INorth Central NigeriaHIV/AIDS servicesRural North-Central NigeriaQuality improvement effortsMedian CD4Clinical stagingMedian ageHIV servicesCare indexClinical dataClinical diseaseStage IAIDS servicesPatientsWindow periodHemoglobin dataClinical servicesEnrollment yearCells/
2014
Two-Year Death and Loss to Follow-Up Outcomes by Source of Referral to HIV Care for HIV-Infected Patients Initiating Antiretroviral Therapy in Rural Mozambique
Blevins M, José E, Bilhete FR, Vaz LM, Shepherd BE, Audet CM, Vermund SH, Moon TD. Two-Year Death and Loss to Follow-Up Outcomes by Source of Referral to HIV Care for HIV-Infected Patients Initiating Antiretroviral Therapy in Rural Mozambique. AIDS Research And Human Retroviruses 2014, 31: 198-207. PMID: 25381732, PMCID: PMC4532902, DOI: 10.1089/aid.2014.0007.Peer-Reviewed Original ResearchConceptsSource of referralCombination antiretroviral therapyRural Zambézia ProvinceReferral sitesAntiretroviral therapyAntenatal careGeneral outpatient clinicCumulative incidence estimatesAdditional unmeasured factorsCART initiationHIV careHazard ratioPatient characteristicsHIV testingMedian ageVoluntary counselingCox regressionOutpatient clinicKaplan-MeierPatient populationMedication pickupPatient outcomesInpatient careLTFUIncidence estimatesRisk Factors for Delayed Initiation of Combination Antiretroviral Therapy in Rural North Central Nigeria
Aliyu MH, Blevins M, Parrish DD, Megazzini KM, Gebi UI, Muhammad MY, Ahmed ML, Hassan A, Shepherd BE, Vermund SH, Wester CW. Risk Factors for Delayed Initiation of Combination Antiretroviral Therapy in Rural North Central Nigeria. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2014, 65: e41-e49. PMID: 23727981, PMCID: PMC3818360, DOI: 10.1097/qai.0b013e31829ceaec.Peer-Reviewed Original ResearchConceptsCombination antiretroviral therapyAntiretroviral therapyDate of enrollmentART initiationCD4 countFunctional statusInitiation of ARTMedian CD4 countHigher CD4 countsLower functional statusMonths of enrollmentBody mass indexART eligibility criteriaAdults/adolescentsRural North-Central NigeriaHIV/AIDSQuality improvement effortsEligible HIVEligible patientsPatient characteristicsART uptakeMass indexRisk factorsTimely initiationDelayed initiation
2013
Impact of HIV drug resistance on virologic and immunologic failure and mortality in a cohort of patients on antiretroviral therapy in China
Liao L, Xing H, Su B, Wang Z, Ruan Y, Wang X, Liu Z, Lu Y, Yang S, Zhao Q, Vermund SH, Chen RY, Shao Y. Impact of HIV drug resistance on virologic and immunologic failure and mortality in a cohort of patients on antiretroviral therapy in China. AIDS 2013, 27: 1815-1824. PMID: 23803794, PMCID: PMC3694318, DOI: 10.1097/qad.0b013e3283611931.Peer-Reviewed Original ResearchConceptsCombination antiretroviral therapyHIV drug resistanceImmunologic failureHigh mortalityVirologic failureAntiretroviral therapyEmergence of HIVDRBaseline CD4 cell countDrug resistanceCD4 cell countCohort of patientsSecond-line drugsEnd of studyProportional hazards modelRural Chinese countiesHIVDR mutationsMedian timePatient adherenceKaplan-MeierChinese patientsRisk factorsHazards modelPatientsCell countMortality
1998
Serum Retinol and HIV-1 RNA Viral Load in Rapid and Slow Progressors
Camp W, Allen S, Alvarez J, Jolly P, Weiss H, Phillips J, Karita E, Serufilira A, Vermund S. Serum Retinol and HIV-1 RNA Viral Load in Rapid and Slow Progressors. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1998, 18: 401-406. PMID: 9704954, DOI: 10.1097/00042560-199808010-00022.Peer-Reviewed Original ResearchConceptsSerum retinol levelsHIV-1 RNA viral loadLow viral loadLow serum retinol levelsRNA viral loadSlow progressorsRetinol levelsViral loadHIV serologySerum retinolDisease progressionFirst HIV-positive testHigher serum retinol levelsAsymptomatic HIV infectionHigh HIV loadLow serum retinolSerum retinol valuesHIV disease progressionHIV-positive testHigh viral loadThirty HIVHIV loadHIV infectionRapid progressorsSerum vitaminSerum Retinol and HIV-1 RNA Viral Load in Rapid and Slow Progressors
Camp W, Allen S, Alvarez J, Jolly P, Weiss H, Phillips J, Karita E, Serufilira A, Vermund S. Serum Retinol and HIV-1 RNA Viral Load in Rapid and Slow Progressors. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1998, 18: 21-26. PMID: 9593454, DOI: 10.1097/00042560-199805010-00004.Peer-Reviewed Original ResearchConceptsSerum retinol levelsLow viral loadHIV-1 RNA viral loadLow serum retinol levelsRNA viral loadSlow progressorsRetinol levelsViral loadHIV serologySerum retinolDisease progressionFirst HIV-positive testHigher serum retinol levelsAsymptomatic HIV infectionHigh HIV loadLow serum retinolSerum retinol valuesHIV disease progressionHIV-positive testHigh viral loadThirty HIVHIV loadHIV infectionRapid progressorsSerum vitamin
1991
Estimating the 1978–1990 and Future Spread of Human Immunodeficiency Virus Type 1 in Subgroups of Homosexual Men
Hoover D, Munoz A, Carey V, Chmiel J, Taylor J, Margolick J, Kingsley L, Vermund S. Estimating the 1978–1990 and Future Spread of Human Immunodeficiency Virus Type 1 in Subgroups of Homosexual Men. American Journal Of Epidemiology 1991, 134: 1190-1205. PMID: 1746529, DOI: 10.1093/oxfordjournals.aje.a116022.Peer-Reviewed Original ResearchConceptsSeroconversion ratesHomosexual menHuman immunodeficiency virus type 1 (HIV-1) infectionHuman immunodeficiency virus type 1Virus type 1 infectionImmunodeficiency virus type 1Kaplan-Meier methodHIV-1 infectionType 1 infectionAge 55 yearsHIV-1 epidemicVirus type 1AIDS diagnosisSeroconversionAnnual hazardHematologic variablesAge 55Type 1Survival methodsBisexual menHomosexual populationCohortMenAgeInfection