2022
Antiretroviral therapy resistance mutations among HIV infected people in Kazakhstan
Mukhatayeva A, Mustafa A, Dzissyuk N, Issanov A, Mukhatayev Z, Bayserkin B, Vermund SH, Ali S. Antiretroviral therapy resistance mutations among HIV infected people in Kazakhstan. Scientific Reports 2022, 12: 17195. PMID: 36229577, PMCID: PMC9562405, DOI: 10.1038/s41598-022-22163-7.Peer-Reviewed Original Research
2014
Health literacy predicts pediatric dosing accuracy for liquid zidovudine
Howard LM, Tique JA, Gaveta S, Sidat M, Rothman RL, Vermund SH, Ciampa PJ. Health literacy predicts pediatric dosing accuracy for liquid zidovudine. AIDS 2014, 28: 1041-1048. PMID: 24463393, PMCID: PMC4171732, DOI: 10.1097/qad.0000000000000197.Peer-Reviewed Original ResearchConceptsCombination antiretroviral therapyHIV infectionAntiretroviral medicationsDosing errorsPediatric HIV infectionCross-sectional studyHIV literacyAntiretroviral therapyMedication dosingHIV knowledgeMultivariable modelHealth literacyZidovudineTargeted interventionsCaregivers' abilityInfectionLimited literacyMedicationsSignificant differencesMaputo ProvinceAdultsLiteracy levelsAssociationSyringeDosing
2013
Haemoglobin recovery among HIV-1 infected patients on zidovudine-based antiretroviral therapy and other regimens in north-central Nigeria
Parrish DD, Blevins M, Megazzini KM, Shepherd BE, Mohammed MY, Wester CW, Vermund SH, Aliyu MH. Haemoglobin recovery among HIV-1 infected patients on zidovudine-based antiretroviral therapy and other regimens in north-central Nigeria. International Journal Of STD & AIDS 2013, 25: 355-359. PMID: 24104694, PMCID: PMC4385388, DOI: 10.1177/0956462413506887.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnemiaAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveDrug Therapy, CombinationFemaleHemoglobinsHIV InfectionsHumansLinear ModelsMaleMiddle AgedNigeriaRetrospective StudiesReverse Transcriptase InhibitorsRural PopulationSocioeconomic FactorsTime FactorsTreatment OutcomeZidovudineConceptsBaseline hemoglobin levelCombination antiretroviral therapyHemoglobin levelsAntiretroviral therapyHemoglobin recoveryNon-pregnant adult patientsUse of zidovudineZidovudine-containing regimenZidovudine-containing regimensNorth Central NigeriaGroup of patientsRural North-Central NigeriaMeasures of hemoglobinZidovudine useBaseline hemoglobinAdult patientsMedian hemoglobinHemoglobin responseHIV-1PatientsZidovudineHemoglobin dataHemoglobinRegimensTherapy
2011
Improving Retention in the Early Infant Diagnosis of HIV Program in Rural Mozambique by Better Service Integration
Ciampa PJ, Burlison JR, Blevins M, Sidat M, Moon TD, Rothman RL, Vermund SH. Improving Retention in the Early Infant Diagnosis of HIV Program in Rural Mozambique by Better Service Integration. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2011, 58: 115-119. PMID: 21546845, DOI: 10.1097/qai.0b013e31822149bf.Peer-Reviewed Original ResearchConceptsEarly infant diagnosisInfant diagnosisInfant testingEarly infant testingWomen/infantsRetrospective record reviewPostpartum HIVRural MozambiqueRecord reviewStandard referralHIV programsHigher oddsReferral processSimple interventionHIVReferralDiagnosisInfant retentionWomenService integrationInfants
2003
Mother-to-child HIV transmission prevention in Thailand: physician zidovudine use and willingness to provide care
Bhatta MP, Stringer JS, Phanuphak P, Vermund SH. Mother-to-child HIV transmission prevention in Thailand: physician zidovudine use and willingness to provide care. International Journal Of STD & AIDS 2003, 14: 404-410. PMID: 12816669, DOI: 10.1258/095646203765371303.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnti-HIV AgentsAttitude of Health PersonnelDrug UtilizationFamily PracticeFemaleGynecologyHealth Knowledge, Attitudes, PracticeHIV InfectionsHumansInfectious Disease Transmission, VerticalLogistic ModelsMaleMultivariate AnalysisObstetricsPhysiciansPractice Patterns, Physicians'PregnancyPregnancy Complications, InfectiousSurveys and QuestionnairesThailandZidovudineConceptsZidovudine useObstetric careChild HIV transmission preventionMultivariable logistic regression analysisPerinatal zidovudine prophylaxisCaesarean section deliveryChild HIV transmissionHIV-positive womenHIV transmission preventionPredictors of failureThai physiciansLogistic regression analysisAntiretroviral useAntiretroviral therapySection deliveryAntenatal careCaesarean sectionVaginal deliveryZidovudine prophylaxisHIV transmissionPregnant womenElective terminationPelvic examinationTransmission preventionHIV
2002
Prenatal HIV Counseling, Testing, and Antiretroviral Prophylaxis by Obstetric and Family Medicine Providers in Alabama
Nichols SA, Bhatta MP, Lewis J, Vermund SH. Prenatal HIV Counseling, Testing, and Antiretroviral Prophylaxis by Obstetric and Family Medicine Providers in Alabama. The American Journal Of The Medical Sciences 2002, 324: 305-309. PMID: 12495296, DOI: 10.1097/00000441-200212000-00003.Peer-Reviewed Original ResearchMeSH KeywordsAIDS SerodiagnosisAlabamaAnti-HIV AgentsDirective CounselingFamily PracticeFemaleHIVHIV InfectionsHumansInfectious Disease Transmission, VerticalPatient Acceptance of Health CarePatient Education as TopicPerinatal CarePractice Patterns, Physicians'PregnancyPregnancy Complications, InfectiousPrenatal CarePreventive Health ServicesUnited StatesZidovudineConceptsUniversal HIV counselingHIV counselingAntiretroviral prophylaxisUS Public Health Service recommendationsPublic Health Service recommendationsUniversal testingPrenatal HIV counselingVoluntary HIV testingFamily medicine providersFamily medicine practitionersSurvey of obstetricsZidovudine usePediatric HIVPregnant patientsHIV testingHIV transmissionPregnant womenPerinatal carePrenatal carePhysician specialtyPatient educationMedicine providersImplementation of recommendationsPrenatal counselingHIVEffect of nevirapine toxicity on choice of perinatal HIV prevention strategies.
Stringer JS, Sinkala M, Rouse DJ, Goldenberg RL, Vermund SH. Effect of nevirapine toxicity on choice of perinatal HIV prevention strategies. American Journal Of Public Health 2002, 92: 365-6. PMID: 11867311, PMCID: PMC1447080, DOI: 10.2105/ajph.92.3.365.Peer-Reviewed Original Research
1999
Rapid Communication CCR5 Genotype and Resistance to Vertical Transmission of HIV-1
Philpott S, Burger H, Charbonneau T, Grimson R, Vermund S, Visosky A, Nachman S, Kovacs A, Tropper P, Frey H, Weiser B. Rapid Communication CCR5 Genotype and Resistance to Vertical Transmission of HIV-1. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1999, 21: 189-193. PMID: 10421241, DOI: 10.1097/00126334-199907010-00002.Peer-Reviewed Original ResearchConceptsHIV-1 infectionHIV-1Vertical transmissionCCR5 genotypeHIV-1 infection statusHIV-1 vertical transmissionHIV-1-infected mothersPrimary HIV-1 infectionMacrophage-tropic strainsAfrican AmericansParenteral transmissionUninfected childrenChild transmissionInfected childrenInfected mothersInfected womenDelta32 mutationCCR5 receptorInfection statusWhite childrenCCR5MothersChildrenHomozygous genotypeAdditional strategiesPrevention of Mother-to-Child Transmission of HIV in Thailand: Physicians' Attitudes on Zidovudine Use, Pregnancy Termination, and Willingness to Provide Care.
Stringer J, Stringer E, Phanuphak P, Jetwana P, Reinprayoon D, Funkhouser E, Vermund S. Prevention of Mother-to-Child Transmission of HIV in Thailand: Physicians' Attitudes on Zidovudine Use, Pregnancy Termination, and Willingness to Provide Care. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1999, 21: 217-222. PMID: 10421245, DOI: 10.1097/00126334-199907010-00006.Peer-Reviewed Original ResearchConceptsZDV prophylaxisZidovudine usePregnant womenPregnancy terminationPrevention of motherPredictors of failureObstetrics/gynecologyLogistic regression modelsAntiretroviral therapyChild transmissionCesarean deliveryObstetric providersVaginal deliveryMultivariable analysisPelvic examinationMale genderPhysicians' attitudesHIVPhysician educationElective abortionPatientsWomenThai physiciansRegular mailProphylaxis
1996
Ethical issues for perinatal HIV trials in developing countries.
Phanuphak P, Vermund SH. Ethical issues for perinatal HIV trials in developing countries. AIDS Patient Care And STDs 1996, 7: 236-8. PMID: 11361714.Peer-Reviewed Original ResearchAnti-HIV AgentsControl GroupsDeveloping CountriesEthical RelativismEthics, MedicalFemaleGestational AgeHealth Care RationingHIV InfectionsHumansInfant, NewbornInfectious Disease Transmission, VerticalPregnancyPregnancy Complications, InfectiousPregnant WomenTherapeutic Human ExperimentationTreatment OutcomeZidovudine
1995
Zidovudine for the Prevention of Vertical HIV Transmission
Rouse D, Owen J, Goldenberg R, Vermund S. Zidovudine for the Prevention of Vertical HIV Transmission. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1995, 9: 401-407. PMID: 7600108, DOI: 10.1097/00042560-199508000-00011.Peer-Reviewed Original ResearchConceptsCongenital HIV infectionZDV useHIV infectionVertical human immunodeficiency virus (HIV) transmissionHuman immunodeficiency virus (HIV) transmissionAdverse effectsVertical HIV transmissionDrug-induced complicationsQuality-adjusted life yearsMarkov cohort simulationQuality of lifeDecision analysis modelUninfected childrenZDV therapyZDV treatmentAsymptomatic HIVNeonatal exposureZidovudine administrationHIV transmissionPregnant womenLife decrementsHypothetical cohortLife yearsCohort simulationHIV
1992
The Effects on Survival of Early Treatment of Human Immunodeficiency Virus Infection
Graham N, Zeger S, Park L, Vermund S, Detels R, Rinaldo C, Phair J. The Effects on Survival of Early Treatment of Human Immunodeficiency Virus Infection. New England Journal Of Medicine 1992, 326: 1037-1042. PMID: 1347907, DOI: 10.1056/nejm199204163261601.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virus (HIV) infectionImmunodeficiency virus infectionDevelopment of AIDSPneumocystis carinii pneumoniaPCP prophylaxisProlong survivalEarly treatmentRelative riskVirus infectionCell countUse of zidovudineUse of prophylaxisDiagnosis of AIDSHIV Type 1HIV-1 infectionBasis of CD4High-risk menInitial disease stateProbability of deathZidovudine usersZidovudine therapyImmunodeficiency syndromeCarinii pneumoniaClinical symptomsProphylaxis
1991
High risk of human papillomavirus infection and cervical squamous intraepithelial lesions among women with symptomatic human immunodeficiency virus infection
Vermund S, Kelley K, Klein R, Feingold A, Schreiber K, Munk G, Burk R. High risk of human papillomavirus infection and cervical squamous intraepithelial lesions among women with symptomatic human immunodeficiency virus infection. American Journal Of Obstetrics And Gynecology 1991, 165: 392-400. PMID: 1651648, DOI: 10.1016/0002-9378(91)90101-v.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virus (HIV) infectionSquamous intraepithelial lesionsHuman papillomavirus infectionImmunodeficiency virus infectionSymptomatic human immunodeficiency virus infectionHuman immunodeficiency virusIntraepithelial lesionsPapillomavirus infectionVirus infectionUninfected womenImmunodeficiency virusHigh riskHuman immunodeficiency virus-infected womenHuman immunodeficiency virus-related diseaseHuman immunodeficiency virus seropositiveCervical squamous intraepithelial lesionsHigh-risk womenCervical cytologic abnormalitiesVirus-related diseasesPublic health measuresAssociated immunosuppressionAsymptomatic womenCytologic abnormalitiesHuman papillomavirusHealth measuresEffect of zidovudine and Pneumocystis carinii pneumonia prophylaxis on progression of HIV-1 infection to AIDS
STUDY T, Graham N, Zeger S, Park L, Saah A, Phair J, Detels R, Vermund S, Ho M. Effect of zidovudine and Pneumocystis carinii pneumonia prophylaxis on progression of HIV-1 infection to AIDS. The Lancet 1991, 338: 265-269. PMID: 1677108, DOI: 10.1016/0140-6736(91)90414-k.Peer-Reviewed Original ResearchMeSH KeywordsAcquired Immunodeficiency SyndromeAerosolsCD4-Positive T-LymphocytesEvaluation Studies as TopicFollow-Up StudiesHIV SeropositivityHIV-1HumansLeukocyte CountMalePentamidinePneumonia, PneumocystisProspective StudiesRegression AnalysisRisk FactorsTime FactorsTrimethoprim, Sulfamethoxazole Drug CombinationZidovudineConceptsPneumocystis carinii pneumoniaEffect of zidovudineHIV-1 infectionPCP prophylaxisProbability of progressionLymphocytes/First episodePneumocystis carinii pneumonia prophylaxisHIV-1-infected individualsHIV-1-seropositive menMonth intervalsPrimary PCP prophylaxisEfficacy of zidovudinePresence of HIVRate of progressionMultivariate log-linear modelPneumonia prophylaxisMore CD4Primary prophylaxisZidovudine therapyLymphocyte countCarinii pneumoniaClinical trialsObservational studyProphylaxisZidovudine use in AIDS-free HIV-1-seropositive homosexual men in the Multicenter AIDS Cohort Study (MACS), 1987-1989.
Graham NM, Zeger SL, Kuo V, Jacobson LP, Vermund SH, Phair JP, Detels R, Rinaldo CR, Saah AJ. Zidovudine use in AIDS-free HIV-1-seropositive homosexual men in the Multicenter AIDS Cohort Study (MACS), 1987-1989. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1991, 4: 267-76. PMID: 1671411.Peer-Reviewed Original ResearchConceptsHIV-1 seropositive homosexual menZidovudine useVisit 11Clinical variablesClinical trialsHomosexual menVisit 7Multicenter AIDS Cohort StudyLymphocytes/mm3Major clinical variablesClinical trial participationAIDS Cohort StudyClinical trial participantsSeropositive participantsZidovudine therapyCohort studyHigher treatment ratesLymphocyte levelsLymphocyte numbersNonclinical factorsAIDS patientsTrial participationSymptom statusOverall prevalenceOdds ratioNational AIDS incidence trends and the extent of zidovudine therapy in selected demographic and transmission groups.
Rosenberg PS, Gail MH, Schrager LK, Vermund SH, Creagh-Kirk T, Andrews EB, Winkelstein W, Marmor M, Des Jarlais DC, Biggar RJ. National AIDS incidence trends and the extent of zidovudine therapy in selected demographic and transmission groups. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1991, 4: 392-401. PMID: 2007974.Peer-Reviewed Original ResearchConceptsIntravenous drug usersAIDS incidence trendsIncidence trendsDrug usersHeterosexual contactSevere immunodeficiencyHeterosexual intravenous drug usersHuman immunodeficiency virus (HIV) infectionFavorable trendTransmission groupImmunodeficiency virus infectionIncidence of AIDSCases of AIDSZidovudine therapyTransfusion recipientsVirus infectionNumber of casesZidovudineNew York CityEarly cessationTherapyAIDSMenGay menSan Francisco
1990
How can epidemiology assist in guiding interventions for the acquired immunodeficiency syndrome/human immunodeficiency virus?
Vermund S, Hoth D. How can epidemiology assist in guiding interventions for the acquired immunodeficiency syndrome/human immunodeficiency virus? Annals Of Epidemiology 1990, 1: 141-155. PMID: 1669495, DOI: 10.1016/1047-2797(90)90005-d.Peer-Reviewed Original ResearchConceptsNew therapiesHIV infectionTherapeutic trialsClinical trialsImmunodeficiency syndrome/human immunodeficiency virusVaccine developmentHuman immunodeficiency virus (HIV) infectionRecent drug trialsImmunodeficiency virus infectionDevelopment of AIDSHost immunologic responseHuman immunodeficiency virusSuch clinical parametersFuture epidemiologic researchClinical therapeutic researchNatural history studiesUse of condomsEffect of treatmentClinical research methodsVariety of treatmentsAIDS/HIV epidemicClinical courseClinical outcomesClinical parametersImmunodeficiency virus