2000
Cytokine Profile in Genital Tract Secretions from Female Adolescents: Impact of Human Immunodeficiency Virus, Human Papillomavirus, and Other Sexually Transmitted Pathogens
Crowley-Nowick P, Ellenberg J, Vermund S, Douglas S, Holland C, Moscicki A. Cytokine Profile in Genital Tract Secretions from Female Adolescents: Impact of Human Immunodeficiency Virus, Human Papillomavirus, and Other Sexually Transmitted Pathogens. The Journal Of Infectious Diseases 2000, 181: 939-945. PMID: 10720516, DOI: 10.1086/315311.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentCervix MucusCytokinesEnzyme-Linked Immunosorbent AssayFemaleGenital Diseases, FemaleHIV InfectionsHumansInterleukin-10Interleukin-12Interleukin-2Multivariate AnalysisPapillomaviridaePapillomavirus InfectionsRegression AnalysisSexually Transmitted DiseasesTumor Virus InfectionsConceptsIL-12 concentrationsHuman immunodeficiency virusIL-10Human papillomavirusIL-12Immunodeficiency virusHigher IL-10 concentrationsHIV-positive patientsIL-10 concentrationsGenital tract infectionGenital tract secretionsIL-2 concentrationsQuantitative enzyme-linked immunosorbent assayFemale adolescentsEnzyme-linked immunosorbent assayCytokine profileNegative patientsTract infectionsCervical secretionsConcomitant infectionImmunoregulatory cytokinesTract secretionsGenital tractHIVImmunosorbent assayPrevalence of and Risks for Cervical Human Papillomavirus Infection and Squamous Intraepithelial Lesions in Adolescent Girls: Impact of Infection With Human Immunodeficiency Virus
Moscicki AB, Ellenberg JH, Vermund SH, Holland CA, Darragh T, Crowley-Nowick PA, Levin L, Wilson CM. Prevalence of and Risks for Cervical Human Papillomavirus Infection and Squamous Intraepithelial Lesions in Adolescent Girls: Impact of Infection With Human Immunodeficiency Virus. JAMA Pediatrics 2000, 154: 127-134. PMID: 10665598, DOI: 10.1001/archpedi.154.2.127.Peer-Reviewed Original ResearchConceptsSquamous intraepithelial lesionsHPV infectionHuman papillomavirus infectionIntraepithelial lesionsPapillomavirus infectionHIV infectionHIV statusCervical human papillomavirus infectionLow-risk HPV typesCourse of HIVNormal cytologic findingsCD4 cell countCervical HPV infectionT-cell countsT-cell immunosuppressionHuman immunodeficiency virusHigh-risk typesAdolescent girlsSexual risk behaviorsImpact of infectionCD4 immunosuppressionBaseline visitHPV typesRisky sexual behaviorViral load
1996
Pregnancy and cervical infection with human papillomaviruses
Morrison E, Gammon MD, Goldberg GL, Vermund SH, Burk RD. Pregnancy and cervical infection with human papillomaviruses. International Journal Of Gynecology & Obstetrics 1996, 54: 125-130. PMID: 9236309, DOI: 10.1016/0020-7292(96)02694-x.Peer-Reviewed Original ResearchConceptsPrevalence odds ratiosHPV risk factorsRisk factorsHPV infectionCurrent pregnancyCervical HPV infectionPrevalence of HPVHuman papillomavirus infectionAssociation of pregnancyStatistical significanceLarge municipal hospitalSelf-administered questionnaireRace/ethnicityCervicovaginal lavageCervical infectionPapillomavirus infectionHPV DNAGestational ageGynecological examinationOutpatient clinicHuman papillomavirusSignificant confoundersOdds ratioLavage samplesMunicipal HospitalDeclining Prevalence of Cervicovaginal Human Papillomavirus Infection With Age Is Independent of Other Risk Factors
BURK R, KELLY P, FELDMAN J, BROMBERG J, VERMUND S, DEHOVITZ J, LANDESMAN S. Declining Prevalence of Cervicovaginal Human Papillomavirus Infection With Age Is Independent of Other Risk Factors. Sexually Transmitted Diseases 1996, 23: 333-341. PMID: 8836027, DOI: 10.1097/00007435-199607000-00013.Peer-Reviewed Original ResearchConceptsPrevalence of HPVHuman papillomavirus infectionHPV infectionPapillomavirus infectionRisk factorsCervicovaginal human papillomavirus infectionGenital HPV infectionCervical HPV infectionWomen 45 yearsFemale genital tractLogistic regression analysisYears of ageSexual behaviorInner-city womenAge-dependent declineHPV immunityHPV prevalenceCervical diseaseCervicovaginal cellsGenital tractLow prevalenceOlder womenSex partnersYounger ageBiologic effects
1995
Prevalence of Human Papillomavirus Among STD Clinic Attenders in Jamaica
FIGUEROA J, WARD E, LUTHI T, VERMUND S, BRATHWAITE A, BURK R. Prevalence of Human Papillomavirus Among STD Clinic Attenders in Jamaica. Sexually Transmitted Diseases 1995, 22: 114-118. PMID: 7624812, DOI: 10.1097/00007435-199503000-00007.Peer-Reviewed Original ResearchConceptsHuman papillomavirus infectionHuman papillomavirusPapillomavirus infectionSTD clinicOlder womenHigh HPV prevalenceHuman papillomavirus (HPV) prevalencePrevalence of HPVSTD clinic attendersIncidence of cancerMajor etiologic agentHuman papillomavirus (HPV) genomeLow-stringency Southern blot hybridizationCross-sectional surveyHPV prevalenceEffect of ageClinic attendersCervical cancerWomen 25Risk factorsWomen 20Effective vaccineLow prevalenceWomen 15Etiologic agent
1994
Risk Factors For Squamous Intraepithelial Lesions On Pap Smear In Women At Risk For Human Immunodeficiency Virus Infection
Klein R, Ho G, Vermund S, Fleming I, Burk R. Risk Factors For Squamous Intraepithelial Lesions On Pap Smear In Women At Risk For Human Immunodeficiency Virus Infection. The Journal Of Infectious Diseases 1994, 170: 1404-1409. PMID: 7995978, DOI: 10.1093/infdis/170.6.1404.Peer-Reviewed Original ResearchMeSH KeywordsAdultCarcinoma, Squamous CellCD4 Lymphocyte CountDNA, ViralFemaleHIV AntibodiesHIV InfectionsHumansImmunocompromised HostMiddle AgedMultivariate AnalysisNew YorkOdds RatioPapanicolaou TestPapillomaviridaePapillomavirus InfectionsPrevalenceRisk FactorsTumor Virus InfectionsUterine Cervical DysplasiaUterine Cervical NeoplasmsVaginal SmearsConceptsSquamous intraepithelial lesionsHuman immunodeficiency virus (HIV) infectionImmunodeficiency virus infectionRisk factorsHPV infectionHIV infectionIntraepithelial lesionsPap smearVirus infectionHigh-risk HPV typesGenital HPV infectionHIV antibody testingIndependent risk factorSevere HIVSevere immunosuppressionHPV typesAntibody testingGenital HPVUnivariate analysisMultivariate analysisInfectionGenome detectionImmunosuppressionRiskLesions
1992
Genital Human Papillomavirus Infection in Women
Kelley K, Galbraith M, Vermund S. Genital Human Papillomavirus Infection in Women. Journal Of Obstetric Gynecologic & Neonatal Nursing 1992, 21: 503-515. PMID: 1337355, DOI: 10.1111/j.1552-6909.1992.tb01771.x.Peer-Reviewed Original ResearchConceptsGenital human papillomavirus (HPV) infectionHuman papillomavirus infectionHuman papillomavirusCervical neoplasiaHPV infectionPapillomavirus infectionHIV infectionPapanicolaou testRisk factorsPrevalence of HPVCervical intraepithelial lesionsPutative precursor lesionsOutcome of therapyEffective screening toolAbnormal cervical cellsHPV typesIntraepithelial lesionsCervical cancerCondylomata acuminataPrecursor lesionsClinicians' knowledgeNeoplasiaInfectionLiterature searchYoung womenFollow-up evaluation of cervicovaginal human papillomavirus infection in adolescents
Rosenfeld W, Rose E, Vermund S, Schreiber K, Burk R. Follow-up evaluation of cervicovaginal human papillomavirus infection in adolescents. The Journal Of Pediatrics 1992, 121: 307-311. PMID: 1322456, DOI: 10.1016/s0022-3476(05)81212-0.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBlotting, SouthernCervix UteriFemaleFollow-Up StudiesHumansIncidenceNew YorkPapillomaviridaeSexual BehaviorTumor Virus InfectionsVaginaConceptsHPV infectionCervicovaginal human papillomavirus infectionGenotype-specific HPV infectionPositive HPV test resultHPV test resultsHuman papillomavirus infectionSame HPV typeHPV DNA detectionHuman papillomavirus DNAUrban teaching hospitalCervicovaginal lavagePapillomavirus infectionHPV typesFemale patientsTeaching hospitalPapillomavirus DNASecond examinationSecond visitPatientsInfectionVisitsHPVSouthern blot hybridizationBlot hybridizationDNA detectionGenital papillomavirus infection and cervical dysplasia—opportunistic complications of hiv infection
Laga M, Icenogle J, Marsella R, Manoka A, Nzila N, Ryder R, Vermund S, Heyward W, Nelson A, Reeves W. Genital papillomavirus infection and cervical dysplasia—opportunistic complications of hiv infection. International Journal Of Cancer 1992, 50: 45-48. PMID: 1309459, DOI: 10.1002/ijc.2910500110.Peer-Reviewed Original ResearchConceptsCervical intra-epithelial neoplasiaHuman genital papillomavirusesHPV infectionOpportunistic complicationsSeronegative womenHIV infectionHPV typesCervical cancerPap smearHuman immunodeficiency virus (HIV) infectionHIV-seropositive womenHPV DNA testingImmunodeficiency virus infectionIntra-epithelial neoplasiaGenital papillomavirus infectionAno-genital cancersGenital HPV typesCervicovaginal lavageSeropositive womenHIV seropositivityPapillomavirus infectionCervical diseaseCervical dysplasiaHPV DNAImmunodeficiency syndrome
1991
Human papillomavirus, gonorrhea, syphilis, and cervical dysplasia in jailed women.
Bickell NA, Vermund SH, Holmes M, Safyer S, Burk RD. Human papillomavirus, gonorrhea, syphilis, and cervical dysplasia in jailed women. American Journal Of Public Health 1991, 81: 1318-20. PMID: 1928533, PMCID: PMC1405301, DOI: 10.2105/ajph.81.10.1318.Peer-Reviewed Original ResearchConceptsHuman papillomavirusPap smearRoutine intake proceduresAbnormal Pap smearsBehavioral risk factorsNew York City jailsCervicovaginal lavageSerologic syphilisHPV infectionCervical diseaseCervical dysplasiaCervical cytologyRisk factorsIntake proceduresFemale detaineesWomenPapillomavirusSyphilisHigh rateCity jailsDiseaseSmearsIncarcerated womenLavageGonorrheaHuman papillomavirus infection and other risk factors for cervical neoplasia: A case‐control study
Morrison E, Ho G, Vermund S, Goldberg G, Kadish A, Kelley K, Burk R. Human papillomavirus infection and other risk factors for cervical neoplasia: A case‐control study. International Journal Of Cancer 1991, 49: 6-13. PMID: 1874571, DOI: 10.1002/ijc.2910490103.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsBase SequenceBlotting, SouthernCarcinomaCase-Control StudiesEpitheliumFemaleHumansMolecular Sequence DataMultivariate AnalysisOligonucleotidesPolymerase Chain ReactionRegression AnalysisRisk FactorsSocioeconomic FactorsTumor Virus InfectionsUterine Cervical DiseasesUterine Cervical NeoplasmsConceptsSquamous intraepithelial lesionsCervical squamous intraepithelial lesionsIndependent risk factorHPV infectionRisk factorsHigh riskCervical neoplasiaMajor independent risk factorLow educational achievementHuman papillomavirus infectionAssociation of HPVHPV types 16Major risk factorCase-control studyLogistic regression analysisCase-control designLogistic regression modelsRisk of diseaseHPV screeningIntraepithelial lesionsPapillomavirus infectionHPV typesViral loadBorderline significanceNormal womenHigh risk of human papillomavirus infection and cervical squamous intraepithelial lesions among women with symptomatic human immunodeficiency virus infection
Vermund S, Kelley K, Klein R, Feingold A, Schreiber K, Munk G, Burk R. High risk of human papillomavirus infection and cervical squamous intraepithelial lesions among women with symptomatic human immunodeficiency virus infection. American Journal Of Obstetrics And Gynecology 1991, 165: 392-400. PMID: 1651648, DOI: 10.1016/0002-9378(91)90101-v.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virus (HIV) infectionSquamous intraepithelial lesionsHuman papillomavirus infectionImmunodeficiency virus infectionSymptomatic human immunodeficiency virus infectionHuman immunodeficiency virusIntraepithelial lesionsPapillomavirus infectionVirus infectionUninfected womenImmunodeficiency virusHigh riskHuman immunodeficiency virus-infected womenHuman immunodeficiency virus-related diseaseHuman immunodeficiency virus seropositiveCervical squamous intraepithelial lesionsHigh-risk womenCervical cytologic abnormalitiesVirus-related diseasesPublic health measuresAssociated immunosuppressionAsymptomatic womenCytologic abnormalitiesHuman papillomavirusHealth measuresPlasma ascorbic acid and beta-carotene levels in women evaluated for HPV infection, smoking, and cervix dysplasia.
Basu J, Palan PR, Vermund SH, Goldberg GL, Burk RD, Romney SL. Plasma ascorbic acid and beta-carotene levels in women evaluated for HPV infection, smoking, and cervix dysplasia. Cancer Epidemiology 1991, 15: 165-70. PMID: 1647869.Peer-Reviewed Original ResearchConceptsBeta-carotene levelsHPV infectionCervical dysplasiaClinical statusPap smearPeripheral venous blood samplesImportance of smokingRepeat Pap smearHuman papillomavirus infectionAbnormal Pap smearsVenous blood samplesGrades of severityPlasma ascorbic acidAscorbic acid levelsCervix dysplasiaColposcopy clinicHPV statusPapillomavirus infectionLavage specimenPlasma levelsMean plasmaDysplastic groupBlood samplesDysplasiaSmoking
1990
Cervical cytologic abnormalities and papillomavirus in women infected with human immunodeficiency virus.
Feingold AR, Vermund SH, Burk RD, Kelley KF, Schrager LK, Schreiber K, Munk G, Friedland GH, Klein RS. Cervical cytologic abnormalities and papillomavirus in women infected with human immunodeficiency virus. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1990, 3: 896-903. PMID: 2166784.Peer-Reviewed Original ResearchConceptsSquamous intraepithelial lesionsHIV-positive womenCervical cytologic abnormalitiesCytologic abnormalitiesCervical cytologyAsymptomatic HIV-positive womenHuman immunodeficiency virus (HIV) infectionHIV-negative womenHuman papillomavirus infectionImmunodeficiency virus infectionSymptomatic HIV infectionIntravenous drug useHuman immunodeficiency virusIntravenous drug usersFemale genital tractWestern blot confirmationCervicovaginal lavageHPV determinationSeronegative womenHPV infectionPapillomavirus infectionCytological lesionsHIV infectionIntraepithelial lesionsImmunodeficiency virus
1989
High Prevalence Rate of Human Papillomavirus Infection and Association With Abnormal Papanicolaou Smears in Sexually Active Adolescents
Rosenfeld WD, Vermund SH, Wentz SJ, Burk RD. High Prevalence Rate of Human Papillomavirus Infection and Association With Abnormal Papanicolaou Smears in Sexually Active Adolescents. JAMA Pediatrics 1989, 143: 1443-1447. PMID: 2556023, DOI: 10.1001/archpedi.1989.02150240065018.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultFemaleHumansPapanicolaou TestPapillomaviridaeRisk FactorsSexTumor Virus InfectionsVaginal SmearsConceptsAbnormal Papanicolaou smearsHuman papillomavirusHPV infectionHPV DNACytologic abnormalitiesPapanicolaou smearsPrevalence ratesLow-grade cervical intraepithelial neoplasiaRoutine cervical cytologic screeningMultiple lifetime sexual partnersHuman papillomavirus infectionCervical intraepithelial neoplasiaHPV types 6/11Cervical epithelial abnormalitiesCervical cytologic screeningHigh prevalence ratesYears of ageLifetime sexual partnersCervicovaginal lavageHPV presentUninfected patientsPapillomavirus infectionCervical neoplasiaCytologic screeningIntraepithelial neoplasiaComparison of Cytobrush and cervicovaginal lavage sampling methods for the detection of genital human papillomavirus
Goldberg G, Vermund S, Schiffman M, Ritter D, Spitzer C, Burk R. Comparison of Cytobrush and cervicovaginal lavage sampling methods for the detection of genital human papillomavirus. American Journal Of Obstetrics And Gynecology 1989, 161: 1669-1672. PMID: 2557764, DOI: 10.1016/0002-9378(89)90947-2.Peer-Reviewed Original ResearchMeSH KeywordsBlotting, SouthernCervix UteriDNA, ViralFemaleHumansPapillomaviridaeSpecimen HandlingTumor Virus InfectionsVaginaVaginal SmearsConceptsHuman papillomavirus deoxyribonucleic acidCervicovaginal lavageHuman papillomavirusGenital human papillomavirusFemale lower genital tractNoninvasive methodHuman papillomavirus infectionLower genital tractSensitive noninvasive methodExfoliated cervical cellsComparison of cytobrushSubstantial clinical importanceColposcopy clinicPapillomavirus infectionCervical neoplasiaGenital tractLavagePapillomavirusClinical importanceEtiologic agentCervical cellsPatientsDeoxyribonucleic acidSouthern blot hybridizationCellsMolecular diagnosis of genital human papillomavirus infection: Comparison of two methods used to collect exfoliated cervical cells
Vermund S, Schiffman M, Goldberg G, Ritter D, Weltman A, Burk R. Molecular diagnosis of genital human papillomavirus infection: Comparison of two methods used to collect exfoliated cervical cells. American Journal Of Obstetrics And Gynecology 1989, 160: 304-308. PMID: 2537011, DOI: 10.1016/0002-9378(89)90430-4.Peer-Reviewed Original ResearchConceptsHuman papillomavirus infectionCervicovaginal lavagePapillomavirus infectionHuman papillomavirusLavage methodGenital human papillomavirus (HPV) infectionGenital tract infectionHuman papillomavirus detectionHuman papillomavirus typesDevelopment of neoplasiaCell collection methodsTract infectionsEndocervical swabsColposcopic examinationPapillomavirus detectionPapanicolaou testInvasive carcinomaPapillomavirus typesLavageEtiologic agentClinical investigatorsWomen resultsCell collectionVirus typeInfection
1988
Detection of human papillomavirus deoxyribonucleic acid in exfoliated cervicovaginal cells as a predictor of cervical neoplasia in a high-risk population
Ritter D, Kadish A, Vermund S, Romney S, Villari D, Burk R. Detection of human papillomavirus deoxyribonucleic acid in exfoliated cervicovaginal cells as a predictor of cervical neoplasia in a high-risk population. American Journal Of Obstetrics And Gynecology 1988, 159: 1517-1525. PMID: 2849881, DOI: 10.1016/0002-9378(88)90587-x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedBiopsyCarcinoma, Squamous CellCervix UteriDNA, ViralFemaleForecastingHumansMiddle AgedPapanicolaou TestPapillomaviridaeRisk FactorsSensitivity and SpecificityTherapeutic IrrigationTumor Virus InfectionsUterine Cervical DiseasesUterine Cervical NeoplasmsVaginaVaginal SmearsConceptsHuman papillomavirus detectionHuman papillomavirus deoxyribonucleic acidHuman papillomavirus typesHuman papillomavirus type 16Cervical lesionsHuman papillomavirusPapillomavirus detectionPapillomavirus type 16Cervicovaginal lavageCytologic examinationPapillomavirus typesType 16Older womenHuman papillomavirus-negative womenPositive findingsCancerous lesionsAbnormal cytologic findingsHospital colposcopy clinicHuman papillomavirus infectionHigh-risk populationNegative cytologic resultsYears of ageHuman papillomavirus type 18Colposcopy clinicPapillomavirus infection