2002
Host genetic profiles predict virological and immunological control of HIV-1 infection in adolescents
Tang J, Wilson CM, Meleth S, Myracle A, Lobashevsky E, Mulligan MJ, Douglas SD, Korber B, Vermund SH, Kaslow RA. Host genetic profiles predict virological and immunological control of HIV-1 infection in adolescents. AIDS 2002, 16: 2275-2284. PMID: 12441799, DOI: 10.1097/00002030-200211220-00007.Peer-Reviewed Original ResearchConceptsViral loadHLA class IHost genetic profileHIV-1-infected adolescentsHIV-1-seropositive participantsCD4 T-cell countClass IHIV-seronegative individualsT-cell countsCD4 T lymphocytesHIV-1 infectionHIV-1 pathogenesisGenetic profileClinical patient groupsAntiretroviral therapyQuarterly followMultivariable analysisHealth cohortPatient groupImmunological outcomesImmunological controlNegative HLAT lymphocytesProtective effectAdolescent care
1990
How can epidemiology assist in guiding interventions for the acquired immunodeficiency syndrome/human immunodeficiency virus?
Vermund S, Hoth D. How can epidemiology assist in guiding interventions for the acquired immunodeficiency syndrome/human immunodeficiency virus? Annals Of Epidemiology 1990, 1: 141-155. PMID: 1669495, DOI: 10.1016/1047-2797(90)90005-d.Peer-Reviewed Original ResearchConceptsNew therapiesHIV infectionTherapeutic trialsClinical trialsImmunodeficiency syndrome/human immunodeficiency virusVaccine developmentHuman immunodeficiency virus (HIV) infectionRecent drug trialsImmunodeficiency virus infectionDevelopment of AIDSHost immunologic responseHuman immunodeficiency virusSuch clinical parametersFuture epidemiologic researchClinical therapeutic researchNatural history studiesUse of condomsEffect of treatmentClinical research methodsVariety of treatmentsAIDS/HIV epidemicClinical courseClinical outcomesClinical parametersImmunodeficiency virus